Summary

Other Scenarios:

Buyer: Pfizer Inc (PFE) Last Price: 22.57 Market Cap.: 176.09B
Target: Roche Holding AG (RHHBY) Last Price: 40.32 Market Cap.: 139.11B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
Consumer   890
Consumer Products and Services   341
Healthcare 732
Biopharmaceuticals 334
Healthcare Services   122
Medical Devices 177
Nutritional Health   26
Outsourced Biomedical Services 39
Scientific Products   23
Veterinary Products and Services   8
Technology   806
Information Technology (IT) Services   105
Software   246

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business

Buyer (Total: 446)
  • Vistaril (Hydroxyzine Pamoate)
  • Alavert Disintegrating Tablets (Loratadine)
  • Phenergan (Promethazine)
  • Accupril (Quinapril Hydrochloride)
Target (Total: 301)
  • Xolair (Omalizumab)
  • Dilatrend (Carvedilol)
  • Demadex (Toresmide)
  • TNKase/Metalyse (Tenecteplase)
Buyer
  • ChapStick
  • CorVue (Binodenoson Injection)
  • Parke-Davis/ e.p.t.
  • Pharmacia CAP System
Target
  • Quantitative Diagnostics Laboratories, Inc. (QDL)
  • Verum Diagnostica GmbH
  • Roche Diagnostics - Roche/Hitachi 902/912
  • Roche Diagnostics - Cobas 8000 Modular Analyser Series

Business Relationship Summary:

Top Key Suppliers

Top Key Customers

Buyer (Total: 70)
  • Protalix BioTherapeutics Inc (PLX)
  • pSivida Corp (PSDV)
  • Medivation Inc (MDVN)
  • PDI Inc (PDII)
Target (Total: 64)
  • Synageva BioPharma Corp (GEVA)
  • PDL Biopharma Inc (PDLI)
  • Seattle Genetics Inc (SGEN)
  • Alnylam Pharmaceuticals Inc (ALNY)
Buyer (Total: 26)
  • McKesson Corp (MCK)
  • Cardinal Health Inc (CAH)
  • AmerisourceBergen Corp (ABC)
  • Astrazeneca PLC (AZN)
Target (Total: 27)
  • Novartis SA (NVS)
  • Regeneron Pharmaceuticals Inc (REGN)
  • Gen-Probe Inc (GPRO)
  • Ironwood Pharmaceuticals Inc (IRWD)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 110,600 80,653
Revenue Per Employee 615,937.1 664,913.5
Total Revenue 15,405.0 20,860.0
Total Expenses 12,852.0 14,866.0
Other Revenue n/a n/a
Cost of Revenue 2,895.0 5,844.0
SG&A Expense 4,108.0 5,090.0
Research & Development 1,765.0 4,200.0
Other Operating Expense 109.0 -786.0
Operating Income 2,553.0 5,994.0
Unusual Income 2,246.0 507.0
LT Debt to Capital 28.72 65.98
Fwd P/E 10.21 10.09
Fwd P/Rev 2.93 2.93
Book Value 83,213.0 12,095.0
Curr Portion of LTD/Cap Lease n/a 3,394.0

Individual Company Summary

Focused

Buyer

Focused (): Healthcare > Biopharmaceuticals

Target

Focused (): Healthcare > Biopharmaceuticals

Business Description

Buyer

Pfizer Inc. (Pfizer) is a research-based, global biopharmaceutical company. The Company operates in two segments: Biopharmaceutical and Diversified. Biopharmaceutical includes the Primary Care, Specialty Care, Established Products, Emerging Markets and Oncology customer-focused units, which includes products that prevent and treat cardiovascular and metabolic diseases, central nervous system disorders, arthritis and pain, respiratory diseases, urogenital conditions, cancer, eye disease and endocrine disorders, among others. Diversified includes Animal Health products; Consumer Healthcare products , such as pain management therapies, cough/cold/allergy remedies, dietary supplements, hemorrhoidal care and other personal care items; Nutrition products such as infant and toddler formula products, and Capsugel. On January 31, 2011, it acquired approximately 92.5% of King?s common stock. In August 2011, it sold its Capsugel business to an affiliate of Kohlberg Kravis Roberts & Co. L.P.

Target

Roche Holding AG is a Switzerland-based pharmaceuticals and diagnostics company. It belongs to the Roche Group that operates through subsidiaries and associated companies around the world. It discovers, develops and provides diagnostic and therapeutic products and services from early detection and prevention of diseases to diagnosis, treatment and treatment monitoring. Roche has two divisions: Pharmaceuticals and Diagnostics. Pharmaceuticals are divided into three sub-divisions: Roche Pharmaceuticals, Genentech and Chugai. It operates in the United States, Western Europe, Japan, CEMAI (Central and Eastern Europe, Middle East, Africa, Central Asia, Indian Subcontinent), Latin America, Asia-Pacific and Other regions. Diagnostics include five sub-divisions: Applied Science, Diabetes Care, Molecular Diagnostics, Tissue Diagnosis and Professional Diagnostics. It is structured into five segments: North America; Asia-Pacific; EMEA (Europe, Middle East and Africa); Latin America and Japan.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 78.17 80.52
Operating Margin % 19.03 52.74
Quick Ratio 1.41 1.3
Current Ratio 2.02 1.74
Coverage Ratio n/a n/a
Total Assets 185,683.0 61,576.0
Return on Equity % 63.08 354.76
Return on Assets % 28.28 69.68
Cash+ ST Inv. Per Share 3.16 13.29
Total Debt 39,069.0 26,853.0
Total Debt to Equity % 46.93 222.02
Total Debt to Tangible Equity % n/a n/a
Debt to Asset % 21.04 43.61

Product Summary

Sector Buyer Target
Consumer  
Consumer Products and Services  
Personal Care and Cleaning Products
Companies engaged in the manufacturing of personal care products, such as cosmetics, fragrances, skin lotion, sanitary/personal care paper (tissues), shampoo and other toiletries; and household cleaning products, such as window/surface cleaner, and table polish.
 
Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes therapeutics that treat female genital disorders, pregnancy, and childbirth.
 
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes therapeutics that treat and manage weight disorders.
Wound Management
The Wound Management Subsector includes therapeutics that treat cuts, abrasions, and burns from trauma or diseases.
Healthcare Services  
Patient Care
The Patient Care Subsector is comprised of companies that provide services to patients for the diagnosis, treatment, and/or prevention of diseases and injuries.
 
Medical Devices
Cardiology
The Cardiology Subsector includes medical devices that diagnose, monitor, and treat diseases affecting the heart and proximal blood vessels. Common devices include vital sign monitors, cardiac defibrillators, pacemakers, and other surgical equipment.
 
Clinical Diagnostics
The Clinical Diagnostics Subsector includes medical devices that analyze human body specimens within a medical setting. These devices, including equipment, biological and chemical reagents are primarily used for the diagnosis of diseases.
Drug Delivery
The Drug Delivery Subsector includes medical devices that facilitate the delivery of medications through different anatomical entryways, including blood vessels, skin, the mouth, and the lungs. Common devices in this sector include vascular access catheters, needles, implants, and inhalers.

Buyer Products:

  • Pfizer Animal Health - Synbiotics Corporation
General Surgery
The General Surgery Subsector includes medical devices that perform general, non-specialty surgeries; these devices are often general in scope and are used in procedures involving various parts of the body.
 
Orthopedics
The Orthopedics Subsector includes medical devices that diagnose and treat musculoskeletal diseases involving muscles, bones and joints.
 
Radiology
The Radiology Subsector includes medical devices that generate images of internal physiology.
 
Nutritional Health  
Dietary/Naturopathic Supplements
The Dietary/Naturopathic Subsector includes nutritional biochemicals and nutrients derived from natural sources that are intended to support health.
 
Outsourced Biomedical Services
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Target Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
 
Bioanalytical Services
The Bioanalytical Services Subsector includes outsourced services that utilize bioanalytical instruments to analyze biological samples.
 
Development/Manufacturing Services
The Development/Manufacturing Services Subsector includes companies that provide research, development, manufacturing, sales and marketing to biopharmaceutical and medical device companies.
 
Drug Discovery Services
The Drug Discovery Services Subsector includes companies that provide biopharmaceutical companies with novel biological targets and drug leads.
 
Scientific Products  
Analytical Instruments
The Analytical Instruments Subsector includes scientific products that determine the quantitative and qualitative nature of chemical and biochemical samples.
 
Bioanalytical Instruments
The Bioanalytical Subsector includes scientific products, devices, apparatuses, and consumables used to determine the quantitative and qualitative nature of a biological samples.
 
Veterinary Products and Services  
Veterinary Diagnostics
The Veterinary Diagnostics Subsector includes companies that manufacture veterinary diagnostics for the detection and monitoring of veterinary diseases.

Buyer Products:

  • Pfizer Animal Health - Synbiotics Corporation
 
Veterinary Pharmaceuticals
The Veterinary Pharmaceuticals Subsector includes companies that manufacture veterinary pharmaceuticals and vaccines for the prevention and treatment of veterinary diseases.

Buyer Products:

  • Synbiotics Corporation
  • Pfizer Animal Health
  • Embrex, Inc.
  • Fort Dodge Animal Health
 
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting
Information technology related to consulting services designed to improve a client company's operating efficiency, and business capabilities through the expert application of information technology resources and best practices. These services can be delivered on a project-by-project basis, or via an on-going relationship.
 
Software  
Industry-Specific
Software that has functionality specific to a vertical industry.
 

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
Consumer  
Consumer Products and Services  
Personal Care and Cleaning Products  
Skin Care
Companies engaged in the manufacturing of skin care products, such as suntan lotion, skin lotion, sanitizer, shaving cream, and moisturizer. Also includes manufacturers of non-electrical shaving equipment.

Buyer Products:

  • ChapStick
 
Healthcare
Biopharmaceuticals
Allergies
Dermatology  
Antihistamines
Products that inhibit inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Vistaril (Hydroxyzine Pamoate)
  • Alavert Disintegrating Tablets (Loratadine)
  • Phenergan (Promethazine)
 
Ophthalmology  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Phenergan (Promethazine)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for treatment of allergic reactions in early stages of clinical research where human subject is involved.

Buyer Products:

  • Accupril (Quinapril Hydrochloride)

Target Products:

  • Xolair (Omalizumab)
Systemic  
Anaphylactic Shock  
Alpha Adrenergic Receptor Agonists/Beta Adrenergic Receptor Agonists
Therapeutics that treat allergic shock by stimulating alpha and beta adrenergic receptors.

Buyer Products:

  • Adrenalin Chloride Solution (Epinephrine)
  • Meridian Medical Technologies - EpiPen Series (Epinephrine) [Dey L.P.]
 
Upper Respiratory
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Alavert Disintegrating Tablets (Loratadine)
  • Phenergan (Promethazine)
 
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and relieve or prevent coughs.

Buyer Products:

  • Dimetapp (Brompheniramine Maleate/Phenylpropanolamine Hydrocholride)
 
Monoclonal Antibodies
Therapeutics that treat allergic reactions by specifically binding and inhibiting inflammatory substances.

Target Products:

  • Xolair (Omalizumab)
 
Cardiovascular System
Heart Disorders
Angina  
Anticoagulating Agents  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Fragmin (Dalteparin Sodium)
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat chest pains by inhibiting stimulation of beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Corgard (Nadolol)
  • Inderal LA Long-Acting Capsules (Propranolol Hydrochloride)
 
Calcium Channel Blocking Agents
Therapeutics that treat chest pains by preventing the entry of calcium into heart muscle cells.

Buyer Products:

  • Procardia XL (Nifedipine)
  • Procardia (Nifedipine)
  • Norvasc (Amlodipine Besylate)
  • Covera HS (Verapamil Hydrochloride)
  • Calan/Calan SR (Verapamil Hydrochloride)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that reduce the risk of chest pains by preventing the synthesis of cholesterol.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Vasodilatory Agents
Therapeutics that treat chest pains by acting on blood vessels to lower blood pressure.

Buyer Products:

  • Nitrostat (Nitroglycerin Sublingual)
 
Arrhythmia  
Adenosine A1 Receptor Agonists
Therapeutics that treat abnormal rhythm of the heart beat by selectively stimulating the A1 adenosine receptor, slowing the speed of AV nodal conduction

Buyer Products:

  • Adenocard (Adenosine)
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat abnormal rhythm of the heart beat by inhibiting the stimulation of beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Inderal LA Long-Acting Capsules (Propranolol Hydrochloride)
 
Calcium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of calcium into heart muscle cells.

Buyer Products:

  • Calan/Calan SR (Verapamil Hydrochloride)
 
Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of potassium into heart muscle cells.

Buyer Products:

  • Tikosyn (Dofetilide)
 
Sodium Channel Agonists
Therapeutics that treat abnormal rhythm of the heart by increasing the entry of sodium ions into the heart muscle to extending the time an electrical impulse travels across a neuron.

Buyer Products:

  • Corvert (Ibutilide Fumarate)
 
Sodium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium into heart muscle cells.

Buyer Products:

  • Procanbid (Procainamide Hydrochloride)
  • Norpace (Disopyramide Phosphate)
 
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium and potassium into heart muscle cells.

Buyer Products:

  • Cordarone Tablets (Amiodarone Hydrochloride)
  • Cordarone I.V. (Amiodarone Hydrochloride)
 
Heart Failure (HF)
Adjunctive Treatments  
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that assist in the primary treatment of the ineffective pumping of the heart by inhibiting the renin-angiotensin system.

Buyer Products:

  • Accupril (Quinapril Hydrochloride)
 
Vasodilatory Agents
Therapeutics that assist the primary treatment of the ineffective pumping of the heart by dilating blood vessels to lower blood pressure.

Buyer Products:

  • Nitrostat (Nitroglycerin Sublingual)
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat the ineffective pumping of the heart by inhibiting the renin-angiotensin system.

Buyer Products:

  • King Phramaceuticals, Inc. - Altace (Ramipril)
  • Altace (Ramipril)
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat the ineffective pumping of the heart by blocking beta adrenergic receptors of the heart muscle.

Target Products:

  • Dilatrend (Carvedilol)
 
Complications
Edema
Loop Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Demadex (Toresmide)
 
Potassium Sparing Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of water, but not potassium in the urine.

Buyer Products:

  • Aldactone (Spironolactone)
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Aldactazide (Spironolactone/Hydrochlorothiazide)
 
Selective Aldosterone Receptor Antagonists (SARA)
Therapeutics that selectively block the action of aldosterone, a chemical implicated in causing cardiovascular disease.

Buyer Products:

  • Inspra (Eplerenone)
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of sodium, potassium ions, and water in urine.

Buyer Products:

  • Thalitone (Chlorthalidone)
  • Renese (Polythiazide)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the ineffective pumping of the heart by preventing the synthesis of cholesterol.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Myocardial Infarction (MI)
Adjunctive Treatment  
Vasodilatory Agents
Therapeutics that treat high blood pressure by causing relaxation of the blood vessels.

Buyer Products:

  • Nitrostat (Nitroglycerin Sublingual)
 
Anticoagulating Agents  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Argatroban
  • Fragmin (Dalteparin Sodium)
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Inderal LA Long-Acting Capsules (Propranolol Hydrochloride)

Target Products:

  • Dilatrend (Carvedilol)
Calcium Channel Blocking Agents
Therapeutics that treat irreversible damage to the heart muscle by blocking the influx of calcium ions into heart muscle cells.

Buyer Products:

  • Norvasc (Amlodipine Besylate)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat irreversible damage to the heart muscle by preventing the synthesis of cholesterol.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Thrombolytic Agents
Therapeutics that treat the ineffective pumping of the heart by dissolving blood clots in blood vessels.

Target Products:

  • TNKase/Metalyse (Tenecteplase)
  • Activase (Alteplase)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • TBC3711 (Endothelin Receptor Antagonist)
  • PF-489791
  • Terguride (5-HT2A/5-HT2B Recenptor Antagonist)
  • PF-3049423
  • Accuretic (Quinapril Hydrochloride/Hydrochlorothiazide)
  • Tafamidis Meglumine
  • PF-3185043

Target Products:

  • RG1512 (P-Selectin Monoclonal Antibody)
  • RG7418 (Anti-oxLDL Antibody)
  • BO-653 (Antioxidant)
  • AXV034343 (Endothelin A Receptor Antagonist)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • ILS-920
  • GAP-134
  • SKS-927
 
Vascular Disorders
Coronary Artery Disease (CAD)  
Calcium Channel Blocking Agents
Therapeutics that treat the narrowing or hardening of the coronary arteries of the heart muscle by blocking the influx of calcium ions into heart muscle cells.

Buyer Products:

  • Norvasc (Amlodipine Besylate)
 
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Factor Xa Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Eliquis (Apixaban)
 
Thrombin Inhibitors
Therapeutics that prevent or treat clots in blood vessels by preventing blood clots from forming.

Buyer Products:

  • Argatroban
  • Fragmin (Dalteparin Sodium)
 
Hypertension
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that treat high blood pressure by blocking alpha adrenergic receptors of the heart muscle.

Buyer Products:

  • Minipress (Prazosin Hydrochloride)
  • Cardura (Doxazosin Mesylate)
 
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by inhibiting stimulation of alpha adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • Minizide (Prazosin Hydrochloride/Polythiazide)
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat high blood pressure by inhibiting the renin-angiotensin system.

Buyer Products:

  • King Phramaceuticals, Inc. - Altace (Ramipril)
  • Accupril (Quinapril Hydrochloride)
  • Altace (Ramipril)
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by inhibiting the renin-angiotensin system and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • Altace (Ramipril)/Hydrochlorothiazide Combination Product
  • Accuretic (Quinapril Hydrochloride/Hydrochlorothiazide)
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Corgard (Nadolol)
  • Inderal LA Long-Acting Capsules (Propranolol Hydrochloride)
 
Beta Receptor Blocking Agents (Beta Blockers)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • Inderide (Propranolol Hydrochloride And Hydrochlorothiazide)
  • Corzide (Nadolol/Bendroflumethiazide)
 
Calcium Channel Blocking Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • Procardia XL (Nifedipine)
  • Norvasc (Amlodipine Besylate)
  • Covera HS (Verapamil Hydrochloride)
  • Calan/Calan SR (Verapamil Hydrochloride)
 
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Caduet (Amlodipine/Atorvastatin)
 
Loop Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Demadex (Toresmide)
 
Potassium Sparing Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of water, but not potassium in the urine.

Buyer Products:

  • Aldactone (Spironolactone)
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Aldactazide (Spironolactone/Hydrochlorothiazide)
 
Selective Aldosterone Receptor Antagonists (SARA)
Therapeutics that selectively block the action of aldosterone, a chemical implicated in causing hypertension.

Buyer Products:

  • Inspra (Eplerenone)
 
Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium ions, and water in urine.

Buyer Products:

  • Thalitone (Chlorthalidone)
  • Renese (Polythiazide)
 
Vasodilatory Agents
Therapeutics that treat high blood pressure by causing relaxation of the blood vessels.

Buyer Products:

  • Loniten (Minoxidil)
  • Nitrostat (Nitroglycerin Sublingual)
 
Primary Pulmonary Hypertension  
Phosphodiesterase Type 5 Inhibitors (PDE-5 Inhibitors)
Therapeutics that treat hypertension by increasing level of nitric oxide that help to dilate blood vessels.

Buyer Products:

  • Revatio (Sildenafil Citrate)
 
Stroke
Anticoagulating Agents (Anticoagulants)  
Factor Xa Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Eliquis (Apixaban)
 
Calcium Channel Blocking Agents
Therapeutics that prevent strokes by blocking the influx of calcium ions into vascular cells.

Buyer Products:

  • Norvasc (Amlodipine Besylate)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat damage to nerve cells of the brain by preventing the synthesis of cholesterol.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Thrombolytic Agents
Therapeutics that prevent or treat damage to nerve cells of the brain by dissolving blood clots in blood vessels.

Target Products:

  • Activase (Alteplase)
 
Thromboembolism
Anticoagulating Agents (Anticoagulants)  
Factor Xa Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Eliquis (Apixaban)
 
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Fragmin (Dalteparin Sodium)
 
Thrombolytic Agents
Therapeutics that treat obstructions of blood vessels by dissolving blood clots.

Target Products:

  • Activase (Alteplase)
  • TNKase/Metalyse (Tenecteplase)
 
Dermatology
Acne  
Vulgaris  
Antibacterial Agents  
Lincosamides
Therapeutics that treat acne vulgaris caused by bacterial infection by inhibiting bacterial protein synthesis.

Buyer Products:

  • Cleocin T (Clindamycin Phosphate)
 
Lesion/Scaling Disorders
Chronic Urticaria  
Monoclonal Antibodies
Therapeutics that treat chronic urticaria by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Xolair (Omalizumab)
 
Dermatoses  
Steroidal Anti-Inflammatory Drugs (SAID)/Antibacterial Agents (Antibiotic)
Therapeutics that counteract or suppress inflammation by inhibiting the accumulation of inflammatory cells like leucocytes and macrophages at the inflammation site, as well as prevent the growth of bacteria.

Buyer Products:

  • Cortisporin (Neomycin/Polymyxin B Sulfates/Hydrocortisone Acetate) Cream/Ointment
 
Pruritus  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Vistaril (Hydroxyzine Pamoate)
 
Psoriasis  
Janus-Associated Kinase (JAK) Inhibitors
Therapeutics that treat psoriasis by selectively inhibiting the production of a variety of inflammatory causing cytokines.

Buyer Products:

  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)
 
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat psoriasis by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skin disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PF-5212367/ILV-094
  • PF-5212368
  • PF-05230895/SBI-087 (SMIP CD20 Modulator)
  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)

Target Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
  • BAL2299 (Nuclear Receptor Modulator)
Digestive System
Gastrointestinal Tract Disorders
Gastroduodenal Disorders  
Peptic Ulcers  
Gastric  
Antisecretory Agents
Therapeutics that treat peptic ulcers by preventing the secretion of acid.

Buyer Products:

  • Cytotec (Misoprostol)
 
Zollinger-Ellison Syndrome  
Proton Pump Inhibitors
Therapeutics that treat ulcers by inhibiting the membrane protein involved in the final steps of triggering acid release into the stomach.

Buyer Products:

  • Protonix Delayed-Release Tablets (Pantoprazole Sodium)
  • Protonix I.V. (Pantoprazole Sodium)
  • Protonix Delayed-Release Oral Suspension (Pantoprazole Sodium Granules)
 
Gastroesophageal Disorders
Acid Indigestion/Heartburn  
Proton Pump Inhibitors
Therapeutics that treat heartburn by inhibiting the action of the membrane protein involved in the final steps of triggering acid release into the stomach.

Buyer Products:

  • Protonix Delayed-Release Tablets (Pantoprazole Sodium)
 
Erosive Esophagitis  
Proton Pump Inhibitors
Therapeutics that treat Erosive Esophagus by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Protonix Delayed-Release Tablets (Pantoprazole Sodium)
  • Protonix I.V. (Pantoprazole Sodium)
  • Protonix Delayed-Release Oral Suspension (Pantoprazole Sodium Granules)
 
Gastroesophageal Reflux Disease (GERD)  
Dopamine Receptor Blocking Agents
Therapeutics that treat Gastroesophageal Reflux Disease (GERD) by blocking dopamine receptor and stimulating gastrointestinal movement without stimulating secretions from the pancreas, stomach or gall bladder.

Buyer Products:

  • Reglan (Metoclopramide Hydrochloride)
 
Proton Pump Inhibitors
Therapeutics that treat Gastroesophageal Reflux Disease by inhibiting the membrane protein involved in the final steps of triggering acid release into the stomach.

Buyer Products:

  • Protonix Delayed-Release Tablets (Pantoprazole Sodium)
  • Protonix I.V. (Pantoprazole Sodium)
  • Protonix Delayed-Release Oral Suspension (Pantoprazole Sodium Granules)
 
Gastroparesis  
Dopamine Receptor Blocking Agents
Therapeutics that treat gastroparesis by blocking the action of dopamine.

Buyer Products:

  • Reglan (Metoclopramide Hydrochloride)
 
Nausea/Vomiting
Antiemetic Agents
Therapeutics that treat nausea or vomiting by acting locally on the hyperactive gastrointestinal wall.

Buyer Products:

  • Tigan (Trimethobenzamide Hydrochloride)
  • Phenergan (Promethazine)
 
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Vistaril (Hydroxyzine Hydrochloride)
 
Dopamine Receptor Blocking Agents
Therapeutics that treat or prevent nausea and vomiting by blocking the action of dopamine.

Buyer Products:

  • Reglan (Metoclopramide Hydrochloride)
 
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Target Products:

  • Kytril (Granisetron Hydrochloride)
 
Intestinal Disorders  
Constipation  
Chronic  
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Buyer Products:

  • FiberCon (Calcium Polycarbophil)
 
Irregular Bowel Movements  
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Buyer Products:

  • FiberCon (Calcium Polycarbophil)
 
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Relistor (Subcutaneous Methylnaltrexone Bromide)
 
Diarrhea  
Antiperistaltic Agents
Therapeutics that treat diarrhea by inhibiting the wavelike motion of the digestive tract.

Buyer Products:

  • Lomotil (Diphenoxylate Hydrochloride/Atropine Sulfate)
 
Familial Adenomatous Polyposis (FAP)  
Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat colon polyps by inducing suicide in the abnormal cells.

Buyer Products:

  • Celebrex (Celecoxib)
 
Inflammatory Bowel Disease (IBD)  
Ulcerative Colitis  
Cyclooxygenase Inhibitors (COX Inhibitors)/Lipoxygenase Inhibitors
Therapeutics that treat ulcerative colitis by inhibiting the actions of the two enzymes, cyclooxygenase and lipoxygenase.

Buyer Products:

  • Dipentum (Olsalazine Sodium)
  • Azulfidine/Azulfidine EN-Tabs (Sulfasalazine)
 
Intestinal Intubation  
Dopamine Receptor Blocking Agents
Therapeutics that cause bowel evacuation prior to intubation by blocking the action of dopamine.

Buyer Products:

  • Reglan (Metoclopramide Hydrochloride)
 
Rectal Disorders  
Hemorrhoids  
Alpha Adrenergic Receptor Agonists
Therapeutics that treat hemorrhoids by stimulating the alpha adrenergic receptors.

Buyer Products:

  • Preparation H (Phenylephrine Hydrochloride)
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat or suppress inflammation by preventing the accumulation of inflammatory cells like leucocytes and macrophages to the inflammation sites.

Buyer Products:

  • Preparation H Hydrocortisone (Hydrocortisone)
 
Liver Disorders
Cirrhosis
Complications
Edema
Loop Diuretic Agents
Therapeutics that prevent edema by excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Demadex (Toresmide)
 
Potassium Sparing Diuretic Agents
Therapeutics that prevent edema by excretion of water, but not potassium, in the urine.

Buyer Products:

  • Aldactone (Spironolactone)
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Buyer Products:

  • Aldactazide (Spironolactone/Hydrochlorothiazide)
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium, potassium ions, and water in urine.

Buyer Products:

  • Thalitone (Chlorthalidone)
  • Renese (Polythiazide)
 
Hepatitis  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
 
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  • Pegasys (Pegylated Interferon Alfa-2a)
 
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections by preventing viral replication, stimulating the immune system to also fight the virus, and inhibits replication of viral DNA by incorporating themselves into growing viral DNA stands.

Target Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • MultiStem IBD Program (Adult Human Stem Cells)
  • Relistor (Subcutaneous Methylnaltrexone Bromide)
  • Oral MNTX (Methylnaltrexone)
  • PF-2391677
  • PF-868554 (HCV Protease Inhibitor)

Target Products:

  • R1270 (Levovirin)
  • RG7413 (Anti-Beta 7 Monoclonal Antibody)
  • Serine Palmitoyl Transferase Inhibitor
  • RG7432 (Nucleoside Polymerase Inhibitor)
  • RG7348 (Nucleoside Analogue)
  • R1479 (Polymerase Inhibitor)
  • Mitemcinal Fumarate/GM -611 (Motilin Agonist)
  • Mericitibine/Formerly RG7128/RO5024048 (Cytidine Nucleoside Analog Prodrug)
Endocrinology/Metabolism
Adrenal Gland Disorders  
Primary Aldosteronism  
Potassium Sparing Diuretic Agents
Therapeutics that treat aldosteronism by excretion of water, but not potassium, in the urine.

Buyer Products:

  • Aldactone (Spironolactone)
 
Diabetes
Induced Complications  
Diabetic Neuropathy  
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat diabetic neuropathy by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Pristiq (Desvenlafaxine Succinate Extended Release)
 
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes
Alpha-Glucosidase Inhibitors
Therapeutics that treat diabetes by stopping the enzyme that releases glucose from larger molecules.

Buyer Products:

  • Glyset (Miglitol)
 
Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 Receptor Agonists)
Therapeutics that treat non-insulin dependent diabetes by stimulating the Glucagon-Like Peptide (GLP) receptor. GLP regulates gastric emptying, insulin secretion, food intake, and glucagon secretion.

Target Products:

  • Taspoglutide
 
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin.

Buyer Products:

  • Glucotrol XL (Glipizide)
  • Glucotrol (Glipizide)
  • Diabinese (Chlorpropamide)
  • Tolinase (Tolazamide)
  • Micronase (Glyburide)
  • Glynase (Glyburide)
 
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Products that sensitize organs to insulin.

Target Products:

  • RG1439/Aleglitazar (Dual PPAR Agonist)
 
General Hormone Treatments  
Cortisols
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Buyer Products:

  • Cortef/Solu-Cortef (Hydrocortisone)
 
Estrogens
Therapeutics that treat hormonal disorders by providing estrogen.

Buyer Products:

  • Menest (Esterified Estrogens Tablets)
  • Ogen (Estropipate)
  • Delestrogen (Estradiol Valerate Injection, USP)
 
Prednisolones
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Buyer Products:

  • Solu-Medrol (Methylprednisolone Sodium)
  • Medrol/Depo Medrol (Methylprednisolone)
 
Hyperglycemia  
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that stimulate the secretion of insulin.

Buyer Products:

  • Glucotrol XL (Glipizide)
  • Glucotrol (Glipizide)
 
Intermediary Metabolism Disorders
Gout  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat gouty arthritis by preventing cyclooxygenase activity.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Hypercholesterolemia
Bile Acid Binding Agents
Therapeutics that treat hypercholesterolemia by binding bile acids in the intestine.

Buyer Products:

  • Colestid/Flavored Colestid (Colestipol Hydrochloride)
 
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Caduet (Amlodipine/Atorvastatin)
 
Cholesteryl Ester Transfer Protein Inhibitors (CETP)
Therapeutics that treat high cholesterol by interrupting with the transfer of lipids between lipoproteins.

Buyer Products:

  • Torcetrapib

Target Products:

  • Dalcetrapib/RG1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Hyperlipidemia  
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that treat hypercholesterolemia by reducing the levels of very low-density lipoprotein and increasing levels of high-density lipoproteins.

Buyer Products:

  • Lopid (Gemfibrozil)
 
Lysosomal Storage Diseases  
Gaucher Disease  
Enzyme Replacement Therapy
Therapeutics that treat Gaucher's Disease by providing the missing enzymes that contributes to the disease symptoms.

Buyer Products:

  • Elelyso (Taliglucerase alfa)
 
Parathyroid Gland Disorders  
Hyperparathyroidism (HPT)  
Vitamin D Analogs
Therapeutics that act similar to Vitamin D.

Target Products:

  • Rocaltrol (Calcitriol)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Tanezumab
  • Sonedenoson/Formerly MRE0094 (Adenosine A2a Receptor Agonist)
  • PF-4971729
  • PF-4856883/CovX 096
  • PF-5212389

Target Products:

  • RG4929 (11 Beta HSD Inhibitor)
  • RG7201 (SGLT2 Inhibitor)
  • RG7273 (ABCA1 Inducer)
  • RG7426/Genentech BHT-3021
  • RO5095932
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • RO4998452
Pituitary Gland Disorders
Acromegaly  
Growth Hormone Receptor Antagonists
Therapeutics that treat acromegaly by binding to and thus blocking growth hormone receptors. This results in decreased secretion of growth hormone as well as IGF-1, which is responsible for the debilitating effects of the disease.

Buyer Products:

  • Somavert (Pegvisomant)
 
Hyperprolactenemia  
Dopamine Receptor Agonists
Products that stimulate the dopamine receptor.

Buyer Products:

  • Dostinex (Cabergoline)
 
Pituitary Hyperthyroidism (TSH-Induced)  
Thyroid Hormones
Hormones that affect the rate of cell metabolism and blood calcium levels.

Buyer Products:

  • Alpharma Tirosint Capsule (Levothyroxine Sodium)
  • Levoxyl (Levothyroxine Sodium)
 
Severe Short Stature
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Genotropin (Recombinant Somatropin (Human Growth Hormone))

Target Products:

  • Genentech - Nutropin/Nutropin AQ (Recombinant Somatropin (Human Growth Hormone))
Turner`s Syndrome
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Genotropin (Recombinant Somatropin (Human Growth Hormone))

Target Products:

  • Genentech - Nutropin/Nutropin AQ (Recombinant Somatropin (Human Growth Hormone))
Reproductive Disorders  
Amenorrhea  
Progestins
Female sex hormone necessary for the development of the female reproductive system.

Buyer Products:

  • Provera (Medroxyprogesterone Acetate)
 
Hypoestrogenism  
Hormonal Treatments  
Estrogens
Therapeutics that are female sex hormones.

Buyer Products:

  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
  • Premarin (Conjugated Estrogens) Intravenous
 
Hypogonadism  
Female  
Hormonal Treatments  
Estrogens
Therapeutics that are female sex hormones.

Buyer Products:

  • Depo-Estradiol (Estradiol Cypionate Injection)
  • Menest (Esterified Estrogens Tablets)
 
Male  
Androgens
Therapeutics that are male sex hormones.

Buyer Products:

  • Depo-Testosterone (Testosterone)
 
Menopause  
Estrogens
Therapeutics that are female sex hormones.

Buyer Products:

  • Depo-Estradiol (Estradiol Cypionate Injection)
  • Menest (Esterified Estrogens Tablets)
  • Ogen (Estropipate)
  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
  • Premarin Vaginal Cream (Conjugated Estrogens)
 
Estrogens/Progestins
Therapeutics that are mixture of two female sex hormones that are important for the development of the female reproductive system.

Buyer Products:

  • Prempro/Low-Dosage Prempro (Conjugated Estrogens/Medroxyprogesterone Acetate)
 
Estrogens/Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat menopause by a combination of natural female hormone and synthetic female hormone analogues.

Buyer Products:

  • Aprela (Bazedoxifene/Conjugated Estrogen) [Pfizer-Ligand Pharmaceuticals Collaboration]
 
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat vasomotor symptoms associated with menopause by selectively preventing the removal of norepinephrine.

Buyer Products:

  • Pristiq (Desvenlafaxine Succinate Extended Release)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • FXR-450
  • BHS-019
  • PPM-202
  • PPM-201
  • NRI-193

Target Products:

  • MAR701 (Peptide Therapy)
Thyroid Gland Disorders  
Hyperthyroidism  
Thyroid Hormone Synthesis Inhibitors
Therapeutics that stop the production of thyroid hormones.

Buyer Products:

  • Tapazole (Methimazole)
 
Hypothyroidism  
Thyroid Hormones
Therapeutics that treat a deficiency in thyroid activity by supplementing thyroid hormones.

Buyer Products:

  • Alpharma Tirosint Capsule (Levothyroxine Sodium)
  • Levoxyl (Levothyroxine Sodium)
  • Cytomel (Liothyronine Sodium)
 
Hematology
Hemophilia  
Hemophilia A  
Clotting Agents
Therapeutics that aid in blood coagulation.

Buyer Products:

  • ReFacto (Coagulation Factor VIII)
  • Xyntha (Albumin-Free Coagulation Factor VIII)
 
Hemophilia B  
Clotting Agents
Therapeutics that assist in blood coagulation.

Buyer Products:

  • BeneFIX/BeneFIX Reformulation (Coagulation Factor IX)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in early stages of clinical research where human subject is involved.

Target Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
  • RG7273 (ABCA1 Inducer)
 
Red Blood Cell (RBC) Disorders  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues by stimulating red blood cell production.

Target Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
  • Epogin (Epoetin Beta)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • FXR-450
  • Factor VIIa Program
 
Serum Factor Disorders
Hypercholesterolemia
Bile Acid Binding Agents
Therapeutics that treat hypercholesterolemia by binding bile acids in the intestine.

Buyer Products:

  • Colestid/Flavored Colestid (Colestipol Hydrochloride)
 
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Caduet (Amlodipine/Atorvastatin)
 
Cholesteryl Ester Transfer Protein Inhibitors (CETP)
Therapeutics that treat high cholesterol by interrupting with the transfer of lipids between lipoproteins.

Buyer Products:

  • Torcetrapib

Target Products:

  • Dalcetrapib/RG1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Lipitor (Atorvastatin Calcium)
 
Hyperglycemia  
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that stimulate the secretion of insulin.

Buyer Products:

  • Glucotrol XL (Glipizide)
  • Glucotrol (Glipizide)
 
Hyperlipidemia  
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that reduce the levels of very low-density lipoprotein and increasing levels of high-density lipoproteins.

Buyer Products:

  • Lopid (Gemfibrozil)
 
Hypocalcemia  
Vitamin D Analogs
Therapeutics that treat hypocalcemia by increasing serum levels of calcium, as well as helping the bone calcification process.

Target Products:

  • Rocaltrol (Calcitriol)
 
Hypokalemia  
Potassium Sparing Diuretic Agents
Therapeutics that treat hypokalemia by promoting excretion while inhibiting the removal of potassium.

Buyer Products:

  • Aldactone (Spironolactone)
 
Thrombocyte (Platelet) Disorders  
Thrombocytopenia  
Platelet Growth Factors
Therapeutics that promote the growth of particular blood coagulating factors.

Buyer Products:

  • Neumega (Oprelvekin)
 
White Blood Cell (WBC) Disorders  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics that treat neutropenia by inducing the maturation and proliferation of white blood cells.

Target Products:

  • Neutrogin (Granulocyte Colony Stimulating Factor)
 
Immunology
Autoimmune Disorders
Anti-Neutrophil Cytoplasmic Antibodies (ANCA) Associated Vasculitis  
Monoclonal Antibodies
Therapeutics that treat Wegener's Granulomatosis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Rituxan (Rituximab)
 
Arthritis
Psoriatic Arthritis  
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat chronic inflammation of the joints coupled with red, scaly skin patches by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Rheumatoid Arthritis (RA)
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by selectively blocking cyclooxygenase 2 activity.

Buyer Products:

  • Celebrex (Celecoxib)
  • Bextra (Valdecoxib)
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Feldene (Piroxicam)
  • Daypro/Daypro Alta (Oxaprozin)
  • Ansaid (Flurbiprofen)
  • Oruvail (Ketoprofen)
 
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/GI Protective Agents
Therapeutics that treat pain associated with chronic inflammation of the joints, without upsetting the stomach with a non-steroidal compound and an anti-ulcer agent.

Buyer Products:

  • Arthrotec (Diclofenac/Misoprostol)
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Janus-Associated Kinase (JAK) Inhibitors
Therapeutics that treat rheumatoid arthritis by selectively inhibiting the production of a variety of inflammatory causing cytokines.

Buyer Products:

  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)
 
Immunotherapy
Immunosuppressants
Therapeutics that treat chronic inflammation of the joints by inhibiting a full immune response.

Buyer Products:

  • Azulfidine/Azulfidine EN-Tabs (Sulfasalazine)
 
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Actemra (Tocilizumab)
  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
 
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat chronic inflammation of the joints by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Inflammatory Bowel Disease (IBD)  
Ulcerative Colitis  
Cyclooxygenase Inhibitors (COX Inhibitors)/Lipoxygenase Inhibitors
Therapeutics that treat inflammation of the colon and rectum by blocking the action of cyclooxygenase and lipoxygenase.

Buyer Products:

  • Dipentum (Olsalazine Sodium)
  • Azulfidine/Azulfidine EN-Tabs (Sulfasalazine)
 
Lupus Erythematosus  
Systemic (SLE)  
Immunosuppressants
Therapeutics that treat systemic lupus by inhibiting a full immune response.

Target Products:

  • CellCept (Mycophenolate Mofetil)
 
Monoclonal Antibodies
Therapeutics that treat systemic lupus by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Target Products:

  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
 
Multiple Sclerosis (MS)
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that downregulates the antibody response of the immune system.

Buyer Products:

  • Rebif (Recombinant Interferon Beta-1a)
 
Monoclonal Antibodies
Therapeutics that treat multiple sclerosis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
 
Psoriasis  
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat psoriasis by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Immune Deficiency Disorders
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • ViiV Healthcare Selzentry (Maraviroc)
 
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Target Products:

  • Fuzeon (Enfuvirtide)
 
Integrase Inhibitors
Therapeutics that help manage HIV by blocking the integration of the HIV virus' genetic material into the host cell.

Buyer Products:

  • ViiV Healthcare - GSK1349572 / Dolutegravir (Integrase Inhibitor)
 
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare Rescriptor (Delavirdine Mesylate)
 
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare Combivir (Lamivudine/Zidovudine)
  • ViiV Healthcare Epivir (Lamivudine)
  • ViiV Healthcare Epzicom (Abacavir/Lamivudine)
  • ViiV Healthcare Retrovir (Zidovudine)
  • ViiV Healthcare Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • ViiV Healthcare Ziagen (Abacavir Sulfate)
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • ViiV Healthcare Lexiva (Fosamprenavir Calcium)
  • ViiV Healthcare Viracept (Nelfinavir Mesylate)

Target Products:

  • Invirase (Saquinavir Mesylate)
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • MultiStem IBD Program (Adult Human Stem Cells)
  • ViiV Healthcare PF-232798
  • ADL5859/PF-04856880 (Delta Opioid Receptor Agonist)
  • PF-5212367/ILV-094
  • ViiV Healthcare GSK1265744
  • ViiV Healthcare GSK2248761/IDX899 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • PF-4236921
  • PF-4308515
  • PF-5212368
  • PF-5212374/TRU-015 (Small Modular Immunopharmaceutical (SMIP))
  • PF-05230895/SBI-087 (SMIP CD20 Modulator)
  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)
  • PF-4171327
  • PF-3475952
  • ViiV Healthcare UK-453061
  • PH-797804
  • CE-224535
  • ViiV Healthcare PF-3716539 (PK Enhancer)
  • ViiV Healthcare 708769 (CCR5 Antagonist)

Target Products:

  • RG4934 (Anti-IL-17 Monoclonal Antibody)
  • RG7416 (Anti-LT Alpha Monoclonal Antibody)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • Genentech - Rituxan (Rituximab)
  • R1487 (Kinase Inhibitor)
  • Rontalizumab/RG7415 (Anti-IFN Alpha Monoclonal Antibody)
  • BAL2299 (Nuclear Receptor Modulator)
  • RG7413 (Anti-Beta 7 Monoclonal Antibody)
  • Genentech - MTRX1011A (anti-CD4 Monoclonal Antibody)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  • R1295 (Integrin Antagonist)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Icagen, Inc. - Senicapoc/Formerly ICA-17043 (Potassium Channel Blocking Agent)
  • Icagen, Inc. - Ion Channel Inflammatory Disorder Program

Target Products:

  • CRACM (Calcium Release-Activated Calcium Modulator) Ion Channel Inhibitor
  • CLIP (Class II Associated Invariant Chain Peptide)
Infectious Diseases
Bacterial
Antibacterial Agents
Broad Spectrum
Antibiotics
Aminoglycosides
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis.

Buyer Products:

  • Streptomycin Sulfate
 
Cephalosporin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Cefobid (Cefoperazone Sodium)
  • Vantin (Cefpodoxime)
  • Suprax (Cefixime)

Target Products:

  • Rocephin (Ceftriaxone Sodium)
  • Ceftobiprole Medocaril/BAL5788 (Antibiotic)
Glycylcyclines
Therapeutics that treat a wide variety of infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes. This class of antibiotics is a group of tetracycline analogues developed to target tetracycline-resistant strains of bacteria.

Buyer Products:

  • Tygacil (Tigecycline)
 
Lincosamides
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis.

Buyer Products:

  • Lincocin (Lincomycin Hydrochloride)
  • Cleocin Phosphate (Clindamycin Phosphate)
  • Cleocin HCL (Clindamycin Hydrochloride)
 
Macrolides
Therapeutics that treat a wide variety of infections by inhibiting RNA-dependent bacterial protein synthesis.

Buyer Products:

  • Zmax (Azithromycin Extended Release)
  • Zithromax I.V. (Azithromycin)
  • Zithromax (Azithromycin)
 
Nitroimidazoles
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis and causing cell death.

Buyer Products:

  • Flagyl/Flagyl ER (Metronidazole)
 
Oxazolidinones
Therapeutics that treat a wide variety of infections by inhibiting early initiation of bacterial protein synthesis.

Buyer Products:

  • Zyvox (Linezolid)
 
Penicillin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Bicillin L-A/L-A Pediatric (Penicillin G Benzathine Injectable Suspension)
  • Bicillin C-R/C-R 900/300/C-R Pediatric (Penicillin G Benzathine/Penicillin G Procaine Injectable Suspension)
  • Permapen Isoject (Penicillin G Benzathine)
  • Penicillin G Procaine Injectable Suspension
  • Unasyn (Ampicillin Sodium/Subbactam Sodium)
  • Pfizerpen (Penicillin G Potassium)
  • Bicillin L-A (Penicillin G Benzathine Suspension)
  • Bicillin C-R (Penicillin G Benzathine And Penicillin G Procaine Suspension)
 
Penicillin Derivatives/Beta-Lactamase Inhibitors
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication and increasing susceptibility to penicillin derived compounds.

Buyer Products:

  • Zosyn (Piperacillin/Tazobactam)
 
Quinolones/Fluoroquinolones
Therapeutics that treat a wide variety of infections by promoting breakage of bacterial DNA strands.

Buyer Products:

  • Maxaquin (Lomefloxacin Hydrochloride)
  • Synercid (Quinupristin/Dalfopristin)
 
Tetracyclines
Therapeutics that treat a wide variety of infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Buyer Products:

  • Vibramycin Hyclate (Doxycycline Hyclate)
  • Vibramycin Calcium (Doxycycline Calcium)
  • Vibra-Tabs (Doxycycline Hydrate)
  • Declomycin (Demeclocycline Hydrochloride)
  • Minocin (Minocycline Hydrochloride)
 
Narrow Spectrum
Dermatology  
Dermatoses  
Steroidal Anti-Inflammatory Drugs (SAID)/Antibacterial Agents (Antibiotics)
Therapeutics that treat bacterial infections of the skin with a steroidal compound and a compound that kills or inhibits the growth of bacteria.

Buyer Products:

  • Cortisporin (Neomycin/Polymyxin B Sulfates/Hydrocortisone Acetate) Cream/Ointment
 
Skin/Soft Tissue Infections  
Penicillin Derivatives
Therapeutics that treat dermal infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Spectrobid (Bacampicillin HCl)
 
Sulfonamides
Therapeutics that treat specific bacterial infections by inhibiting folic acid synthesis.

Buyer Products:

  • Silvadene (Silver Sulfadiazine)
 
Digestive System  
Shigellosis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat an infection of the intestines caused by Shigella by inhibiting folic acid synthesis.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Musculoskeletal System  
Skin/Soft Tissue Infections  
Penicillin Derivatives
Therapeutics that treat bacterial infections of non-skeletal tissue usually involving fat, muscle, and skin by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Spectrobid (Bacampicillin HCl)
 
Sulfonamides
Therapeutics that treat bacterial infections of non-skeletal tissue usually involving fat, muscle, and skin by inhibiting folic acid synthesis.

Buyer Products:

  • Silvadene (Silver Sulfadiazine)
 
Ophthalmology  
Ocular Infections  
Aminoglycosides/Polypeptides
Therapeutics that treat bacterial infections of the eye by inhibiting bacterial protein synthesis and damaging the cell membrane.

Buyer Products:

  • Neosporin Ophthalmic (Neomycin Sulfate B/Polymyxin Sulfate B/Gramicidin) Ointment/Solution Sterile
 
Aminoglycosides/Polypeptides/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat bacterial infections of the eye by inhibiting bacterial protein synthesis, damaging the cell membrane, and suppressing the full immune response.

Buyer Products:

  • Cortisporin Ophthalmic (Neomycin/Polymyxin B Sulfates/Bacitracin Zinc/Hydrocortisone) Ointment/Suspension Sterile
 
Tetracyclines/Polypeptides
Therapeutics that treat bacterial infections of the eye by inhibiting protein synthesis and damaging the cell membrane.

Buyer Products:

  • Terramycin (Oxytetracycline HCl/Polymyxin B Sulfate)
 
Tetracyclines/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat bacterial infections of the eye by inhibiting protein synthesis, damaging the cell membrane and suppressing the full immune response.

Buyer Products:

  • Terra-Cortril (Oxytetracycline Hydrochloride/Hydrocortisone Acetate)
 
Otolaryngology (Ear/Nose/Throat)
External Ear Canal Infections  
Steroidal Anti-Inflammatory Drugs (SAID)/Antibacterial Agents (Antibiotic)
Therapeutics that treat bacterial infections of the external auditory canal with a steroidal compound and by killing or inhibiting the growth of microorganisms.

Buyer Products:

  • Pediotic Suspension Sterile (Neomycin/Polymyxin B Sulfates/Hydrocortisone)
  • Cortisporin-TC Otic (Colistin Sulfate/Neomycin Sulfate/Thonzonium Bromide/Hydrocortisone Acetate)
  • Cortisporin Otic (Neomycin/Polymyxin B Sulfate/Hydrocortisone) Solution/Suspension Sterile
 
Otitis Media
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the middle ear inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Septra (Sulfamethoxazole/Trimethoprim) IV Infusion/Tablets/Suspension

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
Macrolides
Therapeutics that treat infection and inflammation of the middle ear space and ear drum by inhibiting RNA-dependent bacterial protein synthesis.

Buyer Products:

  • Zithromax (Azithromycin)
 
Respiratory System
Bronchitis
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the bronchi in the lungs by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Septra (Sulfamethoxazole/Trimethoprim) IV Infusion/Tablets/Suspension

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
Pneumonia  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat inflammation of the lungs caused by bacterial infection by inhibiting folic acid synthesis and bacterial growth.

Buyer Products:

  • Septra (Sulfamethoxazole/Trimethoprim) IV Infusion/Tablets/Suspension
 
Polypeptides
Therapeutics that treat bacterial infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Bacitracin
 
Respiratory Tract Infections  
Penicillin Derivatives
Therapeutics that treat bacterial infections of the air passage involved in breathing, including the trachea, lungs and bronchi by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Spectrobid (Bacampicillin HCl)
 
Tuberculosis  
Antitubercular Agents
Therapeutics that treat a bacterial infection of the lung by inhibiting bacterial and mycobacterial RNA synthesis.

Buyer Products:

  • Myambutol (Ethambutol Hydrochloride)
  • Trecator-SC (Ethionamide)
  • Trecator (Ethionamide)
 
Systemic  
Mycobacterium Avium Complex (MAC) Disease  
Antitubercular Agents
Therapeutics that treat infection caused Mycobacterium avium in soil that spreads to a variety of organs and tissues by inhibiting bacterial and mycobacterial RNA synthesis.

Buyer Products:

  • Mycobutin (Rifabutin)
 
Urology
Gonorrhea  
Penicillin Derivatives
Therapeutics that treat a common sexually transmitted disease caused by gonococcus bacterium by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Spectrobid (Bacampicillin HCl)
 
Urinary Tract Infections (UTI)
Antibacterial Agents (Antibiotics)
Aminoglycosides
Therapeutics that treat bacterial infections of the urethra, urinary bladder, ureters, and kidneys by inhibiting bacterial protein synthesis.

Buyer Products:

  • Neosporin G.U. Irrigant (Neomycin Sulfate/Polymyxin B Sulfate)
 
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections of the urinary tract by inhibiting dihydrofolate reductase resulting in decreased bacterial nucleic acid/protein production.

Buyer Products:

  • Septra (Sulfamethoxazole/Trimethoprim) IV Infusion/Tablets/Suspension

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
Penicillin Derivatives
Therapeutics that treat bacterial infections of the urethra, urinary bladder, ureters, and kidneys by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Spectrobid (Bacampicillin HCl)
  • Geocillin (Carbenicillin Idanyl Sodium)
 
Vaginitis  
Lincosamides
Therapeutics that treat inflammation of the mucous membrane of the vagina caused by bacterial infection by inhibiting bacterial protein synthesis.

Buyer Products:

  • Cleocin (Clindamycin Phosphate) Vaginal Ovules
  • Cleocin (Clindamycin Phosphate) Vaginal Cream
 
Vaccines  
Bacterial  
Combination  
Diphtheria/Tetanus (DT)
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause diphtheria and tetanus.

Buyer Products:

  • Diphtheria And Tetanus Toxoids Adsorbed
 
Single Target  
Haemophilus Influenzae Type B (Hib)
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause Haemophilus influenzae type B.

Buyer Products:

  • Hibtiter (Haemophilus b Conjugate Vaccine (Diphtheria CRM197 Protein Conjugate))
 
Streptococcus pneumoniae
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause pneumococcal bacteria.

Buyer Products:

  • Prevnar/Prevenar (7-valent) Pneumonococcal Conjugate Vaccine
  • Prevnar 13 (Pneumococcal 13-Valent Conjugate Vaccine (Diphtheria CRM197 Protein))
 
Typhoid Fever
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause typhoid fever.

Buyer Products:

  • Typhoid Vaccine
 
Bacterial/Viral
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to a bacterial or viral pathogen.

Buyer Products:

  • Prevnar/Prevenar (7-valent) Pneumonococcal Conjugate Vaccine
 
Mycological (Fungal)
Antifungal Agents
Broad Spectrum
Azoles
Triazoles
Therapeutics that treat fungal infections by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Vfend (Voriconazole)

Target Products:

  • Isavuconazole/BAL8557 (Antifungal Agent)
Echinocandins
Therapeutics that treat fungal infections by inhibiting the synthesis of a major cell wall component.

Buyer Products:

  • Eraxis (Anidulafungin)
 
Narrow Spectrum
Digestive System  
Mucous  
Candidiasis  
Echinocandins
Therapeutics that treat fungal infections due to candidiasis through a broad spectrum fungicidal action.

Buyer Products:

  • Eraxis (Anidulafungin)
 
Nervous System  
Cryptococcal Meningitis  
Triazoles
Therapeutics that treat fungal infections of lining of the brain and the spinal cord by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Diflucan (Fluconazole)
 
Otolaryngology (Ear/Nose/Throat)  
Esophageal Candidiasis  
Triazoles
Therapeutics that treat fungal infections of the esophagus caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Vfend (Voriconazole)
  • Diflucan (Fluconazole)
 
Oropharyngeal Candidiasis  
Azoles  
Triazoles
Therapeutics that treat fungal infections of the mouth and pharynx caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Diflucan (Fluconazole)
 
Respiratory System  
Pneumocystis Carinii Pneumonia (PCP)  
Dihydrofolate Reductase Inhibitors/Dihydropteroate Synthetase Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by interfering with folic acid synthesis and growth of organism.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Urology  
Vaginal Candidiasis  
Azoles  
Triazoles
Therapeutics that treat fungal infections of the female reproductive organ caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Diflucan (Fluconazole)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Buyer Products:

  • PF-06290510 (4-Antigen Staphylococcus Aureus Vaccine (SA4Ag))
  • ViiV Healthcare PF-232798
  • ViiV Healthcare GSK1265744
  • ViiV Healthcare GSK2248761/IDX899 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • PF-4287881
  • PF-5230894
  • PF-05212366/MnB rLP2086
  • ViiV Healthcare UK-453061
  • PF-868554 (HCV Protease Inhibitor)
  • Sulopenem Oral Prodrug/Sulponen IV
  • Moxidectin
  • ViiV Healthcare PF-3716539 (PK Enhancer)
  • ViiV Healthcare 708769 (CCR5 Antagonist)
  • PF-2341272/PNU-100480

Target Products:

  • Serine Palmitoyl Transferase Inhibitor
  • CS-023 (Parenteral Carbapenem)
  • RG7227 (Danoprevir)/Formerly ITMN-191
  • Ceftobiprole Medocaril/BAL5788 (Antibiotic)
  • Isavuconazole/BAL8557 (Antifungal Agent)
  • R1270 (Levovirin)
  • Mericitibine/Formerly RG7128/RO5024048 (Cytidine Nucleoside Analog Prodrug)
  • RG7432 (Nucleoside Polymerase Inhibitor)
  • RG7348 (Nucleoside Analogue)
  • R1461 (Fusion Protein)
  • R1479 (Polymerase Inhibitor)
Protozoal  
Antiprotozoal Agents  
Broad Spectrum  
Nitroimidazoles
Therapeutics that treat infections caused by a wide variety of unicellular organisms by inhibiting protein synthesis and causing cell death.

Buyer Products:

  • Flagyl/Flagyl ER (Metronidazole)
 
Narrow Spectrum  
Malaria  
Aminoquinolines/Macrolides
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by inhibiting parasite growth and inhibiting RNA-dependent protein synthesis.

Buyer Products:

  • Azithromycin/Chloroquine
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in very early stages of research where no human subject is involved.

Buyer Products:

  • BLI-489

Target Products:

  • Tamiflu (Oseltamivir)
  • BAL8349 (Antifungal Agent)
Viral
DNA Viruses
Hepadnavirus  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months with natural proteins that have antiviral activity.

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
 
Herpesvirus
Cytomegalovirus (CMV)  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
 
Herpes Simplex Type 1  
Viral DNA Polymerase Inhibitors
Therapeutics that treat viral infections characterized by recurrent cold sores and fever blisters by inhibiting replication of viral DNA blocking the action of an essential enzyme.

Buyer Products:

  • Viroptic Ophthalmic Solution (Trifluridine)
 
Herpes Simplex Type 2  
Viral DNA Polymerase Inhibitors
Therapeutics that treat viral infections characterized by recurring outbreaks of painful genital lesions by inhibiting replication of viral DNA by blocking the action of an essential enzyme.

Buyer Products:

  • Viroptic Ophthalmic Solution (Trifluridine)
 
RNA Viruses
Flavivirus  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections characterized by long term inflammation of the liver by enhancing the immune system and by inhibiting replication of viral DNA.

Target Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
 
Orthomyxovirus  
Influenza A  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza A virus by preventing the release of new viruses from infected cells.

Target Products:

  • Tamiflu (Oseltamivir)
 
Influenza B  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza B virus by preventing the release of new viruses from infected cells.

Target Products:

  • Tamiflu (Oseltamivir)
 
Retrovirus
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • ViiV Healthcare Selzentry (Maraviroc)
 
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Target Products:

  • Fuzeon (Enfuvirtide)
 
Integrase inhibitors
Therapeutics that help manage HIV by blocking the integration of the HIV virus' genetic material into the host cell.

Buyer Products:

  • ViiV Healthcare - GSK1349572 / Dolutegravir (Integrase Inhibitor)
 
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare Rescriptor (Delavirdine Mesylate)
 
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare Combivir (Lamivudine/Zidovudine)
  • ViiV Healthcare Epivir (Lamivudine)
  • ViiV Healthcare Epzicom (Abacavir/Lamivudine)
  • ViiV Healthcare Retrovir (Zidovudine)
  • ViiV Healthcare Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • ViiV Healthcare Ziagen (Abacavir Sulfate)
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • ViiV Healthcare Lexiva (Fosamprenavir Calcium)
  • ViiV Healthcare Viracept (Nelfinavir Mesylate)

Target Products:

  • Invirase (Saquinavir Mesylate)
Musculoskeletal System
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • ADL5859/PF-04856880 (Delta Opioid Receptor Agonist)
  • PF-5212367/ILV-094
  • SD-6010
  • PF-5208771 (Dibotermin alfa)
  • PF-4236921
  • PF-5212368
  • PF-5212371
  • Recombinant Human Bone Morphogenetic Protein (rhBMP-2)
  • PF-5212374/TRU-015 (Small Modular Immunopharmaceutical (SMIP))
  • PF-05230895/SBI-087 (SMIP CD20 Modulator)
  • PF-4171327
  • PF-3475952
  • CP-533536
  • PH-797804
  • CE-224535

Target Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
  • RG7416 (Anti-LT Alpha Monoclonal Antibody)
  • RG4934 (Anti-IL-17 Monoclonal Antibody)
  • R1487 (Kinase Inhibitor)
  • Genentech - MTRX1011A (anti-CD4 Monoclonal Antibody)
  • R1295 (Integrin Antagonist)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • rhCD-RAP (Recombinant Human Cartilage Specific Growth Factor)
 
Skeletal Disorders
Bone Disorders
Bone Fractures  
Growth Factor  
Recombinant Human Bone Morphogenetic Protein (rhBMP)
Therapeutics that induce the formation of bone and cartilage.

Buyer Products:

  • Recombinant Human Bone Morphogenetic Protein (rhBMP-2)
 
Osteoporosis
Estrogens/Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by providing female hormones and other endocrine modulating substances which decrease the rate of bone loss.

Buyer Products:

  • Aprela (Bazedoxifene/Conjugated Estrogen) [Pfizer-Ligand Pharmaceuticals Collaboration]
 
Hormonal Treatments  
Estrogens
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Buyer Products:

  • Ogen (Estropipate)
  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
  • Delestrogen (Estradiol Valerate Injection, USP)
 
Estrogens/Progestins
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Buyer Products:

  • Prempro/Low-Dosage Prempro (Conjugated Estrogens/Medroxyprogesterone Acetate)
 
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts.

Target Products:

  • Boniva (Ibandronate Biphosphonate)
 
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts while not stimulating the endometrial lining of the uterus.

Buyer Products:

  • Fablyn (Lasofoxifene)
  • Viviant (Bazedoxifene)/CONBRIZA

Target Products:

  • Evista (Raloxifene Hydrochloride)
Joint Disorders
Ankylosing Spondylitis
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat ankylosing spondylitis interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Actemra (Tocilizumab)
 
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat ankylosing spondylitis by selectively blocking cyclooxygenase 2.

Buyer Products:

  • Celebrex (Celecoxib)
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat ankylosing spondylitis by blocking the effect of TNF-alpha, a pro-inflammatory molecule.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Dupuytren`s Disease  
Debriding Agents
Therapeutics that treat Depuytren's Disease by removing the fibrous material from in/around the palm of the hand.

Buyer Products:

  • Xiapex (Collagenase Clostridium Histolyticum)
 
Fibromyalgia Syndrome (FMS)  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Fibromyalgia Syndrome by preventing the uptake of gamma-aminobutyric acid, which prevent nerve activation.

Buyer Products:

  • Lyrica (Pregabalin)
 
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat Fibromyalgia Syndrome by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Pristiq (Desvenlafaxine Succinate Extended Release)
 
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by inhibiting cyclooxygenase activity.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Osteoarthritis (OA)
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat inflammation by specifically inhibiting the action of cyclooxygenase-2.

Buyer Products:

  • Celebrex (Celecoxib)
  • Bextra (Valdecoxib)
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Feldene (Piroxicam)
  • Daypro/Daypro Alta (Oxaprozin)
  • Ansaid (Flurbiprofen)
  • Oruvail (Ketoprofen)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/GI Protective Agents
Therapeutics that treat inflammation by inhibiting the action of prostaglandins while simultaneously protecting the stomach from the pain killing medication.

Buyer Products:

  • Arthrotec (Diclofenac/Misoprostol)
 
Psoriatic Arthritis  
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat chronic inflammation of the joints by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Rheumatoid Arthritis (RA)
Analgesics
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by selectively blocking cyclooxygenase 2 activity.

Buyer Products:

  • Celebrex (Celecoxib)
  • Bextra (Valdecoxib)
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Feldene (Piroxicam)
  • Daypro/Daypro Alta (Oxaprozin)
  • Ansaid (Flurbiprofen)
  • Oruvail (Ketoprofen)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/GI Protective Agents
Therapeutics that treat pain associated with chronic inflammation of the joints, without upsetting the stomach with a non-steroidal compound and an anti-ulcer agent.

Buyer Products:

  • Arthrotec (Diclofenac/Misoprostol)
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Janus-Associated Kinase (JAK) Inhibitors
Therapeutics that treat rheumatoid arthritis by selectively inhibiting the production of a variety of inflammatory causing cytokines.

Buyer Products:

  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)
 
Immunotherapy
Immunosuppressants
Therapeutics that treat rheumatoid arthritis by suppressing the immune system.

Buyer Products:

  • Azulfidine/Azulfidine EN-Tabs (Sulfasalazine)
 
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Actemra (Tocilizumab)
  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
 
Tumor Necrosis Factor-Alpha Antagonists (TNF-Alpha Antagonists)
Therapeutics that treat chronic inflammation of the joints by blocking the action of tumor necrosis factor.

Buyer Products:

  • Enbrel/Enbrel Once-Weekly (Etanercept)
 
Neurology
Neurological Disorders
Alzheimer`s Disease  
Acetylcholinesterase Inhibitors
Therapeutics that treat Alzheimer's Disease by preventing the breakdown of a the neurotransmitter, acetylcholine.

Buyer Products:

  • Aricept Skin Patch (Donepezil Hydrochloride)
  • Aricept 23 (Donepezil Hydrochloride Extended Release)
  • Aricept (Donepezil Hydrochloride)
 
Mitochondrial Pore Blockers
Therapeutics that treat Alzheimer's Disease by blocking molecules transport across mitochondrial pores, which may lead to the prevention of brain cell death.

Buyer Products:

  • Dimebon (Latrepirdine)
 
Monoclonal Antibodies
Therapeutics that treat Alzheimer's Disease by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Bapineuzumab (Beta Amyloid Inhibitor)
 
Epilepsy
Partial Seizures  
Complex  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid, which prevent nerve activation.

Buyer Products:

  • Lyrica (Pregabalin)
  • Neurontin (Gabapentin)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid, that prevents nerve activation.

Buyer Products:

  • Lyrica (Pregabalin)
 
Sodium Channel Modulators
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Buyer Products:

  • Dilantin (Phenytoin Sodium)
 
Primary Generalized Seizures
Absence (Petit Mal)
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Monotherapy
Calcium Channel Blocking Agents
Therapeutics that treat Petit Mal Seizures by preventing the entrance of calcium into nerve cells.

Buyer Products:

  • Celontin (Methsuximide)
  • Zarontin (Ethosuximide)
 
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Akinetic Pattern  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Myoclonic  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevent nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
 
Tonic-Clonic (Grand Mal)  
Sodium Channel Modulators
Therapeutics that treat Grand Mal Seizures by modulating the gates which allow sodium into nerve cells.

Buyer Products:

  • Dilantin (Phenytoin Sodium)
 
Status Epilepticus  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat status epilepticus by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Vanquix (Diazepam Auto-Injection)
 
Sodium Channel Modulators
Therapeutics that treat Status Epilepticus by modulating the portal that allows sodium into the nerve cells.

Buyer Products:

  • Cerebyx (Fosphenytoin Sodium)
 
Headaches  
Vascular (Migraine)  
Acute Treatments  
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat vascular/migraine headaches by stimulating the receptor that binds with the neurotransmitter, serotonin.

Buyer Products:

  • Relpax (Eletriptan)
 
Prophylactic Treatments  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat Migraine by inhibiting stimulation of beta adrenergic receptors.

Buyer Products:

  • Inderal LA Long-Acting Capsules (Propranolol Hydrochloride)
 
Huntington`s Disease (Huntington`s Chorea)  
Mitochondrial Pore Blockers
Therapeutics that treat Huntington's Disease by blocking molecules transport across mitochondrial pores, which may lead to the prevention of brain cell death.

Buyer Products:

  • Dimebon (Latrepirdine)
 
Motion Sickness  
Antivertigo Agents
Therapeutics that prevent the sensation of motion.

Buyer Products:

  • Antivert (Meclizine HCl)
 
Neuromuscular Disorders
Multiple Sclerosis (MS)
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that down regulates the antibody response of the immune system.

Buyer Products:

  • Rebif (Recombinant Interferon Beta-1a)
 
Monoclonal Antibodies
Therapeutics that treat multiple sclerosis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Genentech - Rituxan (Rituximab)
 
Neuropathy  
Transthyretin (TTR) Amyloidosis  
Transthyretin (TTR) Stabilizers
Therapeutics that treat Transthyretin Amyloidosis, a hereditary form of neuropathy, also known as Familial amyloid polyneuropathy (FAP), by stabilizing the transthyretin protein.

Buyer Products:

  • Tafamidis Meglumine
 
Parkinson`s Disease (PD)
Adjunctive Treatments  
Dopamine Receptor Agonists
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on neurons.

Target Products:

  • Madopar DR (Levodopa)
 
Monotherapy  
Dopamine Receptor Agonists
Therapeutics that treat the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on the neurons.

Buyer Products:

  • Mirapex (Pramipexole Dihydrochloride)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • ACC-001/PF-05236806
  • PF-4447943
  • Icagen, Inc. - ICA-105665 (Potassium Channel Activator Compound)
  • PF-4455242
  • PF-5212362/Begacestat
  • PF-5212377
  • PF-4427429
  • PF-5236806/ACC-001 (A-beta Immunotherapeutic Conjugate Vaccine)
  • PD-332334
  • PF-5208769/Vabicaserin
  • PF-5212365/SAM-531
  • Tafamidis Meglumine
  • PF-3654746
  • PF-04360365
  • PF-3463275
  • PF-3084014
  • PF-2400013
  • PF-217830
  • PH-797804

Target Products:

  • RG1578 (mGluR2 Antagonist)
  • RG1662 (GABA-A Alpha5 Inverse Agonist)
  • RG7090 (mGluR5 Antagonist)
  • RG7166 (Triple Reuptake Inhibitor)
  • R4996/MEM 63908 (Nicotinic Alpha-7 Receptor Agonist)
  • RG3487/MEM 3454 (Nicotinic Alpha-7 Receptor Partial Agonist)
  • Genentech - Rituxan (Rituximab)
  • MT 500 (GPCR Modulator)
  • RG1450/Gantenerumab (Amyloid Beta Peptide Antibody)
  • EVT 103 (NMDA Receptor Antagonist)
  • EVT 101 (NMDA Receptor Antagonist)
  • RG7412 (Anti-A Beta Monoclonal Antibody)
Psychiatric Disorders
Anxiety
Generalized Anxiety Disorder (GAD)
Antihistamines
Therapeutics that treat anxiety by blocking the action of histamines.

Buyer Products:

  • Vistaril (Hydroxyzine Pamoate)
  • Vistaril (Hydroxyzine Hydrochloride)
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Xanax/Xanax XR (Alprazolam)

Target Products:

  • Valium (Diazepam)
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat anxiety by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Effexor XR (Venlafaxine Hydrochloride Extended Release)
  • Effexor (Venlafaxine Hydrochloride)
 
Tricyclic Compounds
Therapeutics that treat anxiety by increasing the synaptic concentrations of norepinephrine and serotonin.

Buyer Products:

  • Sinequan (Doxepin HCl)
 
Obsessive Compulsive Disorder (OCD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Anxiety by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Panic Disorder
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Xanax/Xanax XR (Alprazolam)

Target Products:

  • Klonopin (Clonazepam)
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat panic disorder by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Effexor XR (Venlafaxine Hydrochloride Extended Release)
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat panic disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Post-Traumatic Stress Disorder (PTSD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat post traumatic stress disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Social Anxiety Disorder (SAD)  
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Effexor XR (Venlafaxine Hydrochloride Extended Release)
  • Effexor (Venlafaxine Hydrochloride)
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Mood Disorders  
Bipolar Disorders (Manic Depressive Disorders)  
Serotonin/Dopamine Receptor Blocking Agents
Therapeutics that treat bipolar disorders by blocking serotonin and dopamine receptors.

Buyer Products:

  • Geodon (Ziprasidone Mesylate)
 
Tricyclic Compounds
Therapeutics that treat bipolar disorders by increasing the synaptic concentrations of norepinephrine and serotonin.

Buyer Products:

  • Sinequan (Doxepin HCl)
 
Depression  
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat depression by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Buyer Products:

  • Effexor XR (Venlafaxine Hydrochloride Extended Release)
  • Effexor (Venlafaxine Hydrochloride)
  • Pristiq (Desvenlafaxine Succinate Extended Release)
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat depression by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Tricyclic Compounds
Therapeutics that treat depression by increasing the synaptic concentrations of norepinephrine and serotonin.

Buyer Products:

  • Sinequan (Doxepin HCl)
  • Surmontil (Trimipramine Maleate)
 
Premenstrual Dysphoric Disorders  
Estrogens/Progestins
Therapeutics that treat premenstrual dysphoric disorders by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus.

Buyer Products:

  • Lybrel (Levonorgestrel/Ethinyl Estradiol)
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat premenstrual dysphoric disorders by selectively preventing the removal of serotonin.

Buyer Products:

  • Zoloft (Sertraline Hydrochloride)
 
Schizophrenia
Dopamine Receptor Blocking Agents
Therapeutics that treat schizophrenia by blocking the dopamine receptors.

Buyer Products:

  • Navane (Thiothixene)
 
Glycine Reuptake Inhibitors
Therapeutics that treat schizophrenia by inhibiting the reuptake of glycine by neurotransmitters.

Target Products:

  • RG1678
 
Serotonin/Dopamine Receptor Blocking Agents
Therapeutics that treat schizophrenia by blocking serotonin and dopamine receptors.

Buyer Products:

  • Geodon (Ziprasidone Mesylate)
 
Serotonin/Dopamine Receptor Partial Agonists
Therapeutics that treat schizophrenia by enhancing activity in both serotonin and dopamine receptors.

Buyer Products:

  • Bifeprunox
 
Sleep Disorders  
Insomnia  
Antihistamines/Analgesics/Antipyretics
Therapeutics that treat insomnia by preventing the functions of histamine on tissues as well as treating pain and suppressing fever.

Buyer Products:

  • Advil PM (Ibuprofen/Diphenhydramine HCl)
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat insomnia by enhancing the inhibitory action of gamma-aminobutyric acid.

Buyer Products:

  • Sonata CIV (Zaleplon)
  • Halcion (Triazolam)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • TS-032
  • AAB-002
  • SRA-444
  • SCA-171
  • SAM-610
  • Neurodegenerative Diseases Program
 
Obstetrics/Gynecology  
Child Birth/Pregnancy  
Hemorrhage  
Prostaglandins
Therapeutics that treat hemorrhage by acting as vasoconstrictors, thus reducing blood flow.

Buyer Products:

  • Hemabate (Carboprost)
 
Induction/Cervical Ripening  
Oxytocic Agents
Therapeutics that induce contractions by increasing the levels of intracellular calcium in the uterine smooth muscle thus mimicking uterine contractions and transiently impeding uterine blood flow.

Buyer Products:

  • Pitocin (Oxytocin)
 
Prostaglandins
Therapeutics that induce contractions by acting directly on the myometrium thus stimulating myometrial contractions in the uterus.

Buyer Products:

  • Prepidil (Dionprostone)
 
Prevention (Contraception)  
Contraceptives (Birth Control)  
Estrogens
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Buyer Products:

  • Demulen (Ethynodiol Diacetate/Ethinyl Estradiol)
 
Estrogens/Progestins
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Buyer Products:

  • Alesse (Levonorgestrel/Ethinyl Estradiol)
  • Lybrel (Levonorgestrel/Ethinyl Estradiol)
  • Lo/Ovral (Norgestrel/Ethinyl Estradiol)
  • Triphasil (Levonorgestrel/Ethinyl Estradiol)
 
Progestins
Contraceptive Therapeutics that are female sex hormone necessary for the development of the female reproductive system

Buyer Products:

  • Depo-Provera/Depo-SubQ Provera 104 (Medroxyprogesterone Acetate)
 
Termination (Abortion)  
Prostaglandins
Therapeutics that induce contractions by acting directly on the myometrium thus stimulating myometrial contractions in the uterus.

Buyer Products:

  • Prostin E2 (Dinoprostone)
  • Hemabate (Carboprost)
 
Female Genital Disorders  
Endometriosis  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat endometriosis by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Buyer Products:

  • Synarel (Nafarelin Acetate)
 
Progestins
Therapeutics that treat endometriosis pain by increasing progesterone level in the body.

Buyer Products:

  • Depo-Provera/Depo-SubQ Provera 104 (Medroxyprogesterone Acetate)
 
Ovarian  
Abnormal Puberty  
Delayed  
Androgens
These therapeutics are male sex hormones.

Buyer Products:

  • Halotestin (Fluoxymesterone)
 
Hypogonadism  
Hormonal Treatments  
Estrogens
These are female sex hormones.

Buyer Products:

  • Menest (Esterified Estrogens Tablets)
  • Delestrogen (Estradiol Valerate Injection, USP)
 
Vulvovaginal  
Atrophy  
Hormonal Treatments  
Estrogens
Therapeutics that treat disorders characterized by thinning of the vaginal walls with the female sex hormone estrogen.

Buyer Products:

  • Menest (Esterified Estrogens Tablets)
  • Ogen (Estropipate)
  • Estring (Estradiol)
  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
  • Premarin Vaginal Cream (Conjugated Estrogens)
  • Delestrogen (Estradiol Valerate Injection, USP)
 
Estrogens/Progestins
Therapeutics that treat disorders characterized by thinning of the vaginal walls with a combination of the female sex hormones estrogen and progestin.

Buyer Products:

  • Prempro/Low-Dosage Prempro (Conjugated Estrogens/Medroxyprogesterone Acetate)
 
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat disorders characterized by thinning of the vaginal walls blocking estrogen receptors.

Buyer Products:

  • Fablyn (Lasofoxifene)
 
Dryness  
Estrogens
These are female sex hormones.

Buyer Products:

  • Premarin Vaginal Cream (Conjugated Estrogens)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of female reproductive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PF-4418948
  • NSP-989 (Tanaproget)
 
Oncology
Breast Cancer
Localized
Aromatase Inhibitors
Therapeutics that treat and manage breast cancer by interfering with estrogen production in peripheral tissues.

Buyer Products:

  • Aromasin (Exemestane)
 
Monoclonal Antibodies
Therapeutics that treat breast cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Genentech - Herceptin (Trastuzumab)/Avastin (Bevacizumab)
  • Herceptin (Trastuzumab)
 
Topoisomerase II Inhibitors
Therapeutics that treat breast cancer by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Tyrosine Kinase Inhibitors
Therapeutics that treat localized breast cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Neratinib
 
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage breast cancers that have spread beyond their original tumor site by inhibiting the production of DNA.

Target Products:

  • Xeloda (Capecitabine)
 
Aromatase Inhibitors
Therapeutics that treat and manage breast cancer by interfering with estrogen production in peripheral tissues.

Buyer Products:

  • Aromasin (Exemestane)
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of breast cancer cells and inhibit the cancer cells' growth and induce their death.

Target Products:

  • Herceptin (Trastuzumab)
  • Genentech - Omnitarg (Pertuzumab)
  • Trastuzumab Emtansine (T-DM1)
  • Avastin (Bevacizumab)
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers of the breast that have spread beyond their original tumor site by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Ellence (Epirubicin HCL)
 
Palliative Agents  
Cardioprotective Agents
Therapeutics that help reduce damage to the heart caused by treatments for breast cancer by interfering with free radical generation which results in cardiomyopathy.

Buyer Products:

  • Zinecard (Dexrazoxane)
 
Hormonal Treatments  
Estrogens
Therapeutics that treat and manage breast cancer in post-menopausal women by providing female hormones.

Buyer Products:

  • Menest (Esterified Estrogens Tablets)
  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
 
Dermatology  
Basal Cell Carcinoma  
Hedgehog Pathway Inhibitors
Therapeutics that treat and manage cancers arising from the epidermal basal cells by inhibiting signaling in the Hedgehog pathway, which functions to regulate cell growth.

Target Products:

  • Erivedge (Vismodegib)
 
Kaposi`s Sarcoma  
Interferons
Therapeutics that treat and manage cancers of spindle cells by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Malignant Melanoma  
Raf Kinase Inhibitors
Therapeutics that treat skin cancer by interrupting the signaling pathways that are responsible for tumor cell proliferation.

Target Products:

  • Genentech - Zelboraf (Vemurafenib)/Formerly RG7204/PLX4032 (BRAF Kinase Inhibitor)
 
Digestive System
Colon Cancer/Colorectal Cancer
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage colorectal tumors that have spread beyond their original tumor site by inhibiting the production of DNA.

Target Products:

  • Xeloda (Capecitabine)
 
Monoclonal Antibodies
Therapeutics that treat colorectal cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
 
Topoisomerase I Inhibitors
Therapeutics that treat and manage colorectal cancers by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Camptosar (Irinotecan Hydrochloride)
 
Gastric Cancer (Stomach Cancer)
Localized  
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers of the stomach by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Tyrosine Kinase Inhibitors
Therapeutics that treat gastric cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Sutent (Sunitinib Malate)/Formerly SU-011248
 
Metastatic  
Monoclonal Antibodies
Therapeutics that treat gastric cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Herceptin (Trastuzumab)
 
Hepatic Cancer (Liver Cancer)  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage hepatic (liver) cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Target Products:

  • Genetech - Tarceva (Erlotinib)
 
Pancreatic Cancer
Localized  
Tyrosine Kinase Inhibitors
Therapeutics that treat localized pancreatic cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Sutent (Sunitinib Malate)/Formerly SU-011248
 
Metastatic  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Target Products:

  • Genetech - Tarceva (Erlotinib)
 
Endocrinology  
Thyroid Gland  
Localized  
Topoisomerase II Inhibitors
Therapeutics that treat and manage primary tumors of the thyroid gland by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Hematology
Leukemia (White Blood Cell Cancer)
Lymphoid
Acute  
Lymphoblastic  
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers of lymphocytic cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Chronic  
Hairy Cell  
Interferons
A recombinantly produced protein normally produced by the body to fight viral infection used to treat and manage a slowly progressing cancer of lymphoid cells characterized by numerous irregular cytoplasmic projections.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Lymphocytic (CLL)  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of leukemia cells and thereby induce their death.

Target Products:

  • Genentech - Rituxan (Rituximab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
 
Myeloid
Acute  
Myeloblastic  
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers affecting immature cells of the bone marrow by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Myelogenous (AML)  
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers of the myelogenous cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Idamycin/Idamycin PFS (Idarubicin Hydrochloride)
 
Chronic
Myelogenous (CML)
Interferons
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Tyrosine Kinase Inhibitors
Therapeutics that treat myelogenous cancers by inhibiting the action of tyrosine kinase, compounds that play a vital role in cell division.

Buyer Products:

  • Bosutinib/Formerly PF-5208763
 
Lymphoma (Lymphatic Cancer)
Hodgkin`s Disease  
Topoisomerase II Inhibitors
Therapeutics that treat and manage lymphoma characterized by the presence of Reed-Sternberg cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Non-Hodgkin`s Lymphoma (NHL)
Mammalian Target Of Rapamycin (mTOR) Inhibitors
Therapeutics that treat and manage lymphomas of B-cells and T-cells by inhibiting signals required for cell cycle progression, cell growth, and proliferation.

Buyer Products:

  • Torisel (Temsirolimus)
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of lymphoma cells and thereby induce their death.

Buyer Products:

  • Inotuzumab Ozogamicin (CD22-targeted Cytotoxic Agent)

Target Products:

  • Rituxan (Rituximab)/Avastin (Bevacizumab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
  • Genentech - Rituxan (Rituximab)
Neurology
Brain Cancer
Glioma  
Glioblastoma  
Monoclonal Antibodies
Therapeutics that treat and manage tumors of the glial cells by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
  • Bevacizumab/Temozolomide/Vorinostat Combination Therapy
 
Neuroblastoma  
Topoisomerase II Inhibitors
Therapeutics that treat a and manage cancer of primitive ganglion cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • PD-0332991
  • PF-03446962
  • PD-0325901
  • PF-03084014 (Gamma Secretase/Notch Pathway Inhibitor)
  • PF-05082566 (4-1BB Inhibitor)
  • PF-05212384 (PI3K/mTOR Dual Inhibitor)
  • PF-04605412 (?5?1 Inhibitor)
  • PF-562271
  • CP-870893 (CD40-Agonist Monoclonal Antibody)
  • CP-751871 (Figitumumab)
  • PF-1367338/AG-14699
  • PF-4948568 (Cancer Vaccine)
  • Inlyta (Axitinib)
  • PF-3512676 (Promune)
  • PF-4554878
  • PF-3758309
  • PF-4605412
  • PF-4691502
  • PF-4929113
  • PF-5208766/WAY-178357
  • Sutent (Sunitinib Malate)/Formerly SU-011248
  • PF-04691502 (PI3K/mTOR Inhibitor)
  • PF-04449913 (Smoothened (SMO) Inhibitor)
  • Bosutinib/Formerly PF-5208763
  • PF-477736
  • CVX 060/PF-04856884
  • PF-3732010
  • PF-4217903
  • PF-3446962
  • SU-14813
  • PF-3814735
  • CP-675206 (Tremelimumab)

Target Products:

  • RG7597 (Anti-HER3/EGFR Monoclonal Antibody)
  • RG1507 (IGF-1R Antagonist)
  • MKC-1/R440 (Cell Cycle Inhibitor)
  • CAL (Anti-PTHrP Monoclonal Antibody)
  • CHC 12103 (Polyglutamate TXL)
  • Therafab
  • R1549/Formerly Pemtumomab
  • Diflomotecan (Topoisomerase Inhibitor I)
  • E2F Activating Compound
  • ARQ 501/R1668 (E2F Modulator)
  • Trastuzumab Emtansine (T-DM1)
  • PRO64553 (Anti-CD40 Antibody)
  • Avastin (Bevacizumab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
  • R547 (Enzyme Inhibitor)
  • Vadimezan/AS1404
  • Genetech - Tarceva (Erlotinib)
  • Yervoy (Ipilimumab)/Vemurafenib (BRAF Kinase Inhibitor)
  • Erivedge (Vismodegib)
  • RG7420/XL518 (MEK Inhibitor)
  • RG7459 (IAP Antagonist)
  • Genentech - Omnitarg (Pertuzumab)
  • RG7321/GDC-0941 (P13 Kinase Inhibitor)
  • Genentech - Erlotinib/Pertuzumab Combination Therapy
  • Genentech - ABT-869 (VEGFR Kinase Inhibitor)
  • Genentech - Avastin/Sutent Combination Therapy (Bevacizumab/Sunitinib)
  • Genentech - Dulanermin (rhApo2L/TRAIL)
  • Genentech - Apomab (Proapoptotic Receptor Agonist)
  • Navitoclax/RG7433/Genentech ABT-263 (Bcl-2 Antagonist)
  • Genentech - Avastin (Bevacizumab)/Tarceva (Erlotinib HCl)
  • Genentech - MetMAb
  • Genentech - Zelboraf (Vemurafenib)/Formerly RG7204/PLX4032 (BRAF Kinase Inhibitor)
  • RG7594 (Monoclonal Antibody)
  • RG7593 (Anti-CD22 Monoclonal Antibody)
  • RG7440 (AKT Inhibitor)
  • RG7422 (PI3 Kinase Inhibitor)
  • RG7421 (MEK (Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase) Inhibitor)
  • RG7414 (Anti-EGFL7(Epidermal Growth Factor Like Domain Multiple 7))
  • RG7347 (Anti-NRP1)
  • RG7334 (Anti-PLGF)
  • RG7304 (Raf/MEK Dual Inhibitor)
  • RG7256 (BRAF Kinase Inhibitor)
  • RG7167 (CIF/MEK Inhibitor)
  • RG7160 (EGFR Monoclonal Antibody)
  • RG7112 (MDM2 Antagonist)
  • RG3484 (HPV16 Vaccine)
  • Anti-Glypican Monoclonal Antibody
  • Topoisomerase I Inhibitor
  • RG7444 (Anti-FGFR3 Monoclonal Antibody)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Buyer Products:

  • Poly ADP-Ribose Polymerase Inhibitor (PARP)
  • Oncofetal protein 5T4
  • CME-548
  • PRA-027
  • PF-5212374/TRU-015 (Small Modular Immunopharmaceutical (SMIP))
  • SKI-015

Target Products:

  • Elomotecan/BN80927 (Topoisomerase I/II Inhibitor)
Respiratory System/Thoracic
Lung Cancer
Non Small Cell Lung Cancer (NSCLC)
EGFR-TK Inhibitors/Monoclonal Antibodies
Therapeutics that treat lung cancer by blocking the tyrosine kinase enzyme and by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Genentech - Avastin (Bevacizumab)/Tarceva (Erlotinib HCl)
 
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the tyrosine kinase enzyme by switching off the signals from the epidermal growth factor receptors.

Target Products:

  • Genetech - Tarceva (Erlotinib)
 
Monoclonal Antibodies
Therapeutics that treat lung cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Dacomitinib/Formerly PF-00299804 (pan-HER Inhibitor)

Target Products:

  • Avastin (Bevacizumab)
  • Genentech - MetMAb
Toll-Like Receptor Agonists
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by stimulating the immune system.

Buyer Products:

  • PF-3512676 (Promune)
 
Topoisomerase I Inhibitors
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by inhibit a specific enzyme needed for the replication and transcription of DNA.

Buyer Products:

  • Camptosar (Irinotecan Hydrochloride)
 
Tyrosine Kinase Inhibitors
Therapeutics that treat lung cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • XALKORI (Crizotinib)/Formerly PF-2341066
 
Urology
Kidney Cancer (Renal Cell Carcinoma)
Metastatic
Mammalian Target Of Rapamycin (mTOR) Inhibitors
Therapeutics that treat and manage renal cancers that have spread beyond their original tumor site by inhibiting signals required for cell cycle progression, cell growth, and proliferation.

Buyer Products:

  • Torisel (Temsirolimus)
 
Monoclonal Antibodies
Therapeutics that treat kidney cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
 
Tyrosine Kinase Inhibitors
Therapeutics that treat kidney cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Inlyta (Axitinib)
  • Sutent (Sunitinib Malate)/Formerly SU-011248
 
Wilm`s Tumor (Nephroblastoma)  
Topoisomerase II Inhibitors
Therapeutics that treat and manage tumors of the kidney by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Ovarian Cancer
Adenocarcinoma
Monoclonal Antibodies
Therapeutics that treat ovarian cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • R1549/Formerly Pemtumomab
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancer of cells lining the ovary by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Metastatic  
Monoclonal Antibodies
Therapeutics that treat and manage ovarian cancers that have spread beyond their original tumor site by binding to specific structures on the surface of the tumor, eliciting a reaction which results in tumor cell death.

Target Products:

  • Avastin (Bevacizumab)
 
Prostate Cancer  
Localized  
Estrogens
Therapeutics that treat and manage primary tumors of the prostate gland by inhibiting the secretion of luteinizing hormone and affecting the testes so as to decrease serum concentrations of testosterone.

Buyer Products:

  • Emcyt (Estramustine Phosphate)
 
Palliative Agents  
Estrogens
Therapeutics that treat and manage prostate cancer by inhibiting the secretion of luteinizing hormone and affecting the testes so as to decrease serum concentrations of testosterone but are not curative.

Buyer Products:

  • Menest (Esterified Estrogens Tablets)
  • Premarin/Low-Dosage Premarin (Conjugated Estrogens)
 
Gonadotropin Releasing Hormone (GnRH) Antagonists
Therapeutics that treat and manage primary tumors of the prostate gland by blocking the action of gonadotropin releasing hormone and thus decreasing levels of testosterone.

Buyer Products:

  • Trelstar Depot (Triptorelin Pamoate)
 
Urinary Bladder Cancer  
Transitional Cell Carcinoma  
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers arising from the lining of the bladder by inhibiting a specific enzyme needed for transcription and replication of DNA.

Buyer Products:

  • Adriamycin (Doxorubicin Hydrochloride)
 
Ophthalmology
Degenerative Disorders
Edema  
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular edema by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Target Products:

  • Lucentis (Ranibizumab)
 
Glaucoma  
Prostanoid Selective FP Receptor Agonists
Therapeutics that increase the outflow of fluid of the eye.

Buyer Products:

  • Xalatan (Latanoprost)
 
Irritation/Inflammation  
Antibacterial Agents (Antibiotics)
Therapeutics that treat infections by inhibiting bacterial replication.

Buyer Products:

  • Neosporin Ophthalmic (Neomycin Sulfate B/Polymyxin Sulfate B/Gramicidin) Ointment/Solution Sterile
 
Antibacterial Agents/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat infections by inhibiting bacterial replication as well as prevent cells that cause inflammation from adhering to the inflammation site.

Buyer Products:

  • Cortisporin Ophthalmic (Neomycin/Polymyxin B Sulfates/Bacitracin Zinc/Hydrocortisone) Ointment/Suspension Sterile
 
Tetracyclines/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat irritation and inflammation of the eye by inhibiting the growth of bacteria and by preventing the accumulation of inflammatory cells.

Buyer Products:

  • Terra-Cortril (Oxytetracycline Hydrochloride/Hydrocortisone Acetate)
 
Macular Degeneration (AMD)
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular degeneration by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Buyer Products:

  • Macugen (Pegaptanib Sodium)

Target Products:

  • Lucentis (Ranibizumab)
Retinitis  
AIDS-Related Cytomegalovirus (CMV) Retinitis  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Ocular Hypertension  
Prostanoid Selective FP Receptor Agonists
Therapeutics that treat a condition characterized by increased pressure in the fluid of the eye by increasing the outflow of fluid of the eye.

Buyer Products:

  • Xalatan (Latanoprost)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of eye disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PF-4523655
  • PF-4382923
  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)
  • PF-4217329

Target Products:

  • Lucentis (Ranibizumab)
  • RG7417 (Anti-Factor D Monoclonal Antibody)
Pain Management
Anesthesia
General (Systemic)
Adjunctive  
Barbiturates
Therapeutics that result in anesthesia due to a general sedative effect by enhancing the response to gamma aminobutyric acid and decrease excitability by directly suppressing conduction in the brain.

Buyer Products:

  • Brevital Sodium C-IV (Methohexital Sodium)
 
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that result in anesthesia by preventing the uptake of gamma-aminobutyric acid, which prevent nerve activation.

Buyer Products:

  • Lyrica (Pregabalin)
 
Primary  
Barbiturates
Therapeutics that result in anesthesia due to a general sedative effect by enhancing the response to gamma aminobutyric acid and decrease excitability by directly suppressing conduction in the brain.

Buyer Products:

  • Brevital Sodium C-IV (Methohexital Sodium)
 
Reversal  
Gamma-Aminobutyric Acid (GABA) Receptor Antagonists
Therapeutics that reverse general anesthesia by competitively inhibiting benzodiapizines at the GABA receptors, thus reducing their effect and reversing the anesthesia.

Target Products:

  • Romazicon (Flumazenil)
 
Narcotics  
Opioids
Therapeutics that treat pain by binding to certain nervous system receptors which alter both the perception of pain as well as the emotional response to pain.

Buyer Products:

  • Remoxy (Time-Release Oxycodone)
  • Avinza CII (Morphine Sulfate ER Capsules)
  • Alpharma Embeda (Abuse Resistant Morphine Sulphate/Naltrexone)
  • OXECTA /Formerly Acurox (Oxycodone HCl)
 
Opioids/Opioid Antagonists
Therapeutics that treat pain by binding to certain nervous system receptors which alter both the perception of pain as well as the emotional response to pain, and at the same time reduce the likelihood of physical dependence or addiction.

Buyer Products:

  • Oxycodone Hcl/Naltrexone Hcl Extended Release Capsule
 
Non-Narcotics
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat pain by inhibiting the reuptake of GABA, which increases the levels of GABA in the synapses.

Buyer Products:

  • Lyrica (Pregabalin)
  • Neurontin (Gabapentin)
 
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain by specifically inhibiting the action of cyclooxygenase-2.

Buyer Products:

  • Celebrex (Celecoxib)
  • Bextra (Valdecoxib)
  • Dynastat (Parecoxib Sodium Injection)
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Alpharma Flector Patch (Diclofenac Epolamine)
  • Advil (Ibuprofen)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  • Aleve (Naproxen Sodium)
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Decongestants
Therapeutic combinations that produce insensibility or numbness through the inhibition of prostoglandins while also preventing nasal decongestion.

Target Products:

  • Aleve Cold & Sinus (Naproxen/Pseudoephedrine)
 
Skeletal Muscle Relaxing Agents
Therapeutics that treat pain by depressing specific synaptic reflexes preferentially.

Buyer Products:

  • Skelaxin (Metaxalone)
 
Skeletal Muscle Relaxing Agents/Analgesics
Therapeutics that treat pain by depressing specific synaptic reflexes preferentially, as well as prevent inflammation by inhibiting the action of prostaglandins.

Buyer Products:

  • Equagesic (Meprobamate/Aspirin)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of pain in early stages of clinical research where human subject is involved.

Buyer Products:

  • Alpharma ELADUR (TRANSDUR-Bupivacaine)
  • Nav1.7 Compound (Sodium Ion Channel Modulator)
  • Icagen, Inc. - Nav1.7 Compound (Sodium Ion Channel Modulator)
  • Icagen, Inc. - ICA-105665 (Potassium Channel Activator Compound)
  • Tanezumab
  • ADL5859/PF-04856880 (Delta Opioid Receptor Agonist)
  • Hydrocodone NT (Hydrocodone/Naltrexone)
  • PF-4457845
  • PF-4531083
  • ORADUR Abuse-Resistant Opioid
  • T-62
  • PF-4856881
  • PF-2393296
  • CE-224535

Target Products:

  • Bondronat (Ibandronate)
  • EVT 101 (NMDA Receptor Antagonist)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of pain in very early stages of research where no human subject is involved.

Buyer Products:

  • Acuracet (Aversion Oxycodone/Acetaminophen)
  • ADL5747/PF-04856881 (Delta Opioid Receptor Agonist)
  • Vycavert (Aversion Hydrocodone Bitartrate/Acetaminophen)
  • PTI-721
 
Respiratory System
Lower Respiratory Tract Disorders (Lung Disorders)
Asthma
Acute Treatments  
Bronchodilators  
Alpha Adrenergic Receptor Agonists/Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Adrenalin Chloride Solution (Epinephrine)
  • Primatene Mist (Epinephrine)
 
Prophylactic Treatments
Mast Cell Stabilizers
Therapeutics that treat asthma by inhibiting mast cell degranulation.

Buyer Products:

  • Intal HFA (Cromolyn Sodium)
  • Tilade (Nedocromil Sodium)
 
Monoclonal Antibodies
Therapeutics that treat asthma with monoclonal antibodies.

Target Products:

  • Xolair (Omalizumab)
 
Bronchitis  
Complications  
Bacterial Infections  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Septra (Sulfamethoxazole/Trimethoprim) IV Infusion/Tablets/Suspension
 
Bronchospasm  
Bronchodilators  
Alpha Adrenergic Receptor Agonists/Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Adrenalin Chloride Solution (Epinephrine)
 
Chronic Obstructive Pulmonary Disease (COPD)  
Prophylactic Treatments  
Anticholinergic Agents
Therapeutics that block the actions of choline and other cholinergic agents.

Buyer Products:

  • Spiriva (Tiotropium Bromide)
 
Cystic Fibrosis (CF)  
Recombinant Human Deoxyribonuclease I
Therapeutics that relieve symptoms of cystic fibrosis by hydrolyzing the DNA in the sputum of cystic fibrosis patients thus reducing viscosity of the secretions and aiding lung function.

Target Products:

  • Genentech - Pulmozyme (Dornase Alfa)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Icagen, Inc. - Senicapoc/Formerly ICA-17043 (Potassium Channel Blocking Agent)
  • PF-3635659
  • PF-3654764
  • Enbrel/Enbrel Once-Weekly (Etanercept)
  • PF-3893787
  • PF-4191834
  • PF-3526299
  • PH-797804
  • PF-610355

Target Products:

  • Ro 27-2411 (Integrin Antagonist)
  • RG667/Palovarotene (Nuclear Receptor)
  • RG7449 (Anti-M1 Prime Monoclonal Antibody)
  • RG7185 (CRTH2 Antagonist)
  • R1295 (Integrin Antagonist)
  • Lebrikizumab/RG3637 (Humanized Anti-IL13 Antibody)
  • RG4930 (Anti-OX40L Monoclonal Antibody)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Cystic Fibrosis Program
 
Upper Respiratory Tract Disorders  
Coughs/Colds  
Anticholinergic Agents/Opioids
Therapeutics that treat coughs and colds by relieving pain and fever as well as suppressing cough.

Buyer Products:

  • Tussigon Tablets CIII (Hydrocodone Bitartrate/Homatropine Methylbromide)
 
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Alavert Disintegrating Tablets (Loratadine)
 
Antihistamines/Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by suppressing inflammation, reducing mucous build up, relieving or preventing coughs, relieving pain, and reducing fever.

Buyer Products:

  • Robitussin Allergy And Cough Syrup
 
Antitussives
Therapeutics that relieve or prevent coughs.

Buyer Products:

  • Robitussin Maximum Strength Cough Suppressant (Dextromethorphan Hydrobromide)
 
Decongestants
Therapeutics that treat coughs and colds by reducing mucous build up.

Buyer Products:

  • Dristan (Oxymetazoline)
 
Decongestants/Analgesics
Therapeutics that treat coughs and colds by reducing mucous build up and relieving pain.

Buyer Products:

  • Advil Cold & Sinus (Ibuprofen/Pseudoephedrine)
 
Decongestants/Antitussives
Therapeutics that treat coughs and colds by reducing mucous build up and suppressing the cough.

Buyer Products:

  • Nucofed Capsules/Syrup CIII (Codeine Phosphate/Pseudoephedrine Hydrochloride)
  • Robitussin Maximum Strength Cough & Cold (Dextromethorphan Hydrobromide / Pseudoephedrine Hydrochloride)
 
Decongestants/Antitussives/Expectorants
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing coughs and helping in the ejection of the mucous.

Buyer Products:

  • Nucofed Expectorant/Pediatric Expectorant (Codeine Phosphate/Pseudoephedrine Hydrochloride/Guaifenesin)
  • Robitussin Cold And Cough (Guaifenesin / Pseudoephedrine Hydrochloride / Dextromethorphan Hydrobromide)
  • Robitussin CF (Guaifenesin / Phenylpropanolamine Hydrochloride / Dextromethorphan Hydrobromide)
  • Robitussin Cough And Congestion Syrup (Guanifenesin/Dextromethorphan)
  • Robitussin Allergy And Cough Syrup
 
Decongestants/Antitussives/Expectorants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing the cough, helping in the ejection of mucous and helping relieve fever and pain.

Buyer Products:

  • Robitussin Cold Cough & Flu (Acetominophen / Guaifenesin / Pseudoephedrine Hydrochloride / Dextromethorphan Hydrobromide)
 
Expectorants
Therapeutics that treat coughs and colds by helping in the ejection of mucous.

Buyer Products:

  • Robitussin (Guaifenesin)
 
Surgery
Cardiovascular System  
Complications  
Peripheral Arterial Occlusion  
Thrombolytic Agents
Therapeutics that treat diseases of the blood vessels outside the heart by dissolving blood clots.

Target Products:

  • Cathflo Activase (Alteplase)
 
Digestive System  
Post-Operative Ileus/Constipation  
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Relistor (Subcutaneous Methylnaltrexone Bromide)
 
General  
Complications  
Hemorrhage  
Coagulating Agents (Coagulants)
Therapeutics that treat bleeding during a surgical procedure by promoting blood clotting.

Buyer Products:

  • Thrombin JMI
 
Musculoskeletal System  
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by blocking an enzyme involved in the clotting process.

Buyer Products:

  • Fragmin (Dalteparin Sodium)
 
Factor Xa Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Eliquis (Apixaban)
 
Neurology  
Seizures  
Sodium Channel Modulators
Therapeutics that treat seizures by controlling the entrance of sodium into the nerve cells.

Buyer Products:

  • Cerebyx (Fosphenytoin Sodium)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of surgical complications in early stages of clinical research where human subject is involved.

Buyer Products:

  • Revatio (Sildenafil Citrate)
 
Toxicology
Animal Poisoning  
Snakes  
Immunoglobulins
Therapeutics that treat snake bites with target specific proteins that neutralize the poison.

Buyer Products:

  • Antivenin (Micrurus Fulvius)
  • Antivenin (Crotalidae) Polyvalent
 
Chemical Poisoning  
Anticholinergic Agents  
Acetylcholinesterase Inhibitors
Therapeutics that are meant to treat toxic overdose of drugs with anticholinergic properties by inhibiting the action of acetylcholinesterase.

Buyer Products:

  • Protopam Chloride (Pralidoxime Chloride for Injection)
 
Cyanide  
Chelating Agents
Therapeutics that form chemical complexes with cyanide and are subsequently excreted.

Buyer Products:

  • Cyanokit (Hydroxocobalamin For Injection)
 
Nerve Gas  
Anticholinergic Agents
Therapeutics that treat toxicity due to nerve agent/gas by antagonizing the muscarine-like actions of acetylcholine and other choline esters.

Buyer Products:

  • Meridian Medical Technologies Duodote (Atropine/Pralidoxime Chloride Injection)
  • Meridian Medical Technologies AtroPen (Atropine)
 
Substance Abuse
Withdrawal
Alcohol  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Target Products:

  • Valium (Diazepam)
 
Nicotine (Smoking Cessation)  
Nicotinic Receptor Agonists
Therapeutics that treat nicotine withdrawal by activating nicotine receptors thus reducing cravings for nicotine.

Buyer Products:

  • Chantix (Varenicline)
 
Transplantation
Bone Marrow  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Cytovene (Ganciclovir)
 
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics containing biological proteins that stimulate the formation of certain white blood cells called granulocytes.

Target Products:

  • Neutrogin (Granulocyte Colony Stimulating Factor)
 
Heart  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that help manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • CellCept (Mycophenolate Mofetil)
 
Hepatic (Liver)
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Rejection Prophylaxis
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • Rapamune (Sirolimus)

Target Products:

  • CellCept (Mycophenolate Mofetil)
Lung  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Pancreas  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the management of rejection and infection in early stages of clinical research where human subject is involved.

Buyer Products:

  • Tofacitinib/Formerly Tasocitinib/CP-690550 (JAK-3 Inhibitor)

Target Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
Renal (Kidney)
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Rejection Prophylaxis
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • Rapamune (Sirolimus)

Target Products:

  • CellCept (Mycophenolate Mofetil)
Monoclonal Antibodies
Protein-based therapeutics that target specific substances like proteins.

Target Products:

  • Zenapax (Daclizumab)
 
Urology
Male Genital Disorders  
Penile  
Erectile Dysfunction (Impotence)  
Phosphodiesterase Type 5 Inhibitors (PDE-5 Inhibitors)
Therapeutics that inhibit the breakdown of phosphodiesters thereby increasing levels of Nitric Oxide which help in dilating the blood vessels in the penis.

Buyer Products:

  • Viagra (Sildenafil Citrate)
 
Vasodilatory Agents
Therapeutics that increase blood flow in the penis by dilating blood vessels.

Buyer Products:

  • Caverject (Alprostadil)
 
Peyronie`s Disease  
Antifibrotic Agents
Therapeutics that treat fibrosis by increasing oxygen utilization at the tissue level, which in turn helps in the degradation of serotonin. A causal relationship is thought to exist between fibrosis and increased serotonin levels.

Buyer Products:

  • Xiapex (Collagenase Clostridium Histolyticum)
 
Prostate  
Benign Prostate Hyperplasia (BPH)  
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that increase blood flow by acting on the alpha adrenergic receptors thus causing the smooth muscle in the prostate to relax and decreasing the constriction on the urinary tract.

Buyer Products:

  • Cardura XL (Doxazosin Mesylate)
  • Cardura (Doxazosin Mesylate)
 
Testicular  
Abnormal Puberty  
Delayed  
Androgens
Therapeutics that treat puberty disorders by providing male sex hormones.

Buyer Products:

  • Halotestin (Fluoxymesterone)
 
Hypogonadism  
Androgens
Therapeutics that treat hypogonadism by providing male sex hormones.

Buyer Products:

  • Depo-Testosterone (Testosterone)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PD-299685
  • PF-3882845
  • PF-3274167

Target Products:

  • PLX5568 (Raf Kinase Inhibitor)
  • R1484 (GPCR Modulator)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1437 (GPCR Antagonist)
 
Urological Disorders
Bladder  
Urinary Frequency/Urge Incontinence  
Muscarinic Receptor Antagonists
Therapeutics that treat COPD by blocking the action of choline and other cholinergic agents from binding to the muscarinic receptor.

Buyer Products:

  • Detrol LA (Tolterodine Tartrate)
  • Toviaz (Fesoterodine Fumarate Extended Release)
  • Detrol (Tolterodine Tartrate)
 
Kidney (Renal)
Chronic Renal Failure (CRF)
Complications
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat the condition resulting from the scarcity of red blood cells by inducing the production of red blood cells.

Target Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
 
Edema
Loop Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine.

Target Products:

  • Demadex (Toresmide)
 
Potassium Sparing Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine without striping the body of potassium.

Buyer Products:

  • Aldactone (Spironolactone)
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Buyer Products:

  • Aldactazide (Spironolactone/Hydrochlorothiazide)
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium, potassium ions, and water in urine.

Buyer Products:

  • Thalitone (Chlorthalidone)
  • Renese (Polythiazide)
 
Renal Insufficiency  
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that delay or treat kidney disease by inhibiting the renin-angiotensin system.

Buyer Products:

  • King Phramaceuticals, Inc. - Altace (Ramipril)
 
Weight Management
Obesity
Lipase Inhibitors
Therapeutics that reduce the absorption of fat by inhibiting production of lipase, which is an enzyme that helps breaking down fat in the food.

Target Products:

  • Xenical (Orlistat)
 
Prader-Willi Syndrome  
Growth Hormones
Therapeutics that treat a rare genetic disorder with a number of symptoms, the most significant of which is obesity, by supplying the body with growth hormones.

Buyer Products:

  • Genotropin (Recombinant Somatropin (Human Growth Hormone))
 
Sympathomimetic Agents
Therapeutics that suppress appetite by stimulating the adrenergic receptors and produce adrenergic chemicals.

Buyer Products:

  • Didrex (Denzphetamine Hydrochloride)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PF-2575799
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in very early stages of research where no human subject is involved.

Target Products:

  • MAR701 (Peptide Therapy)
 
Wound Management
Bone Fractures  
Growth Factors  
Recombinant Human Bone Morphogenetic Proteins (rhBMP)
Therapeutics that promote healing of a broken bone by promoting the proliferation of bone cells.

Buyer Products:

  • Recombinant Human Bone Morphogenetic Protein (rhBMP-2)
 
Burns  
Complications  
Infections  
Antibacterial Agents (Antibiotics)  
Sulfonamides
Therapeutics that treat bacterial infections in injuries caused by fire or excessive heat by inhibiting folic acid synthesis.

Buyer Products:

  • Silvadene (Silver Sulfadiazine)
 
Antifungal Agents  
Sulfonamides
Therapeutics that treat fungal infections in injuries caused by fire or excessive heat by inhibiting folic acid synthesis.

Buyer Products:

  • Silvadene (Silver Sulfadiazine)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of wounds in early stages of clinical research where human subject is involved.

Buyer Products:

  • Excaliard Pharmaceuticals, Inc. - EXC 001 (Anti-CTGF Antisense Oligonucleotide)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of wounds in very early stages of research where no human subject is involved.

Target Products:

  • Vascular Endothelial Growth Factor
 
Healthcare Services  
Patient Care  
Ambulatory/Outpatient  
Diagnostic  
Clinical Laboratories  
Pathology
Similar to routine clinical lab services, pathology services are provided by licensed medical physicians and therefore may involve the additional role of diagnosis and consultation of results with the referring physician.

Target Products:

  • Quantitative Diagnostics Laboratories, Inc. (QDL)
 
Specialized
Specialized laboratory testing services involving highly specialized equipment, personnel, and procedures.

Target Products:

  • Verum Diagnostica GmbH
 
Medical Devices
Cardiology  
Diagnostic  
Monitoring  
Monitors  
Stress/Exercise Test
Instruments used to evaluate the cardiopulmonary system during exercise.

Buyer Products:

  • CorVue (Binodenoson Injection)
 
Clinical Diagnostics
Chemistry
Analyzers  
Clinical Chemistry
Analyzers used to quantify various chemicals in blood plasma or serum samples. Blood gas and protein analyzers are included.

Target Products:

  • Roche Diagnostics - Roche/Hitachi 902/912
  • Roche Diagnostics - Cobas 8000 Modular Analyser Series
  • Roche Diagnostics - Cobas Integra Series
  • Roche Diagnostics - AVL Compact 1-3
  • Roche Diagnostics - AVL 9180 Series
  • Roche Diagnostics - AVL 988 Series
  • Roche Diagnostics - OMNI Series
  • Roche Diagnostics - Reflotron Series
 
Urinalysis
Analyzers used to perform chemical, physical and microscopic analysis of urine.

Target Products:

  • Roche Diagnostics - Miditron M
  • Roche Diagnostics - Urisys 2400
  • Roche Diagnostics - Urisys 1100
  • Roche Diagnostics - Miditron Junior II
 
Home Testing
Glucose Testing/Diabetes Monitoring  
Invasive  
Continuous Analysis
Glucose test devices which measure patient glucose levels on a continual basis.

Target Products:

  • Roche Diagnostics - GlucOnline Microdialysis System
 
Random Analysis
Glucose test devices which measure patient glucose levels on a random basis.

Target Products:

  • Roche Diagnostics - Accu-Chek Complete/Sensor Complete Meter
  • Roche Diagnostics - Accu-Chek Advantage/Advantage II/Sensor Meter
  • Roche Diagnostics - Accu-Chek Active Meter
  • Roche Diagnostics - Accu-Chek Aviva
  • Roche Diagnostics - Accu-Check Nano SmartView
  • Roche Diagnostics - Accu-Chek Voicemate
  • Roche Diagnostics - Accu-Chek Mobile
  • Roche Diagnostics - Accu-Chek Combo
  • Roche Diagnostics - Accu-Chek Simplicity
  • Roche Diagnostics - Accu-Chek Inform System
  • Roche Diagnostics - AccuData GTS/AccuData HDM
  • Roche Diagnostics - Accu-Chek Compact Meter
 
Test Strips
Specific glucose test devices used with glucose monitors.

Target Products:

  • Roche Diagnostics - Glucotrend Strips
  • Roche Diagnostics - Accu-Chek Compact Test Drums
  • Roche Diagnostics - Accu-Chek Comfort Curve/Sensor Comfort/Advantage Comfort/Advantage II Test Strips
  • Roche Diagnostics - Accu-Chek Active Test Strips
  • Roche Diagnostics - Accu-Chek Advantage Test Strips
 
Urine  
Pregnancy
Home pregnancy testing kits.

Buyer Products:

  • Parke-Davis/ e.p.t.
 
Point of Care Testing  
Critical Care Analysis  
Analyzers
Chemistry analyzers which may be used for the chemical analysis of body fluids and designed for use at the bedside during the course of patient care.

Target Products:

  • Roche Diagnostics - BioVeris Elecsys System
  • Roche Diagnostics - Accutrend System
 
Test Cartridges
Specific analyte test devices used in conjunction with critical care chemistry analyzers.

Target Products:

  • Roche Diagnostics - BioVeris Elecsys System
 
Kits  
Cardiac
Test kits used to aid in the diagnosis of heart conditions.

Target Products:

  • Roche Diagnostics - Cobas h 232 System
  • Roche Diagnostics - Cardiac D-Dimer
 
Reagents  
Calibrators
Specific standards of known concentration for analytes that are used to define test performance of chemistry analyzers, including blood gas analyzers and other routine analyte analyzers.

Target Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
 
Controls
Materials with known concentrations used to verify the accuracy of test systems, including blood gas system, routine system, microbiology system, and other specialized systems.

Target Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
 
Test Kits  
Genetic/Molecular Diagnostics  
Disease Diagnosis  
Infectious Diseases  
Automated Analyzers
Analyzers designed for genetic probe assays to detect and quantitate microorganisms.

Target Products:

  • Roche Diagnostics - COBAS AmpliPrep System
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
  • Roche Diagnostics - COBAS AMPLICOR Analyser
 
Reagents  
Bacterial  
Tuberculosis
Genetic probe for detection and/or quantitation of Mycobacterium tuberculosis.

Target Products:

  • Roche Diagnostics - COBAS AMPLICOR MTB Test/AMPLICOR MTB Test
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium Intracellular (MIN) Test/AMPLICOR MIN Test
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
 
Viral  
Cytomegalovirus
Genetic probe for detection and/or quantitation of Cytomegalovirus.

Target Products:

  • Roche Diagnostics - AMPLICOR CMV Test
  • Roche Diagnostics - COBAS AMPLICOR CMV Monitor Test
  • Roche Diagnostics - BioVeris NucliSens/NASBA QR
 
Hepatitis B Virus
Genetic probes for detection and/or quantitation of HBV.

Target Products:

  • Roche Diagnostics - COBAS AmpliScreen HBV Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
  • Roche Diagnostics - COBAS TaqMan HBV Test
 
Hepatitis C Virus
Genetic probes for detection and/or quantitation of HCV.

Target Products:

  • Roche Diagnostics - COBAS AMPLICOR HCV Test/AMPLICOR HCV Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
  • Roche Diagnostics - COBAS AmpliScreen HCV Test
  • Roche Diagnostics - COBAS TaqMan HCV Test
  • Roche Diagnostics - PCR COBAS TaqMan HCV Test
  • Roche Diagnostics - COBAS AMPLICOR HCV Monitor Test/AMPLICOR HCV Monitor Test
 
Human Immunodeficiency Virus (HIV)
Genetic probes for detection and quantification of HIV.

Target Products:

  • Roche Diagnostics - AmpliPrep/COBAS TaqMan HIV-1 Test
  • Roche Diagnostics - COBAS AmpliScreen HIV-1 Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
 
Human Papilloma Virus
Genetic probes for the detection of HPV.

Target Products:

  • Roche Diagnostics - Cobas HPV Test
  • Roche Diagnostics - Digene Hybrid Capture II HPV Test
  • Roche Diagnostics - Linear Array HPV Genotyping Test
  • Roche Diagnostics - Amplicor HPV Test
 
Influenza (Flu)
Genetic probes for detection and/or quantitation of Influenza (Flu) virus.

Target Products:

  • Roche Diagnostics - Influenza A/H1N1 Detection Set
 
West Nile Virus
Genetic probes for detection and/or quantitation of West Nile Virus.

Target Products:

  • Roche Diagnostics - TaqScreen West Nile Virus Test
 
Oncology  
Colorectal Cancer/Colon Cancer
Tests designed to diagnose colorectal cancer/colon cancer through genetic detection and analysis.

Target Products:

  • Roche Diagnostics - hemo FEC
 
Pharmacogenetic
Tests designed to determine patients' reactions to specific medications based on their genes.

Target Products:

  • Roche Diagnostics - AmpliChip CYP450 Test
  • Roche Diagnostics - Ventana Medical Systems INFORM HER2 SISH DNA Probe Assay
 
Urinalysis
Test kits used to perform chemical and physical analysis of urine.

Target Products:

  • Roche Diagnostics - Chemstrip Series
 
Hematology/Hemostasis  
Hematology  
Analyzers  
Multiple Parameter
Hematology analyzers designed for use in determining multiple hematological parameters in a clinical setting.

Target Products:

  • Roche Diagnostics - Cobas b121 System
  • Roche Diagnostics - Cobas b 221 System
 
Hemostasis  
Analyzers  
Automated
Automated coagulation analyzers.

Target Products:

  • Roche Diagnostics - Stago Systems
  • Roche Diagnostics - Coasys Plus C
 
Reagents  
Test Kits  
Thrombin/Thromboplastin
Test kits used to perform thrombin time, prothrombin time, and activated partial thromboplastin time assays.

Target Products:

  • Roche Diagnostics - CoaguChek Series
 
Histology  
Imaging Systems  
Cytopathology
Systems designed to enhance microscopic visualization of human cells through camera, video or digital viewing processes.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso System for HER2 (4B5)
  • Roche Diagnostics - Ventana Companion Algorithm p53 (DO-7) Image Analysis Application
  • Roche Diagnostics - Ventana Companion Algorithm Progesterone Receptor (PR) (1E2) Image Analysis Application
  • Roche Diagnostics - Ventana Image Analysis System (VIAS)
 
Processing Equipment  
Slide Processing
Slide processing equipment including slide labelers, slide makers, and immunohistochemistry and in-situi hybridization slide stainers.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems EBAR SLS Slide Labeling System
  • Roche Diagnostics - Ventana Medical Systems Discovery XT System
  • Roche Diagnostics - Ventana Medical Systems BenchMark LT/ XT System
  • Roche Diagnostics - Ventana Medical Systems Automated Staining Systems
  • Roche Diagnostics - Ventana Medical Systems BenchMark ULTRA System With Ultimate Reagent Access (URA)
  • Roche Diagnostics - Ventana Medical Systems iScan Coreo Au
 
Tissue Processing
Instrument used for the automated processing and embedding of tissue samples.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Tissue Processor
 
Reagents  
Biomolecular Stains
Vital reagents used in the staining of tissue in order to view microscopically for pathology.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems PATHWAY c-KIT
  • Roche Diagnostics - Ventana Medical Systems Immunohistochemistry (IHC) Detection Systems And Ancillary Products
 
Kits  
DNA Probes
Staining kits which utilize DNA probes to mark specific cells for staining.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Inform ISH/FISH Probes
 
In-Situ Hybridization (ISH)
Staining kits which utilize In-Situ hybridization techniques to mark specific cells for staining.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
 
Preparation/Preservation
Reagents used for preservation of tissues and preparation of tissues for analysis.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Immunohistochemistry (IHC) Detection Systems And Ancillary Products
 
Immunoassays
Analyzers  
Accessories
Reagents and equipment used to facilitate immunoassay testing.

Target Products:

  • Roche Diagnostics - Elecsys Anti-HBc IgM Assay
 
Multiple Assay
Immunoassay analyzer designed to perform multiple assays over multiple modalities.

Target Products:

  • Roche Diagnostics - Cobas 8000 Modular Analyser Series
  • Roche Diagnostics - BioVeris Elecsys System
  • Roche Diagnostics - BioVeris E170
  • Roche Diagnostics - BioVeris Picolumi
  • Roche Diagnostics - Cobas Core II
 
Reagents
Calibrators
Specific standards of known concentration for analytes that are used to define and or measure test performance of immunoassay test kits and systems.

Target Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
 
Controls
Reagents used to verify the function and reliability of immunoassay test kits and systems.

Target Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
 
Test Kits
Allergy
Immunassay kits used to detect and quantitate allergy associated analytes.

Buyer Products:

  • Pharmacia CAP System
 
Cardiovascular System  
Cardiac
Immunoassay kits used to screen, diagnose or monitor cardiac conditions.

Target Products:

  • Roche Diagnostics - TROPT Sensitive
  • NT-proBNP
  • Roche Diagnostics - Cardiac Reader
 
Infectious Diseases
Bacterial
Immunoassay kits which test for the presence of infectious diseases or previous infection caused by bacteria.

Buyer Products:

  • Aplisol (Tuberculin Purified Protein Derivative)

Target Products:

  • Ventana Anti-Helicobacter Pylori (SP48) Rabbit Monoclonal Primary Antibody
  • Roche Diagnostics - Amplicor M. tuberculosis Test
  • Roche Diagnostics - COBAS AMPLICOR CT/NG Test/AMPLICOR CT/NG Test
  • Cobas 4800 CT/NG Test
Viral
Immunoassay kits which test for the presence of infectious disease or previous infection caused by viruses.

Target Products:

  • IgM Antibody To Hepatitis B Core Antigen (Anti-HBc IgM)
  • Roche Molecular Systems - Cobas HPV Test
  • Roche Diagnostics - AMPLICOR HIV-1 Monitor Test
  • Roche Diagnostics - COBAS Amplicor HIV-1 Test
 
Oncology  
Breast Cancer
Diagnostic assay used to detect specific breast tumor or cancer markers.

Target Products:

  • BCM 18 (Breast Cancer Marker)
  • Roche Diagnostics - Ventana Medical Systems PATHWAY HER-2/neu (4B5) Rabbit Monoclonal Antibody
 
Cervical Cancer
Diagnostic assay used to detect specific cervical tumor or cancer markers.

Target Products:

  • mtm Laboratories AG - CINtec Histology Kit
 
Digestive System Cancer
Diagnostic assay used to detect specific digestive system cancer markers.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems VentanaDx c-KIT
 
Multiple Tumor
Diagnostic assay used to detect markers associated with multiple cancer types.

Target Products:

  • Roche Molecular Diagnostics - Cobas 4800 BRAF V600 Mutation Test
  • Roche Diagnostics - Cobas Core Reagent Series
 
Opthalmology
Immunoassay kits used to quantify markers associated with opthalmic diseases.

Target Products:

  • Roche Diagnostics - OnTrak TesTcard 9
  • Roche Diagnostics - Cobas Integra Reagents Series
 
Toxicology/Drugs Of Abuse  
Drugs Of Abuse
Immunoassay test kits which test for drugs of abuse in body fluids.

Target Products:

  • Roche Diagnostics - OnTrak TesTcard 9
  • Roche Diagnostics - Cobas Integra Reagents Series
 
Therapeutic Drugs
Immunoassay test kits which measure levels of therapeutic drugs in body fluids.

Target Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
 
Specimen Collection  
Blood  
Capillary  
Lancets
Sharps type of device used to puncture the skin in order to collect a capillary blood sample.

Target Products:

  • Roche Diagnostics - Accu-Chek Lancing Devices
 
Drug Delivery
Infusion Therapy  
Delivery Systems  
Insulin  
Pumps  
External/Random Analysis Monitoring System
External pump that delivers insulin to the patient and measure patient glucose levels as a blood sample is obtained.

Target Products:

  • Roche Diagnostics - Accu-Chek Combo
 
Implanted
Implanted pump that delivers insulin to the patient.

Target Products:

  • Roche Diagnostics - Solo Insulin Dispensing Patch
 
Percutaneous (Subcutaneous/Intramuscular/Intravenous)  
Automatic Injectors
Pen-shaped medical devices used to contain and deliver liquid medications to a specified needle depth with a press of a button.

Buyer Products:

  • Meridian Medical Technologies Auto-Injectors
 
General Surgery  
Invasive  
Surgical-Site Treatments  
Sealants  
Hemostatic  
Topical
Topical mixture used when conventional hemostasis procedures are not effective.

Buyer Products:

  • ThrombiGel/Thrombi-Pad (Thrombin/Carboxymethylcellulose)
 
Orthopedics  
Surgical  
Procedure Specific  
Bone Loss Reconstruction  
Maxillofacial
Devices used to reconstruct areas of bone loss in maxillofacial region.

Buyer Products:

  • Medtronic - Sofamor Danek INFUSE Bone Graft (rhBMP-2 Matrix)
 
Tibia
Devices used to reconstruct areas of bone loss in the tibia/lower leg.

Buyer Products:

  • Medtronic - Sofamor Danek INFUSE Bone Graft (rhBMP-2 Matrix)
 
Joint Replacement/Reconstruction  
Spine  
Spinal Implants  
Bone Growth Stimulators
Implantable devices that stimulate bone growth

Buyer Products:

  • Medtronic - Sofamor Danek INFUSE Bone Graft (rhBMP-2 Matrix)
 
Radiology  
Nuclear  
Gamma Camera  
Contrast Agents  
Radionuclides  
Adjuncts
Radioactive materials that are introduced to the body for nuclear imaging purposes.

Buyer Products:

  • Adenoscan
 
Nutritional Health  
Dietary/Naturopathic Supplements  
General Health
Products consisting of dietary/naturopathic supplements that are intended to support general health.

Buyer Products:

  • Ferrosan Consumer Health (Europe)
  • Emergen-C
  • Centrum
  • Pfizer, Inc.
 
Men`s Health
Products consisting of dietary/naturopathic supplements that are intended to support men's health.

Buyer Products:

  • Pfizer, Inc.
 
Women`s Health
Products consisting of dietary/naturopathic supplements that are intended to support women's health.

Buyer Products:

  • Caltrate
 
Outsourced Biomedical Services
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Target Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
 
Bioanalytical Services  
Nucleic Acid Sequencing
Bioanalytical services that identify the location of each nucleotide in a nucleic acid sample.

Target Products:

  • Roche Diagnostics - 454 Life Sciences Sequencing Services
 
Nucleic Acid Synthesis
Bioanalytical services that produce nucleic acids from individual nucleotides.

Target Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
 
Development/Manufacturing Services  
Contract Manufacturing Organizations (CMO)  
Biopharmaceutical OEM  
Active/Intermediate Chemicals
Intermediate and active ingredient contract manufacturing organizations that produce large quantities of small molecule compounds for use in final dosage forms.

Buyer Products:

  • Pfizer CentreSource
 
Biologics
Active Ingredient Contract Manufacturing Organizations (CMO) that manufacture antibodies, proteins, and genetic materials.

Buyer Products:

  • King Pharmaceuticals Contract Manufacturing Services
  • Pfizer CentreSource
 
Final Dosage Forms
Contract Manufacturing Organizations (CMO) that produce large quantities of drug products in final dosage forms ready to be sold to end users.

Buyer Products:

  • Pfizer CentreSource
 
Drug Discovery Services  
Lead Discovery/Validation/Optimization  
Assay Development
Bioanalytical services that are used to develop biologically based tests for use in high throughput screening (HTS).

Target Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
 
High Throughput Screening (HTS)
Bioanalytical services that allow for the biological testing of up to 10,000 compounds each day.

Target Products:

  • Roche Diagnostics - BioVeris Sector Line
  • Roche Diagnostics - BioVeris Contract Services Organization
 
Lead Biologics  
Antibodies
Biological lead compounds which have a specific amino acid sequence that only interacts with specific substances to cause an immunological response.

Target Products:

  • ARIUS FunctionFIRST Technology
 
Target Discovery/Validation  
Databases  
Genomics  
Human
Genomic databases that contain human genetic information.

Target Products:

  • Roche NimbleGen - SeqCap EZ Library
 
Services
Drug discovery services that discover and validate drug targets for the development of novel biopharmaceutical drugs.

Target Products:

  • Roche Diagnostics - BioVeris Sector Line
 
Scientific Products  
Analytical Instruments  
Automation/Processing Equipment  
Automation Equipment  
Robotic Instruments  
Workstations
Robotic instrument systems that transfer liquid and gas samples and also heat and cool samples.

Target Products:

  • Roche Diagnostics - Task Targeted Automation
 
Bioanalytical Instruments  
Bioanalytical Consumables  
Cell Biology  
Cell Culture  
Cell Lines
Cell biology consumables that is a permanently established cell culture which proliferates indefinitely given appropriate fresh medium and space.

Target Products:

  • Roche Diagnostics - BioVeris Giant Cell Tumor Conditioned Medium (GCT-CM)
 
Hybridomas
Cell culture reagents that are used to support Hybridomas for antibody production.

Target Products:

  • Roche Diagnostics - BioVeris Hybridoma Cloning Factor (HCF)
 
Media
Cell biology consumables used for the growth of cells or organs.

Target Products:

  • Roche Diagnostics - BioVeris Hybridoma Cloning Factor (HCF)
 
Reagents  
Lymphokines/Cytokines
Cell culture reagents that are used during cellular assays.

Target Products:

  • Roche Diagnostics - BioVeris Immunoassay Reagents
 
Stains/Dyes
Cell culture reagents used for the coloration of samples.

Target Products:

  • Roche Diagnostics - BioVeris BV-TAG
 
Immunology  
Kits  
Enzyme-Linked Immunoabsorbent Assay (ELISA)
Kits used for the generalized analysis of serum samples for the detection of antibodies to infectious diseases.

Target Products:

  • Roche Diagnostics - BioVeris Immunoassay Reagents
 
Reagents  
Proteins  
Antibodies
Immunology proteins that are used for the detection of specific substances, including conjugated, unconjugated, monoclonal and polyclonal antibodies.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
 
Cytokines
Immunology reagents that are used as intracellular mediators.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
 
Enzymes
Immunology reagents that are produced by a living organism to catalyze a chemical reaction.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
 
Molecular Biology  
Electrochemiluminescence (ECL)  
Reagents
Chemicals used in the preparation and analysis of samples.

Target Products:

  • Roche Diagnostics - BioVeris Protein-Protein, Receptor-Ligand And Nucleic Acid-Protein Binding Assays
  • Roche Diagnostics - BioVeris Nucleic Acid Detecion Assays
  • Roche Diagnostics - BioVerify Test Kit
 
Nucleic Acid Analysis  
Automated Nucleic Acid Purification Systems
Fully automated systems for purification of DNA/RNA from blood samples.

Target Products:

  • Roche Diagnostics - Cobas s 201 System
 
Kits  
Nucleic Acid  
Sequencing
Nucleic acid analysis kits that are used for the sequencing of genetic samples.

Target Products:

  • Roche Diagnostics - 454 Life Sciences Genetic Variation/Sequencing Kits
 
Transfection
Nucleic acid analysis kits that are used for the introduction of DNA into a recipient eukaryote cell and its subsequent integration into the recipient cells chromosomal DNA

Target Products:

  • Roche Diagnostics - FuGENE
 
Polymerase Chain Reaction (PCR)  
Amplification
Polymerase chain reaction (PCR) consumables used for the amplification of genetic samples.

Target Products:

  • Roche Diagnostics - COBAS AmpliPrep/COBAS TaqMan System
 
Detection
Polymerase chain reaction (PCR) consumables used for the detection of genetic samples.

Target Products:

  • Roche Custom Biotech MycoTOOL PCR-Test
  • Roche Diagnostics - FastStart High Fidelity PCR System
  • Roche Diagnostics - COBAS AmpliPrep/COBAS TaqMan System
 
Purification
Polymerase chain reaction (PCR) consumables used for the purification of genetic samples.

Target Products:

  • Roche Diagnostics - FastStart High Fidelity PCR System
 
Reagents  
Nucleic Acids
Nucleic acid analysis reagents that are made of nucleotides.

Target Products:

  • Roche Diagnostics - Spring BioScience FastClone PCR-Ready cDNAs
  • Roche Diagnostics - BioVeris Nucleic Acid Detecion Assays
 
Protein Analysis  
Kits  
Detection
Protein analysis kits used for the detection of amino acids.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
  • Roche Diagnostics - BioVeris Protein-Protein, Receptor-Ligand And Nucleic Acid-Protein Binding Assays
 
Expression
Kits used to perform protein expression analysis.

Target Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
 
Biomolecular  
Microarray Technology  
Consumables
Molecular biology consumables used for microarray and biochip instrumentation. Includes kits, chips, and reagents.

Target Products:

  • Roche Diagnostics - Nimblegen Sequence Capture Arrays
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
  • Roche Diagnostics - AmpliChip CYP 450
 
Microplate Readers  
Accessories
Supplementary products used to enhance the performance of a microplate reader, including detectors, incubators, dispensers, plate handlers, validation plates, and washers. Also includes consumable microplate reader kits.

Target Products:

  • Roche Diagnostics - BioVeris M-Series Kits
 
Systems  
Multiple Parameter
Microplate reader systems that used a combination of fluorescent, luminescent, and/or photoemission detectors.

Target Products:

  • Innovatis Systems - Cellavista Analyzer
  • Roche Diagnostics - Lumi-Imager
 
Single Parameter  
Electrochemiluminescence (ECL)
Microplate reader systems that use electrochemiluminescent (ECL) detectors.

Target Products:

  • Roche Diagnostics - BioVeris M-Series Analyzer
 
Sequencers  
Automated  
Nucleic Acid
Automated sequencers that employ gel electrophoresis or capillary electrophoresis to analyze nucleic acid samples.

Target Products:

  • Roche Diagnostics - 454 Life Sciences Genome Sequencer 20
  • Roche Diagnostics - 454 Life Sciences Genome Sequencer FLX System
 
Synthesizers  
Deoxyribonucleic Acid (DNA)/Oligonucleotides
Synthesizer system used for the identification and synthesis of nucleic acid samples.

Target Products:

  • MagNA Pure 96 Nucleic Acid Purification System
 
Peptides
Synthesizer systems used for the identification and synthesis of peptide samples.

Target Products:

  • Roche Diagnostics - Rapid Translation System
 
Thermal Cyclers  
Accessories
Supplementary products used to enhance the performance of a thermal cycler.

Target Products:

  • Roche Diagnostics - MagNA Pure LC
 
Systems
Thermal cycler components assembled as a single unit.

Target Products:

  • Roche Diagnostics - LightCycler Series Real-Time PCR Systems
 
Cellular  
Flow Cytometers  
Systems
Flow cytometer components assembled as a single unit.

Target Products:

  • Roche Diagnostics - xCELLigence RTCA HT System
 
Veterinary Products and Services  
Veterinary Diagnostics
The Veterinary Diagnostics Subsector includes companies that manufacture veterinary diagnostics for the detection and monitoring of veterinary diseases.

Buyer Products:

  • Pfizer Animal Health - Synbiotics Corporation
 
Veterinary Pharmaceuticals
The Veterinary Pharmaceuticals Subsector includes companies that manufacture veterinary pharmaceuticals and vaccines for the prevention and treatment of veterinary diseases.

Buyer Products:

  • Synbiotics Corporation
  • Pfizer Animal Health
  • Embrex, Inc.
  • Fort Dodge Animal Health
 
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting  
Industry-Specific IT Services  
Healthcare
IT solutions tailored and marketed for the healthcare industry.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Vantage Workflow Management Solution
 
Software  
Industry-Specific  
Healthcare/Pharma  
Business Management/Information Systems  
Patient Data Management  
Medical Image/PACS Management
Data management/PACS (Picture Archiving and Communication System) systems that are designed to store, index, access, and distribute digital medical images, such as x-rays.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso Digital Pathology Software
 
Drug Development  
Molecular Biology  
General Imaging
Software that is used to capture, analyze, store, or enhance molecular biology images that are not specific to any given imaging process.

Target Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso Digital Pathology Software
 

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Johnson & Johnson n/a 173,601.426 9.96 12.41 1.53 2.61 n/a
Merck & Co Inc n/a 116,518.823 16.80 9.96 2.42 2.49 12.01
GlaxoSmithKline PLC n/a 112,212.429 14.92 11.28 3.53 2.50 n/a
Abbott Laboratories n/a 95,838.446 18.66 12.30 2.44 2.42 n/a
Sanofi n/a 92,247.629 18.09 8.74 2.16 2.01 n/a
Amgen Inc n/a 63,900.920 17.21 11.66 4.01 3.99 19.32
Astrazeneca PLC n/a 55,862.085 6.70 6.82 1.71 1.94 90.39
Bristol Myers Squibb Co n/a 55,809.424 14.67 16.79 2.60 3.12 11.82
Eli Lilly & Co n/a 46,816.943 10.86 12.39 1.95 2.07 4.89
Gilead Sciences Inc n/a 38,526.468 14.94 14.61 4.41 4.22 n/a
Biogen IDEC Inc n/a 31,914.176 25.95 21.64 6.21 6.01 9.58
Celgene Corp n/a 31,244.689 21.68 15.88 6.26 5.82 5.14
Allergan Inc n/a 27,300.906 27.16 21.26 4.93 4.66 12.31
Vertex Pharmaceuticals Inc n/a 12,764.112 n/a 24.31 6.90 6.68 54.08
Regeneron Pharmaceuticals Inc n/a 11,016.269 n/a 117.51 19.48 10.86 21.86
Warner Chilcott PLC n/a 5,056.104 16.51 5.90 1.90 2.08 n/a
Amylin Pharmaceuticals Inc n/a 3,909.943 n/a -14.63 6.01 5.87 n/a
Onyx Pharmaceuticals Inc n/a 2,657.434 n/a -13.95 5.88 9.14 17.82
Seattle Genetics Inc n/a 2,301.496 n/a -42.29 17.59 10.75 10.45
Ariad Pharmaceuticals Inc n/a 2,118.104 n/a -12.64 83.65 186.35 8.23
Vivus Inc n/a 1,990.468 n/a -36.94 n/a 27.69 6.11
Buyer
  Johnson & Johnson n/a 173,601.426 9.96 12.41 1.53 2.61 n/a
Roche Holding AG n/a 139,114.120 24.15 10.09 2.04 2.93 n/a
Target
  Pfizer Inc n/a 176,093.984 12.76 10.21 1.76 2.93 n/a
Johnson & Johnson n/a 173,601.426 9.96 12.41 1.53 2.61 n/a

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  PDI Inc 42.70% 128.386 n/a 78.09 0.90 0.83 2.16
Marina Biotech Inc 2.00% n/a n/a n/a n/a n/a n/a
Alexandria Real Estate Equities Inc 1.30% 4,573.396 35.80 16.27 5.31 7.80 1.35
Biomed Realty Trust Inc n/a 2,412.092 85.25 14.58 4.31 5.03 0.94
Seattle Genetics Inc n/a 2,301.496 n/a -42.29 17.59 10.75 10.45
PDL Biopharma Inc n/a 863.931 5.47 4.32 1.34 2.29 n/a
Nektar Therapeutics n/a 733.425 n/a -5.19 9.39 9.32 8.53
Medidata Solutions Inc n/a 666.218 16.54 31.29 3.43 3.13 6.99
Sangamo Biosciences Inc n/a 228.217 n/a -8.49 20.09 13.91 3.07
Dyax Corp n/a 158.984 n/a -5.03 3.06 3.06 n/a
EnerNoc Inc n/a 149.075 n/a -4.07 0.53 0.58 1.31
Compugen Ltd n/a 123.460 n/a n/a n/a n/a 6.31
Codexis Inc n/a 112.024 n/a -5.42 0.90 0.89 1.45
Tekmira Pharmaceuticals Corporation n/a 24.268 n/a -3.67 1.45 1.42 4.57
Morphosys AG n/a n/a n/a n/a n/a n/a n/a
Gerresheimer AG n/a n/a n/a n/a n/a n/a n/a
Ypsomed Holding AG n/a n/a n/a n/a n/a n/a n/a
Andreae-Noris Zahn AG ANZAG n/a n/a n/a n/a n/a n/a n/a
Buyer
  Protalix BioTherapeutics Inc 100.00% 530.623 n/a 86.86 764.82 17.46 n/a
pSivida Corp 67.00% 41.485 n/a -1.66 6.52 11.65 3.14
Target
  Synageva BioPharma Corp 96.00% n/a n/a -19.72 n/a n/a n/a
PDL Biopharma Inc 86.00% 863.931 5.47 4.32 1.34 2.29 n/a
Seattle Genetics Inc 77.00% 2,301.496 n/a -42.29 17.59 10.75 10.45
Alnylam Pharmaceuticals Inc 56.00% 422.679 n/a -7.75 5.13 6.77 2.14
PDI Inc 13.80% 128.386 n/a 78.09 0.90 0.83 2.16

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Grupo Casa Saba, S.A. (ADR) n/a 225.606 0.46 n/a 0.01 n/a 0.03
Selcuk Ecza Deposu Ticaret ve Sanayi AS n/a n/a n/a n/a n/a n/a n/a
Corporativo Fragua SAB de CV n/a n/a n/a n/a n/a n/a n/a
Buyer
  McKesson Corp 13.00% 21,539.311 37.45 12.17 0.18 0.17 n/a
Cardinal Health Inc 10.00% 14,360.023 13.91 12.97 0.13 0.14 7.68
Target
  Novartis SA n/a 142,003.622 16.43 9.70 2.40 2.46 101.58
Regeneron Pharmaceuticals Inc n/a 11,016.269 n/a 117.51 19.48 10.86 21.86
Gen-Probe Inc n/a 3,886.346 54.62 30.87 5.33 6.07 9.47
Ironwood Pharmaceuticals Inc n/a 1,130.628 n/a -9.35 16.66 11.56 6.89
Genomic Health Inc n/a 933.427 114.21 n/a 4.35 4.06 7.62
PDL Biopharma Inc n/a 863.931 5.47 4.32 1.34 2.29 n/a
Abaxis Inc n/a 748.169 74.30 39.49 4.78 4.32 4.80
Nektar Therapeutics n/a 733.425 n/a -5.19 9.39 9.32 8.53
Orasure Technologies Inc n/a 488.971 n/a -47.41 5.72 5.06 10.87
Curis Inc n/a 342.159 n/a -35.92 13.69 16.24 8.86
Grupo Casa Saba, S.A. (ADR) n/a 225.606 0.46 n/a 0.01 n/a 0.03
Heska Corporation n/a 65.072 30.21 18.53 0.93 0.78 1.34
Peregrine Pharmaceuticals Inc n/a 31.271 n/a -0.93 1.97 1.82 2.42
Response Genetics Inc n/a 29.306 n/a -3.48 1.42 1.55 n/a
Helicos BioSciences Corp n/a 7.859 n/a n/a 3.03 n/a n/a
Fleury SA n/a n/a n/a n/a n/a n/a n/a
PT Tempo Scan Pacific Tbk n/a n/a n/a n/a n/a n/a n/a
PT Enseval Putera Megatrading Tbk n/a n/a n/a n/a n/a n/a n/a
Selcuk Ecza Deposu Ticaret ve Sanayi AS n/a n/a n/a n/a n/a n/a n/a
Corporativo Fragua SAB de CV n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  GlaxoSmithKline PLC n/a 112,212.429 14.92 11.28 3.53 2.50 n/a
Abbott Laboratories n/a 95,838.446 18.66 12.30 2.44 2.42 n/a
Amgen Inc n/a 63,900.920 17.21 11.66 4.01 3.99 19.32
Astrazeneca PLC n/a 55,862.085 6.70 6.82 1.71 1.94 90.39
Bristol Myers Squibb Co n/a 55,809.424 14.67 16.79 2.60 3.12 11.82
Eli Lilly & Co n/a 46,816.943 10.86 12.39 1.95 2.07 4.89
Gilead Sciences Inc n/a 38,526.468 14.94 14.61 4.41 4.22 n/a
Mylan Inc n/a 8,870.955 15.88 8.53 1.41 1.31 n/a
Seattle Genetics Inc n/a 2,301.496 n/a -42.29 17.59 10.75 10.45
Genomic Health Inc n/a 933.427 114.21 n/a 4.35 4.06 7.62
PDL Biopharma Inc n/a 863.931 5.47 4.32 1.34 2.29 n/a
Nektar Therapeutics n/a 733.425 n/a -5.19 9.39 9.32 8.53
Exelixis Inc n/a 594.572 7.41 -4.38 2.18 11.33 8.66
Clovis Oncology Inc n/a 460.194 n/a -6.31 n/a 2.97 4.04
Sangamo Biosciences Inc n/a 228.217 n/a -8.49 20.09 13.91 3.07
Grupo Casa Saba, S.A. (ADR) n/a 225.606 0.46 n/a 0.01 n/a 0.03
Compugen Ltd n/a 123.460 n/a n/a n/a n/a 6.31
Faes Farma SA n/a n/a n/a n/a n/a n/a n/a
EIS Eczacibasi Ilac Sanayi ve Ticaret A.S. n/a n/a n/a n/a n/a n/a n/a
Yiaco Medical Co. K.S.C.C n/a n/a n/a n/a n/a n/a n/a
Selcuk Ecza Deposu Ticaret ve Sanayi AS n/a n/a n/a n/a n/a n/a n/a
Buyer
  Johnson & Johnson n/a 173,601.426 9.96 12.41 1.53 2.61 n/a
GlaxoSmithKline PLC n/a 112,212.429 14.92 11.28 3.53 2.50 n/a
Target
  International Business Machines Corp IBM n/a 233,935.175 14.85 13.18 2.19 2.19 n/a
Novartis SA n/a 142,003.622 16.43 9.70 2.40 2.46 101.58

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 99,814.0 68,347.2 168,161.2
Other Revenue n/a n/a n/a
Total Revenue 99,814.0 68,347.2 168,161.2
Cost of Revenue 21,785.0 13,313.8 35,098.8
SG&A Expense 28,446.0 10,836.3 39,282.3
Depreciation & Amortization 8,400.0 11.0 8,411.0
Research & Development 12,530.0 8,955.3 21,485.3
Interest Expense 287.0 n/a 287.0
Other Operating Expense 259.0 -1,761.1 -1,502.1
Unusual Expense (Income) 7,848.0 943.1 8,791.1
Total Expenses 80,817.0 32,298.5 113,115.5
Operating Income 18,997.0 36,048.7 55,045.7
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng n/a -1,249.5 -1,249.5
Other, Net n/a 449.8 449.8
Income Before Taxes 18,997.0 13,385.1 32,382.1
Income Taxes 5,867.0 2,658.0 8,525.0
Income After Taxes 13,130.0 10,727.1 23,857.1
Minority Interest (IS) -59.0 -225.3 -284.3
Net Income - Excl. Xord. Items 13,071.0 10,501.8 23,572.8
Discontinued Operations 1,342.0 n/a 1,342.0
Net Income - Incl. Xord. Items 14,413.0 10,501.8 24,914.8
Income Avail. to Common 14,413.0 10,501.8 24,914.8
Share Items
Basic Avg. Shares Outstanding 7,537.0 848.0 8,385.0
Basic EPS - Excl. Xord. Items 1.66 12.37 2.81
Basic EPS - Incl. Xord. Items 1.83 6.80 2.97
Full Dilution Adjustment n/a -1.0 -1.0
Fully Diluted Shares Outstanding 7,598.0 849.2 8,447.2
F.D. EPS - Excl. Xord. Items 1.65 6.78 2.79
F.D. EPS - Incl. Xord. Items 1.82 6.78 2.95
Dividends Per Common Share 1.22 6.80 8.02
Balance Sheet
Assets
Cash and Equivalents 2,934.0 3,854.0 6,788.0
ST Investments 21,038.0 7,433.0 28,471.0
Accounts Receivable 14,182.0 9,799.0 23,981.0
Inventory 7,189.0 5,060.0 12,249.0
Other Current Assets 9,520.0 2,086.0 11,606.0
Current Assets 54,863.0 28,232.0 83,095.0
Accum D&A n/a n/a n/a
PPE, Net 16,192.0 16,201.0 32,393.0
Goodwill & Intangibles 98,053.0 12,969.0 111,022.0
Long Term Investments 10,632.0 384.0 11,016.0
Other Assets n/a n/a n/a
Other LT Assets 5,943.0 3,790.0 9,733.0
Total Assets 185,683.0 61,576.0 247,259.0
Liabilities
Accounts Payable 3,091.0 2,053.0 5,144.0
Payable/Accrued n/a n/a n/a
Accrued Expenses 1,752.0 7,511.5 9,263.5
ST Debt 5,526.0 n/a 5,526.0
Curr Port of LTD & Cap Lease Oblg n/a 3,394.0 3,394.0
Other (Current) Liabilities 16,725.0 10,763.0 27,488.0
Current Liab. 27,094.0 16,210.0 43,304.0
LT Debt 33,543.0 23,459.0 57,002.0
Total LT Debt 33,543.0 23,459.0 57,002.0
Minority Interest (BS) 421.0 2,387.0 2,808.0
Deferred Taxes 19,739.0 604.0 20,343.0
Other LT Liab. 21,630.0 6,821.0 28,451.0
Total Liabilities 102,427.0 49,481.0 151,908.0
Shareholders Equity
Preferred Stock 43.0 n/a 43.0
Common Stock 446.0 160.0 606.0
Additional Paid in Capital 71,786.0 n/a 71,786.0
Retained Earnings 48,124.0 17,369.0 65,493.0
Treasure Stock -33,519.0 n/a -33,519.0
Other Equity -3,622.0 -5,434.0 -9,056.0
ESOP Debt Guarantee -2.0 n/a -2.0
Total Equity 83,256.0 12,095.0 95,351.0
Total Liab. & Equity 185,683.0 61,576.0 247,259.0
Shares Outstanding 7,488.1 862.6 8,350.7
Cash Flow
Operating Cash Flow
CF Net Income 9,620.0 9,544.0 19,164.0
CF Depreciation 9,174.0 1,848.0 11,022.0
CF Amortization n/a 520.0 520.0
CF Deferred Taxes -20.0 n/a -20.0
Other Non-Cash Items 412.0 4,120.8 4,532.8
Change in Working Capital -814.0 4,910.4 4,096.4
Total Cash From Operating Activities 18,372.0 20,943.2 39,315.2
Investing Cash Flow (not calculated)
Capital Expenditures -1,664.0 -3,450.8 -5,114.8
Other Investing Cash Flows 3,590.0 5,803.7 9,393.7
Total Cash From Investing Activities 1,926.0 2,352.9 4,278.9
Financing Cash Flow (not calculated)
Dividends Paid -6,293.0 -12,710.8 -19,003.8
Purchase Or Sale of Stock -9,059.0 n/a -9,059.0
Purchase and Retirement of Debt -2,358.0 -2,136.1 -4,494.1
Other Financing Cash Flow n/a -2,310.6 -2,310.6
Total Cash From Financing Activities -17,710.0 -20,903.5 -38,613.5
Exchange Rate Effects -27.0 -123.7 -150.7
Net Change in Cash 2,561.0 2,269.0 4,830.0
Cash Taxes Paid 3,523.0 3,924.3 7,447.3
Cash Interest Paid 1,906.0 3,084.9 4,990.9