Summary

Other Scenarios:

Buyer: Pharmaceutical Product Development, Inc. (PPDI) Last Price: 33.19 Market Cap.: 3.78B
Target: PDL BioPharma Inc. (PDLI) Last Price: 6.30 Market Cap.: 880.71M

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
Healthcare 741
Biopharmaceuticals 337
Healthcare Services   129
Outsourced Biomedical Services 39
Technology   808
Information Technology (IT) Services   105
Software   245

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business

Buyer (Total: 21)
  • PPD Complete Drug Development Services
  • PPD Discovery Sciences Preclinical Services
  • BioDuro LLC
  • Austin Central Laboratory/Global Central Laboratories
Target (Total: 5)
  • Humanized Antibody Technology
Buyer
  • Dapoxetine
  • PPD Complete Drug Development Services
  • CSS Informatics Consulting Services
  • Clinical Trial Software Consulting
Target
  • Nuvion (Visilizumab)
  • Soliris (Eculizumab)
  • Therapeutic Antibody Candidates
  • Zenapax (Daclizumab)

Business Relationship Summary:

Top Key Suppliers

Top Key Customers

Buyer (Total: 0)

n/a

Target (Total: 1)
  • Roche Holding Ltd. (ADR) (RHHBY)
Buyer (Total: 2)
  • Chemokine Therapeutics Corp. (CHKT)
  • Government - United States
Target (Total: 7)
  • Roche Holding Ltd. (ADR) (RHHBY)
  • Elan Corporation, plc (ADR) (ELN)
  • Pfizer Inc. (PFE)
  • Bristol Myers Squibb Co. (BMY)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 11,000 8
Revenue Per Employee 148,662.9 61,231,260.0
Total Revenue 415.4 83.8
Total Expenses 350.0 4.0
Other Revenue n/a n/a
Cost of Revenue 223.5 n/a
SG&A Expense 107.6 3.9
Research & Development 2.1 n/a
Other Operating Expense n/a n/a
Operating Income 65.4 79.8
Unusual Income n/a n/a
LT Debt to Capital n/a 350.87
Fwd P/E 20.89 5.42
Fwd P/Rev 2.46 2.38
Book Value 1,191.3 -243.2
Curr Portion of LTD/Cap Lease n/a 115.3

Individual Company Summary

Focused

Buyer

Focused (): Healthcare > Outsourced Biomedical Services > Development/Manufacturing Services > Contract Research Organizations (CRO) > Full Service

Target

Focused (): Healthcare > Outsourced Biomedical Services > Drug Discovery Services > Lead Discovery/Validation/Optimization > Lead Biologics > Antibodies

Business Description

Buyer

Pharmaceutical Product Development, Inc. (PPD) is a global contract research organization providing drug discovery, development and lifecycle management services. The Company?s clients and partners include pharmaceutical, biotechnology, medical device, academic, non-profit and government organizations. Its development services include preclinical drug discovery services, programs, Phase I through Phase IV clinical development services and post-approval services, as well as bioanalytical, good manufacturing practices (cGMP), global central laboratory and vaccines and biologics laboratory services. It also offers support, such as medical information, patient compliance programs, patient and disease registry programs, product safety and pharmacovigilance, standard response document development, observational studies, Phase IV monitored studies and prescription-to-over-the-counter (Rx to OTC), programs. It operates in two segments: Clinical Development Services and Laboratory Services.

Target

PDL BioPharma, Inc. (PDL) is engaged in the management of its antibody humanization patents and royalty assets, which consist of its Queen et al. patents and license agreements with pharmaceutical and biotechnology companies. The Company receives royalties based on these license agreements on sales of a number of humanized antibody products marketed and also may receive royalty payments on additional humanized antibody products launched before final patent expiry in December 2014. The Company has entered into licensing agreements with numerous entities that are independently developing or have developed humanized antibodies pursuant to which it has licensed certain rights under its Queen et al. patents to make, use, sell, offer for sale and import humanized antibodies. It receives royalties on net sales of products that are made, used or sold prior to patent expiry. In general, these agreements cover antibodies targeting antigens specified in the license agreements.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 46.7 100
Operating Margin % 14.65 67.76
Quick Ratio 1.54 1.12
Current Ratio 1.69 1.26
Coverage Ratio n/a n/a
Total Assets 1,950.9 270.5
Return on Equity % 55.7 n/a
Return on Assets % 34.01 201.07
Cash+ ST Inv. Per Share 4.17 1.17
Total Debt 0.0 455.5
Total Debt to Equity % 0 0
Total Debt to Tangible Equity % 0 n/a
Debt to Asset % 0.00 168.36

Product Summary

Sector Buyer Target
Healthcare
Biopharmaceuticals
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
 
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
 
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
 
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
 
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
 
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
 
Healthcare Services  
Healthcare Support Services
The Support Services Subsector is comprised of companies that provide non-medical services for managing, enhancing, facilitating, and enabling the healthcare delivery process.
 
Outsourced Biomedical Services
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Buyer Products:

  • PPD Complete Drug Development Services
  • PPD Discovery Sciences Preclinical Services
  • BioDuro LLC
  • Austin Central Laboratory/Global Central Laboratories
  • Bioanalytical Laboratories
 
Development/Manufacturing Services
The Development/Manufacturing Services Subsector includes companies that provide research, development, manufacturing, sales and marketing to biopharmaceutical and medical device companies.
 
Drug Discovery Services
The Drug Discovery Services Subsector includes companies that provide biopharmaceutical companies with novel biological targets and drug leads.
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting
Information technology related to consulting services designed to improve a client company's operating efficiency, and business capabilities through the expert application of information technology resources and best practices. These services can be delivered on a project-by-project basis, or via an on-going relationship.
 
Software  
Industry-Specific
Software that has functionality specific to a vertical industry.
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
Healthcare
Biopharmaceuticals
Digestive System  
Gastrointestinal Tract Disorders  
Intestinal Disorders  
Inflammatory Bowel Disease (IBD)  
Ulcerative Colitis  
Monoclonal Antibodies
Therapeutics that treat ulcerative colitis through modulation of immune pathways implicated in the progression of the disease.

Target Products:

  • Nuvion (Visilizumab)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Target Products:

  • Nuvion (Visilizumab)
 
Hematology  
Red Blood Cell (RBC) Disorders  
Hemoglobinuria  
Monoclonal Antibodies
Therapeutics that treat hemoglobinuria by specifically binding to the C5 complement component and inhibiting its activation.

Target Products:

  • Soliris (Eculizumab)
 
Immunology  
Autoimmune Disorders  
Inflammatory Bowel Disease (IBD)  
Ulcerative Colitis  
Monoclonal Antibodies
Therapeutics that treat ulcerative colitis through modulation of immune pathways implicated in the progression of the disease.

Target Products:

  • Nuvion (Visilizumab)
 
Immune Deficiency Disorders  
Atypical Hemolytic Uremic Syndrome (aHUS)  
Monoclonal Antibodies
Therapeutics that treat Atypical Hemolytic Uremic Syndrome by specifically binding certain receptors implicated with the disease.

Target Products:

  • Soliris (Eculizumab)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Target Products:

  • Nuvion (Visilizumab)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Target Products:

  • Therapeutic Antibody Candidates
 
Oncology  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Target Products:

  • Therapeutic Antibody Candidates
 
Transplantation  
Renal (Kidney)  
Rejection Prophylaxis  
Monoclonal Antibodies
Protein-based therapeutics that target specific substances like proteins.

Target Products:

  • Zenapax (Daclizumab)
 
Urology  
Male Genital Disorders  
Penile  
Premature Ejaculation  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat premature ejaculation by selectively preventing the removal of serotonin.

Buyer Products:

  • Dapoxetine
 
Healthcare Services  
Healthcare Support Services  
Consulting
Services providing advice, assistance, and information to a wide range of healthcare companies, including pharmaceutical, medical devices, and health services companies.

Buyer Products:

  • PPD Complete Drug Development Services
 
Outsourced Biomedical Services
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Buyer Products:

  • PPD Complete Drug Development Services
  • PPD Discovery Sciences Preclinical Services
  • BioDuro LLC
  • Austin Central Laboratory/Global Central Laboratories
  • Bioanalytical Laboratories
 
Development/Manufacturing Services  
Chemistry Services
Outsourced companies that provide medicinal chemistry, organic synthesis, process research, cGMP synthesis, and analytical services to the biopharmaceutical industry.

Buyer Products:

  • BioDuro LLC
 
Contract Research Organizations (CRO)  
Full Service
Contract Research Organizations (CROs) that conduct both preclinical and clinical studies in the development of new therapeutic products.

Buyer Products:

  • PPD Complete Drug Development Services
 
Limited Service  
Clinical
Limited Service Contract Research Organizations that design, manage, and monitor human studies of new therapeutics. Other services include project management, patient recruitment, data management, biostatistical analysis, medical and regulatory affairs, and quality assurance.

Buyer Products:

  • Phases II through IV Clinical Trial Management Services
  • Government Services
  • Dental Research Clinic
  • Austin Central Laboratory/Global Central Laboratories
  • PPD Device Testing Services
  • PPD Phase I Clinical Testing Services
 
Preclinical
Limited Service Contract Research Organizations that design, manage, and monitor animal studies of new therapeutics. In addition to animal studies, these limited service companies also provide formulation development services.

Buyer Products:

  • BioDuro LLC
  • cGMP Laboratory
  • PPD Discovery Sciences Preclinical Services
 
Sales/Marketing
Outsourced companies that provide biopharmaceutical and medical device companies with contract sales and marketing services.

Buyer Products:

  • Post-Approval And Market Development Support Services
 
Drug Discovery Services
Lead Discovery/Validation/Optimization
Assay Development
Bioanalytical services that are used to develop biologically based tests for use in high throughput screening (HTS).

Buyer Products:

  • Biomarker Discovery Sciences
  • BioDuro LLC
 
Combinatorial Chemistry Libraries
Drug discovery companies that provide biopharmaceutical companies a library of combinatorial chemical compounds used for testing.

Buyer Products:

  • BioDuro LLC
 
Combinatorial Services
Drug discovery companies that provide biopharmaceutical companies combinatorial chemistry services.

Buyer Products:

  • BioDuro LLC
 
High Throughput Screening (HTS)
Bioanalytical services that allow for the biological testing of up to 10,000 compounds each day.

Buyer Products:

  • BioDuro LLC
 
Lead Biologics  
Antibodies
Biological lead compounds which have a specific amino acid sequence that only interacts with specific substances to cause an immunological response.

Target Products:

  • Humanized Antibody Technology
 
Target Discovery/Validation  
Services
Drug discovery services that discover and validate drug targets for the development of novel biopharmaceutical drugs.

Buyer Products:

  • BioDuro LLC
 
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting  
Industry-Specific IT Services  
Healthcare
IT solutions tailored and marketed for the healthcare industry.

Buyer Products:

  • CSS Informatics Consulting Services
  • Clinical Trial Software Consulting
 
Software  
Industry-Specific  
Healthcare/Pharma  
Drug Development  
Clinical Trials Management
Software designed to manage the information and processes relating to clinical trials.

Buyer Products:

  • CSS Informatics TableTrans
  • PPD GlobalView Electronic Data Capture (EDC)
  • E2B ICSR Browser
  • CSS Informatics PDD Patient Profiles
  • CSS Informatics eLoader
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Covance Inc. n/a 2,734.090 19.75 16.77 1.26 1.31 2.09
PAREXEL International Corporation n/a 1,146.826 28.17 17.66 0.80 0.84 5.37
ICON plc (ADR) n/a 1,003.585 24.76 30.35 1.07 1.06 1.44
WuXi PharmaTech (Cayman) Inc. (ADR) n/a 829.852 8.38 11.27 2.26 2.05 2.02
Nordion Inc(USA) n/a 571.739 40.41 12.50 2.11 1.99 1.72
Kendle International LLC n/a 228.051 n/a n/a 0.53 n/a n/a
Cross Country Healthcare, Inc. n/a 157.685 n/a 31.31 0.32 0.31 4.69
Bioanalytical Systems, Inc. n/a 10.576 n/a 5.80 0.33 0.28 0.71
Quintiles Transnational Corp. n/a n/a n/a n/a n/a n/a n/a
Target
  Crucell N.V. (ADR) n/a 2,452.264 n/a n/a 3.68 n/a 2.80
Sangamo Biosciences, Inc. n/a 156.342 n/a -4.21 15.24 17.54 1.86
Dyax Corp. n/a 127.385 n/a -4.06 2.57 2.50 n/a
Soligenix, Inc. n/a 6.845 n/a n/a 0.94 n/a 1.09

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Target
  Roche Holding Ltd. (ADR) n/a 137,699.517 14.29 10.34 2.73 2.98 n/a

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Chemokine Therapeutics Corp. n/a 0.070 n/a n/a n/a n/a n/a
Government - United States n/a n/a n/a n/a n/a n/a n/a
Target
  Roche Holding Ltd. (ADR) 86.00% 137,699.517 14.29 10.34 2.73 2.98 n/a
Elan Corporation, plc (ADR) 10.00% 6,313.016 9.83 215.80 4.92 4.95 10.03
Pfizer Inc. n/a 155,184.286 13.77 8.82 2.27 2.33 n/a
Bristol Myers Squibb Co. n/a 55,894.708 16.79 14.37 2.67 2.64 7.15
Biogen Idec Inc. n/a 27,465.886 23.33 19.91 5.56 5.64 8.02
Alexion Pharmaceuticals, Inc. n/a 12,359.826 79.97 64.13 17.36 16.46 14.00
EKR Therapeutics, Inc. n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Elan Corporation, plc (ADR) n/a 6,313.016 9.83 215.80 4.92 4.95 10.03
Buyer
  Microsoft Corporation n/a 211,299.869 9.04 9.16 2.97 2.82 4.61
Merck & Co., Inc. n/a 109,306.678 26.11 9.51 2.28 2.28 15.42
Elan Corporation, plc (ADR) n/a 6,313.016 9.83 215.80 4.92 4.95 10.03
Furiex Pharmaceuticals, Inc. n/a 170.947 n/a -3.34 61.18 33.44 5.68
Galectin Therapeutics Inc n/a 56.321 n/a -4.88 n/a 6.42 7.77
VirtualScopics, Inc. n/a 28.726 n/a 95.00 2.01 n/a 4.32
Chemokine Therapeutics Corp. n/a 0.070 n/a n/a n/a n/a n/a
Bend Research, Inc. n/a n/a n/a n/a n/a n/a n/a
Peking Union Lawke Biomedical Development Limited (PUL) n/a n/a n/a n/a n/a n/a n/a
Target
  Pfizer Inc. n/a 155,184.286 13.77 8.82 2.27 2.33 n/a
Roche Holding Ltd. (ADR) n/a 137,699.517 14.29 10.34 2.73 2.98 n/a
Bristol Myers Squibb Co. n/a 55,894.708 16.79 14.37 2.67 2.64 7.15
Biogen Idec Inc. n/a 27,465.886 23.33 19.91 5.56 5.64 8.02
Alexion Pharmaceuticals, Inc. n/a 12,359.826 79.97 64.13 17.36 16.46 14.00
Elan Corporation, plc (ADR) n/a 6,313.016 9.83 215.80 4.92 4.95 10.03

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 1,594.8 365.4 1,960.2
Other Revenue n/a n/a n/a
Total Revenue 1,594.8 365.4 1,960.2
Cost of Revenue 850.1 n/a 850.1
SG&A Expense 433.6 25.5 459.1
Depreciation & Amortization 65.8 0.1 65.8
Research & Development 7.6 n/a 7.6
Interest Expense n/a n/a n/a
Other Operating Expense n/a n/a n/a
Unusual Expense (Income) 4.2 92.2 96.5
Total Expenses 1,361.2 117.8 1,479.0
Operating Income 233.6 247.6 481.2
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng 19.5 -28.0 -8.5
Other, Net 2.1 n/a 2.1
Income Before Taxes 239.5 210.7 450.2
Income Taxes 73.6 74.7 148.3
Income After Taxes 165.9 136.0 301.9
Minority Interest (IS) 1.5 n/a 1.5
Net Income - Excl. Xord. Items 167.4 136.0 303.4
Net Income - Incl. Xord. Items 167.4 136.0 303.4
Income Avail. to Common 167.4 136.0 303.4
Share Items
Basic Avg. Shares Outstanding 113.9 139.7 253.6
Basic EPS - Excl. Xord. Items 1.45 0.97 1.20
Basic EPS - Incl. Xord. Items 1.45 0.97 1.20
Full Dilution Adjustment n/a 0.8 0.8
Fully Diluted Shares Outstanding 115.2 167.0 282.2
F.D. EPS - Excl. Xord. Items 1.43 0.72 1.08
F.D. EPS - Incl. Xord. Items 1.43 0.72 1.08
Dividends Per Common Share 0.60 0.75 1.35
Balance Sheet
Assets
Cash and Equivalents 416.7 157.1 573.9
ST Investments 63.6 37.8 101.4
Accounts Receivable 522.5 0.2 522.6
Inventory n/a n/a n/a
Prepayments and Advances 25.7 6.1 31.8
Other Current Assets 74.6 17.2 91.8
Current Assets 1,103.1 218.2 1,321.3
PPE 826.1 n/a 826.1
Accum D&A -421.7 n/a -421.7
PPE, Net 404.4 0.0 404.4
Goodwill & Intangibles 321.1 n/a 321.1
Long Term Investments 77.6 30.4 107.9
Other Assets n/a n/a n/a
Other LT Assets 44.8 21.9 66.7
Total Assets 1,950.9 270.5 2,221.5
Liabilities
Accounts Payable 37.7 0.3 38.0
Payable/Accrued n/a n/a n/a
Accrued Expenses 204.9 33.3 238.2
ST Debt n/a n/a n/a
Curr Port of LTD & Cap Lease Oblg n/a 115.3 115.3
Other (Current) Liabilities 408.6 24.7 433.3
Current Liab. 651.3 173.6 824.8
LT Debt n/a 340.2 340.2
Total LT Debt n/a 340.2 340.2
Minority Interest (BS) 9.4 n/a 9.4
Deferred Taxes 28.8 n/a 28.8
Other LT Liab. 70.2 n/a 70.2
Total Liabilities 759.7 513.8 1,273.5
Shareholders Equity
Common Stock 5.7 1.4 7.1
Additional Paid in Capital 619.8 -161.9 457.9
Retained Earnings 583.4 -81.0 502.4
Unrealized Gain (Loss) -7.9 n/a -7.9
Other Equity -17.6 -1.8 -19.4
Total Equity 1,191.3 -243.2 948.0
Total Liab. & Equity 1,950.9 270.5 2,221.5
Shares Outstanding 113.7 139.7 253.4
Cash Flow
Operating Cash Flow
CF Net Income 165.9 136.0 301.9
CF Depreciation 66.9 1.2 68.0
CF Deferred Taxes 3.5 25.1 28.6
Other Non-Cash Items 31.9 9.7 41.5
Change in Working Capital -39.0 -17.3 -56.3
Total Cash From Operating Activities 229.1 154.6 383.7
Investing Cash Flow (not calculated)
Capital Expenditures -82.9 0.0 -82.9
Other Investing Cash Flows 74.3 -42.6 31.6
Total Cash From Investing Activities -8.7 -42.6 -51.3
Financing Cash Flow (not calculated)
Dividends Paid -70.7 -133.1 -203.7
Purchase Or Sale of Stock -164.9 n/a -164.9
Purchase and Retirement of Debt n/a 337.5 337.5
Other Financing Cash Flow 1.3 -107.2 -105.8
Total Cash From Financing Activities -234.2 -155.3 -389.5
Exchange Rate Effects -10.0 n/a -10.0
Net Change in Cash -23.7 -43.4 -67.1
Cash Taxes Paid 40.4 135.0 175.4
Cash Interest Paid 0.1 60.6 60.7