Summary

Other Scenarios:

Buyer: GlaxoSmithKline PLC (GSK) Last Price: 44.18 Market Cap.: 112.21B
Target: Teva Pharmaceutical Industries Ltd (TEVA) Last Price: 38.90 Market Cap.: 36.58B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
Consumer   890
Consumer Products and Services   341
Healthcare 732
Biopharmaceuticals 334
Medical Devices 177
Nutritional Health   26
Outsourced Biomedical Services 39
Scientific Products   23
Veterinary Products and Services   8

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business

Buyer (Total: 334)
  • GSK835726 (Oral Histamine H1/H3 Dual Antagnoist)
  • GSK1004723 (Intranasal Histamine H1/H3 Dual Antagonist)
  • 256066 (PDE 4 Inhibitor)
  • Contac 12 Hour Allergy (Clemastine Fumarate)
Target (Total: 449)
  • Promethazine Hydrochloride
  • Hydroxyzine Pamoate
  • Cyproheptadine HCl
  • Ipratropium
Buyer
  • Sensodyne
  • Polygrip/Super Poligrip
  • Targon
  • Aquafresh
Target
  • Adenosine Injection
  • ratiopharm - Merckle Biotec GmbH
  • TEVA API Services
  • Taiyo Pharmaceutical Industry Co. Ltd.

Business Relationship Summary:

Top Key Suppliers

Top Key Customers

Buyer (Total: 68)
  • Celldex Therapeutics Inc (CLDX)
  • Anacor Pharmaceuticals Inc (ANAC)
  • Flamel Technologie SA (FLML)
  • Avanir Pharmaceuticals Inc (AVNR)
Target (Total: 28)
  • Antares Pharma Inc (AIS)
  • 3M Co (MMM)
  • Astrazeneca PLC (AZN)
  • Shire PLC (SHPGY)
Buyer (Total: 17)
  • Roche Holding AG (RHHBY)
  • Eli Lilly & Co (LLY)
  • Celgene Corp (CELG)
  • Allergan Inc (AGN)
Target (Total: 6)
  • Watson Pharmaceuticals Inc (WPI)
  • Par Pharmaceutical Cos Inc (PRX)
  • Medicines Co (MDCO)
  • Paladin Labs Inc (PLDLF)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 96,461 42,000
Revenue Per Employee 457,425.3 425,978.0
Total Revenue 6,640.0 5,102.0
Total Expenses 4,603.0 4,174.0
Other Revenue n/a n/a
Cost of Revenue 1,790.0 2,493.0
SG&A Expense 2,071.0 1,228.0
Research & Development 892.0 292.0
Other Operating Expense -308.0 n/a
Operating Income 2,037.0 928.0
Unusual Income 133.0 149.0
LT Debt to Capital 57.74 30.59
Fwd P/E 11.28 6.95
Fwd P/Rev 2.50 1.71
Book Value 8,776.0 23,051.0
Curr Portion of LTD/Cap Lease n/a 531.0

Individual Company Summary

Focused

Buyer

Focused (): Healthcare > Biopharmaceuticals

Target

Focused (): Healthcare > Biopharmaceuticals

Business Description

Buyer

GlaxoSmithKline plc (GSK) is global healthcare group, which is engaged in the creation and discovery, development, manufacture and marketing of pharmaceutical products, including vaccines, over-the-counter (OTC) medicines and health-related consumer products. Its principal pharmaceutical products include medicines in the therapeutic areas, such as respiratory, anti-virals, central nervous system, cardiovascular and urogenital, metabolic, anti-bacterials, oncology and emesis, dermatalogicals and vaccines. The Company's segments include Pharmaceuticals and Consumer Healthcare. On July 22, 2009, it acquired Stiefel Laboratories, Inc. On October 30, 2009, it acquired Pfizer Inc.?s HIV business and combined it with its own HIV business to form ViiV Healthcare Limited. On November 10, 2009, it acquired the Algerian pharmaceutical, manufacturing and distribution group, Laboratoire Pharmaceutique Algerien. On December 18, 2009, it acquired NovaMin Technology Inc.

Target

Teva Pharmaceutical Industries Limited (Teva) is a global pharmaceutical and drug company. It develops, produces and markets generic drugs in all treatment categories. The Company has a pharmaceutical business, whose principal products include Copaxone and Azilect. Teva?s active pharmaceutical ingredient (API) business provides vertical integration to Teva?s own pharmaceutical production. manufactures and sells generic pharmaceutical products in a range of dosage forms, including tablets, capsules, ointments, creams, liquids, injectables and inhalants. As December 31, 2010, it had direct operations in approximately 60 countries, including 40 finished dosage pharmaceutical manufacturing sites in 19 countries, 28 pharmaceutical research and development (R&D) centers and 21 API manufacturing sites. During the year ended December 31, 2010, it acquired Laboratoire Theramex, Corporacion Infarmasa (Infarmasa) and Merckle ratiopharm Group (ratiopharm).

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 73.6 51.39
Operating Margin % 28.18 16.4
Quick Ratio 0.8 0.53
Current Ratio 1.12 1.1
Coverage Ratio n/a n/a
Total Assets 40,802.0 50,470.0
Return on Equity % 273.46 50.6
Return on Assets % 58.82 23.11
Cash+ ST Inv. Per Share 1.16 1.25
Total Debt 14,715.0 14,522.0
Total Debt to Equity % 167.67 63
Total Debt to Tangible Equity % n/a n/a
Debt to Asset % 36.06 28.77

Product Summary

Sector Buyer Target
Consumer  
Consumer Products and Services  
Personal Care and Cleaning Products
Companies engaged in the manufacturing of personal care products, such as cosmetics, fragrances, skin lotion, sanitary/personal care paper (tissues), shampoo and other toiletries; and household cleaning products, such as window/surface cleaner, and table polish.
 
Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.

Buyer Products:

  • 681323 (p38 Kinase Inhibitor)
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes therapeutics that treat female genital disorders, pregnancy, and childbirth.
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
 
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes therapeutics that treat and manage weight disorders.
Wound Management
The Wound Management Subsector includes therapeutics that treat cuts, abrasions, and burns from trauma or diseases.
 
Medical Devices
Clinical Diagnostics
The Clinical Diagnostics Subsector includes medical devices that analyze human body specimens within a medical setting. These devices, including equipment, biological and chemical reagents are primarily used for the diagnosis of diseases.
 
Drug Delivery
The Drug Delivery Subsector includes medical devices that facilitate the delivery of medications through different anatomical entryways, including blood vessels, skin, the mouth, and the lungs. Common devices in this sector include vascular access catheters, needles, implants, and inhalers.
 
Radiology
The Radiology Subsector includes medical devices that generate images of internal physiology.
 
Respiratory
The Respiratory Subsector includes medical devices that diagnose and treat respiratory diseases.
 
Nutritional Health  
Dietary/Naturopathic Supplements
The Dietary/Naturopathic Subsector includes nutritional biochemicals and nutrients derived from natural sources that are intended to support health.
 
Outsourced Biomedical Services
Development/Manufacturing Services
The Development/Manufacturing Services Subsector includes companies that provide research, development, manufacturing, sales and marketing to biopharmaceutical and medical device companies.
Drug Delivery Technology
The Drug Delivery Technology Subsector includes companies that develop novel delivery methods for therapeutics.
 
Scientific Products  
Bioanalytical Instruments
The Bioanalytical Subsector includes scientific products, devices, apparatuses, and consumables used to determine the quantitative and qualitative nature of a biological samples.
 
Veterinary Products and Services  
Veterinary Pharmaceuticals
The Veterinary Pharmaceuticals Subsector includes companies that manufacture veterinary pharmaceuticals and vaccines for the prevention and treatment of veterinary diseases.

Target Products:

  • IVX Animal Health, Inc.
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
Consumer  
Consumer Products and Services  
Personal Care and Cleaning Products  
Oral Care
Oral Care products, including Toothpaste, Mouthwash, and denture adhesive.

Buyer Products:

  • Sensodyne
  • Polygrip/Super Poligrip
  • Targon
  • Aquafresh
  • Biotene
  • Polident
 
Sanitary/Personal Care Paper
Companies engaged in the manufacturing of sanitary/personal care paper (tissues).

Buyer Products:

  • Massengill
 
Skin Care
Companies engaged in the manufacturing of skin care products, such as suntan lotion, skin lotion, sanitizer, shaving cream, and moisturizer. Also includes manufacturers of non-electrical shaving equipment.

Buyer Products:

  • Chap-et
 
Healthcare
Biopharmaceuticals
Allergies
Dermatology  
Antihistamines
Products that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Promethazine Hydrochloride
  • Hydroxyzine Pamoate
 
Antihistamines/Antiserotonins
Therapeutics that inhibit the inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Cyproheptadine HCl
 
Ophthalmology  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Promethazine Hydrochloride
 
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Cyproheptadine HCl
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for treatment of allergic reactions in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK835726 (Oral Histamine H1/H3 Dual Antagnoist)
  • GSK1004723 (Intranasal Histamine H1/H3 Dual Antagonist)
  • 256066 (PDE 4 Inhibitor)
 
Systemic  
Anaphylactic Shock  
Adjunctive Treatments  
Antihistamines/Antiserotonins
Therapeutics that assist the primary treatment of a life-threatening systemic allergic reaction resulting from secondary or subsequent exposure to a foreign substance by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Cyproheptadine HCl
 
Upper Respiratory
Anticholinergic Agents
Therapeutics that treat allergic reactions by inhibiting the action of acetylcholine on post-ganglionic nerves as well as smooth muscle.

Target Products:

  • Ipratropium
 
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Contac 12 Hour Allergy (Clemastine Fumarate)

Target Products:

  • Fexofenadine Hydrochloride
  • Cetirizine Hydrochloride
  • Promethazine Hydrochloride
  • Genahist (Diphenhydramine HCl)
  • Clemastine Fumarate
  • Diphenhydramine HCl
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Cyproheptadine HCl
 
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and relieve or prevent coughs.

Target Products:

  • Cetirizine Hydrochloride/Pseudoephedrine HCl Extended Release Tablets
  • Genac (Triprolidine/Pseudoephedrine HCl)
 
Antihistamines/Decongestants/Analgesics/Antipyretics
Therapeutics that treat allergic reactions by suppressing inflammation, reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Day And Night Allegry/Sinus Relief (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
  • Contac Allergy/Sinus Night Capsules (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
 
Antihistamines/Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat allergic reactions by suppressing inflammation, reducing mucous build up, relieving or preventing coughs, relieving pain, and reducing fever.

Buyer Products:

  • Contac Severe Cold Formula Night Strength (Doxylamine Succinate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen/Alcohol)
  • Contac Severe Cold Formula Capsules (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Severe Cold & Flu Hot Medicine (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation using a steroidal compound.

Buyer Products:

  • Flonase (Fluticasone Propionate Nasal Spray)
  • Veramyst (Intranasal Fluticasone Furoate)/Formely Allermist
  • Beconase AQ (Beclomethasone Dipropionate, Monohydrate)

Target Products:

  • Triamcinolone Acetonide Nasal Spray
  • QNASL (Beclomethasone Dipropionate)
  • Nasacort AQ Nasal Spray (Triamcinolone Acetonide)
Cardiovascular System
Heart Disorders
Acute Coronary Syndrome (ACS)  
Factor Xa Inhibitors
Therapeutics that treat acute coronary syndrome by due to platelets and cell matter by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
 
Angina  
Anticoagulating Agents  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Target Products:

  • Bivalirudin
  • Enoxaparin Sodium
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat chest pains by inhibiting stimulation of beta adrenergic receptors of the heart muscle.

Target Products:

  • Nadolol
  • Metoprolol Tartrate
  • Atenolol
 
Calcium Channel Blocking Agents
Therapeutics that treat chest pains by preventing the entry of calcium into heart muscle cells.

Target Products:

  • Verapamil HCl
  • Nifedical XL (Nifedipine)
  • Diltiazem HCl Extended-Release Capsules
  • Diltiazem HCl
  • Amlodipine Besylate
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that reduce the risk of chest pains by preventing the synthesis of cholesterol.

Target Products:

  • Rosuvastatin
 
Vasodilatory Agents
Therapeutics that treat chest pains by acting on blood vessels to lower blood pressure.

Target Products:

  • Isosorbide Mononitrate
 
Arrhythmia
Adenosine A1 Receptor Agonists
Therapeutics that treat abnormal rhythm of the heart beat by selectively stimulating the A1 adenosine receptor, slowing the speed of AV nodal conduction

Target Products:

  • Adenosine
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat abnormal rhythm of the heart beat by inhibiting the stimulation of beta adrenergic receptors of the heart muscle.

Target Products:

  • Sotalol Hydrochloride
 
Calcium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of calcium into heart muscle cells.

Target Products:

  • Verapamil HCl
 
Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of potassium into heart muscle cells.

Target Products:

  • Quinidine Sulfate
 
Sodium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium into heart muscle cells.

Buyer Products:

  • Reliant Pharmaceuticals - Rhythmol SR (Propafenone Hydrochloride Extended Release)

Target Products:

  • Mexiletine
  • Disopyramide Phosphate
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium and potassium into heart muscle cells.

Buyer Products:

  • Lanoxin (Digoxin)

Target Products:

  • Amiodarone Hydrochloride
Heart Failure (HF)
Adjunctive Treatments  
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that assist in the primary treatment of the ineffective pumping of the heart by inhibiting the renin-angiotensin system.

Target Products:

  • Quinapril Hydrochloride
  • Fosinopril Sodium
  • Lisinopril
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat the ineffective pumping of the heart by inhibiting the renin-angiotensin system.

Target Products:

  • Ramipril
  • Trandolapril
  • Captopril
  • Enalapril
 
Angiotensin II Receptor Antagonists
Therapeutics that treat congestive heart failure by blocking the angiotensin II receptor.

Target Products:

  • Valsartan
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat the ineffective pumping of the heart by blocking beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Coreg (Carvedilol)
  • Coreg CR (Carvedilol Controlled Release)

Target Products:

  • Carvedilol
Complications
Edema
Loop Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Furosemide
  • Bumetanide
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Dyazide (Triamterene/Hydrochlorothiazide)

Target Products:

  • Triamterene and Hydrochlorothiazide
Sulfonamide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Indapamide
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Hydrochlorothiazide
  • Metolazone
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the ineffective pumping of the heart by preventing the synthesis of cholesterol.

Target Products:

  • Rosuvastatin
 
Recombinant B-Type Natriuretic Peptides (BNP)
Therapeutics that treat the ineffective pumping of the heart by increasing the excretion of sodium and water in urine.

Buyer Products:

  • Natrecor (Nesiritide Citrate)
 
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat the ineffective pumping of the heart by preventing the entry of sodium or potassium into heart muscle cells.

Buyer Products:

  • Lanoxin (Digoxin)
 
Vasodilatory Agents
Therapeutics that treat the ineffective pumping of the heart by acting on blood vessels to lower blood pressure.

Target Products:

  • Sodium Nitroprusside
 
Myocardial Infarction (MI)
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat irreversible damage to the heart muscle by inhibiting the renin-angiotensin system.

Target Products:

  • Perindopril Erbumine
  • Lisinopril
 
Angiotensin II Receptor Antagonists
Therapeutics that treat/prevent myocardial infarction by blocking the angiotensin II receptor, which results in dilated blood vessels.

Target Products:

  • Valsartan
 
Anticoagulating Agents
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Argatroban

Target Products:

  • Enoxaparin Sodium
  • Argatroban
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Coreg (Carvedilol)
  • Coreg CR (Carvedilol Controlled Release)

Target Products:

  • Carvedilol
  • Metoprolol Tartrate
  • Atenolol
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat irreversible damage to the heart muscle by preventing the synthesis of cholesterol.

Target Products:

  • Rosuvastatin
  • Pravastatin Sodium
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 681323 (p38 Kinase Inhibitor)
  • Losmapimod (p38 Kinase Inhibitor)
  • GSK1278863 (Prolyl Hydroxylase Inhibitor)
  • Rilapladib (Lp-PLA2 Inhibitor)
  • GSK2190914/AM-103 (5-Lipoxygenase Activating Protein Inhibitor)

Target Products:

  • Cephalon, Inc. - Revascor (Mesoblast Mesynchymal Precursor Cells)
  • MultiGene Angio
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in very early stages of research where no human subject is involved.

Target Products:

  • Cephalon, Inc. - Revascor (Mesoblast Mesynchymal Precursor Cells)
 
Vascular Disorders
Atherosclerosis
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the narrowing or hardening of the arteries by preventing the synthesis of cholesterol.

Target Products:

  • Rosuvastatin
  • Lovastatin
  • Pravastatin Sodium
 
Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors
Therapeutics that treat atherosclerosis by inhibiting lipoprotein-associated phospholipase A2 (Lp-PLA2), slowing the expansion of necrotic core, resulting in reduced buildup of arterial plaque.

Buyer Products:

  • Darapladib (Lp-PLA2 Inhibitor)
 
Coronary Artery Disease (CAD)  
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the narrowing or hardening of the coronary arteries of the heart muscle by preventing the synthesis of cholesterol.

Target Products:

  • Fluvastatin
  • Simvastatin
 
Deep Vein Thrombosis (DVT)
Anticoagulating Agents (Anticoagulants)
Factor Xa Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Fraxiparine (Nadroparin)
 
Thrombin Inhibitors
Therapeutics that prevent or treat clots in blood vessels by preventing blood clots from forming.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)
  • Argatroban

Target Products:

  • Enoxaparin Sodium
  • Argatroban
Hypertension
Alpha Adrenergic Receptor Agonists
Therapeutics that treat high blood pressure by stimulating the alpha adrenergic receptors of the heart muscle.

Target Products:

  • Clonidine Transdermal Patch
  • Methyldopa
  • Guanabenz Acetate
 
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that treat high blood pressure by blocking alpha adrenergic receptors of the heart muscle.

Target Products:

  • Prazosin HCl
  • Doxazosin Mesylate
 
Alpha Blockers/Beta Blockers
Therapeutics that treat high blood pressure by blocking alpha and beta adrenergic receptors of the heart muscle.

Target Products:

  • Labetalol HCl
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat high blood pressure by inhibiting the renin-angiotensin system.

Target Products:

  • Perindopril Erbumine
  • Moexipril Hydrochloride
  • Quinapril Hydrochloride
  • Trandolapril
  • Fosinopril Sodium
  • Captopril
  • Lisinopril
  • Benazepril Hydrochloride
  • Enalaprilat
  • Enalapril
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)/Calcium Channel Blockers
Therapeutics that treat high blood pressure by inhibiting the renin-angiotensin system and preventing the entry of calcium into heart muscle cells.

Target Products:

  • Benazepril Hydrochloride/Amlodipine
 
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by inhibiting the renin-angiotensin system and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Benazepril Hydrochloride/Hydrochlorothiazide
  • Enalapril Maleate/Hydrochlorothiazide
  • Captopril/Hydrochlorothiazide
  • Lisinopril/Hydrochlorothiazide
  • Moexipril Hydrochloride/Hydrochlorothiazide
  • Fosinopril Sodium/Hydrochlorothiazide
 
Angiotensin II Receptor Antagonists
Therapeutics that treat high blood pressure by blocking the angiotensin II receptor.

Target Products:

  • Losaratan Potassium
  • Valsartan
  • Irbesartan
 
Angiotensin II Receptor Antagonists/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by blocking the angiotensin II receptor and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Losartan Potassium/Hydrochlorothiazide
  • Irbesartan/Hydrochlorothiazide
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Reliant Pharmaceuticals - EUR-1000 (Long Acting Propranolol)
  • InnoPran Xl (Propranolol Hydrochloride Extended Release)
  • Coreg CR (Carvedilol Controlled Release)
  • Coreg (Carvedilol)

Target Products:

  • Carvedilol
  • Nadolol
  • Metoprolol Tartrate
  • Atenolol
  • Bisoprolol Fumarate
Beta Receptor Blocking Agents (Beta Blockers)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Bisoprolol Fumarate/Hydrochlorthiazide
 
Calcium Channel Blocking Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • DynaCirc CR (Isradipine)

Target Products:

  • Nifediac CC (Nifedipine Extended-Release)
  • Verapamil HCl
  • Nifedical XL (Nifedipine)
  • Nicardipine HCl
  • Diltiazem HCl Extended-Release Capsules
  • Amlodipine Besylate
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Atorvastatin Calcium Tablets
 
Dopamine Receptor Agonists
Therapeutics that treat high blood pressure by stimulating the dopamine receptors of the heart muscle.

Target Products:

  • Fenoldopam
 
Loop Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Furosemide
  • Torsemide
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of water and sodium, but not potassium in urine.

Buyer Products:

  • Dyazide (Triamterene/Hydrochlorothiazide)

Target Products:

  • Triamterene and Hydrochlorothiazide
Sulfonamide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Indapamide
 
Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Hydrochlorothiazide
 
Vasodilatory Agents
Therapeutics that treat high blood pressure by causing relaxation of the blood vessels.

Target Products:

  • Hydralazine HCl
  • Sodium Nitroprusside
 
Hypotension  
Alpha Adrenergic Receptor Agonists
Therapeutics that treat low blood pressure by stimulating alpha adrenergic receptors.

Target Products:

  • Norepinephrine Bitartrate
 
Peripheral Vascular Disease  
Blood Viscosity Reducing Agents
Therapeutics that treat arterial obstruction outside of the heart by altering the flow of red blood cells.

Target Products:

  • Cilostazol
  • Pentoxifylline
 
Primary Pulmonary Hypertension
Phosphodiesterase Type 5 Inhibitors (PDE-5 Inhibitors)
Therapeutics that treat hypertension by increasing level of nitric oxide that help to dilate blood vessels.

Target Products:

  • Sildenafil Citrate 20mg (Generic To Revatio)
 
Prostacyclins
Therapeutics that relieve pulmonary hypertension by causing vasodilation of the pulmonary blood vessels.

Buyer Products:

  • Flolan (Epoprostenol Sodium)

Target Products:

  • Epoprostenol Sodium
Stroke  
Angiotensin II Receptor Antagonists
Therapeutics that reduce the risk of stroke by reducing high blood pressure through blocking the angiotensin II receptor.

Target Products:

  • Losaratan Potassium
 
Angiotensin II Receptor Antagonists/Thiazide Diuretic Agents
Therapeutics that reduce the risk of stroke by blocking the angiotensin II receptor and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Losartan Potassium/Hydrochlorothiazide
 
Anticoagulating Agents (Anticoagulants)  
Platelet Aggregation Inhibitors  
Adenosine Diphosphate (ADP) Inhibitors
Therapeutics that prevent or treat damage to nerve cells of the brain by preventing platelets from clumping together.

Target Products:

  • Ticlopidine HCl
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat damage to nerve cells of the brain by preventing the synthesis of cholesterol.

Target Products:

  • Rosuvastatin
 
Thromboembolism
Anticoagulating Agents (Anticoagulants)
Platelet Aggregation Inhibitors  
Phosphodiesterase Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing platelets from clumping together.

Target Products:

  • Dipyridamole
 
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)

Target Products:

  • Enoxaparin Sodium
Dermatology
Acne
Vulgaris
Antibacterial Agents
Lincosamides
Therapeutics that treat acne vulgaris caused by bacterial infection by inhibiting bacterial protein synthesis.

Buyer Products:

  • Duac Low Dose (Clindamycin/Benzolyl Peroxide Gel)
 
Tetracyclines
Therapeutics that treat acne caused by bacterial infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Target Products:

  • Tetracycline HCl
  • Minocycline HCl
 
Antibacterial Agents/Retinoids
Therapeutics that treat acne by preventing bacterial growth and helping in cell differentiation.

Buyer Products:

  • Veltin
 
Keratolytic Agents
Therapeutics that soften, separate, and cause the shedding of skin.

Buyer Products:

  • Duac Low Dose (Clindamycin/Benzolyl Peroxide Gel)
 
Retinoids/Vitamin A Analogs
Therapeutics that treat acne by helping in cell differentiation as well as prevent cell proliferation.

Buyer Products:

  • Stiefel Fabior (Tazarotene Foam)

Target Products:

  • Adapalene Gel
Hair Disorders  
Alopecia (Hair Loss)  
5 Alpha Reductase Inhibitors
Therapeutics that treat hair loss by blocking the action of an enzyme that converts testosterone to a testosterone derivative.

Target Products:

  • Finasteride
 
Vasodilatory Agents
Therapeutics that treat hair loss by dilating blood vessels.

Target Products:

  • Minoxidil Top 5% Men Solution
 
Lesion/Scaling Disorders
Chronic Urticaria  
Antihistamines
Therapeutics that treat allergic skin conditions by blocking the action of histamines.

Target Products:

  • Fexofenadine Hydrochloride
  • Cetirizine Hydrochloride
 
Dermatitis
Atopic (Eczema)
Immunomodulators
Therapeutics that treat atopic dermatitis by inhibiting T-lymphocyte activation.

Buyer Products:

  • Protopic (Tacrolimus)
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat atopic dermatoses by inhibiting the accumulation of inflammatory cells like leucocytes and macrophages at the inflammation site.

Target Products:

  • Triamcinolone Acetonide
 
Seborrheic (Dandruff)
Antifungal Agents  
Imidazoles
Therapeutics that treat and prevent skin diseases caused by fungi.

Target Products:

  • Ciclopirox Topical Solution
 
Coal Tar
A coal byproducts used in the treatment of various skin disorders.

Buyer Products:

  • Tegrin Dandruff Shampoo (Coal Tar)
 
Dermatoses  
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation by inhibiting the accumulation of inflammatory cells like leucocytes and macrophages at the inflammation site.

Target Products:

  • Triamcinolone Acetonide
  • Fluocinonide
  • Clobetasol Propionate
  • Betamethasone Dipropionate
 
Diaper Rash  
Zinc Oxide
Therapeutics that treat diaper rash by forming a protective barrier against the skin.

Buyer Products:

  • Balmex (Zinc Oxide)
 
Pruritus  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Hydroxyzine Pamoate
 
Psoriasis
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation by inhibiting the accumulation of inflammatory cells like leucocytes and macrophages at the inflammation site.

Target Products:

  • Beta-Val (Betamethasone Valerate)
 
Vitamin D Analogs
Therapeutics that treat psoriasis by providing vitamin D-like compounds.

Buyer Products:

  • Sorilux (Calcipotriene)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skin disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK2245840 / SRT2104 (SIRT1 Activator)
  • 870086 (Glucocorticoid Agonist)
 
Digestive System
Gall Bladder Disorders  
Cholelithiasis (Gallstones)  
Anticholelithic Agents
Therapeutics that treat gall stones by decreasing the liver's cholesterol synthesis and secretion.

Target Products:

  • Ursodiol
 
Gastrointestinal Tract Disorders
Gastroduodenal Disorders
Peptic Ulcers
Duodenal
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Axid (Nizatidine)
  • Zantac (Ranitidine Hydrochloride)

Target Products:

  • Ranitidine HCl
  • Famotidine
  • Cimetidine
  • Nizatidine
Proton Pump Inhibitors
Therapeutics that treat peptic ulcers by inhibiting the membrane protein involved in the final steps of triggering acid release into the stomach.

Target Products:

  • Lansoprazole Delayed-Release Capsules
 
Ulcer Adhering Agents
Therapeutics that treat peptic ulcers by binding to it and protecting it from further damage.

Target Products:

  • Sucralfate
 
Gastric
Antisecretory Agents
Therapeutics that treat peptic ulcers by preventing the secretion of acid.

Target Products:

  • Misoprostol
 
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Axid (Nizatidine)
  • Zantac (Ranitidine Hydrochloride)

Target Products:

  • Ranitidine HCl
  • Famotidine
  • Cimetidine
  • Nizatidine
Zollinger-Ellison Syndrome
H2 Receptor Antagonists
Therapeutics that treat ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Zantac (Ranitidine Hydrochloride)

Target Products:

  • Ranitidine HCl
  • Famotidine
Proton Pump Inhibitors
Therapeutics that treat ulcers by inhibiting the membrane protein involved in the final steps of triggering acid release into the stomach.

Target Products:

  • Lansoprazole Delayed-Release Capsules
  • Pantoprazole Sodium Delayed Release
  • Pantoprazole Sodium Injection
 
Gastroesophageal Disorders
Abdominal Gas  
Gas Bubble Surface Tension Reducing Agents
Therapeutics that treat abdominal gas by reducing the surface tension of gas bubbles in the bowels.

Target Products:

  • Genasyme (Simethicone)
 
Acid Indigestion/Heartburn
Acid Neutralizing Agents
Therapeutics that treat heartburn by neutralizing stomach acid.

Buyer Products:

  • TUMS (Calcium Carbonate)

Target Products:

  • Genaton (Alumina, Magnesium Trisilicate, Sodium Bicarbonate)
  • Antacid (Calcium Carbonate)
  • Alamag Antacid (Alumina and Magnesia)
H2 Receptor Antagonists
Therapeutics that treat indigestion by blocking the action of histamine at the H2 receptors.

Buyer Products:

  • Axid (Nizatidine)

Target Products:

  • Famotidine
  • Cimetidine
  • Nizatidine
Proton Pump Inhibitors
Therapeutics that treat heartburn by inhibiting the action of the membrane protein involved in the final steps of triggering acid release into the stomach.

Target Products:

  • Pantoprazole Sodium Delayed Release
  • Omeprazole Delayed-Release Capsules
 
Erosive Esophagitis
H2 Receptor Antagonists
Therapeutics that treat Erosive Esophagitis by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Axid (Nizatidine)
  • Zantac (Ranitidine Hydrochloride)

Target Products:

  • Ranitidine HCl
  • Nizatidine
Monoclonal Antibodies
Therapeutics that treat Esophagitis by interfering with specific immune pathways implicated in the progression of the disease.

Target Products:

  • Cephalon, Inc. - Cinquil (Reslizumab)
 
Proton Pump Inhibitors
Therapeutics that treat Erosive Esophagus by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Target Products:

  • Lansoprazole Delayed-Release Capsules
  • Pantoprazole Sodium Delayed Release
  • Pantoprazole Sodium Injection
 
Gastroesophageal Reflux Disease (GERD)
Dopamine Receptor Blocking Agents
Therapeutics that treat Gastroesophageal Reflux Disease (GERD) by blocking dopamine receptor and stimulating gastrointestinal movement without stimulating secretions from the pancreas, stomach or gall bladder.

Target Products:

  • Metoclopramide HCl
 
H2 Receptor Antagonists
Therapeutics that treat Gastroesophageal Reflux Disease by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Buyer Products:

  • Axid (Nizatidine)
  • Zantac (Ranitidine Hydrochloride)
  • Zantac EFFERdose (Ranitidine Hydrochloride Effervescent)

Target Products:

  • Ranitidine HCl
  • Famotidine
  • Cimetidine
  • Nizatidine
Proton Pump Inhibitors
Therapeutics that treat Gastroesophageal Reflux Disease by inhibiting the membrane protein involved in the final steps of triggering acid release into the stomach.

Target Products:

  • Lansoprazole Delayed-Release Capsules
  • Pantoprazole Sodium Delayed Release
  • Pantoprazole Sodium Injection
 
Gastroparesis  
Dopamine Receptor Blocking Agents
Therapeutics that treat gastroparesis by blocking the action of dopamine.

Target Products:

  • Metoclopramide HCl
 
Nausea/Vomiting
Dopamine Receptor Blocking Agents
Therapeutics that treat or prevent nausea and vomiting by blocking the action of dopamine.

Target Products:

  • Metoclopramide HCl
  • Prochlorperazine Maleate
 
Neurokinin-1 (NK-1) Receptor Antagonists
Therapeutics that prevent or treat nausea and vomiting by inhibiting the neurotransmitter NK-1 (Substance P) from binding to its receptors.

Buyer Products:

  • Rezonic (Casopitant)
 
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Buyer Products:

  • Zofran/Zofran ODT (Ondansetron Hydrochloride)

Target Products:

  • Ondansetron Hydrochloride Injection
  • Granisetron Hydrochloride
Intestinal Disorders
Constipation
Chronic
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Buyer Products:

  • Citrucel (Methylcellulose)

Target Products:

  • Genfiber (Psyillum)
Impacted Bowels  
Hyperosmotic Agents
Therapeutics that treat constipation by causing fluid overload, which in turn induces liquid stool within a short period of time.

Target Products:

  • Milk Of Magnesia (Magnesium Hydroxide)
  • Lactulose
 
Stimulants
Therapeutics that treat constipation by stimulating the contraction of bowels by addition of fiber or other substances.

Target Products:

  • Senna-Gen (Senna)
  • Reliable Gentile Laxatives (Bisacodyl)
 
Irregular Bowel Movements  
Bulk-Forming Agents
Therapeutics that treat constipation by stimulating the formation of bodies of feces that are able to be passed through the bowels.

Target Products:

  • Genfiber (Psyillum)
 
Stimulants
Therapeutics that treat constipation by stimulating the contraction of bowels by addition of fiber or other substances.

Target Products:

  • Senna-Gen (Senna)
  • Reliable Gentile Laxatives (Bisacodyl)
 
Diarrhea  
Antiperistaltic Agents
Therapeutics that treat diarrhea by inhibiting the wavelike motion of the digestive tract.

Target Products:

  • Diphenoxylate HCl/Atropine Sulfate
  • Loperamide Hydrochloride
 
Inflammatory Bowel Disease (IBD)
Crohn`s Disease  
CCR-9 Antagonists
Therapeutics that treat Crohn's Disease by blocking expression of chemokine receptors responsible for GI tract inflammation.

Buyer Products:

  • GSK1605786 (Orally Bioavailable CCR9 Antagonist)
 
Ulcerative Colitis  
Cyclooxygenase Inhibitors (COX Inhibitors)/Lipoxygenase Inhibitors
Therapeutics that treat ulcerative colitis by inhibiting the actions of the two enzymes, cyclooxygenase and lipoxygenase.

Target Products:

  • Mesalamine Rectal Suspension Enema
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation associated with ulcerative colitis by preventing the accumulation of inflammatory cells like leukocytes and macrophages to the inflammation site.

Target Products:

  • Hydrocortisone Enema
 
Intestinal Intubation  
Dopamine Receptor Blocking Agents
Therapeutics that cause bowel evacuation prior to intubation by blocking the action of dopamine.

Target Products:

  • Metoclopramide HCl
 
Stomatognathic Disorders  
Toothaches  
Sodium Channel Blocking Agents
Therapeutics that treat toothache by numbing a localized area.

Target Products:

  • Lidocaine Hydrochloride
 
Liver Disorders
Cirrhosis  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that prevent edema by excretion of sodium, potassium, chloride ions, and water in urine.

Target Products:

  • Furosemide
  • Torsemide
  • Bumetanide
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Target Products:

  • Triamterene and Hydrochlorothiazide
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Hydrochlorothiazide
 
Hepatitis
Hepatitis B
Chronic
Reverse Transcriptase Inhibitors (Nucleoside Analogs)
Therapeutics that treat hepatitis by inhibiting the action of reverse transcriptase, an enzyme necessary for DNA synthesis using an RNA template.

Buyer Products:

  • Epivir-HBV/Zeffix (Lamivudine)

Target Products:

  • Tenofovir Disoproxil Fumarate
Hepatitis C  
Chronic  
Nucleoside/Nucleotide Analogs
Therapeutics that treat hepatitis by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Target Products:

  • Ribavirin
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK2336805 (NS5A Inhiibitor)
  • GSK1399686 (Anti-Inflammatory Macrolide Conjugate)
  • GSK962040 (Motilin Receptor Agonist)
  • Solabegron (Beta-3 Adrenergic Agonist)
  • GSK1070806 (IL18 Monoclonal Antibody)
  • GW876008 (CRF1 Antagonist)
  • GSK1322888 (Motilin Receptor Agonist)
  • GSK2485852 (NS5B Inhibitor)

Target Products:

  • Laquinimod
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Regulus Therapeutics - Anti-miR-122 (microRNA Targeting Antisense Therapeutic)
 
Endocrinology/Metabolism
Diabetes
Induced Complications  
Central Diabetes Insipidus  
Antidiuretic Agents
Therapeutics that treat prevent the lose of water in the urine.

Target Products:

  • Desmopressin Acetate
 
Diabetic Nephropathy  
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat hypertension by regulating the blood vessel dilation.

Target Products:

  • Captopril
 
Angiotensin II Receptor Antagonists
Therapeutics that treat diabetes induced kidney disease by blocking the angiotensin II receptor.

Target Products:

  • Losaratan Potassium
  • Irbesartan
 
Insulin Dependent Diabetes Mellitus (IDDM)/Type 1 Diabetes
Immunomodulators
Therapeutics that treat Insulin Dependent Diabetes Mellitus by modulating the immune response that causes the destruction of insulin producing beta cells.

Target Products:

  • DiaPep277
 
Monoclonal Antibodies
Therapeutics that treat Insulin Dependent Diabetes Mellitus by modulating of immune pathways implicated in the progression of the disease.

Buyer Products:

  • Otelixizumab (Anti-CD3 Monoclonal Antibody)
 
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes
Biguanides
Therapeutics that treat abnormally high blood glucose levels by decreasing the production of glucose in the liver, decreasing intestinal absorption of glucose and increasing peripheral uptake and utilization of glucose.

Target Products:

  • Metformin HCl
 
Biguanides/Insulin Stimulating Agents
Therapeutics that control high blood sugar by stimulating the release of insulin as well as decreasing the production of glucose in the liver.

Target Products:

  • Metformin Hydrochloride/Glipizide
  • Metformin/Glyburide
 
Biguanides/Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Therapeutics that control high blood sugar by stimulating the release of insulin as well as sensitizing organs to insulin.

Buyer Products:

  • Avandamet (Rosiglitazone Maleate/Metformin)
  • Avandamet XR (Rosiglitazone Maleate/Metformin)

Target Products:

  • Rosiglitazone Maleate/Metformin
Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 Receptor Agonists)
Therapeutics that treat non-insulin dependent diabetes by stimulating the Glucagon-Like Peptide (GLP) receptor. GLP regulates gastric emptying, insulin secretion, food intake, and glucagon secretion.

Buyer Products:

  • Syncria (Albiglutide)
 
Insulin Stimulating Agents (Non-Sulfonylureas)
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin.

Target Products:

  • Nateglinide
 
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin.

Target Products:

  • Tolazamide
  • Glipizide
  • Glyburide
  • Glimepiride
 
Insulin Stimulating Agents (Sulfonylureas)/PPAR Agonists
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin and sensitizing organs to insulin.

Buyer Products:

  • Avandaryl (Rosiglitazone Maleate/Glimepiride)
 
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Products that sensitize organs to insulin.

Buyer Products:

  • Avandia (Rosiglitazone Maleate)

Target Products:

  • Rosiglitazone Maleate
  • Pioglitazone Hydrochloride
General Hormone Treatments  
Dexamethasones
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Target Products:

  • Dexamethasone Sodium
 
Prednisolones
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Target Products:

  • Methylprednisolone Acetate
 
Prednisones
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Target Products:

  • Prednisone
 
Hyperglycemia  
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that stimulate the secretion of insulin.

Target Products:

  • Glipizide
 
Intermediary Metabolism Disorders
Carnitine Deficiency  
Fatty Acid Transporters
Therapeutics that treat the depletion of long-chain fatty acids in the mitochondrial matrix by increasing carnitine level in the plasma, which facilitate the entry of long-chain fatty acids into the mitochondria.

Target Products:

  • Levocarnitine
 
Gout  
Gouty Arthritis  
Urate Resorption Inhibitors
Therapeutics that treat gouty arthritis by preventing the active re-absorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate.

Target Products:

  • Probenecid
 
Urate Resorption Inhibitors/Urate Crystallization Inhibitors
Therapeutics that treat gouty arthritis by preventing the active re-absorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate as well as preventing the deposition of excess urate crystals in the joints.

Target Products:

  • Probenecid/Colchicine
 
Hyperuricemia  
Urate Resorption Inhibitors
Therapeutics that inhibit the resorption of urate from the kidneys.

Target Products:

  • Probenecid
 
Hypercholesterolemia
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Atorvastatin Calcium Tablets
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Mevacor OTC (Lovastatin)

Target Products:

  • Rosuvastatin
  • Fluvastatin
  • Lovastatin
  • Pravastatin Sodium
  • Simvastatin
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that reduce cholesterol levels by reducing the levels of low-density lipoproteins (LDL) and increasing levels of high-density lipoproteins (HDL).

Target Products:

  • Fenofibrate
 
Hyperlipidemia
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Rosuvastatin
  • Fluvastatin
  • Pravastatin Sodium
  • Simvastatin
 
Omega-3 Acid Ethyl Esters
Omega-3 acid ethyl ester therapeutics that lower excessive triglyceride levels.

Buyer Products:

  • Lovaza (Omega-3 Acid Ethyl Ester)
 
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that treat hypercholesterolemia by reducing the levels of very low-density lipoprotein and increasing levels of high-density lipoproteins.

Target Products:

  • Gemfibrozil
  • Fenofibrate
 
Lysosomal Storage Diseases  
Fabry Disease  
Enzyme Replacement Therapy
Therapeutics that treat Fabry's Disease by providing the missing enzymes that contributes to the disease symptoms.

Buyer Products:

  • Amicus Amigal/AT1001 (Migalastat Hydrochloride)
  • Amigal/AT1001 (Migalastat Hydrochloride)
 
Parathyroid Gland Disorders  
Hyperparathyroidism (HPT)  
Calcimimetic Agents
Therapeutics that treat hyperparathyroidism by decreasing parathyroid hormone levels, which may provide effective reduction of calcium levels.

Target Products:

  • Cinacalcet
 
Vitamin D Analogs
Therapeutics that act similar to Vitamin D.

Target Products:

  • Paricalcitol
  • Calcitriol
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Amicus Amigal/AT1001 (Migalastat Hydrochloride)
  • GSK2245840 / SRT2104 (SIRT1 Activator)
  • GSK1292263 (G-Protein Coupled Receptor 119 (GPR 119) Agonist)
  • GSK1614235 (SGLT1 Inhibitor)
  • GSK1362885 (Glycogen Phosphorylase Inhibitor)
  • 189075 (Remoglifozin Etabonate)
  • GSK376501 (PPAR Gamma Partial Agonist)
  • 184072 (SIRT1 Activator)
  • SB756050 (Bile Acid Receptor Agonist)
  • GSK256073 (Nicotinic Acid Receptor Agonist)
  • GSK232802 (Selective Estrogen Receptor Modulator)
  • Otelixizumab (Anti-CD3 Monoclonal Antibody)
  • Avandia (Rosiglitazone Maleate)
  • GSK1070806 (IL18 Monoclonal Antibody)
 
Pituitary Gland Disorders  
Acromegaly  
Somatostatin Analogs
Therapeutics that prevents the secretion of growth hormones.

Target Products:

  • Octreotide Acetate
 
Hyperprolactenemia  
Dopamine Receptor Agonists
Products that stimulate the dopamine receptor.

Target Products:

  • Cabergoline
 
Severe Short Stature  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Target Products:

  • TEV-TROPIN (Recombinant Somatropin)
 
Reproductive Disorders  
Abnormal Puberty  
Precocious  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat abnormal puberty by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Leuprolide
 
Amenorrhea  
Progestins
Female sex hormone necessary for the development of the female reproductive system.

Target Products:

  • Progesterone Capsules
 
Hypogonadism  
Male  
Androgens
Therapeutics that are male sex hormones.

Target Products:

  • Testosterone Cypionate Injection
  • Bio-T-Gel (Testosterone Gel)
 
Menopause  
Estrogens/Progestins
Therapeutics that are mixture of two female sex hormones that are important for the development of the female reproductive system.

Target Products:

  • Estradiol/Norethindrone Acetate
 
Hematology
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • LGD-4665 (Thrombopoietin Oral Mimetic)
  • GSK1278863 (Prolyl Hydroxylase Inhibitor)
  • 2285921 (Thrombopoietin Receptor Agonist)
  • Promacta (Eltrombopag)
  • GSK256073 (Nicotinic Acid Receptor Agonist)

Target Products:

  • Omapro (Omacetaxine Mepesuccinate)/Formerly Ceflatonin
  • Cephalon, Inc. - Trisenox (Arsenic Trioxide)
  • BioGeneriX AG Anemia Biologics Program
Red Blood Cell (RBC) Disorders  
Anemia  
Folic Acid Derivatives
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues caused by folic acid deficiency.

Target Products:

  • Leucovorin Calcium
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in very early stages of research where no human subject is involved.

Target Products:

  • BioGeneriX AG Anemia Biologics Program
  • BioGeneriX AG Neutropenia Biologics Program
 
Serum Factor Disorders
Hypercalcemia  
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat a disorder characterized by excessive calcium levels by inhibiting the resorption of bone.

Target Products:

  • Pamidronate Disodium
  • Teva Parenteral Zoledronic Acid Injection
 
Hypercholesterolemia
Calcium Channel Blocking Agents/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat high blood pressure and high cholesterol by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine, and by blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Atorvastatin Calcium Tablets
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Buyer Products:

  • Mevacor OTC (Lovastatin)

Target Products:

  • Rosuvastatin
  • Fluvastatin
  • Lovastatin
  • Pravastatin Sodium
  • Simvastatin
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that treat hypercholesterolemia by reducing the levels of very low-density lipoprotein and increase levels of high-density lipoproteins.

Target Products:

  • Fenofibrate
 
Hyperglycemia  
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that stimulate the secretion of insulin.

Target Products:

  • Glipizide
 
Hyperlipidemia
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Rosuvastatin
  • Fluvastatin
  • Pravastatin Sodium
  • Simvastatin
 
Omega-3 Acid Ethyl Esters
Omega-3 acid ethyl ester therapeutics that lower excessive triglyceride levels.

Buyer Products:

  • Lovaza (Omega-3 Acid Ethyl Ester)
 
Plasma Triglyceride Reducing Agents (Fibrate Compounds)
Therapeutics that reduce the levels of very low-density lipoprotein and increasing levels of high-density lipoproteins.

Target Products:

  • Gemfibrozil
  • Fenofibrate
 
Hyperphosphatemia  
Phosphate Binding Agents
Therapeutics that bind blood phosphorous.

Target Products:

  • Lathanum Carbonate
 
Hyperuricemia  
Urate Resorption Inhibitors
Therapeutics that prevents the resorption of urate within the kidneys.

Target Products:

  • Probenecid
 
Hypocalcemia  
Vitamin D Analogs
Therapeutics that treat hypocalcemia by increasing serum levels of calcium, as well as helping the bone calcification process.

Target Products:

  • Calcitriol
 
Hypokalemia  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat hypokalemia by promoting excretion while inhibiting the removal of potassium.

Target Products:

  • Triamterene and Hydrochlorothiazide
 
Thrombocyte (Platelet) Disorders
Thrombocythemia  
Megakaryocyte Maturation Inhibitors
Therapeutics that prevents the maturation of platelet producing cells.

Target Products:

  • Anagrelide
 
Thrombocytopenia  
Thrombopoietin Agonists
Therapeutics that treat thrombocytopenia by stimulating thrombopoietin, which promotes the production of platelets.

Buyer Products:

  • Promacta (Eltrombopag)
 
White Blood Cell (WBC) Disorders  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics that treat neutropenia by inducing the maturation and proliferation of white blood cells.

Target Products:

  • ratiopharm - Lipegfilgrastim/Formerly XM22
  • CG-10639 / Formerly Neugranin (Human Albumin-Human G-CSF)
  • Neutroval (Filgrastim)/Generic Neupogen/Formerly XM02
 
Immunology
Autoimmune Disorders
Arthritis
Rheumatoid Arthritis (RA)
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by selectively blocking cyclooxygenase 2 activity.

Target Products:

  • Cephalon, Inc. - CEP-33222/AI-525 (Intravenous Celecoxib)
  • Meloxicam
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Target Products:

  • Nabumetone
  • Genacote
  • Fenoprofen Calcium
  • Tolmetin
  • Piroxicam
  • Naproxen/Naproxen Delayed Release
  • Diflunisal
  • Diclofenac Sodium
  • Diclofenac Potassium
  • Ketoprofen
  • Flurbiprofen
  • Etodolac
  • Oxaprozin
  • ASA (Aspirin)
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Pyrimidine Synthesis Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the overproduction of immune cells.

Target Products:

  • Leflunomide
 
Immunotherapy
Immunosuppressants
Therapeutics that treat chronic inflammation of the joints by inhibiting a full immune response.

Target Products:

  • Hydroxychloroquine Sulfate
 
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Arzerra (Ofatumumab)
 
Idiopathic Thrombocytopenia Purpura (ITP)  
Thrombopoietin Agonists
Therapeutics that treat thrombocytopenia by stimulating thrombopoietin, which promotes the production of platelets.

Buyer Products:

  • Promacta (Eltrombopag)
 
Inflammatory Bowel Disease (IBD)  
Crohn`s Disease  
CCR-9 Antagonists
Therapeutics that treat Crohn's Disease by blocking expression of chemokine receptors responsible for GI tract inflammation.

Buyer Products:

  • GSK1605786 (Orally Bioavailable CCR9 Antagonist)
 
Lupus Erythematosus
Discoid (DLE)  
Immunosuppressants
Therapeutics that treat an autoimmune disease characterized by disk-shaped skin plaques by inhibiting a full immune response.

Target Products:

  • Hydroxychloroquine Sulfate
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat an autoimmune disease characterized by disk-shaped skin plaques using a steroidal compound.

Target Products:

  • Beta-Val (Betamethasone Valerate)
 
Systemic (SLE)
Anti-dsDNA Inhibitors
Therapeutics that treat systemic lupus by selectively reducing antibodies to double-stranded DNA (dsDNA).

Target Products:

  • Cephalon, Inc. - Lupuzor (CD4 T-Cell Modulator)
 
Hormonal
Therapeutics that treat systemic lupus with hormones.

Buyer Products:

  • Genelabs Prestara (Prasterone)
 
Immunosuppressants
Therapeutics that treat systemic lupus by inhibiting a full immune response.

Target Products:

  • Hydroxychloroquine Sulfate
  • Mycophenolate Mofetil
 
Monoclonal Antibodies
Therapeutics that treat systemic lupus by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Buyer Products:

  • Benlysta (Belimumab)/Formerly LymphoStat-B
 
Multiple Sclerosis (MS)  
Immunomodulators
Therapeutics that treat a neurodegenerative disease characterized by the gradual accumulation of plaques on the nerve sheaths by altering the immune mechanisms.

Target Products:

  • Copaxone (Glatiramer Acetate)
  • Laquinimod
 
Psoriasis
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat a chronic autoimmune disease characterized by softening, separating, causing the shedding of the horny layer of the skin with a steroidal compound.

Target Products:

  • Beta-Val (Betamethasone Valerate)
 
Vitamin D Analogs
Therapeutics that treat a chronic autoimmune disease characterized by softening, separating, causing the shedding of the horny layer of the skin by inhibiting the proliferation of skin cells.

Buyer Products:

  • Sorilux (Calcipotriene)
 
Immune Deficiency Disorders
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • ViiV Healthcare - Selzentry (Maraviroc)
 
Integrase Inhibitors
Therapeutics that help manage HIV by blocking the integration of the HIV virus' genetic material into the host cell.

Buyer Products:

  • ViiV Healthcare - GSK1349572 / Dolutegravir (Integrase Inhibitor)
 
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare - Rescriptor (Delavirdine Mesylate)
 
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare - Epzicom (Abacavir/Lamivudine)
  • ViiV Healthcare - Epivir (Lamivudine)
  • ViiV Healthcare - Combivir (Lamivudine/Zidovudine)
  • ViiV Healthcare - Retrovir (Zidovudine)
  • ViiV Healthcare - Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • ViiV Healthcare - Ziagen (Abacavir Sulfate)

Target Products:

  • Abacavir/Lamivudine
  • Didanosine
  • Tenofovir Disoproxil Fumarate
Nucleoside and Non-Nucleoside Reverse Transcriptase Inhibitors (NRTI/NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Target Products:

  • Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • ViiV Healthcare - Viracept (Nelfinavir Mesylate)
  • ViiV Healthcare - Lexiva (Fosamprenavir Calcium)
 
Severe Combined Immunodeficiency Disease (Bubble Boy Disease)  
Enzymatic Agents
Therapeutics that treat a rare inherited disorder characterized by impairment or absence of the immune system at birth by replacing enzymes essential for normal immune system development.

Buyer Products:

  • GSK2696273 (Adenosine Deaminase)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • ViiV Healthcare - GSK1265744 (Integrase Inhibitor)
  • ViiV Healthcare - PF-232798
  • ViiV Healthcare - PF-3716539 (PK Enhancer)
  • GSK1070806 (IL18 Monoclonal Antibody)
  • Human Immunodeficiency Virus (HIV) Vaccine
  • Otelixizumab (Anti-CD3 Monoclonal Antibody)
  • Firategrast/SB683699
  • 681323 (p38 Kinase Inhibitor)
  • GSK315234A (Monoclonal Antibody)
  • GSK1827771 (Interleukin-1 (IL-1) Antagonist)
  • Lersivirine/ViiV Healthcare UK-453061 (Non-Nucleotide Reverse Transcriptase Inhibitor)
  • GSK1399686 (Anti-Inflammatory Macrolide Conjugate)
  • Conjugated Hepatavalent Combination Vaccine
  • GSK2018682 (Sphingosine-1 Phosphate Receptor (S1P))
  • Benlysta (Belimumab)/Formerly LymphoStat-B
  • CCX354 (CCR1 Receptor Antagonist)
  • GSK2245840 / SRT2104 (SIRT1 Activator)
  • Arzerra (Ofatumumab)
  • 2285921 (Thrombopoietin Receptor Agonist)
  • ViiV Healthcare - GSK2248761/IDX899 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • DV1179 (TLR Inhibitor)
  • Losmapimod (p38 Kinase Inhibitor)

Target Products:

  • Edratide (TV-4710)
  • TV1102 (Antisense VLA-4 Inhibitor)/Formerly ATL1102
  • Laquinimod
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • OP-R003 (Human Anti-Interleukin-6 Antibody)
  • Regulus Therapeutics-GSK microRNA Product

Target Products:

  • BioGeneriX AG Multiple Sclerosis Biologics Program
  • Cephalon, Inc. - CEP-37248/Formerly ART123 (Anti-IL 12/23)
  • Edratide (TV-4710)
Infectious Diseases
Bacterial
Antibacterial Agents
Broad Spectrum
Antibiotics
Aminoglycosides
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis.

Target Products:

  • Tobramycin Sulfate
  • Amikacin Sulfate
 
Cephalosporin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Zinacef (Cefuroxime)
  • Fortaz (Ceftazidime)
  • Ceftin (Cefuroxime Axetil)

Target Products:

  • Ceftriaxone Sodium
  • Cefadroxil
  • Cefaclor
  • Cefuroxime Axetil
  • Cephalexin
  • Cefaclor ER
  • Cefdinir Tablets/Oral Suspension
  • Cefprozil Tablets/Oral Suspension
Lincosamides
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis.

Target Products:

  • Clindamycin HCl
 
Macrolides
Therapeutics that treat a wide variety of infections by inhibiting RNA-dependent bacterial protein synthesis.

Target Products:

  • Azithromycin
  • Clarithromycin
  • Clarithromycin XL Filmtabs
 
Nitroimidazoles
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis and causing cell death.

Target Products:

  • Metronidazole
 
Oxazolidinones
Therapeutics that treat a wide variety of infections by inhibiting early initiation of bacterial protein synthesis.

Target Products:

  • Linezolid
 
Penicillin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication.

Target Products:

  • Penicillin-VK
  • Dicloxacillin
  • Amoxicillin
 
Penicillin Derivatives/Beta-Lactamase Inhibitors
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis during active multiplication and increasing susceptibility to penicillin derived compounds.

Buyer Products:

  • Timentin (Ticarcillin Disodium/Clavulanate Potassium)

Target Products:

  • Amoxicillin/Clavulanate Potassium
Pleuromutilins
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis through binding onto ribosome.

Buyer Products:

  • Altabax (Retapamulin)
 
Pseudominic Acids
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis and RNA synthesis.

Buyer Products:

  • Bactroban Nasal (Mupirocin Calcium)
  • Bactroban (Mupirocin Calcium)
  • Bactroban Ointment (Mupirocin)

Target Products:

  • Mupirocin
Quinolones/Fluoroquinolones
Therapeutics that treat a wide variety of infections by promoting breakage of bacterial DNA strands.

Target Products:

  • Levofloxacin
  • Moxifloxacin HCl
  • Ciprofloxacin
  • Gatifloxacin
  • Ofloxacin
 
Sulfonamides
Therapeutics that treat a wide variety of bacterial infections by inhibiting folic acid synthesis.

Target Products:

  • Sulfisoxazole
 
Tetracyclines
Therapeutics that treat a wide variety of infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Target Products:

  • Tetracycline HCl
  • Doxycycline Hyclate
  • Minocycline HCl
 
Narrow Spectrum
Dermatology  
Skin/Soft Tissue Infections  
Aminoglycosides/Polypeptides
Therapeutics that treat dermal infections by inhibiting bacterial cell wall synthesis.

Target Products:

  • Triple Antibiotic Ointment
  • Neomycin Sulfate
 
Digestive System  
Gingivitis  
Chlorhexidines
Therapeutics that treat inflammation of the gums by causing leakage in bacterial cell walls.

Target Products:

  • Chlorhexidine Gluconate
 
Periodontitis  
Tetracyclines
Therapeutics that treat bacterial infections of the gums, teeth, and underlying bone by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Target Products:

  • Doxycycline Hyclate
 
Musculoskeletal System
Bone/Joint Infections
Cephalosporin Derivatives
Therapeutics that treat bacterial infections manifested in the bones or joints by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Zinacef (Cefuroxime)
  • Ceftin (Cefuroxime Axetil)

Target Products:

  • Cefuroxime Axetil
Neurology  
Meningitis  
Cephalosporin Derivatives
Therapeutics that treat inflammation of the lining of the brain and spinal cord by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Zinacef (Cefuroxime)
 
Ophthalmology  
Conjunctivitis  
Mast Cell Stabilizers
Therapeutics that treat inflammation of the clear membrane outside the eye preventing the mast cell release of histamine.

Target Products:

  • Cromolyn Sodium
 
Keratitis  
Mast Cell Stabilizers
Therapeutics that treat inflammation of the cornea caused by bacterial infection by inhibiting the release of histamine and leukotrienes from mast cells.

Target Products:

  • Cromolyn Sodium
 
Keratoconjunctivitis  
Mast Cell Stabilizers
Therapeutics that treat inflammation of the cornea and the clear membrane outside the eye caused by bacterial infection by blocking the release of histamines from mast cells.

Target Products:

  • Cromolyn Sodium
 
Ocular Infections  
Aminoglycosides/Polypeptides
Therapeutics that treat bacterial infections of the eye by inhibiting bacterial protein synthesis and damaging the cell membrane.

Target Products:

  • Neomycin Sulfate
 
Otolaryngology (Ear/Nose/Throat)  
Otitis Media  
Macrolides
Therapeutics that treat infection and inflammation of the middle ear space and ear drum by inhibiting RNA-dependent bacterial protein synthesis.

Target Products:

  • Azithromycin
 
Respiratory System
Bronchitis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the bronchi in the lungs by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Target Products:

  • Sulfamethoxazole/Trimethoprim
 
Pharyngitis
Cephalosporin Derivatives
Therapeutics that treat inflammation of the cone shaped cavity at the back of the mouth caused by bacterial infection by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)

Target Products:

  • Cefuroxime Axetil
Pneumonia  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat inflammation of the lungs caused by bacterial infection by inhibiting folic acid synthesis and bacterial growth.

Target Products:

  • Sulfamethoxazole/Trimethoprim
 
Quinolones/Fluoroquinolones
Therapeutics that treat inflammation of the lungs caused by bacterial infection by bacterial infection by promoting breakage of bacterial DNA strands.

Target Products:

  • Levofloxacin
  • Ciprofloxacin
 
Respiratory Tract Infections
Cephalosporin Derivatives
Therapeutics that treat infections of the air passage caused by a wide variety of bacteria.

Buyer Products:

  • Zinacef (Cefuroxime)
  • Ceftin (Cefuroxime Axetil)

Target Products:

  • Cefuroxime Axetil
Quinolones/Fluoroquinolones
Therapeutics that treat bacterial infections of the air passage involved in breathing, including the trachea, lungs and bronchi by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Tonsilitis
Cephalosporin Derivatives
Therapeutics that treat inflammation of the lymphoid tissue on either side of the throat caused by bacterial infection by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Ceftin (Cefuroxime Axetil)

Target Products:

  • Cefuroxime Axetil
Urology  
Prostatitis  
Quinolones/Fluoroquinolones
Therapeutics that treat a wide variety of infections by promoting breakage of bacterial DNA strands.

Target Products:

  • Levofloxacin
  • Ciprofloxacin
 
Urinary Tract Infections (UTI)  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections of the urinary tract by inhibiting dihydrofolate reductase resulting in decreased bacterial nucleic acid/protein production.

Target Products:

  • Sulfamethoxazole/Trimethoprim
 
Nitrofurantoins
Therapeutics that treat bacterial infections of the urinary tract by inactivating/altering bacterial proteins and other macromolecules.

Target Products:

  • Nitrofurantoin
 
Quinolones/Fluoroquinolones
Therapeutics that treat bacterial infections of the urethra, urinary bladder, ureters, and kidneys by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Trimethoprim
Therapeutics that treat bacterial infections of the urethra, urinary bladder, ureters, and kidneys by blocking the action of bacterial dihydrofolate reductase.

Target Products:

  • Trimethoprim
 
Vaccines  
Bacterial  
Combination  
Diphtheria/Tetanus/Acellular Pertussis (DTaP)
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause diphtheria, tetanus, and acellular pertussis.

Buyer Products:

  • Boostrix (Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccine, Adsorbed (Tdap))
  • Infanrix (Diphteria And Tetanus Toxoids And Acellular Pertussis Vaccine Aborbed)
 
Single Target  
Haemophilus Influenzae Type B (Hib)
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause Haemophilus influenzae type B.

Buyer Products:

  • MenHibrix (Hib-MenCY-TT)
  • Hiberix (Haemophilus B Conjugate Vaccine)
 
Meningitis
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause meningitis.

Buyer Products:

  • Nimenrix (MenACWY-TT)
  • Mencevax
  • MenHibrix (Hib-MenCY-TT)
 
Streptococcus pneumoniae
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause pneumococcal bacteria.

Buyer Products:

  • Stretptococcus Pneumoniae Vaccine / Formerly GSK1024850A
  • Synflorix
 
Typhoid Fever
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to pathogens that cause typhoid fever.

Buyer Products:

  • Typherix (Purified Polysaccharide Antigen)
 
Bacterial/Viral
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to a bacterial or viral pathogen.

Buyer Products:

  • Pediarix
  • Kinrix (Diphtheria, Tetanus, Acellular Pertussis-Inactivated Polio Virus Vaccine (DTaP-IPV))
 
Helminthic
Ascariasis (Roundworms)  
Antimicrotubule Agents
Therapeutics that treat helminthic infections by disrupting the cell cycle of the worm.

Target Products:

  • Mebendazole
 
Enterobiasis (Pinworms)  
Antimicrotubule Agents
Therapeutics that treat helminthic infections by disrupting the cell cycle of the worm. itching.

Target Products:

  • Mebendazole
 
Hookworms  
Antimicrotubule Agents
Therapeutics that treat parasitic infections of the intestines.

Target Products:

  • Mebendazole
 
Hydatid Disease  
Antimicrotubule Agents
Therapeutics that treat parasitic infections characterized by formation of cysts in a several organs.

Buyer Products:

  • Albenza (Albendazole)
 
Neurocysticercosis  
Antimicrotubule Agents
Therapeutics that treat parasitic infections caused by a tapeworm in the brain.

Buyer Products:

  • Albenza (Albendazole)
 
Trichuriasis (Whipworms)  
Antimicrotubule Agents
Therapeutics that treat parasitic infections characterized by large worms attached to the lining of the large intestine.

Target Products:

  • Mebendazole
 
Mycological (Fungal)
Antifungal Agents
Broad Spectrum  
Azoles  
Imidazoles
Therapeutics that treat fungal infections by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Ketoconazole
 
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections by increasing permeability of the cell wall causing leakage of cellular contents.

Target Products:

  • Amphotericin B
 
Narrow Spectrum
Dermatology
Candidiasis  
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the skin caused by yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Nystatin
 
Onychomycosis (Nail)
Amine Derivatives  
Allyl
Therapeutics that treat fungal infections of the nail caused by yeast by causing a deficiency in the cell wall.

Target Products:

  • Terbinafine Hydrochloride
 
Azoles  
Triazoles
Therapeutics that treat fungal infections of the nail by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Itraconazole
 
Tinea Barbae  
Penicillin Derivatives
Therapeutics that treat fungal infections of the bearded area by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Tinea Capitis  
Penicillin Derivatives
Therapeutics that treat fungal infections of the scalp by inhibiting biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Tinea Corporis (Ringworm)  
Azoles  
Imidazoles
Therapeutics that treat fungal infections of the skin characterized by scaly, red rings by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Ketoconazole
  • Clotrimazole
 
Penicillin Derivatives
Therapeutics that treat fungal infections of the skin characterized by scaly, red rings by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Thiocarbamates
Therapeutics that treat fungal infections of the skin characterized by scaly, red rings by stunting the growth of the branching filaments.

Target Products:

  • Tolnaftate
 
Tinea Cruris (Jock Itch)  
Azoles  
Imidazoles
Therapeutics that treat fungal infections of the groin and perineum by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Ketoconazole
  • Clotrimazole
 
Penicillin Derivatives
Therapeutics that treat fungal infections of the groin and perineum by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Thiocarbamates
Therapeutics that treat fungal infections of the groin and perineum by stunting the growth of the branching filaments.

Target Products:

  • Tolnaftate
 
Tinea Pedis  
Azoles  
Imidazoles
Therapeutics that treat fungal infections of the feet by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Ketoconazole
  • Clotrimazole
 
Penicillin Derivatives
Therapeutics that treat fungal infections of the feet by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Thiocarbamates
Therapeutics that treat fungal infections of the feet by stunting the growth of the branching filaments.

Target Products:

  • Tolnaftate
 
Tinea Unquium  
Penicillin Derivatives
Therapeutics that treat fungal infections of the nails by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Tinea Versicolor  
Azoles  
Imidazoles
Therapeutics that treat fungal infections of skin exposed to the sun characterized by patches of depigmentation by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Clotrimazole
 
Penicillin Derivatives
Therapeutics that treat fungal infections of skin exposed to the sun characterized by patches of depigmentation by inhibiting the biosynthesis of cell walls.

Target Products:

  • Griseofulvin
 
Digestive System  
Mucous  
Candidiasis  
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the secretory lining of the tissues caused by a yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Nystatin
 
Nervous System  
Cryptococcal Meningitis  
Triazoles
Therapeutics that treat fungal infections of lining of the brain and the spinal cord by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Fluconazole
 
Otolaryngology (Ear/Nose/Throat)  
Esophageal Candidiasis  
Triazoles
Therapeutics that treat fungal infections of the esophagus caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Fluconazole
 
Oropharyngeal Candidiasis  
Azoles  
Triazoles
Therapeutics that treat fungal infections of the mouth and pharynx caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Fluconazole
 
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the mucosa caused by yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Nystatin
 
Respiratory System  
Pneumocystis Carinii Pneumonia (PCP)  
Protozoan Metabolism Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by preventing metabolism and growth in organism.

Buyer Products:

  • Mepron/Wellvone (Atovaquone)
 
Urology  
Vaginal Candidiasis  
Azoles  
Imidazoles
Therapeutics that treat fungal infections of the female reproductive organ caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Clotrimazole
 
Triazoles
Therapeutics that treat fungal infections of the female reproductive organ caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Fluconazole
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Buyer Products:

  • Tafenoquine (8-Aminoquinoline)
  • GSK1322322 (Polypeptide Deformylase Inhibitor)
  • GSK932121 (Plasmodium Electron Transport Chain Inhibitor)
  • PentaStaph Vaccine (Staphylococcus aureus Vaccine)
  • Genelabs Hepatitis E Vaccine
  • Sitamaquine (8-Aminoquinoline)
  • ViiV Healthcare - GSK2248761/IDX899 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • ViiV Healthcare - PF-3716539 (PK Enhancer)
  • ViiV Healthcare - PF-232798
  • ViiV Healthcare - GSK1265744 (Integrase Inhibitor)
  • NTHi-Pneumo
  • Epstein Barr Virus (EBV) Vaccine
  • Human Immunodeficiency Virus (HIV) Vaccine
  • Relenza (Zanamivir)
  • Cytomegalovirus Vaccine
  • Tuberculosis Vaccine
  • Farglitazar
  • GSK2485852 (NS5B Inhibitor)
  • GSK2336805 (NS5A Inhiibitor)
  • GSK2251052 / Formerly AN3365 (Leucyl T-RNA Synthetase Inhibitor (LeuRS Inhibitor))
  • Streptococcus pneumoniae Vaccine
  • Lersivirine/ViiV Healthcare UK-453061 (Non-Nucleotide Reverse Transcriptase Inhibitor)
  • GSK945237 (Topoisomerase II Inhibitor)
  • GSK580416 (Ribosome Inhibitor)
 
Protozoal
Antiprotozoal Agents
Broad Spectrum  
Nitroimidazoles
Therapeutics that treat infections caused by a wide variety of unicellular organisms by inhibiting protein synthesis and causing cell death.

Target Products:

  • Metronidazole
 
Sulfonamides
Therapeutics that treat infections caused by a wide variety of unicellular organisms by inhibiting folic acid synthesis.

Target Products:

  • Sulfisoxazole
 
Tetracyclines
Therapeutics that treat infections caused by a wide variety of unicellular organisms by inhibiting protein synthesis and causing cell death.

Target Products:

  • Tetracycline HCl
  • Doxycycline Hyclate
 
Narrow Spectrum  
Malaria  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by blocking the action of the dihydrofolate enzyme.

Buyer Products:

  • Malarone (Atovaquone/Proguanil)
  • Daraprim (Pyrimethamine)
 
Toxoplasmosis (Toxo)  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat infections caused by Toxoplasma gondii and characterized by lesions in the heart, brain, and eye by preventing folic acid synthesis.

Buyer Products:

  • Daraprim (Pyrimethamine)
 
Vaccines  
Malaria
Therapeutics that prevent or treat malaria infections, which are caused by protozoans of the genus Plasmodium.

Buyer Products:

  • Mosquirix (Malaria Vaccine)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in very early stages of research where no human subject is involved.

Buyer Products:

  • Relenza (Zanamivir)
  • Regulus Therapeutics - Anti-miR-122 (microRNA Targeting Antisense Therapeutic)
 
Viral
DNA Viruses
Hepadnavirus
Hepatitis B
Chronic
Reverse Transcriptase Inhibitors (Nucleoside Analogs)
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months by blocking enzyme essential for viral DNA synthesis.

Buyer Products:

  • Epivir-HBV/Zeffix (Lamivudine)

Target Products:

  • Tenofovir Disoproxil Fumarate
Herpesvirus
Herpes Labialis (Cold Sores)
Purine Nucleoside Analogs
Therapeutics that treat viral infections by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)

Target Products:

  • Valacyclovir Hydrochloride
  • Famciclovir
Viral Fusion Inhibitors
Therapeutics that treat cold sores by inhibiting fusion of viral material into human cell plasma membranes.

Buyer Products:

  • Abreva (Docosanol)
 
Herpes Simplex Type 1
Purine Nucleoside Analogs
Therapeutics that treat viral infections characterized by recurrent cold sores and fever blisters by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)

Target Products:

  • Valacyclovir Hydrochloride
  • Famciclovir
  • Acyclovir
Herpes Simplex Type 2
Purine Nucleoside Analogs
Therapeutics that treat viral infections characterized by recurring outbreaks of painful genital lesions by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)

Target Products:

  • Valacyclovir Hydrochloride
  • Famciclovir
  • Acyclovir
Varicella Zoster
Herpes Zoster (Shingles)
Purine Nucleoside Analogs
Therapeutics that treat viral infections that cause shingles in adults by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)

Target Products:

  • Valacyclovir Hydrochloride
  • Famciclovir
  • Acyclovir
Varicella (Chickenpox)
Purine Nucleoside Analogs
Therapeutics that treat viral infections that cause chicken pox in children by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Valtrex (Valacyclovir Hydrochloride)

Target Products:

  • Valacyclovir Hydrochloride
  • Acyclovir
RNA Viruses
Flavivirus  
Hepatitis C  
Chronic  
Nucleoside/Nucleotide Analogs
Therapeutics that treat hepatitis by inhibiting replication of viral DNA by incorporating themselves into growing viral DNA stands.

Target Products:

  • Ribavirin
 
Orthomyxovirus  
Influenza A  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza A virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Relenza (Zanamivir)
 
Influenza B  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza B virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Relenza (Zanamivir)
 
Retrovirus
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)
CCR-5 Inhibitors
Therapeutics that help manage HIV by blocking the virus from entering human cells.

Buyer Products:

  • ViiV Healthcare - Selzentry (Maraviroc)
 
Integrase inhibitors
Therapeutics that help manage HIV by blocking the integration of the HIV virus' genetic material into the host cell.

Buyer Products:

  • ViiV Healthcare - GSK1349572 / Dolutegravir (Integrase Inhibitor)
 
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare - Rescriptor (Delavirdine Mesylate)

Target Products:

  • Tenofovir Disoproxil Fumarate
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • ViiV Healthcare - Retrovir (Zidovudine)
  • ViiV Healthcare - Combivir (Lamivudine/Zidovudine)
  • ViiV Healthcare - Trizivir (Lamivudine/Zidovudine/Abacavir Sulfate)
  • ViiV Healthcare - Epivir (Lamivudine)
  • ViiV Healthcare - Epzicom (Abacavir/Lamivudine)
  • ViiV Healthcare - Ziagen (Abacavir Sulfate)

Target Products:

  • Abacavir/Lamivudine
  • Didanosine
  • Tenofovir Disoproxil Fumarate/Emtricitabine
Nucleoside and Non-Nucleoside Reverse Transcriptase Inhibitors (NRTI/NNRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Target Products:

  • Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • ViiV Healthcare - Viracept (Nelfinavir Mesylate)
  • ViiV Healthcare - Lexiva (Fosamprenavir Calcium)
 
Vaccines
Bacterial/Viral
Therapeutics that prevent or treat infectious disease by producing or artificially increasing immunity to a bacterial and viral pathogens.

Buyer Products:

  • Pediarix
  • Kinrix (Diphtheria, Tetanus, Acellular Pertussis-Inactivated Polio Virus Vaccine (DTaP-IPV))
 
Viral
Combination  
Hepatitis A/Hepatitis B
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to Hepatitis A and Hepatitis B viruses.

Buyer Products:

  • Twinrix
 
Measles/Mumps/Rubella
Therapeutics that prevent or treat viral infections by producing or artificially increasing immunity to measles, mumps, and rubella.

Buyer Products:

  • Priorix
 
Single Target
Adenoviruses
Therapeutics that prevent or treat viral infections which commonly cause upper respiratory infections, such as common cold.

Target Products:

  • Adenovirus Vaccine
 
Hepatitis A
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to the Hepatitis A virus.

Buyer Products:

  • Havrix (Hepatitis A Vaccine, Inactivated)
 
Hepatitis B
Therapeutics that prevent or treat viral infections of the liver by producing or artificially increasing immunity to the Hepatitis B virus.

Buyer Products:

  • Fendrix
  • Engerix-B
 
Herpes Simplex
Therapeutics that prevent or treat viral infections characterized by vesicular eruption by producing or artificially increasing immunity to the Herpes Simplex virus.

Buyer Products:

  • Simplirix Vaccine
 
Herpes Zoster (Shingles)
Therapeutics that prevent or treat viral infections that cause shingles in adults.

Buyer Products:

  • GSK1437173A
 
Influenza (Flu)
Therapeutics that prevent or treat viral infections of the respiratory tract by producing or artificially increasing immunity to the Influenza virus.

Buyer Products:

  • FluLaval (Influenza Virus Vaccine)
  • Pumarix (H5N1 Pandemic Flu Vaccine)
  • Fluarix (Influenza Vaccine, Inactivated Split Virion)
  • New Generation Influenza Vaccine (Flu Vaccine)
  • Pandemrix (H1N1 Influenza (Swine Flu Pandemic) Vaccine)
 
Papillomavirus
Therapeutics that prevent or treat viral infections characterized by the proliferation of epithelial cells, leading to the formation of warts and possibly other related diseases such as cervical pre-cancers and cervical cancer.

Buyer Products:

  • Cervarix (HPV16/HPV18 Vaccine)
 
Rabies
Therapeutics that prevent or treat viral infections that infect brain cells by producing or artificially increasing immunity to the rabies virus.

Buyer Products:

  • Rabies Vaccine Absorbed
 
Rotavirus
Therapeutics that prevent or treat viral infections that cause severe dehydrating diarrhea in children by producing or artificially increasing immunity to the rotavirus.

Buyer Products:

  • Rotarix (Rotavirus Vaccine)
 
Varicella-Zoster Virus (Chicken Pox)
Therapeutics that prevent or treat viral infections that cause a blistery red rash by producing or artificially increasing immunity to the Varicella Zoster virus.

Buyer Products:

  • Varilrix
 
Musculoskeletal System
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • CCX354 (CCR1 Receptor Antagonist)
  • Losmapimod (p38 Kinase Inhibitor)
  • Otelixizumab (Anti-CD3 Monoclonal Antibody)
  • Avandia (Rosiglitazone Maleate)
  • GSK274150 (Selective iNOS Inhibitor)
  • GSK315234A (Monoclonal Antibody)
  • GSK971086 (Androgen Modulator)
  • GSK1827771 (Interleukin-1 (IL-1) Antagonist)
  • Benlysta (Belimumab)/Formerly LymphoStat-B
  • 768974 (Parathyroid Hormone Agonist)
  • 681323 (p38 Kinase Inhibitor)
 
Skeletal Disorders
Bone Disorders
Osteoporosis
Hormonal Treatments  
Estrogens/Progestins
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Target Products:

  • Estradiol/Norethindrone Acetate
 
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts.

Buyer Products:

  • Boniva (Ibandronate Biphosphonate)

Target Products:

  • Alendronate Sodium
  • Risedronate Sodium
  • Teva Parenteral Ibandronate Sodium
  • Teva Parenteral Zoledronic Acid Injection
Receptor Activator Of Nuclear Factor-kB Ligand (RANKL) Inhibitors
Therapeutics that treat osteoporosis by inhibiting a mediator of osteoclast formation resulting in suppression of bone resorption.

Buyer Products:

  • Prolia (Denosumab)
 
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts while not stimulating the endometrial lining of the uterus.

Target Products:

  • Raloxifene Hydrochloride
 
Paget`s Disease  
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat paget's disease by inhibiting the loss of bone material by osteoclasts.

Target Products:

  • Alendronate Sodium
  • Risedronate Sodium
  • Pamidronate Disodium
  • Teva Parenteral Zoledronic Acid Injection
 
Joint Disorders
Ankylosing Spondylitis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Naproxen/Naproxen Delayed Release
  • Diclofenac Potassium
 
Gouty Arthritis  
Urate Resorption Inhibitors
Therapeutics that treat gouty arthritis by preventing the active re-absorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate.

Target Products:

  • Probenecid
 
Urate Resorption Inhibitors/Urate Crystallization Inhibitors
Therapeutics that treat gouty arthritis by preventing the active re-absorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate as well as preventing the deposition of excess urate crystals in the joints.

Target Products:

  • Probenecid/Colchicine
 
Osteoarthritis (OA)  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat inflammation by specifically inhibiting the action of cyclooxygenase-2.

Target Products:

  • Cephalon, Inc. - CEP-33222/AI-525 (Intravenous Celecoxib)
  • Meloxicam
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Nabumetone
  • Genacote
  • Fenoprofen Calcium
  • Tolmetin
  • Piroxicam
  • Naproxen/Naproxen Delayed Release
  • Diflunisal
  • Diclofenac Sodium
  • Diclofenac Potassium
  • Ketoprofen
  • Flurbiprofen
  • Etodolac
  • Oxaprozin
  • ASA (Aspirin)
 
Rheumatoid Arthritis (RA)
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by selectively blocking cyclooxygenase 2 activity.

Target Products:

  • Cephalon, Inc. - CEP-33222/AI-525 (Intravenous Celecoxib)
  • Meloxicam
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Target Products:

  • Nabumetone
  • Genacote
  • Fenoprofen Calcium
  • Tolmetin
  • Piroxicam
  • Naproxen/Naproxen Delayed Release
  • Diflunisal
  • Diclofenac Sodium
  • Diclofenac Potassium
  • Ketoprofen
  • Flurbiprofen
  • Etodolac
  • Oxaprozin
  • ASA (Aspirin)
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Pyrimidine Synthesis Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the overproduction of immune cells.

Target Products:

  • Leflunomide
 
Immunotherapy
Immunosuppressants
Therapeutics that treat rheumatoid arthritis by suppressing the immune system.

Target Products:

  • Hydroxychloroquine Sulfate
 
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Arzerra (Ofatumumab)
 
Neurology
Neurological Disorders
Alzheimer`s Disease
Acetylcholinesterase Inhibitors
Therapeutics that treat Alzheimer's Disease by preventing the breakdown of a the neurotransmitter, acetylcholine.

Target Products:

  • Donepezil Hydrochloride
 
Acetylcholinesterase Inhibitors/Nicotinic Receptor Modulators
Therapeutics that treat Alzheimer's Disease by preventing the breakdown of a the neurotransmitter, acetylcholine, and by modulating the receptor that binds nicotine.

Target Products:

  • Galantamine Hydrobromide
 
N-Methyl-D-Aspartate (NMDA) Receptor Antagonists
Therapeutics that treat the disorders involving the progressive degeneration and death of brain cells by preventing the actions of an amino acid neurotransmitter, N-Methyl-D-Aspartate.

Target Products:

  • Memantine
 
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Therapeutics that treat Alzheimer's Disease by stimulating immune response and regulating inflammation.

Buyer Products:

  • Rosiglitazone XR
 
Epilepsy
Partial Seizures
Complex
Adjunctive Therapy
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid, which prevent nerve activation.

Target Products:

  • Cephalon, Inc. - Gabitril (Tiagabine)
  • Gabapentin
  • Divalproex Sodium Delayed Release Tablets
  • Levetiracetam
 
Potassium Channel Modulators/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid and opening of potassium channels.

Buyer Products:

  • Potiga (Ezogabine)-US/Trobalt (Retigabine)-EU
 
Sodium Channel Blocking Agents
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Buyer Products:

  • Lamictal ODT/EUR-1048 (Lamotrigine)
  • Lamictal (Lamotrigine)

Target Products:

  • Lamotrigine Chewable Tablets
  • Oxcarbazepine
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid as well as blocking the sodium channels which in turn block the conductance of electrical impulses through the brain.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Monotherapy
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid, that prevents nerve activation.

Target Products:

  • Divalproex Sodium Delayed Release Tablets
 
Sodium Channel Blocking Agents
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Buyer Products:

  • Lamictal XR (Lamotrigine)
  • Lamictal (Lamotrigine)

Target Products:

  • Lamotrigine Chewable Tablets
  • Oxcarbazepine
  • Epitol (Carbamazepine)
  • Carbamazepine
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid as well as blocking the sodium channels which in turn block the conductance of electrical impulses through the brain.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Sodium Channel Modulators
Therapeutics that treat complex partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses through the brain.

Target Products:

  • Prompt Phenytoin Sodium
 
Simple
Adjunctive Therapy
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat simple partial seizures by preventing the uptake of gamma-aminobutyric acid which prevents nerve activation.

Target Products:

  • Cephalon, Inc. - Gabitril (Tiagabine)
 
Potassium Channel Modulators/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid and opening of potassium channels.

Buyer Products:

  • Potiga (Ezogabine)-US/Trobalt (Retigabine)-EU
 
Sodium Channel Blocking Agents
Therapeutics that treat Petit Mal Seizures by preventing the entrance of sodium into nerve cells.

Buyer Products:

  • Lamictal (Lamotrigine)
  • Lamictal ODT/EUR-1048 (Lamotrigine)

Target Products:

  • Oxcarbazepine
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Monotherapy
Sodium Channel Blocking Agents
Therapeutics that treat simple partial seizures by blocking the sodium channels which in turn block the conductance of neural impulses.

Buyer Products:

  • Lamictal XR (Lamotrigine)

Target Products:

  • Oxcarbazepine
  • Epitol (Carbamazepine)
  • Carbamazepine
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Primary Generalized Seizures  
Absence (Petit Mal)  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Valproic Acid
  • Divalproex Sodium Delayed Release Tablets
 
Monotherapy  
Calcium Channel Blocking Agents
Therapeutics that treat Petit Mal Seizures by preventing the entrance of calcium into nerve cells.

Target Products:

  • Ethosuximide
 
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Valproic Acid
  • Divalproex Sodium Delayed Release Tablets
 
Tonic-Clonic (Grand Mal)  
Sodium Channel Blocking Agents
Therapeutics that treat Grand Mal Seizures by preventing the entrance of sodium into nerve cells.

Target Products:

  • Epitol (Carbamazepine)
  • Carbamazepine
 
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Sodium Channel Modulators
Therapeutics that treat Grand Mal Seizures by modulating the gates which allow sodium into nerve cells.

Target Products:

  • Prompt Phenytoin Sodium
 
Status Epilepticus  
Sodium Channel Modulators
Therapeutics that treat Status Epilepticus by modulating the portal that allows sodium into the nerve cells.

Target Products:

  • Fosphenytoin Sodium
  • Prompt Phenytoin Sodium
 
Headaches
Chronic  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation by preventing cyclooxygenase activity.

Target Products:

  • Genacote
  • Acetaminophen
  • ASA (Aspirin)
 
Cluster  
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat Cluster Headaches by blocking the receptor that binds with the neurotransmitter, serotonin.

Buyer Products:

  • Imitrex Injection (Sumatriptan Succinate)
 
Tension Type  
Barbiturates/Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Stimulants
Therapeutics that treat tension type headaches by decreasing the excitability of neurons as well as decreasing pain by inhibiting the production of prostaglandins.

Target Products:

  • Butalbital/Aspirin/Caffeine
 
Vascular (Migraine)
Acute Treatments
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Selective Serotonin Receptor Agonists
Therapeutics that treat vascular headaches by inhibiting the action of cyclooxygenase, which is an inflammatory substance, as well as stimulating the serotonin receptor.

Buyer Products:

  • Treximet (Naproxen/Sumatriptan)
 
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat vascular/migraine headaches by stimulating the receptor that binds with the neurotransmitter, serotonin.

Buyer Products:

  • Imitrex Nasal Formulation (Sumatriptan)
  • Imitrex (Sumatriptan Succinate)
  • Amerge (Naratriptan Hydrochloride)
  • Imitrex Injection (Sumatriptan Succinate)

Target Products:

  • Rizatriptan Benzoate
  • Sumatriptan Succinate
Prophylactic Treatments  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that provide preventative treatments for migraine headaches by inhibiting the uptake of molecules that prevent nerve activation.

Target Products:

  • Divalproex Sodium Delayed Release Tablets
 
Selective Serotonin Receptor Agonists (Triptans)
Therapeutics that treat vascular headaches by attaching to specific receptors and mimicking the action of serotonin.

Target Products:

  • Naratriptan Hydrochloride
 
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that prevent migraines by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation, as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate/Barr Labs Topiramate
 
Spasticity (Spinal Shock)  
Alpha Adrenergic Receptor Agonists
Therapeutics that treat spasticity by stimulating the alpha adrenergic receptors.

Target Products:

  • Tizanidine HCl
 
Aspartic Receptor Antagonists/Glutamic Receptor Antagonists
Therapeutics that treat Spinal Shock by blocking the receptors for aspartic acid and glutamic acid, both excitatory neurotransmitters.

Target Products:

  • Baclofen
 
Trigeminal Neuralgia (Tic Douloureux)  
Sodium Channel Blocking Agents
Therapeutics that treat trigeminal Neuralgia by inhibiting the entrance of sodium into the nerve cells.

Target Products:

  • Epitol (Carbamazepine)
  • Carbamazepine
 
Neuromuscular Disorders
Multiple Sclerosis (MS)  
Immunomodulators
Therapeutics that treat multiple sclerosis by changing the actions of the immune system.

Target Products:

  • Copaxone (Glatiramer Acetate)
  • Laquinimod
 
Parkinson`s Disease (PD)
Adjunctive Treatments
Cholinergic Receptor Blocking Agents
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by blocking acetylcholine receptors on neurons.

Target Products:

  • Benztropine Mesylate
 
Dopamine Receptor Agonists
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on neurons.

Buyer Products:

  • IPX066 (Carbidopa/Levodopa Extended Release)

Target Products:

  • Carbidopa/Levodopa
Monoamine Oxidase (MAO) Inhibitors
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by inhibiting the degradation of neurotransmitters.

Target Products:

  • Azilect (Rasagiline Mesylate)
 
Skeletal Muscle Relaxing Agents/Analgesics
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by relaxing motor muscles and relieving pain.

Target Products:

  • Methocarbamol And Aspirin
 
Monotherapy
Dopamine Receptor Agonists
Therapeutics that treat the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on the neurons.

Buyer Products:

  • ReQuip Modutab (Ropinirole Hydrochloride)
  • ReQuip XL (Ropinirole Hydrochloride Extended Release)

Target Products:

  • Pramipexole Dihydrochloride
  • Ropinirole Hydrochloride
Monoamine Oxidase (MAO) Inhibitors
Therapeutics that treat the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by preventing the degradation of neurotransmitters.

Target Products:

  • Azilect (Rasagiline Mesylate)
 
Restless Leg Syndrome
Dopamine Receptor Agonists
Therapeutics that treat Restless Leg Syndrome by stimulating dopamine activity.

Buyer Products:

  • ReQuip Modutab (Ropinirole Hydrochloride)

Target Products:

  • Ropinirole Hydrochloride
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat restless legs syndrome by inhibiting the reuptake of GABA.

Buyer Products:

  • Horizant (Gabapentin Enacarbil Extended Release)/Formerly XP13512/Solzira
 
Tourette`s Syndrome  
Dopamine Receptor Blocking Agents
Therapeutics that treat the disorder involving uncontrolled verbal outbursts, ticks and facial expressions by blocking dopamine receptors on the neurons.

Target Products:

  • Haloperidol
  • Haloperidol Deconate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK2018682 (Sphingosine-1 Phosphate Receptor (S1P))
  • GSK1144814 (NK1/NK3 Antagonist)
  • GSK1034702 (Muscarinic Acetylcholine Agonist)
  • GSK586529 (CRF1 Antagonist)
  • GSK1223249 (NOGO-A Monoclonal Antibody)
  • GSK249320 (Monoclonal Antibody)
  • GSK239512 (Histamine H3 Antagonist)
  • GSK163090 (5HT-1 Antagonist)
  • Rezonic (Casopitant)
  • GSK274150 (Selective iNOS Inhibitor)
  • Firategrast/SB683699
  • PRX-03140 (5-HT4 Serotonin Receptor Agonist)
  • SB-742457 (5HT6 Antagonist)
  • 372475 (5HT/Noradrenaline/Dopamine Reuptake Inhibitor)
  • GSK189254 (Histamine H3 Antagnoist)
  • GSK1018921 (Type 1 Glycine Transport Inhibitor)
  • GSK1014802 (Sodium Channel Inhibitor)
  • GSK933776A (Beta Amyloid Monoclonal Antibody)
  • GSK729327 (AMPA Receptor Modulator)
  • Avandia (Rosiglitazone Maleate)
  • Alzheimer's Disease Vaccine
  • GW876008 (CRF1 Antagonist)
  • SB773812 (Mixed 5HT/Dopaminergic Antagonist)
  • Orvepitant / GW823296 (NK1 Antagonist)
  • SB-649868 (Orexin Antagonist)
  • GSK561679 (CRF1 Antagonist)
  • Losmapimod (p38 Kinase Inhibitor)
  • GSK424887 (NK1 Antagonist/Selective Serotonin Reuptake Inhibitor (SSRI)

Target Products:

  • Cephalon, Inc. - Nuvigil (Armodafinil)
  • Glatiramer Acetate
  • Talampanel
  • TV1102 (Antisense VLA-4 Inhibitor)/Formerly ATL1102
  • Laquinimod
  • Cephalon, Inc. - CEP-26401 (H3 Antagonist)
  • Pagoclone (Gamma Amino Butyric Acid (GABA) Selective Receptor Modulator)
Psychiatric Disorders
Anxiety
Generalized Anxiety Disorder (GAD)
Antihistamines
Therapeutics that treat anxiety by blocking the action of histamines.

Target Products:

  • Hydroxyzine Pamoate
 
Dopamine Receptor Blocking Agents
Therapeutics that treat anxiety by blocking dopamine receptors.

Target Products:

  • Prochlorperazine Maleate
  • Buspirone
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Oxazepam
  • Diazepam
  • Alprazolam/Alprazolam Extended Release
  • Lorazepam
 
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat anxiety by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Target Products:

  • Venlafaxine Hydrochloride Extended Release
  • Venlafaxine Hydrochloride
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat anxiety by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)

Target Products:

  • Paroxetine Hydrochloride
  • Escitalopram Oxalate
Tricyclic Compounds
Therapeutics that treat anxiety by increasing the synaptic concentrations of norepinephrine and serotonin.

Target Products:

  • Doxepin HCl
 
Obsessive Compulsive Disorder (OCD)
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Anxiety by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)

Target Products:

  • Fluvoxamine Maleate
  • Paroxetine Hydrochloride
  • Fluoxetine HCl
  • Sertraline Hydrochloride
Tricyclic Compounds
Therapeutics that treat obsessive compulsive disorder by increasing the synaptic concentrations of norepinephrine and serotonin.

Target Products:

  • Clomipramine HCl Capsules
 
Panic Disorder
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Clonazepam
  • Alprazolam/Alprazolam Extended Release
 
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat panic disorder by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Target Products:

  • Venlafaxine Hydrochloride Extended Release
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat panic disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)
  • Paxil (Paroxetine Hydrochloride)

Target Products:

  • Paroxetine Hydrochloride
  • Sertraline Hydrochloride
Post-Traumatic Stress Disorder (PTSD)
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat post traumatic stress disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil (Paroxetine Hydrochloride)

Target Products:

  • Paroxetine Hydrochloride
  • Sertraline Hydrochloride
Social Anxiety Disorder (SAD)
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Target Products:

  • Venlafaxine Hydrochloride Extended Release
  • Venlafaxine Hydrochloride
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)

Target Products:

  • Sertraline Hydrochloride
Childhood/Adolescent Disorders
Attention Deficit Disorder (ADD)/Attention Deficit Hyperactivity Disorder (ADHD)
Alpha Adrenergic Receptor Agonists
Therapeutics that treat attention deficit disorder (ADD)/attention deficit hyperactivity disorder (ADHD) by stimulating the adrenergic receptors, which cause nervous system stimulation.

Target Products:

  • Intuniv (Guanfacine Extended Release)
 
Dopamine Receptor Blocking Agents
Therapeutics that treat attention deficit disorder by blocking the dopamine receptors.

Target Products:

  • Dexmethylphenidate Hydrochloride
  • Haloperidol Deconate
 
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving hyperactivity in children due to an abnormally short attention span.

Buyer Products:

  • Dexedrine (Dextroamphetamine Sulfate)

Target Products:

  • Dextroamphetamine/Amphetamine
Enuresis (Bedwetting)  
Antidiuretic Agents
Therapeutics that treat enuresis by suppressing the passing of urine.

Target Products:

  • Desmopressin Acetate
 
Eating Disorders  
Bulimia  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat eating disorders by selectively preventing the removal of serotonin.

Target Products:

  • Fluoxetine HCl
 
Mood Disorders
Bipolar Disorders (Manic Depressive Disorders)
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat bipolar disorders by preventing the uptake of gamma-aminobutyric acid, that prevents nerve activation.

Target Products:

  • Divalproex Sodium Delayed Release Tablets
 
Monoaminergic Antagonists
Therapeutics that treat bipolar disorder by blocking the serotonin and dopamine receptors.

Target Products:

  • Quetiapine Fumarate
  • Olanzapine
  • Risperidone Oral Solution
 
Sodium Channel Blocking Agents
Therapeutics that treat bipolar disorders by blocking the sodium channels which in turn prevents the conductance of nerve impulses.

Buyer Products:

  • Lamictal ODT/EUR-1048 (Lamotrigine)
  • Lamictal (Lamotrigine)
 
Tricyclic Compounds
Therapeutics that treat bipolar disorders by increasing the synaptic concentrations of norepinephrine and serotonin.

Target Products:

  • Doxepin HCl
 
Depression
Dopamine Receptor Blocking Agents
Therapeutics that treat depression by blocking the dopamine receptors.

Target Products:

  • Prochlorperazine Maleate
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat depression by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Oxazepam
 
Monoamine Oxidase (MAO) Inhibitors
Therapeutics that treat depression by inhibiting the activity of monoamine oxidase, which degrades neurotransmitters.

Buyer Products:

  • Parnate (Tranylcypromine Sulfate)
 
Monoaminergic Antagonists/Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat depression by selectively preventing the removal of serotonin as well as blocking the serotonin and dopamine receptors.

Target Products:

  • Olanzapine/Fluoxetine
 
Selective Norepinephrine Reuptake Inhibitors (SNRI)
Therapeutics that treat depression by selectively preventing the removal of norepinephrine, and potentiating neurotransmitter activity in the central nervous system (CNS).

Target Products:

  • Venlafaxine Hydrochloride Extended Release
  • Venlafaxine Hydrochloride
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat depression by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)
  • Paxil (Paroxetine Hydrochloride)

Target Products:

  • Citalopram Hydrobromide
  • Trazodone HCl
  • Escitalopram Oxalate
  • Fluoxetine HCl
  • Sertraline Hydrochloride
Serotonin/Norepinephrine Reuptake Inhibitors
Therapeutics that treat depression by inhibiting the neuronal uptake of serotonin and norepinephrine.

Buyer Products:

  • Wellbutrin XL (Bupropion Hydrochloride)
  • Wellbutrin IR/SR (Bupropion Hydrochloride)

Target Products:

  • Nefazodone HCl
  • Bupropion Hydrochloride
  • Bupropion Extended Release
Tetracyclic Compounds
Therapeutics that treat depression by increasing the synaptic concentrations of norepinephrine.

Target Products:

  • Mirtazapine/Mirtazapine Oral Disintegrating Tablets
 
Tricyclic Compounds
Therapeutics that treat depression by increasing the synaptic concentrations of norepinephrine and serotonin.

Target Products:

  • Nortriptyline Hydrochloride
  • Doxepin HCl
 
Premenstrual Dysphoric Disorders
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat premenstrual dysphoric disorders by selectively preventing the removal of serotonin.

Buyer Products:

  • Paxil CR (Paroxetine Hydrochloride)

Target Products:

  • Fluoxetine HCl
  • Sertraline Hydrochloride
Schizophrenia  
Dopamine Receptor Blocking Agents
Therapeutics that treat schizophrenia by blocking the dopamine receptors.

Target Products:

  • Haloperidol
  • Clozapine
  • Haloperidol Deconate
  • Fluphenazine Decanoate
 
Monoaminergic Antagonists
Therapeutics that treat schizophrenia by blocking the serotonin and dopamine receptors.

Target Products:

  • Quetiapine Fumarate
  • Olanzapine
  • Risperidone Oral Solution
 
Sleep Disorders
Excessive Daytime Sleepiness (EDS)  
Alpha Adrenergic Receptor Agonists
Therapeutics that treat excessive daytime sleepiness (EDS) by stimulating the adrenergic receptors, which cause nervous system stimulation.

Target Products:

  • Modafinil
  • Cephalon, Inc. - Provigil (Modafinil)
  • Cephalon, Inc. - Nuvigil (Armodafinil)
  • Armodafinil
 
Insomnia
Antihistamines
Therapeutics that treat insomnia by preventing the functions of histamine on tissues.

Buyer Products:

  • Nytol Quickgels Softgels (Diphenhydramine Hydrochloride)
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat insomnia by enhancing the inhibitory action of gamma-aminobutyric acid.

Buyer Products:

  • LUNIVIA (Eszopiclone)

Target Products:

  • Diazepam
  • Zaleplon
  • Zolpidem Tartrate
  • Estazolam
Orexin Receptor Antagonists
Therapeutics that treat insomnia by inhibiting the action of orexin.

Buyer Products:

  • Almorexant (Orexin Receptor Antagonist)
 
Narcolepsy
Alpha Adrenergic Receptor Agonists
Therapeutics that treat narcolepsy by stimulating the adrenergic receptors, which causes nervous system stimulation.

Target Products:

  • Modafinil
  • Cephalon, Inc. - Provigil (Modafinil)
 
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving chronic and sudden daytime sleepiness.

Buyer Products:

  • Dexedrine (Dextroamphetamine Sulfate)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in very early stages of research where no human subject is involved.

Target Products:

  • Cephalon, Inc. - VEGF Inhibitors
  • BioGeneriX AG Multiple Sclerosis Biologics Program
  • Azilect (Rasagiline Mesylate)
 
Obstetrics/Gynecology
Child Birth/Pregnancy  
Induction/Cervical Ripening  
Oxytocic Agents
Therapeutics that induce contractions by increasing the levels of intracellular calcium in the uterine smooth muscle thus mimicking uterine contractions and transiently impeding uterine blood flow.

Target Products:

  • Oxytocin
 
Prevention (Contraception)  
Contraceptives (Birth Control)  
Estrogens/Progestins
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Target Products:

  • Camrese (levonorgestrel/ethinyl estradiol)
  • SEASONIQUE (levonorgestrel/ethinyl estradiol)
  • Norethindrone/Ethinyl Estradiol/Ferrous Fumarate
  • Drospirenone/Ethinyl Estradiol
  • Previfem (Norgestimate/Ethinyl Estradiol)
  • Tri-Lo Sprintec (Norgestimate/Ethinyl Estradiol)
  • Tri-Previfem (Norgestimate/Ethinyl Estradiol)
 
Progestins
Contraceptive Therapeutics that are female sex hormone necessary for the development of the female reproductive system

Target Products:

  • Plan B One-Step (Levonorgestrel)
  • Medroxyprogesterone Acetate Injection
 
Female Genital Disorders  
Endometrial Hyperplasia  
Progestins
Therapeutics that treat a disorder involving the benign proliferation of cells lining the uterus (endometrium) by increasing progesterone levels in the body.

Target Products:

  • Progesterone Capsules
 
Endometriosis  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat endometriosis by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Leuprolide
 
Infertility  
Hormonal Treatments  
Ovulation Stimulating Agents
Therapeutics that treat infertility by stimulating the ovaries to release a mature egg.

Target Products:

  • XM17/Follitropin Alpha (Gonal-f Biosimilar Product)
 
Progestins
Therapeutics that treat female disorders characterized by the inability to achieve pregnancy or carry a pregnancy to term by increasing progesterone level in the body to induce uteran conditions favorable to conception and pregnancy.

Target Products:

  • Progesterone Vaginal Ring (DR-201)
 
Ovarian  
Abnormal Puberty  
Precocious  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat abnormal puberty by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Leuprolide
 
Vulvovaginal  
Atrophy  
Hormonal Treatments  
Estrogens/Progestins
Therapeutics that treat disorders characterized by thinning of the vaginal walls with a combination of the female sex hormones estrogen and progestin.

Target Products:

  • Estradiol/Norethindrone Acetate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of female reproductive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Retosiban / GSK221149 (Oxytocin Antagonist)
 
Oncology
Breast Cancer
Localized  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage breast cancers by interacting with DNA and inhibiting cell division.

Target Products:

  • Thiotepa
 
Aromatase Inhibitors
Therapeutics that treat and manage breast cancer by interfering with estrogen production in peripheral tissues.

Target Products:

  • Anastrozole
 
Estrogen Receptor Blocking Agents
Therapeutics that treat and manage breast cancers by blocking the uptake of estrogen which has been implicated in causing breast cancer.

Target Products:

  • Tamoxifen Citrate
 
Estrogen Synthesis Inhibitors
Therapeutics that treat and manage breast cancers by inhibiting the conversion of adrenal androgens to estrogen in peripheral tissues.

Target Products:

  • Letrozole
 
Topoisomerase II Inhibitors
Therapeutics that treat breast cancer by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage breast cancers that have spread beyond their original tumor site by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Estrogen Receptor Blocking Agents
Therapeutics that treat and manage breast cancer by blocking the uptake of estrogen which has been implicated in causing breast cancer.

Target Products:

  • Tamoxifen Citrate
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers of the breast that have spread beyond their original tumor site by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Epirubicin HCL
 
Tyrosine Kinase Inhibitors
Therapeutics that treat breast cancer by inhibiting the action of tyrosine kinase, enzymes that play a vital role in cell division.

Buyer Products:

  • Votrient/Formerly Armala (Pazopanib)
  • Tykerb (Lapatinib Ditosylate)
  • Votrient (Pazopanib) + Tyverb/Tykerb
 
Dermatology
Malignant Melanoma
Alkylating Agents  
Carbazines
Therapeutics that treat Malignant Melanoma by inhibiting RNA and DNA synthesis through the formation of carbonium ions.

Target Products:

  • Dacarbazine
 
Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase (MEK) Inhibitors
Therapeutics that stop the growth of cancer cells by blocking some of the enzymes necessary for cancer cell growth.

Buyer Products:

  • GSK1120212 (MEK Inhibitor)
 
Raf Kinase Inhibitors
Therapeutics that treat skin cancer by interrupting the signaling pathways that are responsible for tumor cell proliferation.

Buyer Products:

  • GSK2118436 (BRaf Protein Kinase Inhibitor)
 
Reactive Oxygen Species (ROS) Inducers
Therapeutics that treat skin cancer by inducing oxidative stress inside tumor cells and triggering programmed cell death.

Buyer Products:

  • Elesclomol/Formerly STA-4783
 
Vaccines
Therapeutics that are meant to promote an immune response against a patient's melanoma.

Buyer Products:

  • MAGE-A3 ASCI (Cancer Vaccine)
 
Squamous Cell Carcinoma  
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat cancers of keratinizing epidermal cells by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Digestive System
Colon Cancer/Colorectal Cancer  
Metastatic  
Alkylating Agents  
Platinum-Based Agents
Platinum containing therapeutics that are meant to treat and manage colorectal cancers that have spread beyond their original tumor site by interacting with DNA to inhibit cell division.

Target Products:

  • Oxaliplatin
 
Topoisomerase I Inhibitors
Therapeutics that treat and manage colorectal cancers by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Irinotecan Hydrochloride
 
Palliative Agents  
Folic Acid Derivatives
Therapeutics that treat colorectal cancers by helping to reduce toxicity by allowing DNA/RNA/Protein synthesis to occur even when the pathway has been blocked by folic acid antagonists.

Target Products:

  • Leucovorin Calcium
 
Gastric Cancer (Stomach Cancer)
Localized  
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers of the stomach by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Metastatic  
Tyrosine Kinase Inhibitors
Therapeutics that treat gastric cancer by inhibiting the action of tyrosine kinase, compounds that play a vital role in cell division.

Buyer Products:

  • Tykerb (Lapatinib Ditosylate)
 
Pancreatic Cancer  
Localized  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage primary tumors of the pancreas by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Metastatic  
Alkylating Agents  
Nitrosoureas
Therapeutics that can cross the blood-brain barrier to treat and manage pancreatic cancers by interacting with DNA and inhibiting cell division.

Target Products:

  • Zanosar (Streptozocin)
 
Platinum-Based Agents
Platinum containing therapeutics that are meant to treat and manage pancreatic cancers that have spread beyond their original tumor site by interacting with DNA to inhibit cell division.

Target Products:

  • Oxaliplatin
 
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage metastatic pancreatic cancer by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Endocrinology  
Carcinoid Tumors  
Palliative Agents  
Somatostatin Analogs
Therapeutics that treat and manage a serotonin secreting neoplasm known as a carcinoid tumor by inhibiting the secretion of growth hormone which allows the tumor to grow rapidly.

Target Products:

  • Octreotide Acetate
 
Parathyroid Gland  
Palliative Agents  
Calcimimetic Agents
Therapeutics that treat hypercalcemia (elevated calcium levels in the blood) by decreasing parathyroid hormone levels.

Target Products:

  • Cinacalcet
 
Thyroid Gland  
Localized  
Topoisomerase II Inhibitors
Therapeutics that treat and manage primary tumors of the thyroid gland by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Head/Neck Cancer
Localized
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat primary tumors of the head and neck by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage primary tumors of the head and neck by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Buyer Products:

  • Tykerb (Lapatinib Ditosylate)
 
Hematology
Leukemia (White Blood Cell Cancer)
Lymphoid
Acute
Lymphoblastic
Antimetabolite Agents
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers of immature lymphocytic cells by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Arranon (Nelarabine)

Target Products:

  • Purinethol (Mercaptopurine)
Antimicrotubule Agents
Therapeutics that treat and manage rapidly progressing cancers of immature lymphocytic cells by blocking the normal function of microtubules, thus inhibiting cell division.

Target Products:

  • Vincasar PFS (Vincristine Sulfate Injection)
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers of lymphocytic cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Lymphocytic  
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers of immature lymphocytic cells by interfering with nucleic acid biosynthesis.

Target Products:

  • Purinethol (Mercaptopurine)
 
Topoisomerase II Inhibitors
Therapeutics isolated principally from microorganisms that treat rapidly progressing cancers of lymphocytic cells by interacting with DNA.

Target Products:

  • Idarubicin
  • Daunoru CIII (Daunorubicin)
 
Chronic
Lymphocytic (CLL)
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage slowly progressing cancers of lymphocytic cells by interacting with DNA and inhibiting cell division.

Target Products:

  • Cephalon, Inc. - Treanda (Bendamustine Hydrochloride)
 
Antimetabolite Agents  
Adenosine Deaminase Inhibitors
Therapeutics that treat and manage slowly progressing cancers of lymphocytic cells by inhibiting the transformation of deoxyadenosine into deoxyinosine thereby impairing DNA synthesis as well as leaving the cancer cells unable to repair single stranded DNA breaks.

Target Products:

  • Fludarabine Phosphate
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of leukemia cells and thereby induce their death.

Buyer Products:

  • Arzerra (Ofatumumab)
 
Myeloid
Acute
Erythroleukemic  
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers affecting immature red blood cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Mitoxantrone Hydrochloride
  • Daunoru CIII (Daunorubicin)
 
Monocytic  
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers affecting mononuclear cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Mitoxantrone Hydrochloride
  • Daunoru CIII (Daunorubicin)
 
Myeloblastic
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers affecting immature cells of the bone marrow by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Tabloid (Thioguanine)
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers affecting immature cells of the bone marrow by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Mitoxantrone Hydrochloride
  • Doxorubicin HCl
 
Myelogenous (AML)
Antimetabolite Agents
Purine Analogs
Therapeutics that treat and manage rapidly progressing cancers of the myelogenous cellsby interfering with nucleic acid biosynthesis.

Buyer Products:

  • Tabloid (Thioguanine)
 
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage rapidly progressing cancers of the myelogenous cells by inhibiting the production of DNA.

Target Products:

  • Cytosar-U (Cytarabine)
 
Antimicrotubule Agents
Therapeutics that treat and manage rapidly progressing cancers of myelogenous cells by blocking the normal function of microtubules, thus inhibiting cell division.

Target Products:

  • Vincasar PFS (Vincristine Sulfate Injection)
 
Stem Cell Therapy
Adult stem cells obtained from adult patients to treat hematological cancers.

Target Products:

  • StemEx (Cord Blood Stem/Progenitor Cells)
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage rapidly progressing cancers of the myelogenous cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Idarubicin
  • Mitoxantrone Hydrochloride
  • Daunoru CIII (Daunorubicin)
 
Promyelocytic (APL)  
DNA Fragmenting Agents
Therapeutics that treat leukemia by breaking DNA, resulting in the death of cancer cells.

Target Products:

  • Cephalon, Inc. - Trisenox (Arsenic Trioxide)
  • Arsenic Trioxide
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage promyelocytic leukemia by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Mitoxantrone Hydrochloride
 
Chronic  
Myeloblastic  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage cancers of immature myeloid cells by inhibiting the production of DNA.

Target Products:

  • Cytosar-U (Cytarabine)
 
Myelogenous (CML)  
Mcl-1 Inhibitors
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by inhibiting Mcl-1 protein synthesis, leading to cancer cell death (apoptosis).

Target Products:

  • Omapro (Omacetaxine Mepesuccinate)/Formerly Ceflatonin
 
Stem Cell Therapy
Adult stem cells obtained from adult patients to treat hematological cancers.

Target Products:

  • StemEx (Cord Blood Stem/Progenitor Cells)
 
Palliative Agents  
Alkylating Agents  
Alkylsulfonates
Therapeutics that treat and manage cancers of myeliod cells by cross-linking and breaking DNA strands which ultimately leads to cell death.

Buyer Products:

  • Myleran (Busulfan)
 
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancers of myeliod cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
 
Lymphoma (Lymphatic Cancer)
Hodgkin`s Disease
Alkylating Agents  
Carbazines
Therapeutics that treat Hodgkin's Disease by inhibiting RNA and DNA synthesis through the formation of carbonium ions.

Target Products:

  • Dacarbazine
 
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat lymphoma characterized by the presence of Reed-Sternberg cells by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Palliative Agents  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage lymphoma characterized by the presence of Reed-Sternberg cells by interacting with DNA and inhibiting cell division but that are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
 
Stem Cell Therapy
Adult stem cells obtained from adult patients to treat hematological cancers.

Target Products:

  • StemEx (Cord Blood Stem/Progenitor Cells)
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage lymphoma characterized by the presence of Reed-Sternberg cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Non-Hodgkin`s Lymphoma (NHL)
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage lymphomas of B-cells and T-cells by interacting with DNA and inhibiting cell division.

Target Products:

  • Cephalon, Inc. - Treanda (Bendamustine Hydrochloride)
 
Antimetabolite Agents  
Purine Analogs
Therapeutics that treat and manage lymphomas of B-cells and T-cells by interfering with nucleic acid biosynthesis.

Buyer Products:

  • Arranon (Nelarabine)
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of lymphoma cells and thereby induce their death.

Buyer Products:

  • Arzerra (Ofatumumab)
 
Palliative Agents
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage lymphomas of B-cells and T-cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Leukeran (Chlorambucil)
 
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat lymphomas of B-cells and T-cells by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Radioactive Agents/Monoclonal Antibodies
Therapeutics that utilize a monoclonal antibody to target a local dose of radiation to lymphoma cells in order to induce their death.

Buyer Products:

  • Bexxar (Iodine I-131/Tositumomab)
 
Stem Cell Therapy
Adult stem cells obtained from adult patients to treat hematological cancers.

Target Products:

  • StemEx (Cord Blood Stem/Progenitor Cells)
 
Multiple Myeloma (Plasma Cell Cancer)  
Palliative Agents  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancers of mature antibody producing white blood cells by interacting with DNA and inhibiting cell division but are not curative.

Buyer Products:

  • Alkeran (Melphalan Hydrochloride)
 
Musculoskeletal System
Bone Cancer  
Osteosarcoma  
Palliative Agents  
Folic Acid Derivatives
Therapeutics that are meant to reduce the toxicity of treating malignant tumors of the bone by allowing DNA/RNA/Protein synthesis to occur even when the pathway has been blocked by folic acid antagonists.

Target Products:

  • Leucovorin Calcium
 
Metastatic
Osteolytic Bone Metastases  
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat and manage bone cancers that have spread beyond their original tumor site by preventing the loss of bone mass followed by deposition of new bone which can result in entrapped tumors below the new bone surface.

Target Products:

  • Pamidronate Disodium
 
Receptor Activator Of Nuclear Factor-kB Ligand (RANKL) Inhibitors
Therapeutics that treat cancer bone metastases by inhibiting a mediator of osteoclast formation resulting in suppression of bone resorption.

Buyer Products:

  • XGEVA (Denosumab)
 
Rhabdomyosarcoma  
Angiogenesis Inhibitors
Therapeutics that treat rhabdomyosarcomas by inhibiting the growth of blood vessels around malignant growths, effectively cutting off the blood/nutrient supply.

Buyer Products:

  • Votrient/Formerly Armala (Pazopanib)
 
Neurology  
Brain Cancer  
Neuroblastoma  
Topoisomerase II Inhibitors
Therapeutics that treat a and manage cancer of primitive ganglion cells by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • Arzerra (Ofatumumab)
  • Votrient / Formerly Armala (Pazopanib) Oral
  • GSK1363089 (Foretinib) (Mesenchymal-Epithelial Transition Factor (C-Met) Kinase Inhibitor)
  • WT1
  • GSK1120212 (MEK Inhibitor)
  • XGEVA (Denosumab)
  • GSK1120212/BKM120 Combination
  • GSK2256098 (Focal Adhesion Kinase Inhibitor)
  • GSK1120212/GSK2118436 Combination
  • PRAME
  • NY ESO-1
  • GSK2141795 (AKT Protein Kinase Inhibitor)
  • GSK2110183 (AKT Protein Kinase Inhibitor)
  • GSK2126458 (Pi3 Kinase Inhibitor)
  • 184072 (SIRT1 Activator)
  • Votrient/Formerly Armala (Pazopanib)
  • Iboctadekin/Rituximab Combination Therapy
  • Dutasteride/Testosterone
  • GSK461364 (Polo-Like Kinase Inhibitor)
  • Cervarix (HPV16/HPV18 Vaccine)
  • XL880/1363089 (VEGFR/Met Inhibitor)
  • 2401502 (Domain Antibody Targetted Multi-Component Vaccine)
  • Iboctadekin/Doxil Combination Therapy (IL18 Immunomodulator/Topoisomerase II Inhibitor)

Target Products:

  • Quinamed (Amonafide Dihydrochloride)
  • Omapro (Omacetaxine Mepesuccinate)/Formerly Ceflatonin
  • Cephalon, Inc. - Trisenox (Arsenic Trioxide)
  • Cephalon, Inc. - Treanda (Bendamustine Hydrochloride)
  • Cephalon, Inc. - Gemin X - Teglarinad (NAD+ Synthesis Inhibitor)/Formerly GMX1777
  • Cephalon, Inc. - Gemin X - Obatoclax (Pan Bcl-2 Inhibitor)/Formerly GX15-070
  • CT-011
  • Talampanel
  • StemEx (Cord Blood Stem/Progenitor Cells)
  • Custirsen/Formerly OGX-011
  • Cephalon, Inc. - CEP-18770 (Proteasome Inhibitor)
  • Cephalon, Inc. - CEP-11981 (VEGF-R/TIE2 Kinase Inhibitor)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Buyer Products:

  • OP-R003 (Human Anti-Interleukin-6 Antibody)
  • OMP-21M18 (Monoclonal Antibody)

Target Products:

  • CXS-6001 (Antimicrotubule Agent)
  • CXS-273
  • CXS-2101 (NF-Kappa B Inhibitor)
  • Cephalon, Inc. - VEGF Inhibitors
  • Cephalon, Inc. - Tie-2 Kinase Receptor Inhibitor
  • Cephalon, Inc. - Proteasome Inhibitors
  • Cephalon, Inc. - Mesoblast Mesenchymal Precursor Cells
  • Cephalon, Inc. - Gemin X - Telomere Capping Program
  • Cephalon, Inc. - CEP-37440 (ALK/FAK Kinase Inhibitor)
  • Cephalon, Inc. - CEP-37250/KHK2804 (Targets Glycolipids)
  • Cephalon, Inc. - CEP 32496 (B-Raf Inhibitor)
Respiratory System/Thoracic
Lung Cancer
Non Small Cell Lung Cancer (NSCLC)
Angiogenesis Inhibitors
Therapeutics that inhibit the growth of blood vessels around cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma, effectively cutting off the blood/nutrient supply.

Buyer Products:

  • Votrient/Formerly Armala (Pazopanib)
 
Antimicrotubule Agents
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the normal function of microtubules, thus inhibiting cell division.

Buyer Products:

  • Navelbine (Vinorelbine Tartrate)

Target Products:

  • Vinorelbine Tartrate
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Vaccines
Therapeutics that are meant to promote an immune response against a patient's non-small cell lung cancer (NSCLC).

Buyer Products:

  • MAGE-A3 ASCI (Cancer Vaccine)
 
Small Cell Lung Cancer (SCLC)  
Topoisomerase I Inhibitors
Therapeutics that treat and manage cancers of the small cells in the lung by inhibiting a specific enzyme, topoisomerase I, which is needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin I.V. (Topotecan Hydrochloride)
  • Hycamtin Oral (Topotecan Hydrochloride)
 
Urology
Cervical Cancer
Localized
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat primary malignant tumors of the cervix by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Papillomavirus Vaccines
Therapeutics that are meant to promote an immune response against the Papillomavirus that are involved in the pathogenesis of cervical cancer.

Buyer Products:

  • Cervarix (HPV16/HPV18 Vaccine)
 
Topoisomerase I Inhibitors
Therapeutics that treat and manage cancers of the cervix by inhibiting a specific enzyme, topoisomerase I, which is needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin I.V. (Topotecan Hydrochloride)
 
Kidney Cancer (Renal Cell Carcinoma)
Localized  
Angiogenesis Inhibitors
Therapeutics that treat localized renal cell carcinomas by inhibiting the growth of blood vessels around malignant growths, effectively cutting off the blood/nutrient supply.

Buyer Products:

  • Votrient/Formerly Armala (Pazopanib)
 
Wilm`s Tumor (Nephroblastoma)  
Topoisomerase II Inhibitors
Therapeutics that treat and manage tumors of the kidney by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Ovarian Cancer
Adenocarcinoma
Alkylating Agents
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage cancer of cells lining the ovary by interacting with DNA and inhibiting cell division.

Buyer Products:

  • Alkeran (Melphalan Hydrochloride)

Target Products:

  • Thiotepa
Platinum-Based Agents
Platinum containing therapeutics that treat and manage cancer of cells lining the ovary by interacting with DNA and inhibiting cell division.

Target Products:

  • Carboplatin
 
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage ovarian cancer by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancer of cells lining the ovary by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Germ Cell Tumors  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage ovarian cancer by inhibiting the production of DNA.

Target Products:

  • Gemcitabine Injection
 
Metastatic
Alkylating Agents  
Platinum-Based Agents
Platinum containing therapeutics that treat and manage ovarian cancers that have spread beyond their original tumor site by interacting with DNA and inhibiting cell division.

Target Products:

  • Cisplatin
 
Topoisomerase I Inhibitors
Therapeutics that treat and manage ovarian cancers that have spread beyond their original tumor site by inhibiting a specific enzyme, topoisomerase I, needed for transcription and replication of DNA.

Buyer Products:

  • Hycamtin I.V. (Topotecan Hydrochloride)
 
Palliative Agents  
Alkylating Agents  
Platinum-Based Agents
Platinum containing therapeutics that treat and manage ovarian cancers by interacting with DNA and inhibiting cell division but are not curative.

Target Products:

  • Carboplatin
 
Penile Cancer  
Squamous Cell Carcinoma  
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat cancer of the squamous cells of the penis by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Prostate Cancer
Localized
5-Alpha Reductase Inhibitors
Therapeutics that treat prostate cancer by inhibiting the formation of Dihydrotestosterone from testosterone.

Buyer Products:

  • Avodart (Dutasteride)
 
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat and manage prostate cancer by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Leuprolide
 
Metastatic
Androgen Receptor Blockers
Therapeutics that treat and manage prostate cancers that have spread beyond their original tumor site by binding to the androgen receptors in target tissue thus inhibiting the action of androgens.

Target Products:

  • Flutamide
  • Bicalutamide
 
Antisense Agents
Therapeutics that treat metastatic prostate cancer by targeting specific messenger-RNA and thereby inhibiting the production of specific proteins.

Target Products:

  • Custirsen/Formerly OGX-011
 
Receptor Activator Of Nuclear Factor-kB Ligand (RANKL) Inhibitors
Therapeutics that treat cancer bone metastases by inhibiting a mediator of osteoclast formation resulting in suppression of bone resorption.

Buyer Products:

  • XGEVA (Denosumab)
 
Palliative Agents  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat and manage prostate cancer by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations but are not curative.

Target Products:

  • Leuprolide
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancer of the prostate gland by inhibiting a specific enzyme needed for transcription and replication of DNA but are not curative.

Target Products:

  • Mitoxantrone Hydrochloride
 
Testicular Cancer  
Localized  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage primary tumors of the testes by interacting with DNA and inhibiting cell division.

Target Products:

  • Ifosfamide
 
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat primary tumors of the testes by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Metastatic  
Alkylating Agents  
Platinum-Based Agents
Platinum containing therapeutics that treat and manage testicular cancers that have spread beyond their original tumor site by interacting with DNA and inhibiting cell division.

Target Products:

  • Cisplatin
 
Urinary Bladder Cancer  
Papillocarcinoma  
Alkylating Agents  
Nitrogen Mustard Type
Therapeutics derived from mustard gas that treat and manage mushroom shaped tumors that arise from the inner lining of the bladder by interacting with DNA and inhibiting cell division.

Target Products:

  • Thiotepa
 
Transitional Cell Carcinoma  
Alkylating Agents  
Platinum-Based Agents
Platinum containing therapeutics that treat and manage cancers arising from the lining of the bladder by interacting with DNA and inhibiting cell division.

Target Products:

  • Cisplatin
 
Topoisomerase II Inhibitors
Therapeutics that treat and manage cancers arising from the lining of the bladder by inhibiting a specific enzyme needed for transcription and replication of DNA.

Target Products:

  • Doxorubicin HCl
 
Vulvar Cancer  
Squamous Cell Carcinoma  
Antitumor Antibiotics
Therapeutics isolated principally from microorganisms that treat and manage cancers that arise from skin cells of the external female genitalia by interacting with DNA.

Target Products:

  • Bleomycin Sulfate
 
Ophthalmology
Degenerative Disorders  
Glaucoma  
Alpha Adrenergic Receptor Agonists
Therapeutics that decrease the formation and increase the outflow of the fluid of the eye.

Target Products:

  • Brimonidine Tartrate
 
Carbonic Anhydrase Inhibitors
Therapeutics that decrease the formation of the fluid of the eye.

Target Products:

  • Dorzolamide HCl Ophthalmic Solution
  • Methazolamide
 
Irritation/Inflammation  
Antibacterial Agents (Antibiotics)
Therapeutics that treat infections by inhibiting bacterial replication.

Target Products:

  • Neomycin Sulfate
 
Ocular Hypertension  
Alpha Adrenergic Receptor Agonists
Therapeutics that decrease the formation and increase the outflow of the fluid of the eye.

Target Products:

  • Brimonidine Tartrate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of eye disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Votrient / Formerly Armala (Pazopanib) Oral
  • Votrient / Formerly Armala (Pazopanib) (Eye Drops)
 
Pain Management
Anesthesia  
General (Systemic)  
Adjunctive  
Acetylcholine Blocking Agents
Therapeutics that inhibit neuromuscular activity by competing with acetylcholine at the cholinergic receptors resulting in neuromuscular blockage.

Target Products:

  • Teva Parenteral Rocuronium Bromide
  • Vecuronium Bromide
  • Pancuronium Bromide
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that result in anesthesia by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Diazepam
 
Hypnotic Agents (Sedatives)
Therapeutics that result in anesthesia by inducing sleep. These therapeutics have no analgesic action.

Target Products:

  • Propofol
 
Primary  
Hypnotic Agents (Sedatives)
Therapeutics that result in anesthesia by inducing sleep. These therapeutics have no analgesic action.

Target Products:

  • Propofol
 
Reversal  
Gamma-Aminobutyric Acid (GABA) Receptor Antagonists
Therapeutics that reverse general anesthesia by competitively inhibiting benzodiapizines at the GABA receptors, thus reducing their effect and reversing the anesthesia.

Target Products:

  • Flumazenil
 
Local  
Sodium Channel Blocking Agents
Therapeutics that treat pain by blocking the movement of sodium ions and thus the initiation and conduction of nerve impulses across the neuronal membrane.

Target Products:

  • Lidocaine Hydrochloride
 
Narcotics  
Analgesics/Opioids
Therapeutics that treat pain by binding to certain nervous system receptors which alters the both the perception of pain as well as the emotional response to pain.

Target Products:

  • Propoxyphene Napsylate/Acetaminophen
  • Acetaminophen/Codeine Phosphate
  • Acetaminophen/Tramadol Hydrochloride
  • Hydrocodone Bitartrate/Ibuprofen
 
Opioids
Therapeutics that treat pain by binding to certain nervous system receptors which alter both the perception of pain as well as the emotional response to pain.

Target Products:

  • Cephalon, Inc. - Tamper-Deterrent Hydrocodone Bitartrate Extended Release Tablets/Formerly CEP 33237
  • Cephalon, Inc. - Generic OTFC (Oral Transmucosal Fentanyl Citrate)
  • Fentanyl Transdermal System
  • Cephalon, Inc. - Fentora (Fentanyl Buccal Tablet)
  • Tramadol HCl
  • Propoxyphene HCl
  • Cephalon, Inc. - Actiq Sugar-Free (Oral Transmucosal Fentanyl Citrate) [C-II]
 
Non-Narcotics
Analgesics Combinations  
Analgesics/Antipyretics
Therapeutics that treat pain and fever by inhibiting the action of prostaglandins.

Target Products:

  • Genaced (Acetominophen/Caffine/Aspirin)
 
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat pain by inhibiting the reuptake of GABA, which increases the levels of GABA in the synapses.

Buyer Products:

  • Horizant (Gabapentin Enacarbil Extended Release)/Formerly XP13512/Solzira

Target Products:

  • Gabapentin
Non-Steroidal Anti-Inflammatory Drugs (NSAID)
Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
Therapeutics that treat pain by specifically inhibiting the action of cyclooxygenase-2.

Target Products:

  • Cephalon, Inc. - CEP-33222/AI-525 (Intravenous Celecoxib)
  • Meloxicam
 
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Stanback (Aspirin)

Target Products:

  • Genacote
  • Fenoprofen Calcium
  • Acetaminophen
  • Diflunisal
  • Diclofenac Potassium
  • Ketorolac Tromethamine
  • Ketoprofen
  • Flurbiprofen
  • Etodolac
  • ASA (Aspirin)
Skeletal Muscle Relaxing Agents
Therapeutics that treat pain by depressing specific synaptic reflexes preferentially.

Target Products:

  • Cyclobenzaprine
  • Chlorzoxazone
 
Skeletal Muscle Relaxing Agents/Analgesics
Therapeutics that treat pain by depressing specific synaptic reflexes preferentially, as well as prevent inflammation by inhibiting the action of prostaglandins.

Target Products:

  • Methocarbamol And Aspirin
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat pain by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Target Products:

  • Prednisone
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of pain in early stages of clinical research where human subject is involved.

Buyer Products:

  • 681323 (p38 Kinase Inhibitor)
  • Losmapimod (p38 Kinase Inhibitor)
  • Horizant (Gabapentin Enacarbil Extended Release)/Formerly XP13512/Solzira
  • GW842166 (Non-Cannabinoid CB2 Agonist)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of pain in very early stages of research where no human subject is involved.

Target Products:

  • Cephalon, Inc. - CEP-37247 (Tumor Necrosis Factor-Alpha Blocker)
 
Respiratory System
Lower Respiratory Tract Disorders (Lung Disorders)
Asthma
Acute Treatments
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that dilate the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine, and counteract or suppress inflammation using a steroidal compound.

Buyer Products:

  • Relovair (Fluticasone Furoate/Vilanterol Trifenatate)
 
Bronchodilators
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Serevent (Salmetrol Xinafoate)
  • Non-CFC Ventolin (Albuterol)

Target Products:

  • Albuterol Spiromax
  • Easi-Breathe Albuterol CFC-Free Inhaler
  • Proair HFA (Albuterol Sulfate Inhalation Aerosol)
  • Albuterol Sulfate
  • Terbutaline Sulfate
Prophylactic Treatments
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat asthma by reducing inflammation in the lungs with steroids and that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Advair HFA Inhalation Aerosol (Fluticasone Propionate/Salmeterol)
  • Advair Diskus (Salmeterol/Fluticasone)
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that treat asthma by reducing inflammation in the lung passages with steroids.

Buyer Products:

  • Flovent HFA Inhalation Aerosol (Inhaled Fluticasone Propionate HFA)

Target Products:

  • Budesonide Formoterol Spiromax
  • QVAR (Beclomathasone Dipropionate HFA)
  • Budesonide Respules
Bronchitis
Acute Treatments
Bronchodilators
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Non-CFC Ventolin (Albuterol)

Target Products:

  • Easi-Breathe Albuterol CFC-Free Inhaler
  • Proair HFA (Albuterol Sulfate Inhalation Aerosol)
  • Albuterol Sulfate
  • Terbutaline Sulfate
Complications  
Bacterial Infections  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Target Products:

  • Sulfamethoxazole/Trimethoprim
 
Bronchospasm
Bronchodilators
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Serevent (Salmetrol Xinafoate)
  • Non-CFC Ventolin (Albuterol)

Target Products:

  • Easi-Breathe Albuterol CFC-Free Inhaler
  • Proair HFA (Albuterol Sulfate Inhalation Aerosol)
  • Albuterol Sulfate
  • Terbutaline Sulfate
Chronic Obstructive Pulmonary Disease (COPD)
Acute Treatments
Beta Adrenergic Receptor Agonists/Muscarinic Receptor Antagonists
Therapeutics that cause dilation of the lung passages through dual action of supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine, and by blocking the action of choline and other cholinergic agents by binding to the muscarinic receptor.

Buyer Products:

  • GSK573719/Vilanterol Combination (Long Acting Muscarninic Agonist/Long Acting Beta Agonist)
 
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that dilate the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine, and counteract or suppress inflammation using a steroidal compound.

Buyer Products:

  • Relovair (Fluticasone Furoate/Vilanterol Trifenatate)
 
Bronchodilators
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Buyer Products:

  • Vilanterol/642444
  • Non-CFC Ventolin (Albuterol)
  • Serevent (Salmetrol Xinafoate)

Target Products:

  • Albuterol Spiromax
  • Easi-Breathe Albuterol CFC-Free Inhaler
  • Proair HFA (Albuterol Sulfate Inhalation Aerosol)
  • Albuterol Sulfate
Beta Adrenergic Receptor Agonists/Anticholinergic Agents
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine and by inhibiting the action of acetylcholine on post-ganglionic nerves as well as smooth muscle.

Target Products:

  • Albuterol Sulfate/Ipratropium Bromide Inhalation Solution
 
Muscarinic Receptor Antagonists
Therapeutics that treat the by blocking the action of choline and other cholinergic agents by binding to the muscarinic receptor.

Buyer Products:

  • GSK573719 (Muscarinic Acetylcholine Antagonist)
 
Prophylactic Treatments  
Beta Adrenergic Receptor Agonists/Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that are used to prevent COPD attacks by preventing inflammation and stimulating beta adrenergic receptors.

Buyer Products:

  • Advair Diskus (Salmeterol/Fluticasone)
 
Emphysema  
Acute Treatments  
Bronchodilators  
Beta Adrenergic Receptor Agonists
Therapeutics that cause dilation of the lung passages by supporting the actions of the adrenergic transmitters like epinephrine and norepinephrine.

Target Products:

  • Terbutaline Sulfate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • 159802 (Long-Acting Beta2 Agonist)
  • 1440115 (Urotensin Antagonist)
  • GW685698 (Glucocorticoid Agonist)
  • GSK159797 (Long-Acting Beta 2 Agonist)
  • GSK2245840 / SRT2104 (SIRT1 Activator)
  • GSK610677 (Inhaled P38 Kinase Inhibitor)
  • Losmapimod (p38 Kinase Inhibitor)
  • SB-705498 (Transient Receptor Potential Vanilloid (TRPV1) Antagonist)
  • GSK2190915 (5-Lipoxygenase-Activating Protein (FLAP) Inhibitor)
  • APN01 (Recombinant Human Angiotensin Converting Enzyme 2)
  • GSK1160724 (Inhaled Long-Acting Muscarinic Antagonist)
  • Bosatria (Mepolizumab)
  • GSK1325756 (Chemokine Receptor (CXCR2) Antagonist)
  • GSK233705 (Darotropium)
  • GSK961081 (Muscarinic Antagonist/Beta2 Agonist)
  • 870086 (Glucocorticoid Agonist)
  • 256066 (PDE 4 Inhibitor)
  • 681323 (p38 Kinase Inhibitor)
  • GSK679586A (Monoclonal Antibody)
  • SB656933 (Chemokine Receptor (CXCR2) Antagonist)

Target Products:

  • Budesonide Formoterol Spiromax
  • Cephalon, Inc. - Cinquil (Reslizumab)
Upper Respiratory Tract Disorders
Coughs/Colds
Anticholinergic Agents
Therapeutics that block the actions of choline and other cholinergic agents.

Target Products:

  • Ipratropium
 
Anticholinergic Agents/Opioids
Therapeutics that treat coughs and colds by relieving pain and fever as well as suppressing cough.

Buyer Products:

  • Contac Cough & Sore Throat (Dextromethorphan Hydrobromide/Acetaminophen)
 
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Buyer Products:

  • Contac 12 Hour Allergy (Clemastine Fumarate)

Target Products:

  • Fexofenadine Hydrochloride
  • Cetirizine Hydrochloride
  • Promethazine Hydrochloride
  • Genahist (Diphenhydramine HCl)
  • Clemastine Fumarate
  • Diphenhydramine HCl
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Cyproheptadine HCl
 
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and reduces the amount of mucous build up.

Target Products:

  • Genac (Triprolidine/Pseudoephedrine HCl)
 
Antihistamines/Decongestants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by suppressing inflammation, reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Severe Cold And Flu Caplets Maximum Strength (Phenylpropanolamine HCl/Chlropheniramine Maleate/ Acetaminophen/ Dextromethorphan Hydrobromide)
  • Contac Allergy/Sinus Night Capsules (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Acetaminophen)
 
Antihistamines/Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by suppressing inflammation, reducing mucous build up, relieving or preventing coughs, relieving pain, and reducing fever.

Buyer Products:

  • Contac Night Cold & Flu Caplets (Diphenhydramine Hydrochloride/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Severe Cold & Flu Hot Medicine (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Severe Cold Formula Night Strength (Doxylamine Succinate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen/Alcohol)
  • Contac Severe Cold Formula Capsules (Chlorpheniramine Maleate/Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
 
Decongestants
Therapeutics that treat coughs and colds by reducing mucous build up.

Target Products:

  • Genasal Decongestant (Oxymetazoline)
  • Genaphed (Pseudoephedrine)
 
Decongestants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, relieving pain, and reducing fever.

Buyer Products:

  • Contac Allergy Sinus Day Caplets/Contac Non-Drowsy Formula Sinus Caplets (Pseudoephedrine Hydrochloride/Acetaminophen)

Target Products:

  • Genapap Max-Str Sinus (Pseudoephedrine and Acetaminophen)
Decongestants/Antitussives/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing coughs and relieving pain and fever.

Buyer Products:

  • Contac Day Cold & Flu Caplets/Contac Severe Cold & Flu Non-Drowsy Caplets (Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
  • Contac Jr. Children's Cold Medicine (Phenylpropanolamine Hydrochloride/Dextromethorphan Hydrobromide/Acetaminophen)
 
Decongestants/Antitussives/Expectorants/Analgesics/Antipyretics
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing the cough, helping in the ejection of mucous and helping relieve fever and pain.

Buyer Products:

  • Contac Cough & Chest Cold (Pseudoephedrine Hydrochloride/Dextromethorphan Hydrobromide/Guaifenesin/Acetaminophen)
 
Expectorants
Therapeutics that treat coughs and colds by helping in the ejection of mucous.

Target Products:

  • Guiatuss Clear DM (Guaifenesin)
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress the inflammation in the upper respiratory tract with steroidal compounds.

Buyer Products:

  • Beconase AQ (Beclomethasone Dipropionate, Monohydrate)

Target Products:

  • Triamcinolone Acetonide Nasal Spray
  • Nasacort AQ Nasal Spray (Triamcinolone Acetonide)
Nasal Dryness  
Moisturizing Agents
Therapeutics that treat nasal dryness by providing moisture to the nasal passages.

Buyer Products:

  • Breathe Right Vapor Shot
  • Breathe Right Snore Relief Throat Spray
  • Breathe Right Saline Spray
 
Surgery
Cardiovascular System  
Complications  
Ischemia  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Target Products:

  • Bivalirudin
 
Digestive System  
Post-Operative Ileus/Constipation  
Opioid Receptor Antagonists
Therapeutics that treat constipation by blocking the mu opioid receptors in the intestines.

Buyer Products:

  • Entereg (Alvimopan)
 
General
Complications
Nausea/Vomiting
Dopamine Receptor Blocking Agents
Therapeutics that treat or prevent post surgical nausea and vomiting through a combination of blocking neurotransmitters and gastrointestinal movement stimulants.

Target Products:

  • Metoclopramide HCl
 
Serotonin Receptor Antagonists
Therapeutics that prevent or treat post surgical nausea and vomiting by blocking the receptors that bind serotonin, a neurotransmitter.

Buyer Products:

  • Zofran/Zofran ODT (Ondansetron Hydrochloride)
 
Musculoskeletal System
Deep Vein Thrombosis (DVT)
Anticoagulating Agents (Anticoagulants)
Thrombin Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by blocking an enzyme involved in the clotting process.

Buyer Products:

  • Arixtra (Fondaparinux Sodium)

Target Products:

  • Enoxaparin Sodium
Factor Xa Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by preventing thrombin generation, which is responsible for blood clotting.

Buyer Products:

  • Fraxiparine (Nadroparin)
 
Neurology  
Seizures  
Sodium Channel Modulators
Therapeutics that treat seizures by controlling the entrance of sodium into the nerve cells.

Target Products:

  • Fosphenytoin Sodium
  • Prompt Phenytoin Sodium
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of surgical complications in early stages of clinical research where human subject is involved.

Buyer Products:

  • Vestipitant/GW597599
 
Toxicology
Chemical Poisoning  
Digoxin  
Digoxin Binding Agents
Therapeutics that treat toxicity due to ingestion of excessive digoxin by competitively binding to digoxin, making them unavailable for binding at their site of action on cells in the body.

Buyer Products:

  • Digibind (Digoxin Immune Fab)
 
Heavy Metal Poisoning  
Chelating Agents  
Iron
Therapeutics that form chemical complexes with iron and are subsequently excreted.

Target Products:

  • Deferoxamine Mesylate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of toxicity in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK1144814 (NK1/NK3 Antagonist)
  • GSK618334 (Dopamine D3 Antagonist)
  • GSK598809 (Dopamine D3 Antagonist)
  • GSK468816 (Glycine Receptor Antagonist)
 
Substance Abuse
Withdrawal
Alcohol  
Antihistamines
Therapeutics that treat alcohol withdrawal by blocking the H2 receptors and thus the effects of histamines.

Target Products:

  • Hydroxyzine Pamoate
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Target Products:

  • Diazepam
 
Narcotics  
Opioid Analgesics
Therapeutics that treat narcotic withdrawal by providing the body with a milder opioid substitute.

Target Products:

  • Buprenorphine HCl
 
Nicotine (Smoking Cessation)  
Nicotine Conjugate Vaccine
Therapeutics that treat nicotine withdrawal by stimulating the immune system to produce antibodies that bind to nicotine, and preventing it from crossing the blood-brain barrier.

Buyer Products:

  • NicVax (Nicotine Conjugate Vaccine)
 
Nicotinic Receptor Agonists
Therapeutics that treat nicotine withdrawal by activating nicotine receptors thus reducing cravings for nicotine.

Buyer Products:

  • Commit Lozenge (Fast-Acting Nicotine Lozenge)
  • NicoDerm CQ (Nicotine Transdermal System)
  • Nicorette (Nicotine Polacrilex Gum)
 
Serotonin/Norepinephrine Reuptake Inhibitors
Therapeutics that increase the concentration of several neurotransmitters in the brain by inhibiting their uptake.

Buyer Products:

  • Zyban (Bupropion Hydrochloride)
 
Transplantation  
Bone Marrow  
Complications  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics containing biological proteins that stimulate the formation of certain white blood cells called granulocytes.

Target Products:

  • Neutroval (Filgrastim)/Generic Neupogen/Formerly XM02
 
Urology
Male Genital Disorders
Penile
Erectile Dysfunction (Impotence)
Phosphodiesterase Type 5 Inhibitors (PDE-5 Inhibitors)
Therapeutics that inhibit the breakdown of phosphodiesters thereby increasing levels of Nitric Oxide which help in dilating the blood vessels in the penis.

Buyer Products:

  • Levitra (Vardenafil Hydrochloride)

Target Products:

  • Sildenafil Citrate
Vasodilatory Agents
Therapeutics that increase blood flow in the penis by dilating blood vessels.

Target Products:

  • Alprostadil
 
Prostate
Benign Prostate Hyperplasia (BPH)
5-Alpha Reductase Inhibitors
Therapeutics that inhibit the transformation of testosterone into dihydrotestosterone (DHT), a substance that causes enlargement of the prostate.

Buyer Products:

  • Avodart (Dutasteride)

Target Products:

  • Finasteride 5 MG
5-Alpha Reductase Inhibitors/Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that inhibit the transformation of testosterone into dihydrotestosterone (DHT)--a substance that causes enlargement of the prostate, and also causes the smooth muscle in the prostate to relax and decreasing the constriction on the urinary tract.

Buyer Products:

  • Duodart (Avodart + Alpha Blocker) (5-Alpha Reductase Inhibitor + Alpha Blocker)
  • Jalyn (Dutasteride 0.5mg/Tamsulosin0.4mg)
 
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that increase blood flow by acting on the alpha adrenergic receptors thus causing the smooth muscle in the prostate to relax and decreasing the constriction on the urinary tract.

Target Products:

  • Tamsulosin Hydrochloride
  • Doxazosin Mesylate
 
Testicular  
Abnormal Puberty  
Precocious  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat puberty disorders by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Leuprolide
 
Hypogonadism  
Androgens
Therapeutics that treat hypogonadism by providing male sex hormones.

Target Products:

  • Testosterone Cypionate Injection
  • Bio-T-Gel (Testosterone Gel)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK1278863 (Prolyl Hydroxylase Inhibitor)
  • Solabegron (Beta-3 Adrenergic Agonist)
  • Dutasteride/Testosterone
  • GSK557296 (Oxytocin Antagonist)
 
Urological Disorders
Bladder
Cystitis  
Urotoxin Neutralizing Agents
Therapeutics that inhibit cystis induced by toxic therapeutics by neutralizing these therapeutics.

Target Products:

  • Mesna
 
Neurogenic Bladder Disease  
Anticholinergic Agents
Therapeutics that block the actions of choline and other cholinergic agents.

Target Products:

  • Oxybutynin Chloride
 
Urinary Frequency/Urge Incontinence
Anticholinergic Agents
Therapeutics that treat the inability to control urinary excretory functions by blocking the actions of choline and other cholinergic agents.

Target Products:

  • Oxybutynin Vaginal Ring/DR 3001
  • Oxybutynin Chloride
 
Muscarinic Receptor Antagonists
Therapeutics that treat COPD by blocking the action of choline and other cholinergic agents from binding to the muscarinic receptor.

Buyer Products:

  • Vesicare (Solifenacin Succinate)
 
Kidney (Renal)  
Chronic Renal Failure (CRF)  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine.

Target Products:

  • Furosemide
  • Torsemide
  • Bumetanide
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Target Products:

  • Triamterene and Hydrochlorothiazide
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Hydrochlorothiazide
  • Metolazone
 
Hyperparathyroidism  
Calcimimetic Agents
Therapeutics that treat hyperparathyroidism by decreasing parathyroid hormone levels, which may provide effective reduction of calcium levels.

Target Products:

  • Cinacalcet
 
Vitamin D Analogs
Therapeutics that provide the body with vitamin D like substances that help regulate the levels of calcium and phosphate in the blood.

Target Products:

  • Paricalcitol
 
Hyperphosphatemia  
Phosphate Binding Agents
Therapeutics that treat abnormal levels of phosphate in the blood by binding to excess phosphate groups.

Target Products:

  • Lathanum Carbonate
 
Diabetic Nephropathy  
Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors)
Therapeutics that treat diabetes induced kidney diseases by inhibiting a certain enzyme necessary for regulation of blood pressure.

Target Products:

  • Captopril
 
Angiotensin II Receptor Antagonists
Therapeutics that treat diabetes induced kidney disease by blocking the angiotensin II receptor.

Target Products:

  • Losaratan Potassium
 
Weight Management
Anorexia (Appetite Loss)  
Progestins
Therapeutics that treat weight loss and other conditions arising from the uncontrolled loss of appetite by administration of hormone progestins.

Target Products:

  • Megestrol Acetate
 
Cachexia  
Progestins
Therapeutics that treat cachexia by providing female hormones.

Target Products:

  • Megestrol Acetate
 
Obesity
Lipase Inhibitors
Therapeutics that reduce the absorption of fat by inhibiting production of lipase, which is an enzyme that helps breaking down fat in the food.

Buyer Products:

  • Xenical (Orlistat)
  • Alli (Orlistat)
 
Sympathomimetic Agents
Therapeutics that suppress appetite by stimulating the adrenergic receptors and produce adrenergic chemicals.

Target Products:

  • Barr Labs Phentermine Hydrochloride
  • Laquinimod
  • Adipex-P (Phentermine Hydrochloride)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • GSK2245840 / SRT2104 (SIRT1 Activator)
  • GSK1521498 (Mu-Opioid Receptor Inverse Agonist)
  • 189075 (Remoglifozin Etabonate)
 
Wound Management  
Burns  
Maintenance  
Tissue (Skin) Removal  
Debriding Agents
Therapeutics that treat skin injuries caused by fire or excessive heat by removing dead skin from the wound by catalyzing the breakdown of collagen.

Target Products:

  • Debrase Gel Dressing
 
Medical Devices
Clinical Diagnostics  
Chemistry  
Reagents  
Test Kits  
Microbiology Identification  
Bacterial
Test kits used to identify bacterial organisms in a culture source. Biochemical presumptive identification test kits are included, as well as kits for testing bacterial sensitivity to antibiotics.

Buyer Products:

  • ID Biomedical - Velogene Genomic Identification Assay for Vancomycin-Resistant Enterococci (VRE)
  • ID Biomedical - Velogene Genomic Identification Assay for MRSA
 
Immunoassays  
Reagents  
Test Kits  
Allergy
Immunassay kits used to detect and quantitate allergy associated analytes.

Buyer Products:

  • T.R.U.E. Test
 
Drug Delivery  
Pulmonary Delivery  
Aerosol Therapy  
Metered Dose  
Dry Powder  
Inhalers (DPI)
Mouthpiece-type of medical devices from which the patients inhale the medication mixture

Buyer Products:

  • Diskus/Accuhaler
 
Liquid  
Breath Actuated (BAI)
Inhalation devices which are activated by the patients' inspiration

Buyer Products:

  • Surehaler
 
Manual
Inhalation devices which are activated by the patient's manual control

Buyer Products:

  • MDI Dose Counter
 
Radiology  
Nuclear  
Gamma Camera  
Contrast Agents  
Radionuclides  
Adjuncts
Radioactive materials that are introduced to the body for nuclear imaging purposes.

Target Products:

  • Adenosine Injection
 
Respiratory  
Treatment  
Nasal Expanders
Device designed to expand the nasal passages.

Buyer Products:

  • Breathe Right Vapor Strip
  • Breathe Right Nasal Strip
  • Breathe Right Mentholated Nasal Strip
  • Breathe Right Vapor Shot Portable Vaporizer
 
Nutritional Health  
Dietary/Naturopathic Supplements  
General Health
Products consisting of dietary/naturopathic supplements that are intended to support general health.

Buyer Products:

  • GlaxoSmithKline plc
 
Women`s Health
Products consisting of dietary/naturopathic supplements that are intended to support women's health.

Buyer Products:

  • GlaxoSmithKline plc
 
Outsourced Biomedical Services
Development/Manufacturing Services
Contract Manufacturing Organizations (CMO)
Biopharmaceutical OEM
Active/Intermediate Chemicals
Intermediate and active ingredient contract manufacturing organizations that produce large quantities of small molecule compounds for use in final dosage forms.

Target Products:

  • ratiopharm - Merckle Biotec GmbH
  • TEVA API Services
 
Biologics
Active Ingredient Contract Manufacturing Organizations (CMO) that manufacture antibodies, proteins, and genetic materials.

Buyer Products:

  • Manufacturing Services

Target Products:

  • ratiopharm - Merckle Biotec GmbH
Final Dosage Forms
Contract Manufacturing Organizations (CMO) that produce large quantities of drug products in final dosage forms ready to be sold to end users.

Target Products:

  • ratiopharm - Merckle Biotec GmbH
  • Taiyo Pharmaceutical Industry Co. Ltd.
 
Drug Delivery Technology  
Oral Delivery  
Molecular Complex
Drug Delivery Technologies used to deliver drugs using a substance with the drugs embedded in it.

Target Products:

  • Cephalon, Inc. - ORASOLV
  • Cephalon, Inc. - DURASOLV
 
Transmucosal  
Drug Matrix
Drug Delivery Technologies used to deliver drugs using a substance with the drugs embedded in it.

Target Products:

  • Cephalon, Inc. - ORAVESCENT
 
Scientific Products  
Bioanalytical Instruments  
Bioanalytical Consumables  
Cell Biology  
Cell Culture  
Cell Lines
Cell biology consumables that is a permanently established cell culture which proliferates indefinitely given appropriate fresh medium and space.

Buyer Products:

  • ACE System
 
Veterinary Products and Services  
Veterinary Pharmaceuticals
The Veterinary Pharmaceuticals Subsector includes companies that manufacture veterinary pharmaceuticals and vaccines for the prevention and treatment of veterinary diseases.

Target Products:

  • IVX Animal Health, Inc.
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Novartis SA n/a 142,003.622 16.43 9.70 2.40 2.46 101.58
Merck & Co Inc n/a 116,518.823 16.80 9.96 2.42 2.49 12.01
Amgen Inc n/a 63,900.920 17.21 11.66 4.01 3.99 19.32
Astrazeneca PLC n/a 55,862.085 6.70 6.82 1.71 1.94 90.39
Gilead Sciences Inc n/a 38,526.468 14.94 14.61 4.41 4.22 n/a
Biogen IDEC Inc n/a 31,914.176 25.95 21.64 6.21 6.01 9.58
Allergan Inc n/a 27,300.906 27.16 21.26 4.93 4.66 12.31
Dr Reddy'S Laboratories Ltd n/a 5,067.326 0.43 17.13 0.07 n/a 0.12
Salix Pharmaceuticals Ltd n/a 2,896.808 29.50 20.09 4.78 3.93 6.09
United Therapeutics Corp n/a 2,428.303 9.58 9.37 3.09 2.82 2.40
Ariad Pharmaceuticals Inc n/a 2,118.104 n/a -12.64 83.65 186.35 8.23
Taro Pharmaceutical Industries Ltd n/a 1,771.145 9.70 n/a 3.50 n/a 3.12
Akorn Inc n/a 1,225.611 26.11 26.29 7.51 4.66 29.45
Momenta Pharmaceuticals Inc n/a 707.734 6.08 -18.63 3.09 9.01 n/a
Spectrum Pharmaceuticals Inc n/a 589.433 6.90 7.47 2.82 2.58 2.96
Emergent BioSolutions Inc n/a 498.683 22.51 22.48 1.82 1.77 1.40
CytRx Corp n/a 447.174 n/a n/a 1,772.21 n/a 31.37
Arqule Inc n/a 310.543 n/a -19.38 7.32 7.88 11.26
Antares Pharma Inc n/a 299.459 n/a -98.00 15.16 11.98 9.97
Depomed Inc n/a 283.458 n/a -7.26 4.25 3.84 2.86
Xenoport Inc n/a 206.615 n/a -3.79 3.86 9.39 3.00
Buyer
  Pfizer Inc n/a 176,093.984 12.76 10.21 1.76 2.93 n/a
Procter & Gamble Co n/a 174,538.223 13.86 16.57 1.64 2.08 n/a
Target
  Novartis SA n/a 142,003.622 16.43 9.70 2.40 2.46 101.58
Merck & Co Inc n/a 116,518.823 16.80 9.96 2.42 2.49 12.01

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Shire PLC n/a 16,927.268 9.59 14.88 3.97 3.58 170.29
Human Genome Sciences Inc n/a 2,667.459 n/a -9.30 17.60 11.94 7.08
Codexis Inc n/a 112.024 n/a -5.42 0.90 0.89 1.45
Skyepharma PLC n/a 28.492 n/a n/a 0.34 n/a n/a
Gerresheimer AG n/a n/a n/a n/a n/a n/a n/a
Buyer
  Celldex Therapeutics Inc 98.00% 181.445 n/a -4.27 19.77 21.11 2.44
Anacor Pharmaceuticals Inc 53.00% 149.677 n/a -3.17 7.30 8.98 7.24
Target
  Antares Pharma Inc 44.00% 299.459 n/a -98.00 15.16 11.98 9.97
3M Co n/a 59,253.326 13.85 13.14 1.99 1.95 7.73
Astrazeneca PLC n/a 55,862.085 6.70 6.82 1.71 1.94 90.39
Shire PLC n/a 16,927.268 9.59 14.88 3.97 3.58 170.29
Valeant Pharmaceuticals International Inc n/a 14,153.627 107.56 10.97 5.14 4.15 n/a
Perrigo Co n/a 9,216.636 24.78 20.17 3.03 2.90 49.14
Human Genome Sciences Inc n/a 2,667.459 n/a -9.30 17.60 11.94 7.08
Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Impax Laboratories Inc n/a 1,378.523 21.35 11.71 2.59 2.16 2.50
OncoGenex Pharmaceuticals Inc n/a 123.805 n/a -5.69 22.06 7.95 1.58
Compugen Ltd n/a 123.460 n/a n/a n/a n/a 6.31
Codexis Inc n/a 112.024 n/a -5.42 0.90 0.89 1.45
CEL-SCI Corp (New) n/a 82.974 n/a n/a 223.62 n/a 14.17
Savient Pharmaceuticals Inc n/a 60.888 n/a -0.56 5.16 3.02 n/a
Rexahn Pharmaceuticals Inc n/a 38.095 n/a n/a 1,023.53 n/a 3.56
Biosante Pharmaceuticals Inc n/a 37.380 n/a -1.39 76.55 50.78 0.98
Skyepharma PLC n/a 28.492 n/a n/a 0.34 n/a n/a
Autoimmune Inc n/a 0.039 n/a n/a 0.06 n/a 0.00

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Buyer
  Roche Holding AG n/a 139,114.120 24.15 10.09 2.04 2.93 n/a
Eli Lilly & Co n/a 46,816.943 10.86 12.39 1.95 2.07 4.89
Celgene Corp n/a 31,244.689 21.68 15.88 6.26 5.82 5.14
Allergan Inc n/a 27,300.906 27.16 21.26 4.93 4.66 12.31
Warner Chilcott PLC n/a 5,056.104 16.51 5.90 1.90 2.08 n/a
Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Pozen Inc n/a 194.151 4.94 -7.93 2.32 19.72 1.98
Farabi Pharmaceutical Co n/a n/a n/a n/a n/a n/a n/a
Ahmed Mohammed Abdul Wahab Naghi & Sons Co. n/a n/a n/a n/a n/a n/a n/a
Selcuk Ecza Deposu Ticaret ve Sanayi AS n/a n/a n/a n/a n/a n/a n/a
Corporativo Fragua SAB de CV n/a n/a n/a n/a n/a n/a n/a
Adherex Technologies Inc n/a n/a n/a n/a n/a n/a n/a
GAVI Alliance n/a n/a n/a n/a n/a n/a n/a
Government - Brazil n/a n/a n/a n/a n/a n/a n/a
PROTEK OJSC n/a n/a n/a n/a n/a n/a n/a
Government - United States n/a n/a n/a n/a n/a n/a n/a
World Health Organization (WHO) n/a n/a n/a n/a n/a n/a n/a
Target
  Watson Pharmaceuticals Inc n/a 9,376.965 34.60 12.22 1.79 1.71 385.88
Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Medicines Co n/a 1,127.778 5.02 19.57 1.32 2.12 2.90
Paladin Labs Inc n/a 837.215 15.61 n/a 5.64 n/a 2.71
Transcept Pharmaceuticals Inc n/a 94.523 n/a -5.86 5.71 10.32 1.60
H. Lundbeck A/S n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Shire PLC n/a 16,927.268 9.59 14.88 3.97 3.58 170.29
Human Genome Sciences Inc n/a 2,667.459 n/a -9.30 17.60 11.94 7.08
Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Impax Laboratories Inc n/a 1,378.523 21.35 11.71 2.59 2.16 2.50
Medicines Co n/a 1,127.778 5.02 19.57 1.32 2.12 2.90
Skyepharma PLC n/a 28.492 n/a n/a 0.34 n/a n/a
Lonza Group AG n/a n/a n/a 6.50 n/a n/a n/a
Buyer
  Pfizer Inc n/a 176,093.984 12.76 10.21 1.76 2.93 n/a
Roche Holding AG n/a 139,114.120 24.15 10.09 2.04 2.93 n/a
Target
  Procter & Gamble Co n/a 174,538.223 13.86 16.57 1.64 2.08 n/a
Novo-Nordisk A/S (vormals Novo Industri A/S) n/a 66,851.111 10.69 22.48 1.64 4.95 1.86
3M Co n/a 59,253.326 13.85 13.14 1.99 1.95 7.73
Shire PLC n/a 16,927.268 9.59 14.88 3.97 3.58 170.29
Watson Pharmaceuticals Inc n/a 9,376.965 34.60 12.22 1.79 1.71 385.88
Perrigo Co n/a 9,216.636 24.78 20.17 3.03 2.90 49.14
Human Genome Sciences Inc n/a 2,667.459 n/a -9.30 17.60 11.94 7.08
Myriad Genetics Inc n/a 2,087.998 26.06 19.08 4.44 4.27 3.60
Par Pharmaceutical Cos Inc n/a 1,425.793 26.90 10.14 1.48 1.33 n/a
Impax Laboratories Inc n/a 1,378.523 21.35 11.71 2.59 2.16 2.50
Medicines Co n/a 1,127.778 5.02 19.57 1.32 2.12 2.90
Genomic Health Inc n/a 933.427 114.21 n/a 4.35 4.06 7.62
Paladin Labs Inc n/a 837.215 15.61 n/a 5.64 n/a 2.71
Protalix BioTherapeutics Inc n/a 530.623 n/a 86.86 764.82 17.46 n/a
Antares Pharma Inc n/a 299.459 n/a -98.00 15.16 11.98 9.97
Biotime Inc n/a 196.455 n/a n/a 29.05 n/a 32.12

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 31,752.9 19,334.0 51,086.9
Other Revenue n/a n/a n/a
Total Revenue 31,752.9 19,334.0 51,086.9
Cost of Revenue 8,381.6 9,398.0 17,779.6
SG&A Expense 9,885.5 4,564.0 14,449.5
Depreciation & Amortization 25.0 33.0 58.0
Research & Development 4,511.6 1,133.0 5,644.6
Interest Expense n/a n/a n/a
Other Operating Expense -640.8 n/a -640.8
Unusual Expense (Income) 642.3 1,036.0 1,678.3
Total Expenses 22,805.3 16,164.0 38,969.3
Operating Income 8,947.6 3,170.0 12,117.6
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng -742.3 -185.0 -927.3
Gain/Loss On Sale Of Assets 1.0 n/a 1.0
Other, Net n/a n/a n/a
Income Before Taxes 8,134.3 2,985.0 11,119.3
Income Taxes 2,134.5 69.0 2,203.5
Income After Taxes 5,999.8 2,916.0 8,915.8
Minority Interest (IS) -229.3 -1.0 -230.3
Equity in Affiliates n/a -58.0 -58.0
Net Income - Excl. Xord. Items 5,770.5 2,857.0 8,627.5
Net Income - Incl. Xord. Items 5,770.5 2,857.0 8,627.5
Income Avail. to Common 5,770.5 2,857.0 8,627.5
Share Items
Basic Avg. Shares Outstanding 4,963.0 880.0 5,843.0
Basic EPS - Excl. Xord. Items 1.15 3.23 1.48
Basic EPS - Incl. Xord. Items 1.51 3.23 1.48
Full Dilution Adjustment n/a n/a n/a
Fully Diluted Shares Outstanding 5,035.0 882.0 5,917.0
F.D. EPS - Excl. Xord. Items 1.49 3.22 1.46
F.D. EPS - Incl. Xord. Items 1.49 3.22 1.46
Dividends Per Common Share 1.13 0.98 2.11
Balance Sheet
Assets
Cash and Equivalents 5,636.0 1,062.0 6,698.0
ST Investments 203.0 38.0 241.0
Accounts Receivable 5,840.0 6,056.0 11,896.0
Inventory 4,008.0 5,332.0 9,340.0
Other Current Assets 591.0 2,517.0 3,108.0
Current Assets 16,278.0 14,967.0 31,245.0
Accum D&A n/a n/a n/a
PPE, Net 8,616.0 6,083.0 14,699.0
Goodwill & Intangibles 11,264.0 28,213.0 39,477.0
Long Term Investments 1,199.0 1,044.0 2,243.0
Other Assets n/a n/a n/a
Other LT Assets 3,445.0 163.0 3,608.0
Total Assets 40,802.0 50,470.0 91,272.0
Liabilities
Accounts Payable 7,058.0 n/a 7,058.0
Payable/Accrued n/a 3,199.0 3,199.0
ST Debt 2,723.0 3,834.0 6,557.0
Curr Port of LTD & Cap Lease Oblg n/a 531.0 531.0
Other (Current) Liabilities 4,752.0 6,063.0 10,815.0
Current Liab. 14,533.0 13,627.0 28,160.0
LT Debt 11,992.0 10,157.0 22,149.0
Total LT Debt 11,992.0 10,157.0 22,149.0
Minority Interest (BS) 800.0 149.0 949.0
Deferred Taxes 824.0 2,210.0 3,034.0
Other LT Liab. 3,877.0 1,276.0 5,153.0
Total Liabilities 32,026.0 27,419.0 59,445.0
Shareholders Equity
Common Stock 1,390.0 n/a 1,390.0
Additional Paid in Capital 1,782.0 n/a 1,782.0
Retained Earnings 5,604.0 n/a 5,604.0
Other Equity n/a 23,051.0 23,051.0
Total Equity 8,776.0 23,051.0 31,827.0
Total Liab. & Equity 40,802.0 50,470.0 91,272.0
Shares Outstanding 4,962.0 942.0 5,904.0
Cash Flow
Operating Cash Flow
CF Net Income 5,999.8 2,858.0 8,857.8
CF Depreciation 2,085.3 -1,227.0 858.3
CF Deferred Taxes n/a 396.0 396.0
Other Non-Cash Items 2,949.8 1,624.0 4,573.8
Change in Working Capital -3,933.0 339.0 -3,594.0
Total Cash From Operating Activities 7,101.9 3,990.0 11,091.9
Investing Cash Flow (not calculated)
Capital Expenditures -1,510.9 1,196.0 -314.9
Other Investing Cash Flows 531.0 -8,315.0 -7,784.0
Total Cash From Investing Activities -979.9 -7,119.0 -8,098.9
Financing Cash Flow (not calculated)
Dividends Paid -4,157.3 1,016.0 -3,141.3
Purchase Or Sale of Stock -1,996.7 1,158.0 -838.7
Purchase and Retirement of Debt 1.9 -32.0 -30.1
Other Financing Cash Flow -1,138.9 1,351.0 212.1
Total Cash From Financing Activities -7,291.0 3,493.0 -3,798.0
Exchange Rate Effects -91.8 -23.0 -114.8
Net Change in Cash -1,260.9 341.0 -919.9
Cash Taxes Paid -1,095.5 n/a -1,095.5
Cash Interest Paid -271.6 n/a -271.6