Summary

Other Scenarios:

Buyer: GlaxoSmithKline plc (ADR) (GSK) Last Price: 57.71 Market Cap.: 165.20B
Target: Roche Holding Ltd. (ADR) (RHHBY) Last Price: 92.90 Market Cap.: 160.26B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
*Healthcare 879
Biopharmaceuticals 337
Medical Devices 247
Nutritional Health   26
Outsourced Services   65
Scientific Products   39

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business
Buyer (Total: 282)
  • 256066
  • Contac 12 Hour Allergy (Clemastine Fumarate)
  • Contac 12 Hour/Contac Maximum Strength 12 Hour Caplets (Chlorpheniramine Maleate/Phenylpropanolamine Hydrochloride)
  • Contac Allergy/Sinus Night Capsules (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
Target (Total: 235)
  • Xolair (Omalizumab)
  • Cardene (Nicardipine Hydrochloride)
  • Dilatrend (Carvedilol)
  • Demadex (Torsemide)
Buyer
  • T.R.U.E. Test
  • ID Biomedical Velogene Genomic Identification Assay for Vancomycin-Resistant Enterococci (VRE)
  • ID Biomedical Velogene Genomic Identification Assay for MRSA
  • Diskus/Accuhaler
Target
  • Roche Diagnostics AVL Compact 1-3
  • Roche Diagnostics AVL 988 Series
  • Roche Diagnostics OMNI Series
  • Roche Diagnostics AVL 9180 Series

Business Relationship Summary:

Top Key Suppliers

Top Key Customers
Buyer (Total: 56)
  • Encysive Pharmaceuticals, Inc. (ENCY)
  • Cytokinetics, Inc. (CYTK)
  • Exelixis, Inc. (EXEL)
  • DRAXIS Health Inc. (USA) (DRAX)
Target (Total: 41)
  • Aspreva Pharmaceuticals Corporation (ASPV)
  • Pharmasset, Inc. (VRUS)
  • Emisphere Technologies, Inc. (EMIS)
  • deCODE genetics, Inc. (DCGN)
Buyer (Total: 21)
  • Wal-Mart Stores, Inc. (WMT)
  • CVS Caremark Corporation (CVS)
  • Target Corporation (TGT)
  • Walgreen Company (WAG)
Target (Total: 9)
  • Applied Biosystem Inc. (ABI)
  • Gen-Probe Incorporated (GPRO)
  • IDEXX Laboratories, Inc. (IDXX)
  • Grupo Casa Saba, S.A. (ADR) (SAB)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 101,802 74,372
Revenue Per Employee 434,993.6 485,040.7
Total Revenue 11,044.4 18,416.6
Total Expenses 6,766.5 13,499.6
Other Revenue 0.0 0.0
Cost of Revenue 2,437.2 4,715.4
SG&A Expense 3,304.2 5,907.1
Research & Development 1,433.9 2,926.1
Other Operating Expense -408.8 -613.3
Operating Income 4,277.9 4,917.0
Unusual Income 0.0 0.0
LT Debt to Capital 32.51 13.58
Fwd P/E 14.52 21.03
Fwd P/Rev 3.54 4.01
Book Value 19,622.0 32,733.6
Curr Portion of LTD/Cap Lease 0.0 1,696.3

Individual Company Summary

Focused

Buyer

Focused (): *Healthcare > Biopharmaceuticals

Target

Focused (): *Healthcare > Biopharmaceuticals

Business Description

Buyer

GlaxoSmithKline plc (GSK) is a global healthcare group, which is engaged in the creation and discovery, development, manufacture and marketing of pharmaceutical products, including vaccines, over-the-counter (OTC) medicines and health-related consumer products. The Company operates in two segments: Pharmaceuticals (prescription pharmaceuticals and vaccines), and Consumer Healthcare (over-the-counter medicines, oral care and nutritional healthcare). The major markets for the Company's products are the United States, France, Japan, the United Kingdom, Italy, Germany and Spain. During the year ended December 31, 2006, 19 new projects entered Phase II clinical trials for the first time. In February 2007, the Company announced that the United States Food and Drug Administration (FDA) approved the weight-loss product orlistat 60 milligrams capsules for OTC use in the United States. On December 19, 2006, the Company acquired CNS, Inc. In May 2006, GSK purchased Pliva Research Institute Ltd.

Target

Roche Holding Ltd. is a pharmaceuticals and a diagnostics company. The Company?s products and services cover every stage of the healthcare process, from identifying disease susceptibilities and testing for disease in at-risk populations to prevention, diagnosis, therapy and treatment monitoring. As of December 31, 2006, Roche had a 55.8% interest in Genentech, Inc. As of December 31, 2006, the Company had a 50.6% interest in Chugai Pharmaceutical Co., Ltd. Roche operates in two divisions: Pharmaceuticals and Diagnostics. Within the Pharmaceuticals Division there are three sub-divisions: Roche Pharmaceuticals, Genentech and Chugai. The Company?s Diagnostics Division offers a range of products and services in various fields of medical testing. Effective December 9, 2006, Genentech sold its wholly owned subsidiary Genentech Espana, including the manufacturing facility in Porrino, Spain, to Lonza Group Ltd. In April 2007, the Company acquired Therapeutic Human Polyclonals, Inc.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 77.79 74.75
Operating Margin % 33.91 27.9
Quick Ratio 1.11 2.62
Current Ratio 1.46 3.22
Coverage Ratio -0 0.04
Total Assets 52,093.5 61,754.4
Return on Equity % 55.37 23.2
Return on Assets % 20.86 12.3
Cash+ ST Inv. Per Share 2.09 11.69
Total Debt 11,832.4 6,840.7
Total Debt to Equity % 60.3 20.9
Total Debt to Tangible Equity % 113.32 29.38
Debt to Asset % 22.71 11.08

Product Summary

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes therapeutics that treat female genital disorders, pregnancy, and childbirth.
  
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
  
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes herapeutics that treat and manage weight disorders.
Wound Management
The Wound Management Subsector includes therapeutics that treat cuts, abrasions, and burns from trauma or diseases.
  
Medical Devices
Clinical Diagnostics
The Clinical Diagnostics Subsector includes medical devices that analyze human body specimens within a medical setting. These devices, including equipment, biological and chemical reagents are primarily used for the diagnosis of diseases.
Drug Delivery
The Drug Delivery Subsector includes medical devices that facilitate the delivery of medications through different anatomical entryways, including blood vessels, skin, the mouth, and the lungs. Common devices in this sector include vascular access catheters, needles, implants, and inhalers.
  
Respiratory
The Respiratory Subsector includes medical devices that diagnose and treat respiratory diseases.
  
Nutritional Health  
Dietary/Naturopathic Supplements
The Dietary/Naturopathic Subsector includes nutritional biochemicals and nutrients derived from natural sources that are intended to support health.
  
Outsourced Services  
Development/Manufacturing Services
The Development/Manufacturing Services Subsector includes companies that provide research, development, manufacturing, sales and marketing to biopharmaceutical and medical device companies.
  
Scientific Products  
Analytical Instruments
The Analytical Instruments Subsector includes scientific products that determine the quantitative and qualitative nature of biochemical samples.
  
Bioanalytical Instruments
The Bioanalytical Instruments Subsector includes scientific products, devices and apparatuses that determine the quantitative and qualitative nature of a biological samples.
  
Consumables
The Consumables Subsector includes chemicals, reagents, standards, media, and disposable labware that are normally depleted or worn out by continuous use.
  
General Laboratory Equipment
The General Laboratory Equipment Subsector includes products that are used during routine laboratory procedures, such as sample preparation, processing, storage, cleaning, and purification.
  

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for treatment of allergic reactions in early stages of clinical research where human subject is involved.

Buyer Products:

  • 256066

Target Products:

  • Xolair (Omalizumab)
Upper Respiratory
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Contac 12 Hour Allergy (Clemastine Fumarate)
  
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and relieve or prevent coughs.

Buyer Products:

  • Contac 12 Hour/Contac Maximum Strength 12 Hour Caplets (Chlorpheniramine Maleate/Phenylpropanolamine Hydrochloride)
  
Antihistamines/Decongestants/Analgesics/Antipyretics
Therapeutics that treat allergic reactions by suppressing inflammation, reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Allergy/Sinus Night Capsules (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
  • Contac Day And Night Allegry/Sinus Relief (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
  
Antihistamines/Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat allergic reactions by suppressing inflammation, reducing mucous build up, relieving or preventing coughs, relieving pain, and reducing fever.

Buyer Products:

  • Contac Severe Cold & Flu Hot Medicine (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Severe Cold Formula Night Strength (Doxylamine Succinate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen/Alcohol)
  • Contac Severe Cold Formula Capsules (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  
Monoclonal Antibodies
Therapeutics that treat allergic reactions by specifically binding and inhibiting inflammatory substances.

Target Products:

  • Xolair (Omalizumab)
  
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation using a steroidal compound.

Buyer Products:

  • Beconase AQ (Beclomethasone Dipropionate, Monohydrate)
  • Flonase (Fluticasone Propionate Nasal Spray)
  • Veramyst (Intranasal Fluticasone Furoate)/Formely Allermist
  
Cardiovascular System
Heart Disorders
Acute Coronary Syndrome (ACS)  
Anticoagulating Agents  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
  
Angina  
Calcium Channel Blocking Agents
Therapeutics that treat chest pains by preventing the entry of calcium into heart muscle cells.

Target Products:

  • Cardene (Nicardipine Hydrochloride)
  
Arrhythmia  
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium and potassium into heart muscle cells.

Buyer Products:

  • Lanoxin (Digoxin)
  
Heart Failure (HF)
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat the ineffective pumping of the heart by blocking beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Coreg CR (Carvedilol Controlled Release)
  • Coreg (Carvedilol)

Target Products:

  • Dilatrend (Carvedilol)
Complications
Edema
Loop Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Demadex (Torsemide)
  • Bumex (Bumetanide)
  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Dyazide (Triamterene/Hydrochlorothiazide)
  
Recombinant B-Type Natriuretic Peptides (BNP)
Therapeutics that treat the ineffective pumping of the heart by increasing the excretion of sodium and water in urine.

Buyer Products:

  • Natrecor (Nesiritide Citrate)
  
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat the ineffective pumping of the heart by preventing the entry of sodium or potassium into heart muscle cells.

Buyer Products:

  • Lanoxin (Digoxin)
  
Myocardial Infarction (MI)
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Coreg (Carvedilol)
  • Coreg CR (Carvedilol Controlled Release)

Target Products:

  • Dilatrend (Carvedilol)
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 813893 (Factor Xa Inhibitor)
  • 737004 (Endothelin A Antagonist)
  • 856553 (p38 Kinase Inhibitor)
  • Rilapladib
  • Odiparcil (Indirect Thrombin Inhibitor)
  • 681323 (p38 Kinase Inhibitor)
  • Darapladib

Target Products:

  • TF Fab (Monoclonal Antibody Fragment)
  • R639/SPP301 (Endothelin Receptor A Antagonist)
  • BO-653 (Antioxidant)
  • AXV034343 (Endothelin A Receptor Antagonist)
Vascular Disorders
Deep Vein Thrombosis (DVT)
Anticoagulating Agents (Anticoagulants)
Platelet Aggregation Inhibitors  
Adenosine Diphosphate (ADP) Inhibitors
Therapeutics that treat/prevent thrombosis by selectively inhibiting the binding of adenosine diphosphate (ADP) to its platelet receptor, thereby inhibiting platelet aggregation.

Target Products:

  • Ticlid (Ticlopidine Hydrochloride)
  
Thrombin Inhibitors
Therapeutics that prevent or treat clots in blood vessels by preventing blood clots from forming.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
  
Hypertension
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Coreg CR (Carvedilol Controlled Release)
  • Coreg (Carvedilol)
  
Calcium Channel Blocking Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Cardene (Nicardipine Hydrochloride)
  • Cardene SR (Nicardipine Hydrochloride)
  
Loop Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Demadex (Torsemide)
  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Dyazide (Triamterene/Hydrochlorothiazide)
  
Primary Pulmonary Hypertension  
Prostacyclins
Therapeutics that relieve pulmonary hypertension by causing vasodilation of the pulmonary blood vessels.

Buyer Products:

  • Flolan (Epoprostenol Sodium)
  
Stroke  
Anticoagulating Agents (Anticoagulants)  
Platelet Aggregation Inhibitors  
Adenosine Diphosphate (ADP) Inhibitors
Therapeutics that prevent or treat damage to nerve cells of the brain by preventing platelets from clumping together.

Target Products:

  • Ticlid (Ticlopidine Hydrochloride)
  
Thromboembolism  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
  
Dermatology
Acne  
Vulgaris  
Retinoids/Vitamin A Analogs
Therapeutics that treat acne by helping in cell differentiation as well as prevent cell proliferation.

Target Products:

  • Roaccutane/Accutane (Isotretinoin)
  
Lesion/Scaling Disorders
Dermatitis  
Atopic (Eczema)  
Immunomodulators
Therapeutics that treat atopic dermatitis by inhibiting T-lymphocyte activation.

Buyer Products:

  • Protopic (Tacrolimus)
  
Seborrheic (Dandruff)  
Coal Tar
A coal byproducts used in the treatment of various skin disorders.

Buyer Products:

  • Tegrin Dandruff Shampoo (Coal Tar)
  
Diaper Rash  
Zinc Oxide
Therapeutics that treat diaper rash by forming a protective barrier against the skin.

Buyer Products:

  • Balmex (Zinc Oxide)
  
Psoriasis
Monoclonal Antibodies
Therapeutics that treat psoriasis by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Target Products:

  • Raptiva (Efalizumab)
  
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skin disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 786034 (VEGF 2 Tyrosine Kinase Inhibitor)
  • 842470 (PDE-4 Inhibitor)

Target Products:

  • BAL4079 (9-Cis Retinoic Acid)
  • BAL2299 (Nuclear Receptor Modulator)
  • BCX-4208 (Second-Generation PNP Inhibitor)
Digestive System
Gastrointestinal Tract Disorders
Gastroduodenal Disorders  
Peptic Ulcers  
Duodenal  
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Zantac (Ranitidine Hydrochloride)
  • Tagamet HB 200 (Cimetidine Hydrochloride)
  
Gastric  
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Zantac (Ranitidine Hydrochloride)
  • Tagamet HB 200 (Cimetidine Hydrochloride)
  
Zollinger-Ellison Syndrome  
H2 Receptor Antagonists
Therapeutics that treat ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Zantac (Ranitidine Hydrochloride)
  
Gastroesophageal Disorders
Abdominal Gas  
Gas Bubble Surface Tension Reducing Agents
Therapeutics that treat abdominal gas by reducing the surface tension of gas bubbles in the bowels.

Buyer Products:

  • Phazyme (Simethicone)
  
Acid Indigestion/Heartburn  
Acid Neutralizing Agents
Therapeutics that treat heartburn by neutralizing stomach acid.

Buyer Products:

  • Gaviscon Regular Strength (Aluminum Hydroxide/Magnesium Trisilicate)
  • Gaviscon Extra Strength (Aluminum Hydroxide/Magnesium Carbonate)
  • TUMS (Calcium Carbonate)
  
H2 Receptor Antagonists
Therapeutics that treat indigestion by blocking the action of histamine at the H2 receptors.

Buyer Products:

  • Tagamet HB 200 (Cimetidine Hydrochloride)
  • Tagamet HB 200 (Cimetidine)
  
Erosive Esophagitis  
H2 Receptor Antagonists
Therapeutics that treat Erosive Esophagitis by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Zantac (Ranitidine Hydrochloride)
  
Gastroesophageal Reflux Disease (GERD)  
H2 Receptor Antagonists
Therapeutics that treat Gastroesophageal Reflux Disease by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Tagamet HB 200 (Cimetidine Hydrochloride)
  • Zantac EFFERdose (Ranitidine Hydrochloride Effervescent)
  • Zantac (Ranitidine Hydrochloride)
  
Nausea/Vomiting
Dopamine Receptor Blocking Agents
Therapeutics that treat or prevent nausea and vomiting by blocking the action of dopamine.

Buyer Products:

  • Thorazine (Chlorpromazine)
  • Compazine (Prochlorperazine)
  
Neurokinin-1 (NK-1) Receptor Antagonists
Therapeutics that prevent or treat nausea and vomiting by inhibiting the neurotransmitter NK-1 (Substance P) from binding to its receptors.

Buyer Products:

  • Casopitant (NK-1 Receptor Antagonist)
  
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Buyer Products:

  • Zofran/Zofran ODT (Ondansetron Hydrochloride)

Target Products:

  • Kytril (Granisetron Hydrochloride)
Intestinal Disorders  
Constipation  
Chronic  
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Buyer Products:

  • FiberChoice (Natural Fiber)
  • Citrucel (Methylcellulose)
  
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Entereg (Alvimopan)
  
Irregular Bowel Movements  
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Buyer Products:

  • FiberChoice (Natural Fiber)
  
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Entereg (Alvimopan)
  
Liver Disorders
Cirrhosis  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that prevent edema by excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Bumex (Bumetanide)
  • Demadex (Torsemide)
  
Hepatitis
Hepatitis B
Chronic
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  
Reverse Transcriptase Inhibitors (Nucleoside Analogs)
Therapeutics that treat hepatitis by inhibiting the action of reverse transcriptase, an enzyme necessary for DNA synthesis using an RNA template.

Buyer Products:

  • Zeffix (Lamivudine)
  • Epivir-HBV/Zeffix (Lamivudine)
  
Hepatitis C
Chronic
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Wellferon (Alpha Interferon N1)

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  • Roferon-A (Interferon Alfa-2a, Recombinant)
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections by preventing viral replication, stimulating the immune system to also fight the virus, and inhibits replication of viral DNA by incorporating themselves into growing viral DNA stands.

Target Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Vestipitant/Paroxetine
  • Traficet-EN
  • PowderJect DNA Vaccine
  • 683699 (VLA4 Antagonist)
  • Mepolizumab
  • Casopitant (NK-1 Receptor Antagonist)
  • 270384 (Endothelial Cell Adhesion Inhibitor)
  • 876008 (CRF1 Antagonist Back-Up Compound)
  • Vestipitant
  • Entereg (Alvimopan)

Target Products:

  • R1068 (GPCR Modulator)
  • R1270 (Levovirin)
  • R1124 (GPCR Modulator)
  • GM -611 (Motilin Agonist)
  • R440 (Cell Cycle Inhibitor)
  • R1518 (Levovirin)
  • R1479 (Polymerase Inhibitor)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1626 (Polymerase Inhibitor)
  • ITMN-191 (Protease Inhibitor)
  • R1541 (Integrin Antagonist)
  • R7025/MAXY-Alpha (Interferon Alpha)
  
Endocrinology/Metabolism
Diabetes
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes
Biguanides/Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Therapeutics that control high blood sugar by stimulating the release of insulin as well as sensitizing organs to insulin.

Buyer Products:

  • Avandamet (Rosiglitazone Maleate/Metformin)
  
Insulin Stimulating Agents (Sulfonylureas)/PPAR Agonists
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin and sensitizing organs to insulin.

Buyer Products:

  • Avandaryl (Rosiglitazone Maleate/Glimepiride)
  • Avandamet XR (Rosiglitazone Maleate/Metformin)
  
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Products that sensitizes organs to insulin.

Buyer Products:

  • Avandia (Rosiglitazone Maleate)

Target Products:

  • R483 (Insulin Sensitizer)
Intermediary Metabolism Disorders
Gout  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation preventing cyclooxygenase activity.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Porphyrias  
Acute Intermittent  
Dopamine Receptor Blocking Agents
Therapeutics that treat porphyrias by blocking the receptor that binds the neurotransmitter, dopamine.

Buyer Products:

  • Thorazine (Chlorpromazine)
  
Parathyroid Gland Disorders  
Hyperparathyroidism (HPT)  
Vitamin D Analogs
Therapeutics that act similar to Vitamin D.

Target Products:

  • Rocaltrol (Calcitriol)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Denagliptin
  • Solabegron
  • 232802 (Selective Estrogen Receptor Modulator)
  • 256073
  • 501516
  • 677954 (Dual PPAR Agonist)
  • 625019
  • 189075 (Sodium Dependent Glucose Transport (SGLT-2) Inhibitor)
  • 590735
  • Albugon/GSK716155 (Albumin-Glucagon)

Target Products:

  • BIM 51077 (GLP-1 Analogue)
  • R1438 (Enzyme Inhibitor)
  • R1440 (Enzyme Modulator)
  • R1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
  • R1439 (Nuclear Receptor Modulator)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Peroxisome Proliferator Activated Receptor (PPAR) Modulators

Target Products:

  • R1593 (Nuclear Receptor Modulator)
  • R1498 (Nuclear Receptor Modulator)
  • R1499 (Enzyme Inhibitor)
  • Glucokinase Enzyme
Hematology
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 256073
  • 590735
  • 501516
  • GSK626616 (DYRK3 Antagonist)
  • 559448 (Thrombopoietin Analog)

Target Products:

  • R1516
  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
  • R1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
Red Blood Cell (RBC) Disorders  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues by stimulating red blood cell production.

Target Products:

  • NeoRecormon (Epoetin Beta)
  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1593 (Nuclear Receptor Modulator)
  
Serum Factor Disorders  
Hypocalcemia  
Vitamin D Analogs
Therapeutics that treat hypocalcemia by increasing serum levels of calcium, as well as helping the bone calcification process.

Target Products:

  • Rocaltrol (Calcitriol)
  
Thrombocyte (Platelet) Disorders  
Thrombocytopenia  
Thrombopoietin Agonists
Therapeutics that treat thrombocytopenia by stimulating thrombopoietin, which promotes the production of platelets.

Buyer Products:

  • Promacta (Eltrombopag)
  
Immunology
Autoimmune Disorders
Arthritis
Rheumatoid Arthritis (RA)
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Relafen (Nabumetone)
  
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Rituxan (Rituximab)
  • Actemra (Tocilizumab)
  
Idiopathic Thrombocytopenia Purpura (ITP)  
Thrombopoietin Agonists
Therapeutics that treat thrombocytopenia by stimulating thrombopoietin, which promotes the production of platelets.

Buyer Products:

  • Promacta (Eltrombopag)
  
Lupus Erythematosus  
Systemic (SLE)  
Monoclonal Antibodies
Therapeutics that treat systemic lupus by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Buyer Products:

  • LymphoStat-B (Belimumab)
  
Psoriasis
Monoclonal Antibodies
Therapeutics that treat psoriasis by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Target Products:

  • Raptiva (Efalizumab)
  
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)  
Immune Deficiency Disorders
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • Aplaviroc (Cellular Chemokine Receptor (CCR5) Antagonist)
  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Target Products:

  • Fuzeon (Enfuvirtide)
  
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • Combivir (Lamivudine/Zidovudine)
  • Epivir (Lamivudine)
  • Epzicom (Abacavir/Lamivudine)
  • Ziagen (Abacavir Sulfate)
  • Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • Retrovir (Zidovudine)

Target Products:

  • Hivid (Zalcitabine)
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Agenerase (Amprenavir)
  • Lexiva (Fosamprenavir Calcium)

Target Products:

  • Fortovase (Saquinivir)
  • Invirase (Saquinavir Mesylate)
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 786034 (VEGF 2 Tyrosine Kinase Inhibitor)
  • Traficet-EN
  • Aplaviroc (Cellular Chemokine Receptor (CCR5) Antagonist)
  • Brecanavir/VX-385
  • LymphoStat-B (Belimumab)
  • 681323 (p38 Kinase Inhibitor)
  • 270384 (Endothelial Cell Adhesion Inhibitor)
  • 683699 (VLA4 Antagonist)
  • Rosiglitazone XR
  • Human Immunodeficiency Virus (HIV) Vaccine
  • 856553 (p38 Kinase Inhibitor)

Target Products:

  • Fortovase (Saquinivir)
  • R1295 (Integrin Antagonist)
  • Raptiva (Efalizumab)
  • BR3-FC (Soluble BAFF Antagonist) Protein Therapeutic
  • R1594 (Anti-CD20 Molecule )
  • R944 (Protease Inhibitor)
  • BAL2299 (Nuclear Receptor Modulator)
  • R1487 (Kinase Inhibitor)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • R724/T-1249 (Fusion Inhibitor)
  • Humanized Anti-CD20 (Ocrelizumab)
  • R1599
  • R1503 (Kinase Inhibitor)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1541 (Integrin Antagonist)
  • R1495 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • CLIP (Class II Associated Invariant Chain Peptide)
  • R1628
  • BCX-4208 (Second-Generation PNP Inhibitor)
  
Infectious Diseases
Bacterial
Antibacterial Agents
Broad Spectrum
Antibiotics
Cephalosporin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Zinacef (Cefuroxime)
  • Ancef (Cefazolin Sodium)
  • Fortaz (Ceftazidime)
  • Ceftin (Cefuroxime Axetil)
  • Ceptaz (Ceftazidime)
  • Monocid (Cefonicid Sodium)

Target Products:

  • Rocephin (Ceftriaxone Sodium)
Penicillin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication.

Buyer Products:

  • Ticar (Ticarcillin Disodium)
  • Amoxil (Amoxicillin)
  • Amoxil Pediatric (Amoxicillin)
  
Penicillin Derivatives/Beta-Lactamase Inhibitors
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication and increasing susceptibility to penicillin derived compounds.

Buyer Products:

  • Augmentin XR (Amoxicillin/Clavulanate Potassium)
  • Timentin (Ticarcillin Disodium/Clavulanate Potassium)
  • Augmentin (Amoxicillin/Clavulanate Potassium)
  
Pleuromutilins
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis through binding onto ribosome.

Buyer Products:

  • Altabax (Retapamulin)
  
Pseudominic Acids
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis and RNA synthesis.

Buyer Products:

  • Bactroban (Mupirocin Calcium)
  • Bactroban Ointment (Mupirocin)
  • Bactroban Nasal (Mupirocin Calcium)
  
Sulfonamides
Therapeutics that treat a wide variety of bacterial infections by inhibiting folic acid synthesis.

Target Products:

  • Gantrisin (Sulfisoxazole)
  
Narrow Spectrum
Digestive System  
Shigellosis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat an infection of the intestines caused by Shigella by inhibiting folic acid synthesis.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Musculoskeletal System  
Bone/Joint Infections  
Cephalosporin Derivatives
Therapeutics that treat bacterial infections manifested in the bones or joints by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)
  • Zinacef (Cefuroxime)
  
Neurology  
Meningitis  
Cephalosporin Derivatives
Therapeutics that treat inflammation of the lining of the brain and spinal cord by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Zinacef (Cefuroxime)
  
Otolaryngology (Ear/Nose/Throat)
Otitis Media
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the middle ear inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Penicillin Derivatives/Beta-Lactamase Inhibitors
Therapeutics that treat infection and inflammation of the middle ear space and ear drum by inhibiting bacterial cell wall synthesis during active multiplication and increasing susceptibility to penicillin derived compounds.

Buyer Products:

  • Augmentin ES-600 (Amoxicillin/Clavulanate Potasium)
  
Respiratory System
Bronchitis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the bronchi in the lungs by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Pharyngitis  
Cephalosporin Derivatives
Therapeutics that treat inflammation of the cone shaped cavity at the back of the mouth caused by bacterial infection by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)
  
Respiratory Tract Infections  
Cephalosporin Derivatives
Therapeutics that treat infections of the air passage caused by a wide variety of bacteria.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)
  • Zinacef (Cefuroxime)
  
Tonsilitis  
Cephalosporin Derivatives
Therapeutics that treat inflammation of the lymphoid tissue on either side of the throat caused by bacterial infection by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)
  
Urology  
Urinary Tract Infections (UTI)  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections of the urinary tract by inhibiting dihydrofolate reductase resulting in decreased bacterial nucleic acid/protein production.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Vaccines  
Bacterial  
Combination  
Diphtheria/Tetanus/Acellular Pertussis (DTaP)
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause diphtheria, tetanus, and acellular pertussis.

Buyer Products:

  • Infanrix (Diphteria And Tetanus Toxoids And Acellular Pertussis Vaccine Aborbed)
  • Boostrix (Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccine, Adsorbed (Tdap))
  
Single Target  
Meningitis
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause meningitis.

Buyer Products:

  • Mencevax
  • Neissaria Meningitidis Vaccine
  
Streptococcus pneumoniae
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause pneumococcal bacteria.

Buyer Products:

  • Streptorix
  
Typhoid Fever
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause typhoid fever.

Buyer Products:

  • Typherix (Purified Polysaccharide Antigen)
  
Bacterial/Viral
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to a bacterial or viral pathogen.

Buyer Products:

  • Infanrix HeXa-HepB-IPV/Hib
  • Pediarix
  
Helminthic  
Hydatid Disease  
Antimicrotubule Agents
Therapeutics that treat parasitic infections characterized by formation of cysts in a several organs.

Buyer Products:

  • Albenza (Albendazole)
  
Neurocysticercosis  
Antimicrotubule Agents
Therapeutics that treat parasitic infections caused by a tapeworm in the brain.

Buyer Products:

  • Albenza (Albendazole)
  
Mycological (Fungal)
Antifungal Agents
Narrow Spectrum
Respiratory System
Pneumocystis Carinii Pneumonia (PCP)
Dihydrofolate Reductase Inhibitors/Dihydropteroate Synthetase Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by interfering with folic acid synthesis and growth of organism.

Target Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Protozoan Metabolism Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by preventing metabolism and growth in organism.

Buyer Products:

  • Mepron/Wellvone (Atovaquone)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Buyer Products:

  • 825780 (DNA Antiviral Vaccine)
  • 565154 (Oral Pluromutilin)
  • Varicella Zoster Vaccine
  • Farglitazar
  • 742510
  • Tuberculosis Vaccine
  • Valtrex XR
  • Staphylococcal Antibodies Vaccine
  • Dengue Fever Vaccine
  • Boostrix-IPV
  • Brecanavir/VX-385
  • Aplaviroc (Cellular Chemokine Receptor (CCR5) Antagonist)
  • Influenza Vaccine (Flu Vaccine)
  • Hib-MenCY-TT
  • Streptococcus pneumoniae Vaccine
  • FluINsure
  • Respiratory Syncytial Virus (RSV) Vaccine
  • PowderJect DNA Vaccine
  • Mosquirix (Malaria Vaccine)
  • Human Immunodeficiency Virus (HIV) Vaccine
  • 270773 (Phospholipid Anti-Endotoxin)
  • Epstein Barr Virus (EBV) Vaccine
  • Bactroban (Mupirocin Calcium)

Target Products:

  • R1479 (Polymerase Inhibitor)
  • R1270 (Levovirin)
  • R724/T-1249 (Fusion Inhibitor)
  • R944 (Protease Inhibitor)
  • CS-023 (Prenteral Crbapenem)
  • R1461 (Fusion Protein)
  • R1558
  • ITMN-191 (Protease Inhibitor)
  • R7025/MAXY-Alpha (Interferon Alpha)
  • Fortovase (Saquinivir)
  • BAL8557 (Antifungal Agent)
  • BAL5788 (Antibiotic)
  • R1518 (Levovirin)
Protozoal
Antiprotozoal Agents
Narrow Spectrum
Malaria
Aminoquinolines
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by inhibiting parasite growth.

Buyer Products:

  • Etaquine

Target Products:

  • Lariam (Mefloquine Hydrochloride)
Diaminopyrimidines/Sulfonamides
Therapeutics that treat infections due to parasites by inhibiting folic acid synthesis and also blocking the action of the dihydrofolate enzyme.

Target Products:

  • Fansidar (Sulfadoxine/Pyrimethamine)
  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by blocking the action of the dihydrofolate enzyme.

Buyer Products:

  • Malarone (Atovaquone/Proguanil)
  • Daraprim (Pyrimethamine)
  
Toxoplasmosis (Toxo)  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat infections caused by Toxoplasma gondii and characterized by lesions in the heart, brain, and eye by preventing folic acid synthesis.

Buyer Products:

  • Daraprim (Pyrimethamine)
  
Visceral Leishmaniasis  
Aminoquinolines
Therapeutics that treat infections characterized by Leishmania in macrophages by interfering with the cell cycle.

Buyer Products:

  • Sitamaquine
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in very early stages of research where no human subject is involved.

Buyer Products:

  • Relenza (Zanamivir)

Target Products:

  • BAL8349 (Antifungal Agent)
  • R1495 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • Tamiflu (Oseltamivir)
  • R1626 (Polymerase Inhibitor)
Viral
DNA Viruses
Hepadnavirus
Hepatitis B
Chronic
Interferons
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months with natural proteins that have antiviral activity.

Target Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  
Reverse Transcriptase Inhibitors (Nucleoside Analogs)
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months by blocking enzyme essential for viral DNA synthesis.

Buyer Products:

  • Zeffix (Lamivudine)
  • Epivir-HBV/Zeffix (Lamivudine)
  
Herpesvirus
Cytomegalovirus (CMV)  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  
Herpes Labialis (Cold Sores)  
Purine Nucleoside Analogs
Therapeutics that treat viral infections by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)
  
Viral Fusion Inhibitors
Therapeutics that treat cold sores by inhibiting fusion of viral material into human cell plasma membranes.

Buyer Products:

  • Abreva (Docosanol)
  
Herpes Simplex Type 1  
Purine Nucleoside Analogs
Therapeutics that treat viral infections characterized by recurrent cold sores and fever blisters by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex/Zelitrex (Valacyclovir Hydrochloride)
  • Valtrex (Valacyclovir Hydrochloride)
  • Zovirax (Acyclovir)
  
Herpes Simplex Type 2  
Purine Nucleoside Analogs
Therapeutics that treat viral infections characterized by recurring outbreaks of painful genital lesions by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Zovirax (Acyclovir)
  • Valtrex/Zelitrex (Valacyclovir Hydrochloride)
  • Valtrex (Valacyclovir Hydrochloride)
  
Varicella Zoster  
Herpes Zoster (Shingles)  
Purine Nucleoside Analogs
Therapeutics that treat viral infections that cause shingles in adults by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)
  • Zovirax (Acyclovir)
  
Varicella (Chickenpox)  
Purine Nucleoside Analogs
Therapeutics that treat viral infections that cause chicken pox in children by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)
  • Zovirax (Acyclovir)
  
RNA Viruses
Flavivirus
Hepatitis C
Chronic
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Wellferon (Alpha Interferon N1)

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  • Pegasys (Pegylated Interferon Alfa-2a)
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections characterized by long term inflammation of the liver by enhancing the immune system and by inhibiting replication of viral DNA.

Target Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
  
Orthomyxovirus
Influenza A
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza A virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Relenza (Zanamivir)

Target Products:

  • Tamiflu (Oseltamivir)
Influenza B
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza B virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Relenza (Zanamivir)

Target Products:

  • Tamiflu (Oseltamivir)
Retrovirus
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • Aplaviroc (Cellular Chemokine Receptor (CCR5) Antagonist)
  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Target Products:

  • Fuzeon (Enfuvirtide)
  
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • Epivir (Lamivudine)
  • Ziagen (Abacavir Sulfate)
  • Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • Retrovir (Zidovudine)
  • Combivir (Lamivudine/Zidovudine)
  • Epzicom (Abacavir/Lamivudine)

Target Products:

  • Hivid (Zalcitabine)
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Agenerase (Amprenavir)
  • Lexiva (Fosamprenavir Calcium)

Target Products:

  • Invirase (Saquinavir Mesylate)
  • Fortovase (Saquinivir)
Vaccines  
Bacterial/Viral
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to a bacterial and viral pathogens.

Buyer Products:

  • Infanrix HeXa-HepB-IPV/Hib
  • Pediarix
  
Viral  
Combination  
Hepatitis A/Hepatitis B
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to Hepatitis A and Hepatitis B viruses.

Buyer Products:

  • Twinrix
  
Measles/Mumps/Rubella
Therapeutics that prevent or treat viral infections by producing or artificially increasing immunity to measles, mumps, and rubella.

Buyer Products:

  • Priorix
  
Measles/Mumps/Rubella/Varicella
Therapeutics that prevent or treat viral infections by producing or artificially increasing immunity to measles, mumps, rubella, and varicella.

Buyer Products:

  • Priorix-Tetra
  
Single Target  
Hepatitis A
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to the Hepatitis A virus.

Buyer Products:

  • Havrix (Hepatitis A Vaccine, Inactivated)
  
Hepatitis B
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to the Hepatitis B virus.

Buyer Products:

  • Fendrix
  • Engerix-B
  
Hepatitis E
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to the Hepatitis E virus.

Buyer Products:

  • Hepatitis E Vaccine
  
Herpes Simplex
Therapeutics that prevent or treat viral infections characterized by vesicular eruption by producing or artificially increasing immunity to the Herpes Simplex virus.

Buyer Products:

  • Simplirix
  
Influenza (Flu)
Therapeutics that prevent or treat viral infections of the respiratory tract by producing or artificially increasing immunity to the Influenza virus.

Buyer Products:

  • FluLaval (Influenza Virus Vaccine)
  • Fluarix (Influenza Vaccine, Inactivated Split Virion)
  • H5N1 Pandemic Flu Vaccine
  
Papillomavirus
Therapeutics that prevent or treat viral infections characterized by the proliferation of epithelial cells, leading to the formation of warts and possibly other related diseases such as cervical pre-cancers and cervical cancer.

Buyer Products:

  • Cervarix (HPV16/HPV18 Vaccine)
  
Rabies
Therapeutics that prevent or treat viral infections that infect brain cells by producing or artificially increasing immunity to the rabies virus.

Buyer Products:

  • Rabies Vaccine Absorbed
  
Rotavirus
Therapeutics that prevent or treat viral infections that cause severe dehydrating diarrhea in children by producing or artificially increasing immunity to the rotavirus.

Buyer Products:

  • Rotarix (Rotavirus Vaccine)
  
Varicella-Zoster Virus (Chicken Pox)
Therapeutics that prevent or treat viral infections that cause a blistery red rash by producing or artificially increasing immunity to the Varicella Zoster virus.

Buyer Products:

  • Varilrix
  
Musculoskeletal System
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Relacatib
  • 681323 (p38 Kinase Inhibitor)
  • Avandia (Rosiglitazone Maleate)
  • 751689
  • LymphoStat-B (Belimumab)
  • 768974 (Parathyroid Hormone Agonist)
  • 856553 (p38 Kinase Inhibitor)
  • Rosiglitazone XR
  • Radafaxine
  • 274150 (Selective iNOS Inhibitor)

Target Products:

  • R1487 (Kinase Inhibitor)
  • R1295 (Integrin Antagonist)
  • R1164
  • Humanized Anti-CD20 (Ocrelizumab)
  • R1599
  • BR3-FC (Soluble BAFF Antagonist) Protein Therapeutic
  • R1594 (Anti-CD20 Molecule )
  • ED-71 (Vitamin D Derivative)
  • CHS 13340 (Recombinant Parathyroid Hormone)
  • R1503 (Kinase Inhibitor)
  • Rituxan (Rituximab)
  • Raptiva (Efalizumab)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1628
  
Skeletal Disorders
Bone Disorders
Osteoporosis
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts.

Buyer Products:

  • Boniva (Ibandronate Biphosphonate)

Target Products:

  • Boniva (Ibandronate Biphosphonate)
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts while not stimulating the endometrial lining of the uterus.

Target Products:

  • Evista (Raloxifene Hydrochloride)
  
Joint Disorders
Ankylosing Spondylitis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by inhibiting cyclooxygenase activity.

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Osteoarthritis (OA)
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Relafen (Nabumetone)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
Rheumatoid Arthritis (RA)
Analgesics
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Relafen (Nabumetone)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Rituxan (Rituximab)
  • Actemra (Tocilizumab)
  
Neurology
Neurological Disorders
Epilepsy
Partial Seizures  
Complex  
Adjunctive Therapy  
Sodium Channel Blocking Agents
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Buyer Products:

  • Lamictal (Lamotrigine)
  
Monotherapy  
Sodium Channel Blocking Agents
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Buyer Products:

  • Lamictal XR (Lamotrigine)
  • Lamictal (Lamotrigine)
  
Simple  
Monotherapy  
Sodium Channel Blocking Agents
Therapeutics that treat simple partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses.

Buyer Products:

  • Lamictal XR (Lamotrigine)
  
Primary Generalized Seizures  
Absence (Petit Mal)  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Akinetic Pattern  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Myoclonic  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevent nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevents nerve activation.

Target Products:

  • Klonopin (Clonazepam)
  
Headaches  
Chronic  
Analgesics/Antipyretics/Antihistamines
Therapeutics that treat headaches through management of pain, fever and the proliferation of molecules that causes inflammation.

Buyer Products:

  • Goody's PM Powder For Pain With Sleeplessness
  
Cluster  
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat Cluster Headaches by blocking the receptor that binds with the neurotransmitter, serotonin.

Buyer Products:

  • Imitrex Injection (Sumatriptan Succinate)
  
Vascular (Migraine)  
Acute Treatments  
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Selective Serotonin Receptor Agonists
Therapeutics that treat vascular headaches by inhibiting the action of cyclooxygenase, which is an inflammatory substance, as well as stimulating the serotonin receptor.

Buyer Products:

  • Trexima (Naproxen/Sumatriptan)
  
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat vascular/migraine headaches by stimulating the receptor that binds with the neurotransmitter, serotonin.

Buyer Products:

  • Amerge (Naratriptan Hydrochloride)
  • Imitrex Injection (Sumatriptan Succinate)
  • Imitrex Nasal Formulation (Sumatriptan)
  • Imitrex (Sumatriptan Succinate)
  
Neuromuscular Disorders  
Parkinson`s Disease (PD)  
Monotherapy  
Dopamine Receptor Agonists
Therapeutics that treat the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on the neurons.

Buyer Products:

  • ReQuip (Ropinirole Hydrochloride)
  • ReQuip CR (Ropinirole Hydrochloride) Once-Daily
  
Restless Leg Syndrome  
Dopamine Receptor Agonists
Therapeutics that treat Restless Leg Syndrome by stimulating dopamine activity.

Buyer Products:

  • ReQuip (Ropinirole Hydrochloride)
  • Requip XR
  
Singultus (Hiccups)  
Dopamine Receptor Blocking Agents
Therapeutics that treat hiccups by blocking the action of the dopamine receptors in the brain and also peripherally acting on the vagus nerve, which may be responsible for the involuntary contractions.

Buyer Products:

  • Thorazine (Chlorpromazine)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 372475
  • 742457 (5HT6 Antagonist)
  • Casopitant (NK-1 Receptor Antagonist)
  • Rosiglitazone XR
  • 163090
  • GSK649868 (Orexin Antagonist)
  • 876008 (CRF1 Antagonist Back-Up Compound)
  • 705498 (Vanilloid Receptor 1 Antagonist)
  • 773812 (Mixed 5HT/Dopaminergic Antagonist)
  • 823296 (NK1 Antagonist)
  • Avandia (Rosiglitazone Maleate)
  • 274150 (Selective iNOS Inhibitor)
  • 406725 (Gap Junction Blocker)
  • 644784 (COX-2 Inhibitor)
  • Radafaxine
  • 683699 (VLA4 Antagonist)
  • Vestipitant/Paroxetine
  • Talnetant (NK-3 Receptor Antagonist)

Target Products:

  • Rituxan (Rituximab)
  • MT 500 (GPCR Modulator)
  • R1204 (GPCR Modulator)
  • R673 (GPCR Modulator)
Psychiatric Disorders
Anxiety
Generalized Anxiety Disorder (GAD)
Dopamine Receptor Blocking Agents
Therapeutics that treat anxiety by blocking dopamine receptors.

Buyer Products:

  • Compazine (Prochlorperazine)
  • Stelazine (Trifluoperazine Hydrochloride)
  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Valium (Diazepam)
  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat anxiety by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)
  
Obsessive Compulsive Disorder (OCD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Anxiety by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)
  
Panic Disorder
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Klonopin (Clonazepam)
  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat panic disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)
  • Paxil CR (Paroxetine Hydrochloride)
  
Post-Traumatic Stress Disorder (PTSD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat post traumatic stress disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)
  
Social Anxiety Disorder (SAD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)
  
Childhood/Adolescent Disorders  
Attention Deficit Disorder (ADD)/Attention Deficit Hyperactivity Disorder (ADHD)  
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving hyperactivity in children due to an abnormally short attention span.

Buyer Products:

  • Dexedrine (Dextroamphetamine Sulfate)
  
Mood Disorders  
Bipolar Disorders (Manic Depressive Disorders)  
Dopamine Receptor Blocking Agents
Therapeutics that treat bipolar disorders by blocking the dopamine receptors.

Buyer Products:

  • Thorazine (Chlorpromazine)
  
Lithium-Based Agents
Therapeutics that treat bipolar disorders by decreasing the concentrations of neurotransmitters.

Buyer Products:

  • Eskalith/Eskalith CR (Lithium Carbonate)
  
Sodium Channel Blocking Agents
Therapeutics that treat bipolar disorders by blocking the sodium channels which in turn prevents the conductance of nerve impulses.

Buyer Products:

  • Lamictal (Lamotrigine)
  
Depression  
Dopamine Receptor Blocking Agents
Therapeutics that treat depression by blocking the dopamine receptors.

Buyer Products:

  • Compazine (Prochlorperazine)
  
Monoamine Oxidase (MAO) Inhibitors
Therapeutics that treat depression by inhibiting the activity of monoamine oxidase, which degrades neurotransmitters.

Buyer Products:

  • Parnate (Tranylcypromine Sulfate)
  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat depression by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)
  • Paxil CR (Paroxetine Hydrochloride)
  
Serotonin Receptor Agonists
Therapeutics that treat depression by stimulating the serotonin receptors.

Buyer Products:

  • Variza (Gepirone ER)
  
Serotonin/Norepinephrine Reuptake Inhibitors
Therapeutics that treat depression by inhibiting the neuronal uptake of serotonin and norepinephrine.

Buyer Products:

  • Wellbutrin IR/SR (Bupropion Hydrochloride)
  • Wellbutrin XL (Bupropion Hydrochloride)
  
Premenstrual Dysphoric Disorders  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat premenstrual dysphoric disorders by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)
  • Paxil (Paroxetine Hydrochloride)
  
Schizophrenia  
Dopamine Receptor Blocking Agents
Therapeutics that treat schizophrenia by blocking the dopamine receptors.

Buyer Products:

  • Thorazine (Chlorpromazine)
  
Sleep Disorders  
Insomnia  
Antihistamines
Therapeutics that treat insomnia by preventing the functions of histamine on tissues.

Buyer Products:

  • Sominex Original Formula (Diphenhydramine HCl)
  • Nytol Quickgels Softgels (Diphenhydramine Hydrochloride)
  
Antihistamines/Analgesics/Antipyretics
Therapeutics that treat insomnia by preventing the functions of histamine on tissues as well as treating pain and suppressing fever.

Buyer Products:

  • Goody's PM Powder For Pain With Sleeplessness
  
Narcolepsy  
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving hronic and sudden daytime sleepiness.

Buyer Products:

  • Dexedrine (Dextroamphetamine Sulfate)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1576 (GPCR Modulator)
  • R1067 (GPCR Modulator)
  • R641
  • R1450
  
Obstetrics/Gynecology  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of female reproductive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 221149
  
Oncology
Breast Cancer
Localized  
Monoclonal Antibodies
Therapeutics that treat breast cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
  • Herceptin (Trastuzumab)
  
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage breast cancers that have spread beyond their original tumor site by inhibiting the production of DNA.

Target Products:

  • Xeloda (Capecitabine)
  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of breast cancer cells and inhibit the cancer cells' growth and induce their death.

Target Products:

  • Avastin (Bevacizumab)
  • Herceptin (Trastuzumab)
  
Tyrosine Kinase Inhibitors
Therapeutics that treat breast cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Tykerb (Lapatinib Ditosylate)
  
Dermatology  
Kaposi`s Sarcoma  
Interferons
Therapeutics that treat and manage cancers of spindle cells by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Digestive System  
Colon Cancer/Colorectal Cancer  
Metastatic  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage colorectal tumors that have spread beyond their original tumor site by inhibiting the production of DNA.

Target Products:

  • Xeloda (Capecitabine)
  
Monoclonal Antibodies
Therapeutics that treat colorectal cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
  
Pancreatic Cancer  
Metastatic  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Target Products:

  • Tarceva (Erlotinib)
  
Hematology
Leukemia (White Blood Cell Cancer)
Lymphoid
Acute  
Lymphoblastic  
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers of immature lymphocytic cells by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Arranon (Nelarabine)
  
Chronic  
Hairy Cell  
Interferons
A recombinantly produced protein normally produced by the body to fight viral infection used to treat and manage a slowly progressing cancer of lymphoid cells characterized by numerous irregular cytoplasmic projections.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Lymphocytic (CLL)  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of leukemia cells and thereby induce their death.

Target Products:

  • Rituxan (Rituximab)
  
Myeloid
Acute
Myeloblastic  
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers affecting immature cells of the bone marrow by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Tabloid (Thioguanine)
  
Myelogenous (AML)  
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers of the myelogenous cellsby interfering with nucleic acid biosynthesis.

Buyer Products:

  • Tabloid (Thioguanine)
  
Promyelocytic (APL)  
Retinoids/Vitamin A Analogs
Therapeutics that treat acute promyelocytic leukemia by helping in cell differentiation as well as decreasing proliferation of cells.

Target Products:

  • Vesanoid (Tretinoin)
  
Chronic  
Myelogenous (CML)  
Interferons
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by providing a naturally occurring protein that stimulates the immune system.

Target Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Palliative Agents  
Alkylating Agents  
Alkylsulfonates
Therapeutics that treat and manage cancers of myeliod cells by cross-linking and breaking DNA strands which ultimately leads to cell death.

Buyer Products:

  • Myleran (Busulfan)
  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancers of myeliod cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
  
Lymphoma (Lymphatic Cancer)
Hodgkin`s Disease  
Palliative Agents  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage lymphoma characterized by the presence of Reed-Sternberg cells by interacting with DNA and inhibiting cell division but that are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
  
Non-Hodgkin`s Lymphoma (NHL)
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage lymphomas of B-cells and T-cells by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Arranon (Nelarabine)
  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of lymphoma cells and thereby induce their death.

Target Products:

  • Rituxan (Rituximab)
  
Palliative Agents  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage lymphomas of B-cells and T-cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
  
Radioactive Agents/Monoclonal Antibodies
Therapeutics that utilize a monoclonal antibody to target a local dose of radiation to lymphoma cells in order to induce their death.

Buyer Products:

  • Bexxar (Iodine I-131/Tositumomab)
  
Multiple Myeloma (Plasma Cell Cancer)  
Palliative Agents  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancers of mature antibody producing white blood cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Alkeran (Melphalan Hydrochloride)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • Her2/Neu Breast Cancer Vaccine
  • Ispinesib/SB-715992
  • Iboctadekin
  • Cervarix (HPV16/HPV18 Vaccine)
  • SB-743921 (Kinesin Spindle Protein Inhibitor)
  • Mage-A3 (Cancer Vaccine)
  • Pazopanib
  • Tykerb (Lapatinib Ditosylate)
  • Relacatib
  • SB 251353 (CXC Chemokine)
  • P501 (Prostate Cancer Vaccine)

Target Products:

  • R1668 (E2F Modulator)
  • AS1404
  • E2F Activating Compound
  • R1594 (Anti-CD20 Molecule )
  • KOS-1584/R1465 (Epothilone)
  • CAL (Anti-PTHrP Monoclonal Antibody)
  • CHC 12103 (Polyglutamate TXL)
  • AHM (Anti-HM 1.24 Monoclonal Antibody)
  • R1536 (Enzyme Inhibitor)
  • R1550 (Monoclonal Antibody)
  • R1492 (Enzyme Inhibitor)
  • R1564/DMXAA (Vascular Targeting Agent)
  • Therex
  • Therafab
  • Pemtumomab/R1549
  • Diflomotecan (Topoisomerase Inhibitor I)
  • Trastuzumab-DM1
  • Tarceva (Erlotinib)
  • R1273 (Monoclonal Antibody)
  • PRO64553 (Anti-CD40 Antibody)
  • Avastin (Bevacizumab)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Target Products:

  • R1491 (Angiogenesis Inhibitor)
  • R1453 (Enzyme Inhibitor)
  • R1559 (Enzyme Inhibitor)
  • P53 Pathway Activators
  • PRO1762
  • R1630 (Enzyme Inhibitor)
  • R547 (Enzyme Inhibitor)
  • 2H7
  • R1454 (Enzyme Inhibitor)
  • BN80927 (Topoisomerase I/II Inhibitor)
  
Respiratory System/Thoracic
Lung Cancer
Non Small Cell Lung Cancer (NSCLC)
Antimicrotubule Agents
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the normal function of microtubules, thus inhibiting cell division.

Buyer Products:

  • Navelbine (Vinorelbine Tartrate)
  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the tyrosine kinase enzyme by switching off the signals from the epidermal growth factor receptors.

Target Products:

  • Tarceva (Erlotinib)
  
Monoclonal Antibodies
Therapeutics that treat lung cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
  
Small Cell Lung Cancer (SCLC)  
Topoisomerase I Inhibitors
Therapeutics that treat and manage cancers of the small cells in the lung by inhibiting a specific enzyme, topoisomerase I, which is needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin (Topotecan Hydrochloride)
  
Urology
Cervical Cancer  
Localized  
Papillomavirus Vaccines
Therapeutics that are meant to promote an immune response against the Papillomavirus that are involved in the pathogenesis of cervical cancer.

Buyer Products:

  • Cervarix (HPV16/HPV18 Vaccine)
  
Topoisomerase I Inhibitors
Therapeutics that treat and manage cancers of the cervix by inhibiting a specific enzyme, topoisomerase I, which is needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin (Topotecan Hydrochloride)
  
Kidney Cancer (Renal Cell Carcinoma)
Metastatic
Monoclonal Antibodies
Therapeutics that treat kidney cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Avastin (Bevacizumab)
  
Tyrosine Kinase Inhibitors
Therapeutics that treat kidney cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Tykerb (Lapatinib Ditosylate)
  
Ovarian Cancer
Adenocarcinoma
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancer of cells lining the ovary by interacting with DNA and inhibiting cell division.

Buyer Products:

  • Alkeran (Melphalan Hydrochloride)
  
Monoclonal Antibodies
Therapeutics that treat ovarian cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Target Products:

  • Pemtumomab/R1549
  
Metastatic  
Topoisomerase I Inhibitors
Therapeutics that treat and manage ovarian cancers that have spread beyond their original tumor site by inhibiting a specific enzyme, topoisomerase I, needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin (Topotecan Hydrochloride)
  
Prostate Cancer  
Localized  
5-Alpha Reductase Inhibitors
Therapeutics that treat prostate cancer by inhibiting the formation of Dihydrotestosterone from testosterone.

Buyer Products:

  • Avodart (Dutasteride)
  
Ophthalmology
Degenerative Disorders  
Macular Degeneration (AMD)  
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular degeneration by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Target Products:

  • Lucentis (Ranibizumab)
  
Retinitis  
AIDS-Related Cytomegalovirus (CMV) Retinitis  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of eye disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 267268

Target Products:

  • Lucentis (Ranibizumab)
Pain Management
Anesthesia  
General (Systemic)  
Adjunctive  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that result in anesthesia by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Versed (Midazolam)
  
Reversal  
Gamma-Aminobutyric Acid (GABA) Receptor Antagonists
Therapeutics that reverse general anesthesia by competitively inhibiting benzodiapizines at the GABA receptors, thus reducing their effect and reversing the anesthesia.

Target Products:

  • Romazicon (Flumazenil)
  
Non-Narcotics
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Ecotrin (Enteric Coated Acetylsalicyclic Acid)

Target Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  • Toradol (Ketorolac Tromethamine)
  • Aleve (Naproxen Sodium)
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Analgesics/Antipyretics
Therapeutics that treat pain and fever by inhibiting the action of prostaglandins.

Buyer Products:

  • Goody's Body Pain Formula Powder (Aspirin / Acetaminophen)
  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Analgesics/Antipyretics/Caffeine
Therapeutics that treat pain and fever by inhibiting the action of prostaglandins.

Buyer Products:

  • Goody's Extra Strength Headache Powder (Asprin / Acetaminophen / Caffeine)
  • Goody's Extra Strength Pain Relief Tablets (Aspirin/Acetaminophen/Caffeine)
  • BC Powder (Aspirin / Salicylamide / Caffeine)
  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Decongestants
Therapeutic combinations that produce insensibility or numbness through the inhibition of prostoglandins while also preventing nasal decongestion.

Target Products:

  • Aleve Cold & Sinus (Naproxen/Pseudoephedrine)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of pain in early stages of clinical research where human subject is involved.

Buyer Products:

  • 406725 (Gap Junction Blocker)
  • 644784 (COX-2 Inhibitor)
  • 842166 (Non-Cannabinoid CB2 Agonist)
  • Radafaxine

Target Products:

  • Bondronat (Ibandronate)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of pain in very early stages of research where no human subject is involved.

Buyer Products:

  • VX-409 (Selective Sodium Channels Modulator)
  
Respiratory System
Lower Respiratory Tract Disorders (Lung Disorders)
Asthma
Acute Treatments  
Bronchodilators  
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Non-CFC Ventolin (Albuterol)
  • Ventolin (Albuterol)
  • Non-CFC Serevent (Salmeterol Xinafoate)
  • Serevent (Salmetrol Xinafoate)
  
Prophylactic Treatments
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat asthma by reducing inflammation in the lungs with steroids and that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Advair HFA Inhalation Aerosol (Fluticasone Propionate/Salmeterol)
  • Seretide (Salmeterol/Fluticasone)
  • Advair Diskus (Salmeterol/Fluticasone)
  
Monoclonal Antibodies
Therapeutics that treat asthma with monoclonal antibodies.

Target Products:

  • Xolair (Omalizumab)
  
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat asthma by reducing inflammation in the lung passages with steroids.

Buyer Products:

  • Beclovent (Beclomethasone Dipropionate)
  • Flovent (Fluticasone Propionate)
  • Flovent HFA Inhalation Aerosol (Inhaled Fluticasone Propionate HFA)
  
Bronchitis  
Acute Treatments  
Bronchodilators  
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Ventolin (Albuterol)
  • Non-CFC Ventolin (Albuterol)
  
Bronchospasm  
Bronchodilators  
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Non-CFC Ventolin (Albuterol)
  • Serevent (Salmetrol Xinafoate)
  • Ventolin (Albuterol)
  
Chronic Obstructive Pulmonary Disease (COPD)  
Acute Treatments  
Bronchodilators  
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Non-CFC Serevent (Salmeterol Xinafoate)
  • Non-CFC Ventolin (Albuterol)
  • Ventolin (Albuterol)
  • Serevent (Salmetrol Xinafoate)
  
Phosphodiesterase Inhibitors (PDE Inhibitors)
Therapeutics that inhibit the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in relaxing smooth muscles in the lungs.

Buyer Products:

  • Ariflo (Cilomilast)
  
Prophylactic Treatments  
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that are used to prevent COPD attacks by preventing inflammation and stimulating beta adrenergic receptors.

Buyer Products:

  • Advair Diskus (Salmeterol/Fluticasone)
  
Phosphodiesterase Inhibitors (PDE Inhibitors)
Therapeutics that are used to prevent COPD attacks by inhibiting the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in relaxing smooth muscles in the lungs.

Buyer Products:

  • Ariflo (Cilomilast)
  
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that are used to prevent COPD attacks by reducing inflammation in the lung passages with steroids.

Buyer Products:

  • Flovent (Fluticasone Propionate)
  
Respiratory Distress Syndrome (RDS)  
Surfactants
Therapeutics that treat RDS by modifying alveolar surface tension and thereby stabilizing the alveoli.

Buyer Products:

  • Exosurf Neonatal (Colfosceril Palmitate/Cetyl Alcohol/Tyloxapol)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 856553 (p38 Kinase Inhibitor)
  • 678007 (Long Acting Beta 2 Agonist)
  • 685698 (Glucocorticoid Agonist)
  • 159797 (Long-Acting Beta 2 Agonist)
  • 159802 (Long-Acting Beta2 Agonist)
  • 799943
  • GSK642444 (Long Acting Beta Agonist)
  • 233705
  • 961081
  • 597901 (Long Acting Beta 2 Agonist)
  • 256066
  • 870086
  • Veramyst (Intranasal Fluticasone Furoate)/Formely Allermist
  • 681323 (p38 Kinase Inhibitor)
  • Mepolizumab

Target Products:

  • R448
  • R667 (Nuclear Receptor)
  • R411 (Integrin Antagonist)
  • R1295 (Integrin Antagonist)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1456 (Nuclear Receptor)
  
Upper Respiratory Tract Disorders  
Coughs/Colds  
Anticholinergic Agents/Opioids
Therapeutics that treat coughs and colds by relieving pain and fever as well as suppressing cough.

Buyer Products:

  • Contac Cough & Sore Throat (Dextromethorphan Hydrobromide/Acetaminophen)
  
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Contac 12 Hour Allergy (Clemastine Fumarate)
  
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and reduces the amount of mucous build up.

Buyer Products:

  • Contac 12 Hour/Contac Maximum Strength 12 Hour Caplets (Chlorpheniramine Maleate/Phenylpropanolamine Hydrochloride)
  
Antihistamines/Decongestants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by suppressing inflammation, reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Allergy/Sinus Night Capsules (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
  • Contac Severe Cold And Flu Caplets Maximum Strength (Phenylpropanolamine HCl/Chlropheniramine Maleate/ Acetaminophen/ Dextromethorphan Hydrobromide)
  
Antihistamines/Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by suppressing inflammation, reducing mucous build up, relieving or preventing coughs, relieving pain, and reducing fever.

Buyer Products:

  • Contac Severe Cold Formula Night Strength (Doxylamine Succinate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen/Alcohol)
  • Contac Severe Cold & Flu Hot Medicine (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Night Cold & Flu Caplets (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Severe Cold Formula Capsules (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  
Decongestants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Allergy Sinus Day Caplets/Contac Non-Drowsy Formula Sinus Caplets (Pseudoephedrine Hydrochloride/Acetaminophen)
  
Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing coughs and relieving pain and fever.

Buyer Products:

  • Contac Day Cold & Flu Caplets/Contac Severe Cold & Flu Non-Drowsy Caplets (Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Jr. Children's Cold Medicine (Phenylpropanolamine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  
Decongestants/Antitussives/Expectorants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing the cough, helping in the ejection of mucous and helping relieve fever and pain.

Buyer Products:

  • Contac Cough & Chest Cold (Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Guaifenesin/Acetaminophen)
  
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress the inflammation in the upper respiratory tract with steroidal compounds.

Buyer Products:

  • Beconase AQ (Beclomethasone Dipropionate, Monohydrate)
  
Nasal Dryness  
Moisturizing Agents
Therapeutics that treat nasal dryness by providing moisture to the nasal passages.

Buyer Products:

  • Breathe Right Snore Relief Throat Spray
  • Breathe Right Vapor Shot
  • Breathe Right Saline Spray
  
Surgery
Cardiovascular System  
Complications  
Peripheral Arterial Occlusion  
Thrombolytic Agents
Therapeutics that treat diseases of the blood vessels outside the heart by dissolving blood clots.

Target Products:

  • Cathflo Activase (Alteplase)
  
Digestive System  
Post-Operative Ileus/Constipation  
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Entereg (Alvimopan)
  
General  
Complications  
Nausea/Vomiting  
Serotonin Receptor Antagonists
Therapeutics that prevent or treat post surgical nausea and vomiting by blocking the receptors that bind serotonin, a neurotransmitter.

Buyer Products:

  • Zofran/Zofran ODT (Ondansetron Hydrochloride)
  
Restlessness/Apprehension  
Dopamine Receptor Blocking Agents
Therapeutics that treat the nervousness which precedes surgery by blocking the receptor that binds the neurotransmitter, dopamine.

Buyer Products:

  • Thorazine (Chlorpromazine)
  
Musculoskeletal System  
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by blocking an enzyme involved in the clotting process.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
  
Toxicology
Chemical Poisoning  
Digoxin  
Digoxin Binding Agents
Therapeutics that treat toxicity due to ingestion of excessive digoxin by competitively binding to digoxin, making them unavailable for binding at their site of action on cells in the body.

Buyer Products:

  • Digibind (Digoxin Immune Fab)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of toxicity in early stages of clinical research where human subject is involved.

Buyer Products:

  • 468816 (Glycine Receptor Antagonist)
  
Substance Abuse
Withdrawal
Alcohol  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Target Products:

  • Valium (Diazepam)
  
Nicotine (Smoking Cessation)  
Nicotinic Receptor Agonists
Therapeutics that treat nicotine withdrawal by activating nicotine receptors thus reducing cravings for nicotine.

Buyer Products:

  • Nicorette (Nicotine Polacrilex Gum)
  • NicoDerm CQ (Nicotine Transdermal System)
  
Serotonin/Norepinephrine Reuptake Inhibitors
Therapeutics that increase the concentration of several neurotransmitters in the brain by inhibiting their uptake.

Buyer Products:

  • Zyban (Bupropion Hydrochloride)
  
Transplantation  
Bone Marrow  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Cytovene (Ganciclovir)
  
Heart  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that help manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • CellCept (Mycophenolate Mofetil)
  
Hepatic (Liver)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Cytovene (Ganciclovir)
  • Valcyte (Valganciclovir Hydrochloride)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • CellCept (Mycophenolate Mofetil)
  
Lung  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Cytovene (Ganciclovir)
  • Valcyte (Valganciclovir Hydrochloride)
  
Pancreas  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the management of rejection and infection in early stages of clinical research where human subject is involved.

Target Products:

  • ISATX247 Trans
  • R1524 (Calcineurin Inhibitor)
  • Raptiva (Efalizumab)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • VAL (Liver Regenerator)
  
Renal (Kidney)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Target Products:

  • Cytovene (Ganciclovir)
  • Valcyte (Valganciclovir Hydrochloride)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • CellCept (Mycophenolate Mofetil)
  
Monoclonal Antibodies
Protein-based therapeutics that target specific substances like proteins.

Target Products:

  • Zenapax (Daclizumab)
  
Urology
Male Genital Disorders  
Penile  
Erectile Dysfunction (Impotence)  
Phosphodiesterase Type 5 Inhibitors (PDE-5 Inhibitors)
Therapeutics that inhibit the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in dilating the blood vessels in the penis.

Buyer Products:

  • Levitra (Vardenafil Hydrochloride)
  
Prostate  
Benign Prostate Hyperplasia (BPH)  
5-Alpha Reductase Inhibitors
Therapeutics that inhibit the transformation of testosterone into dihydrotestosterone (DHT), a substance that causes enlargement of the prostate.

Buyer Products:

  • Avodart (Dutasteride)
  • Avodart (Dutasteride) Plus Alpha Blocker
  
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that increase blood flow by acting on the alpha adrenergic receptors thus causing the smooth muscle in the prostate to relax and decreasing the constriction on the urinary tract.

Buyer Products:

  • Avodart (Dutasteride) Plus Alpha Blocker
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Dutasteride/Testosterone
  • Casopitant (NK-1 Receptor Antagonist)
  • Solabegron
  • 366074 (Potassium Channel Opener)

Target Products:

  • R701 (GPCR Antagonist)
  • R450 (GPCR Modulator)
  • R1484 (GPCR Modulator)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1554 (GPCR Antagonist)
  • R873 (GPCR Agonist)
  • R1437 (GPCR Antagonist)
  
Urological Disorders
Bladder  
Urinary Frequency/Urge Incontinence  
Muscarinic Receptor Antagonists
Therapeutics that treat the inability to control urinary excretory functions by blocking the action of choline and other cholinergic agents by binding to the muscarinic receptor.

Buyer Products:

  • Vesicare (Solifenacin Succinate)
  
Kidney (Renal)  
Chronic Renal Failure (CRF)  
Complications  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat the condition resulting from the scarcity of red blood cells by inducing the production of red blood cells.

Target Products:

  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
  
Edema  
Loop Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine.

Target Products:

  • Bumex (Bumetanide)
  • Demadex (Torsemide)
  
Weight Management
Obesity
Lipase Inhibitors
Therapeutics that reduce the absorption of fat by inhibiting production of lipase, which is an enzyme that helps breaking down fat in the food.

Buyer Products:

  • Xenical (Orlistat)
  • Alli (Orlistat)

Target Products:

  • Xenical (Orlistat)
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 856464 (Melanin Concentrating Hormone Agonist)
  • Radafaxine
  • 869682

Target Products:

  • R1065 (GPCR Modulator)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in very early stages of research where no human subject is involved.

Target Products:

  • R1496 (GPCR Modulator)
  
Wound Management  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of wounds in very early stages of research where no human subject is involved.

Target Products:

  • Vascular Endothelial Growth Factor
  
Medical Devices
Clinical Diagnostics
Chemistry  
Analyzers  
Blood Gas
Analyzers used to measure blood gases for diagnostic purposes.

Target Products:

  • Roche Diagnostics AVL Compact 1-3
  • Roche Diagnostics AVL 988 Series
  • Roche Diagnostics OMNI Series
  
Discrete  
Limited Assay
Discrete analyzers with limited test menu.

Target Products:

  • Roche Diagnostics AVL 9180 Series
  • Roche Diagnostics OMNI Series
  
Multiple Assay
Multi-System analyzers designed for high throughput generally used in high volume clinical laboratories.

Target Products:

  • Roche Diagnostics Roche/Hitachi 902/912
  • Roche Diagnostics Reflotron Series
  • Roche Diagnostics Cobas Integra Series
  
Home Testing  
Cholesterol
Home test kits which test for cholesterol levels in patient blood.

Target Products:

  • Roche Diagnostics Accutrend System
  • Roche Diagnostics Accu-Chek Plus
  
Glucose  
Invasive
Devices that generally use blood samples for testing and require a needlestick or pin-prick.

Target Products:

  • Roche Diagnostics Accu-Chek Instant DM
  • Roche Diagnostics Accu-Chek Simplicity
  • Roche Diagnostics Accu-Chek Active Meter
  • Roche Diagnostics Accu-Chek Compact Meter
  • Roche Diagnostics Accu-Chek Advantage/Advantage II/Sensor Meter
  • Roche Diagnostics Accu-Chek Complete/Sensor Complete Meter
  • Roche Diagnostics Accu-Chek Aviva
  • Roche Diagnostics Accu-Chek Plus
  
Test Strips
Specific glucose test devices used with glucose monitors.

Target Products:

  • Roche Diagnostics Accu-Chek Advantage Test Strips
  • Roche Diagnostics Glucotrend Strips
  • Roche Diagnostics Accu-Chek Simplicity Test Strips
  • Roche Diagnostics Accu-Chek Compact Test Drums
  • Roche Diagnostics Accu-Chek Comfort Curve/Sensor Comfort/Advantage Comfort/Advantage II Test Strips
  • Roche Diagnostics Accu-Chek Active Test Strips
  • Roche Diagnostics Accu-Chek Go
  
Point of Care Testing  
Critical Care Analysis  
Analyzers
Chemistry analyzers which may be used for the chemical analysis of body fluids and designed for use at the bedside during the course of patient care.

Target Products:

  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Elecsys 1010
  
Test Cartridges
Specific analyte test devices used in conjunction with critical care chemistry analyzers.

Target Products:

  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Elecsys 1010
  
Glucose Monitoring  
Invasive  
Continuous Analysis
Glucose test devices which measure patient glucose levels on a continual basis.

Target Products:

  • GlucOnline Microdialysis System
  
Random Analysis
Glucose test devices which measure patient glucose levels as a blood sample is obtained.

Target Products:

  • Roche Diagnostics AccuData GTS/AccuData HDM
  • Roche Diagnostics Accu-Chek Inform System
  
Kits  
Cardiac
Test kits used to aid in the diagnosis of heart conditions.

Target Products:

  • Roche Diagnostics Cardiac D-Dimer
  
Reagents  
Calibrators  
Routine Analyte  
Multiple
Calibrators which contain multiple specific analytes used to establish the accuracy of chemistry analyzers.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Single
Calibrators which contain a specific analyte used to establish the accuracy of chemistry analyzers.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Controls  
Routine
Controls used to test the accuracy of discrete chemistry test systems.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Test Kits  
Pharmacogenetic
Test kits designed to determine individuals' reaction to specific medications based on their specific genes.

Target Products:

  • Roche Diagnostics AmpliChip CYP450 Test
  
Hemostasis/Coagulation  
Analyzers  
Automated
Automated coagulation analyzers.

Target Products:

  • Roche Diagnostics Stago Sta Compact
  • Roche Diagnostics Stago Sta R
  
Reagents  
Test Kits  
Prothrombin Time
Reagents used to perform prothrombin time assays.

Target Products:

  • Roche Diagnostics CoaguChek Series
  
Immunoassays
Analyzers  
Autoimmune
Analyzers used to perform autoimmune testing.

Target Products:

  • Roche Diagnostics COBAS AmpliPrep System
  • Roche Diagnostics COBAS AMPLICOR Analyser
  
Multiple Assay
Immunoassay analyzer designed to perform multiple assays over multiple modalities.

Target Products:

  • Roche Diagnostics Elecsys 1010
  • Roche Diagnostics E170
  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Cobas Core II
  
Reagents
Calibrators  
Therapeutic Drugs
Calibrators used in the measurement of therapeutic drugs.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Toxicology/Abuse Drugs
Calibrators used in the measurement of drugs of abuse.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Controls  
Therapeutic Drugs
Controls which contain known concentrations of specific therapeutic drugs used to verify the performance of therapeutic drug testing systems.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Test Kits
Allergy  
Specific Allergen
Allergy test kits specific to a single allergen.

Buyer Products:

  • T.R.U.E. Test
  
Bacterial  
Chlamydia
Immunoassay kits which test for current or previous infection caused by the Chlamydia organism.

Target Products:

  • Roche Diagnostics COBAS AMPLICOR CT/NG Test/AMPLICOR CT/NG Test
  
Tuberculosis
Immunoassay test kits which quantitatively measure tuberculosis antibody in plasma or serum.

Target Products:

  • Roche Diagnostics Amplicor M. tuberculosis Test
  
Radioimmunoassays  
Cancer Marker
Radioimmunoassay test kits which measure for cancer markers in plasma or serum.

Target Products:

  • Roche Diagnostics Cobas Core Reagent Series
  
Cardiac
Radioimmunoassay test kits which measure for analytes associated with heart disease in plasma or serum.

Target Products:

  • NT-proBNP
  
Special/Immuno Chemistry  
Cancer Marker  
Breast
Diagnostic assay used to detect specific breast tumor or cancer markers.

Target Products:

  • BCM 18 (Breast Cancer Marker)
  
Colorectal (Colon)
Diagnostic assay used to detect specific colorectal (colon) tumor or cancer markers.

Target Products:

  • Roche Diagnostics hemo FEC
  
Cardiac  
Myocardial Infarction/Heart Failure  
Myoglobin
Immunoassay test kits which quantitatively measure for myoglobin in plasma or serum.

Target Products:

  • Roche Diagnostics Cardiac Reader
  
Troponin
Immunoassay test kits which quantitatively measure for troponin in plasma or serum.

Target Products:

  • Roche Diagnostics Cardiac Reader
  • Roche Diagnostics TROPT Sensitive
  
Therapeutic Drugs
Immunoassay test kits which quantitatively measure for therapeutic drugs in serum or urine using automated instrumentation..

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  
Toxicology/Abuse Drugs  
Multiple Drug Kit
Immunoassay test kits which measure for more than one drug of abuse in body fluids.

Target Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  • Roche Diagnostics OnTrak TesTcard 9
  
Viral  
Human Immunodeficiency Virus (HIV)  
Serum  
Genotyping
Tests that "fingerprint" HIV according to chromosomal makeup in order to track specific strains.

Target Products:

  • Roche Diagnostics AMPLICOR HIV-1 Monitor Test
  • Roche Diagnostics Amplicor HIV-1 Test
  • Roche Diagnostics COBAS Amplicor HIV-1 Test
  
Microbiology
Culture and Sensitivity  
Identification/Manual  
Reagents  
Identification Confirmation  
Bacterial  
Enterococcus/VRE
Confirmatory test for identification of suspected Enterococcus from culture isolates.

Buyer Products:

  • ID Biomedical Velogene Genomic Identification Assay for Vancomycin-Resistant Enterococci (VRE)
  
Staphylococcus/MRSA
Test kits used to identify Staphylococcus bacteria in a culture source.

Buyer Products:

  • ID Biomedical Velogene Genomic Identification Assay for MRSA
  
Genetic Probes/PCR  
Reagents  
Bacterial  
Tuberculosis
Genetic probe for detection and/or quantitation of Mycobacterium tuberculosis.

Target Products:

  • Roche Diagnostics COBAS AMPLICOR Mycobacterium Intracellular (MIN) Test/AMPLICOR MIN Test
  • Roche Diagnostics COBAS AMPLICOR MTB Test/AMPLICOR MTB Test
  • Roche Diagnostics COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
  
Viral  
Cytomegalovirus
Genetic probe for detection and/or quantitation of Cytomegalovirus.

Target Products:

  • Roche Diagnostics COBAS AMPLICOR CMV Monitor Test
  • Roche Diagnostics AMPLICOR CMV Test
  
Hepatitis B Virus
Genetic probes for detection and/or quantitation of HBV.

Target Products:

  • Roche Diagnostics COBAS AmpliScreen HBV Test
  • Roche Diagnostics AMPLINAT MPX Test
  
Hepatitis C Virus
Genetic probes for detection and/or quantitation of HCV.

Target Products:

  • Roche Diagnostics COBAS AmpliScreen HCV Test
  • Roche Diagnostics AMPLINAT MPX Test
  • Roche Diagnostics COBAS AMPLICOR HCV Test/AMPLICOR HCV Test
  • Roche Diagnostics COBAS AMPLICOR HCV Monitor Test/AMPLICOR HCV Monitor Test
  
Human Immunodeficiency Virus (HIV)
Genetic probes for detection and quantification of HIV.

Target Products:

  • Roche Diagnostics COBAS AmpliScreen HIV-1 Test
  • Roche Diagnostics AMPLINAT MPX Test
  • Roche Diagnostics Amplicor HIV-1 Test
  
Human Papilloma Virus
Genetic probes for the detection of HPV.

Target Products:

  • Amplicor HPV Test
  • Linear Array HPV Genotyping Test
  • Roche Diagnostics Digene Hybrid Capture II HPV Test
  
West Nile Virus
Genetic probe for detection and/or quantitation of West Nile Virus.

Target Products:

  • Roche Diagnostic TaqScreen West Nile Virus Test
  
Specimen Collection  
Blood  
Capillary  
Lancets
Sharps type of device used to puncture the skin in order to collect a capillary blood sample.

Target Products:

  • Roche Diagnostics Safe-T-Pro Lancets
  • Roche Diagnostics Softclix Pro Lancets
  • Roche Diagnostics SoftTouch Lancets
  • Roche Diagnostics Accu-Chek Autoclix Lancing System
  
Urinalysis  
Analyzers  
Chemistry
Analyzers used to perform chemical analysis of urine.

Target Products:

  • Roche Diagnostics Urisys 2400
  • Roche Diagnostics Miditron M
  • Roche Diagnostics Miditron Junior II
  • Roche Diagnostics Urisys 1100
  
Reagents  
Test Strips
Reagents, in a embedded strip format, used to perform chemical, and physical analysis of urine or body fluids.

Target Products:

  • Roche Diagnostics Chemstrip Series
  
Drug Delivery  
Pulmonary Delivery  
Aerosol Therapy  
Metered Dose  
Dry Powder  
Inhalers (DPI)
Mouthpiece-type of medical devices from which the patients inhale the medication mixture

Buyer Products:

  • Diskus/Accuhaler
  
Liquid  
Breath Actuated (BAI)
Inhalation devices which are activated by the patients' inspiration

Buyer Products:

  • Surehaler
  
Manual
Inhalation devices which are activated by the patient's manual control

Buyer Products:

  • MDI Dose Counter
  
Respiratory  
Treatment  
Nasal Expanders
Device designed to expand the nasal passages.

Buyer Products:

  • Breathe Right Vapor Shot Portable Vaporizer
  • Children's Breathe Right Nasal Strip
  • Breathe Right Mentholated Nasal Strip
  • Breathe Right Nasal Strip
  • Children's Breathe Right Mentholated Nasal Strip
  • Breathe Right Vapor Strip
  
Nutritional Health  
Dietary/Naturopathic Supplements  
General Health
Products consisting of dietary/naturopathic supplements that are intended to support general health.

Buyer Products:

  • GlaxoSmithKline plc
  
Women`s Health
Products consisting of dietary/naturopathic supplements that are intended to support women's health.

Buyer Products:

  • GlaxoSmithKline plc
  
Outsourced Services  
Development/Manufacturing Services  
Contract Manufacturing Organizations (CMO)  
Pharmaceuticals  
Biologics
Active Ingredient Contract Manufacturing Organizations (CMO) that manufacture antibodies, proteins, and genetic materials.

Buyer Products:

  • Manufacturing Services
  
Scientific Products  
Analytical Instruments  
Analyzers  
Gas Monitors  
Multiple Component  
Benchtop
Multi-component gas monitors that are generally located on the counter top.

Target Products:

  • Roche Diagnostics AVL OMNI 1-9
  
Bioanalytical Instruments  
Biomolecular  
Microplate Readers  
Systems  
Multiple Parameter
Microplate reader systems that used a combination of fluorescent, luminescent, and/or photoemission detectors.

Target Products:

  • Roche Diagnostics Lumi-Imager
  
Sequencers  
Automated  
Nucleic Acid
Automated gel electrophoresis or capillary electrophoresis sequencers used to analyze nucleic acid sample.

Target Products:

  • Genome Sequencer 20
  
Synthesizers  
Peptides
Synthesizer systems used for the identification and synthesis of peptide samples.

Target Products:

  • Roche Diagnostics Rapid Translation System
  
Thermal Cyclers  
Accessories
Supplementary products used to enhance the performance of a thermal cycler.

Target Products:

  • Roche Diagnostics MagNA Pure LC
  
Systems
Thermal cycler components assembled as a single unit.

Target Products:

  • Roche Diagnostics LightCycler
  
Consumables  
Bioanalytical Chemistry  
Molecular Biology  
Microarray Technology  
Microarray Chips
Microarray/biochip components that give detailed analysis of differential expression in normal and diseased or treated cells.

Target Products:

  • Roche Diagnostics AmpliChip CYP 450
  
Nucleic Acid Analysis  
Kits  
Nucleic Acid  
Transfection
Nucleic acid analysis kits that are used for the introduction of DNA into a recipient eukaryote cell and its subsequent integration into the recipient cells chromosomal DNA

Target Products:

  • Roche Diagnostics FuGENE
  
General Laboratory Equipment  
Automation Equipment  
Robotic Instruments  
Workstations
Robotic instrument systems that transfer liquid and gas samples and also heat and cool samples.

Target Products:

  • Roche Diagnostics Task Targeted Automation
  

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Pfizer Inc. n/a 192,581.140 10.35 12.73 3.92 4.03 6.86
Johnson & Johnson n/a 183,699.702 17.80 15.53 3.32 3.00 15.70
Novartis AG (ADR) n/a 132,695.720 24.32 16.91 3.48 3.56 3.28
sanofi-aventis (ADR) n/a 128,575.316 23.50 13.13 3.19 3.26 n/a
Merck & Co., Inc. n/a 115,407.282 24.99 18.03 5.02 4.92 7.14
Abbott Laboratories n/a 91,543.593 59.09 20.96 4.05 4.04 n/a
AstraZeneca plc (ADR) n/a 81,935.278 13.26 13.57 3.01 2.92 8.66
Wyeth n/a 75,840.119 17.51 16.02 3.63 3.44 7.06
Eli Lilly & Co. n/a 67,328.131 28.81 17.46 4.16 3.79 7.38
Amgen, Inc. n/a 62,667.219 20.48 13.09 4.25 4.15 13.05
Bristol Myers Squibb Co. n/a 59,927.581 38.39 21.43 3.38 3.05 16.40
Bayer AG (ADR) n/a 52,907.745 10.05 16.01 1.28 1.16 n/a
Gilead Sciences, Inc. n/a 38,763.422 n/a 27.28 11.53 9.44 17.22
Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50
MedImmune, Inc. n/a 13,568.208 83.92 64.91 10.02 9.34 10.65
Shire plc (ADR) n/a 12,878.614 39.05 36.38 6.73 5.78 6.63
Amylin Pharmaceuticals, Inc. n/a 5,590.854 n/a -29.49 9.31 6.86 9.13
Vertex Pharmaceuticals Incorporated n/a 4,120.926 n/a -11.29 16.75 13.75 8.22
ImClone Systems Incorporated n/a 3,381.639 19.91 32.11 5.89 5.67 4.21
OSI Pharmaceuticals, Inc. n/a 2,134.020 n/a 30.67 6.34 6.54 n/a
Inverness Medical Innovations, Inc. n/a 1,851.748 n/a 32.29 3.08 2.84 6.71
Buyer
  HSBC Holdings plc (ADR) n/a 215,769.301 13.26 12.13 2.84 3.04 3.04
The Procter & Gamble Company n/a 199,893.680 20.37 20.85 2.66 2.62 n/a
Target
  Pfizer Inc. n/a 192,581.140 10.35 12.73 3.92 4.03 6.86
Johnson & Johnson n/a 183,699.702 17.80 15.53 3.32 3.00 15.70

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50
Beckman Coulter, Inc. n/a 4,146.577 21.66 20.78 1.61 1.50 25.88
PDL BioPharma Inc. n/a 3,073.671 n/a 78.88 7.12 6.33 25.74
Crucell N.V. (ADR) n/a 1,439.842 n/a -35.60 13.83 4.75 3.70
Genelabs Technologies n/a 54.864 n/a n/a 4.89 n/a 18.25
Buyer
  Encysive Pharmaceuticals, Inc. 92.10% 208.665 n/a -2.12 10.99 4.95 n/a
Cytokinetics, Inc. 87.00% 316.451 n/a -4.23 64.45 25.13 2.59
Target
  Aspreva Pharmaceuticals Corporation 100.00% 707.107 6.11 5.49 3.35 2.86 2.20
Pharmasset, Inc. 39.30% 189.386 n/a n/a 41.60 n/a 6.68
Emisphere Technologies, Inc. 20.60% 87.484 n/a -2.39 12.05 7.98 n/a
deCODE genetics, Inc. 17.00% 210.402 n/a -2.28 5.40 4.90 n/a
PDL BioPharma Inc. 3.30% 3,073.671 n/a 78.88 7.12 6.33 25.74
sanofi-aventis (ADR) n/a 128,575.316 23.50 13.13 3.19 3.26 n/a
Genentech, Inc. n/a 81,388.978 33.94 29.34 8.03 6.96 9.71
Adobe Systems Incorporated n/a 25,631.191 47.06 31.42 9.98 8.33 10.21
Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50
Merck Serono S.A. (ADR) n/a 13,917.045 18.92 n/a 4.96 n/a 4.14
Beckman Coulter, Inc. n/a 4,146.577 21.66 20.78 1.61 1.50 25.88
Atmel Corporation n/a 2,789.347 141.02 23.21 1.65 1.66 2.84
Sanmina-SCI Corporation n/a 1,907.586 n/a 27.38 0.18 0.17 2.96
Affymetrix, Inc. n/a 1,689.834 n/a 86.46 4.84 4.48 4.41
Valeant Pharmaceuticals International n/a 1,467.170 n/a 21.51 1.59 1.60 n/a
Crucell N.V. (ADR) n/a 1,439.842 n/a -35.60 13.83 4.75 3.70
Open Text Corporation (USA) n/a 1,140.281 53.70 17.97 2.17 1.93 n/a
Esterline Technologies Corporation n/a 1,105.322 18.41 17.04 1.08 0.98 9.07

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Wal-Mart Stores, Inc. n/a 194,831.254 16.95 14.81 0.55 0.51 4.30
CVS Caremark Corporation n/a 60,156.441 41.94 20.03 1.28 0.78 27.43
Target Corporation n/a 49,736.933 17.85 16.07 0.84 0.76 3.18
Walgreen Company n/a 45,622.784 23.22 21.90 0.89 0.84 4.32
Sears Holdings Corporation n/a 27,661.371 18.56 17.45 0.52 0.53 3.65
Costco Wholesale Corporation n/a 25,195.272 23.38 21.71 0.40 0.38 2.87
Medco Health Solutions Inc. n/a 21,677.109 25.20 22.15 0.50 0.47 n/a
The Kroger Co. n/a 21,015.343 18.83 17.93 0.32 0.31 7.70
Safeway Inc. n/a 15,407.423 17.08 17.71 0.38 0.37 4.26
Shire plc (ADR) n/a 12,878.614 39.05 36.38 6.73 5.78 6.63
Henry Schein, Inc. n/a 4,654.954 24.37 20.55 0.87 0.78 8.25
Biovail Corporation (USA) n/a 3,938.500 16.88 13.59 3.59 4.66 7.05
Rite Aid Corporation n/a 3,440.430 n/a -78.13 0.20 0.14 4.15
United Therapeutics Corporation n/a 1,397.836 20.29 43.89 8.39 7.79 9.20
ViroPharma Incorporated n/a 1,028.742 12.77 13.89 5.51 5.05 3.53
99 Cents Only Stores n/a 1,023.947 162.19 47.32 1.26 0.76 2.01
Target
  Applied Biosystem Inc. n/a 5,402.398 32.09 20.42 2.62 2.53 4.15
Gen-Probe Incorporated n/a 2,742.878 41.09 36.12 7.42 6.89 5.44
IDEXX Laboratories, Inc. n/a 2,715.145 28.16 28.30 3.47 3.01 14.70
Grupo Casa Saba, S.A. (ADR) n/a 902.426 12.71 n/a 0.43 n/a 2.04
Aspreva Pharmaceuticals Corporation n/a 707.107 6.11 5.49 3.35 2.86 2.20
Abaxis, Inc. n/a 434.240 43.11 30.31 5.04 3.94 4.97
IRIS International, Inc. n/a 245.093 n/a 32.10 3.48 2.97 4.20
Trimeris, Inc. n/a 158.294 21.43 10.54 4.28 3.44 3.55
Allion Healthcare, Inc. n/a 79.560 24.93 22.05 0.38 0.32 2.74

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Bayer AG (ADR) n/a 52,907.745 10.05 16.01 1.28 1.16 n/a
Gilead Sciences, Inc. n/a 38,763.422 n/a 27.28 11.53 9.44 17.22
Allergan, Inc. n/a 18,658.423 51.66 28.32 5.61 5.06 303.88
Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50
Gen-Probe Incorporated n/a 2,742.878 41.09 36.12 7.42 6.89 5.44
MGi Pharma, Inc. n/a 1,718.345 n/a 83.88 4.94 4.40 n/a
Crucell N.V. (ADR) n/a 1,439.842 n/a -35.60 13.83 4.75 3.70
ISIS Pharmaceuticals, Inc. n/a 820.482 n/a -15.95 33.44 25.04 43.16
SkyePharma PLC (ADR) n/a 403.419 n/a -15.47 4.00 3.19 n/a
Maxygen, Inc. n/a 341.970 n/a -5.71 13.67 19.48 1.95
Pharmacopeia Drug Discovery, Inc. n/a 120.596 n/a -3.86 7.12 5.33 3.96
Genelabs Technologies n/a 54.864 n/a n/a 4.89 n/a 18.25
Valentis, Inc. n/a 2.048 n/a n/a 3.45 n/a 3.81
Buyer
  Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
AstraZeneca plc (ADR) n/a 81,935.278 13.26 13.57 3.01 2.92 8.66
Target
  GlaxoSmithKline plc (ADR) n/a 165,197.578 15.49 14.52 3.64 3.54 15.82
Novartis AG (ADR) n/a 132,695.720 24.32 16.91 3.48 3.56 3.28
sanofi-aventis (ADR) n/a 128,575.316 23.50 13.13 3.19 3.26 n/a
Genentech, Inc. n/a 81,388.978 33.94 29.34 8.03 6.96 9.71
Amgen, Inc. n/a 62,667.219 20.48 13.09 4.25 4.15 13.05
Bayer AG (ADR) n/a 52,907.745 10.05 16.01 1.28 1.16 n/a
Gilead Sciences, Inc. n/a 38,763.422 n/a 27.28 11.53 9.44 17.22
Becton, Dickinson and Co. n/a 19,057.437 24.89 20.49 3.18 3.01 5.69
Allergan, Inc. n/a 18,658.423 51.66 28.32 5.61 5.06 303.88
Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 45,433.7 34,888.8 80,322.5
Other Revenue 0.0 0.0 0.0
Total Revenue 45,433.7 34,888.8 80,322.5
Cost of Revenue 10,092.4 8,810.0 18,902.4
SG&A Expense 14,036.6 11,118.7 25,155.2
Depreciation & Amortization 0.0 974.3 974.3
Research & Development 6,774.4 5,468.0 12,242.4
Interest Expense 0.0 0.0 0.0
Other Operating Expense -874.9 -1,216.6 -2,091.5
Total Expenses 30,028.4 25,154.4 55,182.8
Operating Income 15,405.3 9,734.4 25,139.7
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng -55.3 370.1 314.8
Other, Net 0.0 269.7 269.7
Income Before Taxes 15,350.0 10,445.6 25,795.6
Income Taxes 4,485.3 2,851.5 7,336.8
Income After Taxes 10,864.7 7,594.2 18,458.9
Minority Interest (IS) -197.5 -1,071.4 -1,268.9
Net Income - Excl. Xord. Items 10,667.2 6,522.8 17,190.0
Discontinued Operations 0.0 16.6 16.6
Net Income - Incl. Xord. Items 10,667.2 6,539.4 17,206.6
Income Avail. to Common 10,667.2 6,539.4 17,206.6
Share Items
Basic Avg. Shares Outstanding 2,799.5 1,706.0 4,505.5
Basic EPS - Excl. Xord. Items 3.81 3.82 3.82
Basic EPS - Incl. Xord. Items 3.81 3.83 3.82
Full Dilution Adjustment 0.0 0.0 0.0
Fully Diluted Shares Outstanding 2,831.0 1,728.0 4,559.0
F.D. EPS - Excl. Xord. Items 3.77 3.77 3.77
F.D. EPS - Incl. Xord. Items 3.77 3.78 3.77
Dividends Per Common Share 1.94 1.41 3.35
Balance Sheet
Assets
Cash and Equivalents 3,912.5 2,663.9 6,576.4
ST Investments 1,992.8 17,527.8 19,520.6
Accounts Receivable 10,479.5 7,435.7 17,915.2
Inventory 5,044.2 4,640.7 9,684.9
Other Current Assets 13.8 1,669.7 1,683.5
Current Assets 21,443.0 33,937.8 55,380.7
Accum D&A 0.0 0.0 0.0
PPE, Net 13,926.0 13,624.1 27,550.0
Goodwill & Intangibles 9,180.0 9,446.5 18,626.4
Long Term Investments 1,749.9 1,791.7 3,541.6
Other Assets 0.0 0.0 0.0
Other LT Assets 5,794.8 2,954.4 8,749.1
Total Assets 52,093.5 61,754.4 113,847.9
Liabilities
Accounts Payable 9,051.6 1,836.5 10,888.1
Payable/Accrued 0.0 0.0 0.0
Accrued Expenses 0.0 4,684.6 4,684.6
ST Debt 2,379.9 0.0 2,379.9
Curr Port of LTD & Cap Lease Oblg 0.0 1,696.3 1,696.3
Other (Current) Liabilities 3,266.7 2,315.4 5,582.1
Current Liab. 14,698.2 10,532.8 25,231.0
LT Debt 9,452.5 5,144.4 14,596.9
Total LT Debt 9,452.5 5,144.4 14,596.9
Minority Interest (BS) 448.3 6,116.2 6,564.5
Deferred Taxes 1,459.6 1,917.0 3,376.6
Other LT Liab. 6,412.9 5,310.4 11,723.3
Total Liabilities 32,471.6 29,020.7 61,492.3
Shareholders Equity
Common Stock 2,968.5 132.8 3,101.3
Additional Paid in Capital 2,107.4 0.0 2,107.4
Retained Earnings 14,546.1 34,345.2 48,891.4
Treasure Stock 0.0 -1,744.4 -1,744.4
Other Equity 0.0 0.0 0.0
Total Equity 19,622.0 32,733.6 52,355.6
Total Liab. & Equity 52,093.5 61,754.4 113,847.9
Shares Outstanding 2,790.0 1,725.1 4,515.1
Cash Flow
Operating Cash Flow
CF Net Income 10,864.7 0.0 10,864.7
CF Depreciation 0.0 0.0 0.0
CF Deferred Taxes 0.0 0.0 0.0
Other Non-Cash Items 6,705.2 -660.6 6,044.7
Change in Working Capital -9,422.9 9,232.4 -190.5
Total Cash From Operating Activities 8,147.0 8,571.8 16,718.8
Investing Cash Flow (not calculated)
Capital Expenditures -4,011.3 -3,447.3 -7,458.6
Other Investing Cash Flows -606.3 -2,735.3 -3,341.6
Total Cash From Investing Activities -4,617.6 -6,182.6 -10,800.2
Financing Cash Flow (not calculated)
Dividends Paid -5,334.6 -1,873.0 -7,207.6
Purchase Or Sale of Stock -2,336.5 98.8 -2,237.7
Purchase and Retirement of Debt -4.0 -363.5 -367.4
Other Financing Cash Flow -914.4 -294.6 -1,209.0
Total Cash From Financing Activities -8,589.4 -3,083.0 -11,672.4
Exchange Rate Effects -479.9 -151.0 -631.0
Net Change in Cash -5,540.0 -844.8 -6,384.8
Cash Taxes Paid 7,548.6 2,321.2 9,869.7
Cash Interest Paid 691.3 284.6 975.9