Summary

Other Scenarios:

Buyer: Merck Serono S.A. (ADR) (SRA) Last Price: 22.72 Market Cap.: 13.92B
Target: Barr Pharmaceuticals, Inc. (BRL) Last Price: 54.70 Market Cap.: 6.00B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
*Healthcare 879
Biopharmaceuticals 337
Medical Devices 247

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business

Buyer (Total: 38)
  • Zorbtive (Somatropin)
  • r-IFNB-1a (Recombinant Human Interferon Beta-1a)
  • r-IL-18bp (Recombinant Interleukin 18 Binding Protein)
  • PTP 1b Inhibitor
Target (Total: 155)
  • Hydroxyzine Pamoate
  • Pliva Cyproheptadine HCl
  • Pliva Ketorolac Tromethamine
  • Diphenhydramine Hydrochloride
Buyer
  • easypod
  • SeroJet
  • one.click
  • Rebiject/Rebiject II
Target
  • ViaSpan (Belzer UW)
  • ParaGard T 380A

Business Relationship Summary:

Top Key Suppliers

Top Key Customers

Buyer (Total: 13)
  • Bioject Medical Technologies Inc. (BJCT)
  • Rigel Pharmaceuticals, Inc. (RIGL)
  • Vernalis plc (ADR) (VNLSY)
  • Regeneron Pharmaceuticals, Inc. (REGN)
Target (Total: 3)
  • Mack-Cali Realty Corp. (CLI)
  • Indevus Pharmaceuticals (IDEV)
  • Common Sense Ltd.
Buyer (Total: 6)
  • Roche Holding Ltd. (ADR) (RHHBY)
  • Abbott Laboratories (ABT)
  • Amgen, Inc. (AMGN)
  • Akzo Nobel N.V. (ADR) (AKZOY)
Target (Total: 7)
  • McKesson Corporation (MCK)
  • Cardinal Health, Inc. (CAH)
  • AmerisourceBergen Corp. (ABC)
  • Walgreen Company (WAG)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 4,775 8,500
Revenue Per Employee 620,306.2 282,835.1
Total Revenue 739.2 599.4
Total Expenses 605.3 547.7
Other Revenue 83.6 35.6
Cost of Revenue 84.9 302.5
SG&A Expense 283.0 182.4
Research & Development 165.9 61.2
Other Operating Expense 71.4 0.0
Operating Income 134.0 51.7
Unusual Income 0.0 1.5
LT Debt to Capital 0.75 55.64
Fwd P/E n/a 17.93
Fwd P/Rev n/a 2.41
Book Value 3,682.9 1,498.8
Curr Portion of LTD/Cap Lease 0.0 650.9

Individual Company Summary

Focused

Buyer

Focused (): *Healthcare > Biopharmaceuticals > Neurology

Target

Focused (): *Healthcare > Biopharmaceuticals

Business Description

Buyer

Merck Serono S.A., formerly Serono S.A. is a biotechnology company that discovers, develops, manufactures and markets therapeutic products for the treatment of human diseases in selected therapeutic areas. It focuses on specialized markets of neurology, reproductive health, growth and metabolism, dermatology, oncology and autoimmune diseases and has eight biotechnology products on the market. The Company has a global presence with operations in more than 40 countries, main production facilities in four countries and sales in over 90 countries. As of December 31, 2006, the Company had approximately 25 ongoing development projects, based on proteins, monoclonal antibodies and small molecules. In January 2007, Merck KGaA acquired majority interest in Serono S.A.

Target

Barr Pharmaceuticals, Inc. is primarily a holding company. The Company's subsidiaries, Barr Laboratories, Inc. and Duramed Pharmaceuticals, Inc., develop, manufacture and market generic and proprietary pharmaceutical products, respectively. It operates in two business segments. In the generic pharmaceutical segment, it manufactures and distributes approximately 150 different dosage forms and strengths of approximately 75 different generic pharmaceutical products, including 22 oral contraceptive products that represent the largest category of its generic product portfolio. In the proprietary pharmaceutical segment, the Company manufactures and distributes 19 proprietary pharmaceutical products, largely concentrated in the women's healthcare therapeutic category. These products include SEASONALE and SEASONIQUE extended-cycle oral contraceptive products, and Cenestin (synthetic conjugated estrogens, A) and ENJUVIA (synthetic conjugated estrogens, B) line of hormone therapy products.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 89.38 57.2
Operating Margin % 26.26 -3.19
Quick Ratio 1.69 1.27
Current Ratio 2.38 1.83
Coverage Ratio 0.04 0.69
Total Assets 5,601.4 4,799.4
Return on Equity % 19.97 -16.22
Return on Assets % 13.13 -5.07
Cash+ ST Inv. Per Share 3.46 7.79
Total Debt 804.7 2,530.8
Total Debt to Equity % 21.85 168.85
Total Debt to Tangible Equity % 23.91 n/a
Debt to Asset % 14.37 52.73

Product Summary

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
 
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
 
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
 
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
 
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes therapeutics that treat female genital disorders, pregnancy, and childbirth.
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
 
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
 
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
 
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
 
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
 
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
 
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes herapeutics that treat and manage weight disorders.
Medical Devices
Drug Delivery
The Drug Delivery Subsector includes medical devices that facilitate the delivery of medications through different anatomical entryways, including blood vessels, skin, the mouth, and the lungs. Common devices in this sector include vascular access catheters, needles, implants, and inhalers.
 
General Surgery
The General Surgery Subsector includes medical devices that perform general, non-specialty surgeries; these devices are often general in scope and are used in procedures involving various parts of the body.
 
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes medical devices that diagnose and treat female reproductive diseases; devices used to care for women during pregnancy, childbirth, and the post-partum period are also included in this sector.
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies  
Dermatology  
Antihistamines
Products that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Hydroxyzine Pamoate
 
Antihistamines/Antiserotonins
Therapeutics that inhibit the inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Pliva Cyproheptadine HCl
 
Ophthalmology  
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Pliva Cyproheptadine HCl
 
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation preventingcyclooxygenase activity.

Target Products:

  • Pliva Ketorolac Tromethamine
 
Systemic  
Anaphylactic Shock  
Adjunctive Treatments  
Antihistamines/Antiserotonins
Therapeutics that assist the primary treatment of a life-threatening systemic allergic reaction resulting from secondary or subsequent exposure to a foreign substance by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Pliva Cyproheptadine HCl
 
Upper Respiratory  
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Target Products:

  • Diphenhydramine Hydrochloride
  • Fexofenadine Hydrochloride (12 Hours Extended Release)
  • Fexofenadine Hydrochloride
 
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Pliva Cyproheptadine HCl
 
Antihistamines/Decongestants
Therapeutics that block the inflammatory action of histamines and relieve or prevent coughs.

Target Products:

  • Fexofenadine/Pseudoephedrine
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress inflammation using a steroidal compound.

Target Products:

  • Triamcinolone Acetonide Nasal Spray
 
Cardiovascular System  
Heart Disorders  
Angina  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat chest pains by inhibiting stimulation of beta adrenergic receptors of the heart muscle.

Target Products:

  • Pliva Propranolol Hydrochloride
 
Arrhythmia  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat abnormal rhythm of the heart beat by inhibiting the stimulation of beta adrenergic receptors of the heart muscle.

Target Products:

  • Pliva Propranolol Hydrochloride
 
Sodium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium into heart muscle cells.

Target Products:

  • Flecainide Acetate
  • Pliva Propafenone HCl
 
Sodium Channel Blocking Agents/Potassium Channel Blocking Agents
Therapeutics that treat abnormal rhythm of the heart by preventing the entry of sodium and potassium into heart muscle cells.

Target Products:

  • Amiodarone Hydrochloride
 
Heart Failure (HF)  
Complications  
Edema  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of water and sodium, but not potassium in urine.

Target Products:

  • Amiloride Hydrochloride/Hydrochlorothiazide
  • Triamterene/Hydrochlorothiazide
 
Thiazide Diuretic Agents
Therapeutics that treat the accumulation of fluid by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Pliva Chlorthalidone
 
Myocardial Infarction (MI)  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Target Products:

  • Pliva Propranolol Hydrochloride
 
Free Fatty Acid Inhibitors
Therapeutics that treat irreversible damage to the heart muscle by inhibiting the release of fatty acids from adipose tissue.

Target Products:

  • Niacin Extended-Release
  • Niaspan (Niacin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat irreversible damage to the heart muscle by preventing the synthesis of cholesterol.

Target Products:

  • Pravastatin Sodium
 
Vascular Disorders  
Aneurysms  
Hemorrhage  
Calcium Channel Blocking Agents
Therapeutics that treat bleeding from aneurysms by blocking the flow of calcium ions from the blood vessel wall.

Target Products:

  • Nimodipine
 
Atherosclerosis  
Free Fatty Acid Inhibitors
Therapeutics that treat the narrowing or hardening of arteries by inhibiting the release of fatty acids from adipose tissue.

Target Products:

  • Niaspan (Niacin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the narrowing or hardening of the arteries by preventing the synthesis of cholesterol.

Target Products:

  • Pravastatin Sodium
 
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that prevent or treat clots in blood vessels by preventing blood clots from forming.

Target Products:

  • Warfarin Sodium
 
Hypertension  
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that treat high blood pressure by blocking alpha adrenergic receptors of the heart muscle.

Target Products:

  • Pliva Doxazosin Mesylate
 
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle.

Target Products:

  • Duramed Zebeta (Bisoprolol Fumarate)
  • Pliva Propranolol Hydrochloride
 
Beta Receptor Blocking Agents (Beta Blockers)/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Target Products:

  • Pliva Propranolol Hydrochloride/Hydrochlorothiazide
  • Duramed Ziac (Bisoprolol Fumarate/Hydrochlorothiazide)
 
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of water and sodium, but not potassium in urine.

Target Products:

  • Triamterene/Hydrochlorothiazide
  • Amiloride Hydrochloride/Hydrochlorothiazide
 
Thiazide Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium ions, and water in urine.

Target Products:

  • Pliva Chlorthalidone
 
Vasodilatory Agents
Therapeutics that treat high blood pressure by causing relaxation of the blood vessels.

Target Products:

  • Pliva Hydralazine
 
Peripheral Vascular Disease  
Blood Viscosity Reducing Agents
Therapeutics that treat arterial obstruction outside of the heart by altering the flow of red blood cells.

Target Products:

  • Pliva Pentoxifylline
 
Free Fatty Acid Inhibitors/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat arterial obstruction outside of the heart by inhibiting the release of fatty acids from adipose tissue and blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Advicor (Niacin/Lovastatin)
 
Thromboembolism  
Anticoagulating Agents (Anticoagulants)  
Platelet Aggregation Inhibitors  
Phosphodiesterase Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing platelets from clumping together.

Target Products:

  • Dipyridamole
 
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Target Products:

  • Warfarin Sodium
 
Tremors  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that prevent or treat involuntary trembling by blocking the beta adrenergic receptors in muscle tissue.

Target Products:

  • Pliva Propranolol Hydrochloride
 
Dermatology  
Acne  
Vulgaris  
Antibacterial Agents  
Macrolides
Therapeutics that treat acne vulgaris caused by bacterial infection by inhibiting RNA-dependent bacterial protein synthesis.

Target Products:

  • Erythromycin
 
Tetracyclines
Therapeutics that treat acne caused by bacterial infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Target Products:

  • Tetracycline Hydrochloride
 
Retinoids/Vitamin A Analogs
Therapeutics that treat acne by helping in cell differentiation as well as prevent cell proliferation.

Target Products:

  • Claravis (Isotretinoin)
 
Lesion/Scaling Disorders  
Chronic Urticaria  
Antihistamines
Therapeutics that treat allergic skin conditions by blocking the action of histamines.

Target Products:

  • Fexofenadine Hydrochloride
  • Fexofenadine Hydrochloride (12 Hours Extended Release)
 
Pruritus  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Hydroxyzine Pamoate
 
Psoriasis  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat a slow growing, chronic inflammatory skin disorder characterized by dry, scaling patches by inhibiting an enzyme needed for the synthesis of DNA.

Target Products:

  • Trexall (Methotrexate)
  • Methotrexate Sodium
 
Immunosuppressants
Therapeutics that treat a slow growing, chronic inflammatory skin disorder characterized by dry, scaling patches by suppressing the immune system.

Target Products:

  • Pliva Cyclosporine
 
Digestive System
Gastrointestinal Tract Disorders
Gastroduodenal Disorders  
Peptic Ulcers  
Duodenal  
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Target Products:

  • Pliva Cimetidine
 
Gastric  
H2 Receptor Antagonists
Therapeutics that treat peptic ulcers by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Target Products:

  • Pliva Cimetidine
 
Gastroesophageal Disorders  
Acid Indigestion/Heartburn  
H2 Receptor Antagonists
Therapeutics that treat indigestion by blocking the action of histamine at the H2 receptors.

Target Products:

  • Pliva Cimetidine
 
Gastroesophageal Reflux Disease (GERD)  
Dopamine Receptor Blocking Agents
Therapeutics that treat Gastroesophageal Reflux Disease (GERD) by blocking dopamine receptor and stimulating gastrointestinal movement without stimulating secretions from the pancreas, stomach or gall bladder.

Target Products:

  • Pliva Metoclopramide Hydrochloride
 
H2 Receptor Antagonists
Therapeutics that treat Gastroesophageal Reflux Disease by inhibiting the actions of receptors responsible for triggering acid release into the stomach.

Target Products:

  • Pliva Cimetidine
 
Gastroparesis  
Dopamine Receptor Blocking Agents
Therapeutics that treat gastroparesis by blocking the action of dopamine.

Target Products:

  • Pliva Metoclopramide Hydrochloride
 
Nausea/Vomiting  
Antihistamines
Therapeutics that inhibit inflammation by blocking the action of histamines on tissues.

Target Products:

  • Pliva Hydroxyzine Hydrochloride
 
Dopamine Receptor Blocking Agents
Therapeutics that treat or prevent nausea and vomiting by blocking the action of dopamine.

Target Products:

  • Pliva Metoclopramide Hydrochloride
  • Prochlorperazine Maleate
 
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Target Products:

  • Ondansetron Hydrochloride
  • Granisetron Hydrochloride
 
Intestinal Disorders
Intestinal Intubation  
Dopamine Receptor Blocking Agents
Therapeutics that cause bowel evacuation prior to intubation by blocking the action of dopamine.

Target Products:

  • Pliva Metoclopramide Hydrochloride
 
Short Bowel Syndrome  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development to treat a disorder resulting from operative resection of the intestines leading to impaired absorption and digestion in the intestines.

Buyer Products:

  • Zorbtive (Somatropin)
 
Liver Disorders
Cirrhosis  
Complications  
Edema  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Target Products:

  • Triamterene/Hydrochlorothiazide
 
Hepatitis  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • r-IFNB-1a (Recombinant Human Interferon Beta-1a)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • r-IL-18bp (Recombinant Interleukin 18 Binding Protein)
 
Endocrinology/Metabolism
Adrenal Gland Disorders  
Adrenocortical Insufficiency  
Synthetic Adrenocortical Steroids
Therapeutics that treat Adrenocortical Insufficiency by acting on the distal tubules of the kidney to enhance the reabsorption of sodium ions and to increase the urinary excretion of both potassium and hydrogen ions.

Target Products:

  • Fludrocortisone Acetate
 
Diabetes  
Induced Complications  
Central Diabetes Insipidus  
Antidiuretic Agents
Therapeutics that treat prevent the lose of water in the urine.

Target Products:

  • Desmopressin Acetate
 
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes  
Biguanides
Therapeutics that treat abnormally high blood glucose levels by decreasing the production of glucose in the liver, decreasing intestinal absorption of glucose and increasing peripheral uptake and utilization of glucose.

Target Products:

  • Metformin Hydrochloride Extended-Release
  • Metformin Hydrochloride
 
Biguanides/Insulin Stimulating Agents
Therapeutics that control high blood sugar by stimulating the release of insulin as well as decreasing the production of glucose in the liver.

Target Products:

  • Metformin Hydrochloride/Glipizide
 
Insulin Stimulating Agents (Sulfonylureas)
Therapeutics that treat non-insulin dependent diabetes by stimulating the secretion of insulin.

Target Products:

  • Acetohexamide
  • Pliva Chlorpropamide
 
General Hormone Treatments  
Estrogens
Therapeutics that treat hormonal disorders by providing estrogen.

Target Products:

  • Estradiol
  • Duramed Cenestin (Synthetic Conjugated Estrogens, A)
  • Estropipate
  • Duramed Enjuvia (Synthetic Conjugated Estrogens)
 
Prednisolones
Therapeutics that treat inflammation by preventing the accumulation of inflammatory cells, like macrophages and leukocytes to the inflammation sites.

Target Products:

  • Methylprednisolone
 
Intermediary Metabolism Disorders  
Gout  
Gouty Arthritis  
Urate Resorption Inhibitors
Therapeutics that treat gouty arthritis by preventing the active reabsorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate.

Target Products:

  • Sulfinpyrazone
 
Hyperuricemia  
Urate Resorption Inhibitors
Therapeutics that inhibit the resorption of urate from the kidneys.

Target Products:

  • Sulfinpyrazone
 
Hypercholesterolemia  
Free Fatty Acid Inhibitors
Therapeutics that treat the abnormally high concentrations of cholesterol by inhibiting the release of fatty acids from adipose tissue.

Target Products:

  • Niacin Extended-Release
  • Niaspan (Niacin)
 
Free Fatty Acid Inhibitors/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat elevated cholesterol by inhibiting the release of fatty acids from adipose tissue and blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Advicor (Niacin/Lovastatin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Pravastatin Sodium
 
Hyperlipidemia  
Free Fatty Acid Inhibitors
Therapeutics that inhibit the release of fatty acids from adipose tissue.

Target Products:

  • Niacin Extended-Release
  • Niaspan (Niacin)
 
Free Fatty Acid Inhibitors/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat hyperlipidemia by inhibiting the release of free fatty acid from adipose tissues as well as blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Advicor (Niacin/Lovastatin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Pravastatin Sodium
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PTP 1b Inhibitor
 
Pituitary Gland Disorders  
Lipodystrophy  
Growth Hormones
Therapeutics that treat lipodystrophy by providing a hormone which stimulates body growth and development.

Buyer Products:

  • Serostim (Somatropin)
 
Severe Short Stature  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Geref (Sermorelin Acetate For Injection)
  • Saizen (Somatropin (rDNA Origin))
 
Turner`s Syndrome  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Saizen (Somatropin (rDNA Origin))
 
Reproductive Disorders
Amenorrhea
Progestins
Female sex hormone necessary for the development of the female reproductive system.

Buyer Products:

  • Crinone (Progesterone Gel)

Target Products:

  • Medroxyprogesterone
  • Duramed Aygestin (Norethindrone Acetate)
Menopause  
Estrogens
Therapeutics that are female sex hormones.

Target Products:

  • Duramed Cenestin (Synthetic Conjugated Estrogens, A)
  • Estradiol
  • Estropipate
  • Duramed Enjuvia (Synthetic Conjugated Estrogens)
 
Estrogens/Progestins
Therapeutics that are mixture of two female sex hormones that are important for the development of the female reproductive system.

Target Products:

  • Duramed Prefest (17-Estradiol/Norgestimate)
  • Nevis (Norethindrone Acetate/Ethinyl Estradiol)
 
Progestins
Therapeutics that are female sex hormones.

Target Products:

  • Medroxyprogesterone
 
Hematology  
Hemophilia  
Hemophilia A  
Antidiuretic Agents
Therapeutics that treat prevent the loss of water in the urine.

Target Products:

  • Desmopressin Acetate
 
Red Blood Cell (RBC) Disorders  
Anemia  
Folic Acid Derivatives
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues caused by folic acid deficiency.

Target Products:

  • Leucovorin
 
Serum Factor Disorders  
Hypercholesterolemia  
Free Fatty Acid Inhibitors
Therapeutics that treat the abnormally high concentrations of cholesterol by inhibiting the release of fatty acids from adipose tissue.

Target Products:

  • Niacin Extended-Release
  • Niaspan (Niacin)
 
Free Fatty Acid Inhibitors/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat the abnormally high concentrations of cholesterol by inhibiting the release of fatty acids from adipose tissue and blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Advicor (Niacin/Lovastatin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Pravastatin Sodium
 
Hyperlipidemia  
Free Fatty Acid Inhibitors
Therapeutics that inhibit the release of fatty acids from adipose tissue.

Target Products:

  • Niacin Extended-Release
 
Free Fatty Acid Inhibitors/HMG CoA Reductase Inhibitors (Statins)
Therapeutics that treat hyperlipidemia by inhibiting the release of free fatty acid from adipose tissues as well as blocking cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Advicor (Niacin/Lovastatin)
 
HMG CoA Reductase Inhibitors (Statins)
Therapeutics that block cholesterol synthesis by binding a key enzyme in the synthesis process.

Target Products:

  • Pravastatin Sodium
 
Hyperuricemia  
Urate Resorption Inhibitors
Therapeutics that prevents the resorption of urate within the kidneys.

Target Products:

  • Sulfinpyrazone
 
Hypokalemia  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat hypokalemia by promoting excretion while inhibiting the removal of potassium.

Target Products:

  • Triamterene/Hydrochlorothiazide
 
Thrombocyte (Platelet) Disorders  
Thrombocythemia  
Megakaryocyte Maturation Inhibitors
Therapeutics that prevents the maturation of platelet producing cells.

Target Products:

  • Anagrelide Hydrochloride
 
Immunology
Autoimmune Disorders
Arthritis  
Rheumatoid Arthritis (RA)  
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Target Products:

  • Pliva Salsalate
  • Pliva Diclofenac Sodium
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Dihydrofolate Reductase Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the action of the dihydrofolate enzyme.

Target Products:

  • Methotrexate Sodium
  • Trexall (Methotrexate)
 
Pyrimidine Synthesis Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the overproduction of immune cells.

Target Products:

  • Leflunomide
 
Immunotherapy  
Immunosuppressants
Therapeutics that treat chronic inflammation of the joints by inhibiting a full immune response.

Target Products:

  • Pliva Cyclosporine
 
Multiple Sclerosis (MS)  
Adenosine Deaminase Inhibitors
Therapeutics that treat multiple sclerosis by inhibiting the transformation of deoxyadenosine into deoxyinosine, thereby impairing the proliferation of certain white blood cells.

Buyer Products:

  • Mylinax (Cladribine)
 
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that downregulates the antibody response of the immune system.

Buyer Products:

  • Rebif (Recombinant Interferon Beta-1a)
 
Topoisomerase II Inhibitors
Therapeutics that treat a neurodegenerative disease characterized by the gradual accumulation of plaques on the nerve sheaths an enzyme that inhibits the proliferation of cells.

Buyer Products:

  • Novantrone (Mitoxantrone Hydrochloride)
 
Psoriasis  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat a chronic autoimmune disease characterized by thickened skin with silver scales by blocking the action of the dihydrofolate enzyme.

Target Products:

  • Methotrexate Sodium
  • Trexall (Methotrexate)
 
Immunosuppressants
Therapeutics that treat a chronic autoimmune disease characterized by thickened skin with silver scales by inhibiting a full immune response.

Target Products:

  • Pliva Cyclosporine
 
Immune Deficiency Disorders  
Hereditary Angioedema  
Gonadotropin Inhibitors
Therapeutics that treat swelling under the skin caused by the absence of an essential immune regulator by increasing levels of C4 complement component.

Target Products:

  • Danazol
 
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Target Products:

  • Didanosine Delayed Release
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • MMP-12 Inhibitor
  • r-IL-18bp (Recombinant Interleukin 18 Binding Protein)
  • JNK Inhibitor
  • Mylinax (Cladribine)
  • Atacicept/TACI-Ig
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • HuMax-TAC
  • Interferon Beta:Fc
  • NI-0401/NI-0501
 
Infectious Diseases
Bacterial  
Antibacterial Agents  
Broad Spectrum  
Antibiotics  
Macrolides
Therapeutics that treat a wide variety of infections by inhibiting RNA-dependent bacterial protein synthesis.

Target Products:

  • Pliva Azithromycin I.V.
  • Erythromycin
 
Nitroimidazoles
Therapeutics that treat a wide variety of infections by inhibiting bacterial protein synthesis and causing cell death.

Target Products:

  • Pliva Metronidazole
 
Quinolones/Fluoroquinolones
Therapeutics that treat a wide variety of infections by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Tetracyclines
Therapeutics that treat a wide variety of infections by inhibiting protein synthesis and also causing alterations in cytoplasmic membranes.

Target Products:

  • Tetracycline Hydrochloride
  • Demeclocycline Hydrochloride
 
Narrow Spectrum  
Otolaryngology (Ear/Nose/Throat)  
Otitis Media  
Macrolides/Sulfonamides
Therapeutics that treat infection and inflammation of the middle ear space and ear drum by inhibiting RNA-dependent bacterial protein synthesis and by inhibiting folic acid synthesis.

Target Products:

  • Erythromycin Ethylsuccinate/Sulfisoxazole
 
Respiratory System  
Pneumonia  
Quinolones/Fluoroquinolones
Therapeutics that treat inflammation of the lungs caused by bacterial infection by bacterial infection by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Respiratory Tract Infections  
Quinolones/Fluoroquinolones
Therapeutics that treat bacterial infections of the air passage involved in breathing, including the trachea, lungs and bronchi by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Tuberculosis  
Antitubercular Agents
Therapeutics that treat a bacterial infection of the lung by inhibiting bacterial and mycobacterial RNA synthesis.

Target Products:

  • Ethambutol Hydrochloride
  • Isoniazid
 
Systemic  
Leprosy  
Erythema Nodosum Leprosum (ENL)  
Immunomodulatory Agents
Therapeutics that treat a bacterial infection characterized by the formation of tender, red nodules on the front of the legs by stimulating the immune system.

Target Products:

  • Thalidomide
 
Urology  
Prostatitis  
Quinolones/Fluoroquinolones
Therapeutics that treat a wide variety of infections by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Urinary Tract Infections (UTI)  
Antibacterial Agents (Antibiotics)  
Quinolones/Fluoroquinolones
Therapeutics that treat bacterial infections of the urethra, urinary bladder, ureters, and kidneys by promoting breakage of bacterial DNA strands.

Target Products:

  • Ciprofloxacin
 
Mycological (Fungal)  
Antifungal Agents  
Broad Spectrum  
Azoles  
Imidazoles
Therapeutics that treat fungal infections by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Pliva Ketoconazole
 
Triazoles
Therapeutics that treat fungal infections by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Fluconazole
 
Narrow Spectrum  
Dermatology  
Candidiasis  
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the skin caused by yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Pliva Nystatin
 
Digestive System  
Mucous  
Candidiasis  
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the secretory lining of the tissues caused by a yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Pliva Nystatin
 
Nervous System  
Cryptococcal Meningitis  
Triazoles
Therapeutics that treat fungal infections of lining of the brain and the spinal cord by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Pliva Fluconazole
 
Otolaryngology (Ear/Nose/Throat)  
Esophageal Candidiasis  
Triazoles
Therapeutics that treat fungal infections of the esophagus caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Pliva Fluconazole
 
Oropharyngeal Candidiasis  
Azoles  
Triazoles
Therapeutics that treat fungal infections of the mouth and pahrynx caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Pliva Fluconazole
 
Polyene Macrolide Antibiotics
Therapeutics that treat fungal infections of the mucosa caused by yeast by binding to sterols on the fungal cell membrane which results in the loss of potassium and other small molecules from the cell.

Target Products:

  • Pliva Nystatin
 
Urology  
Vaginal Candidiasis  
Azoles  
Triazoles
Therapeutics that treat fungal infections of the female reproductive organ caused by yeast by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Target Products:

  • Pliva Fluconazole
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Target Products:

  • Adenovirus Vaccine
 
Protozoal  
Antiprotozoal Agents  
Broad Spectrum  
Nitroimidazoles
Therapeutics that treat infections caused by a wide variety of unicellular organisms by inhibiting protein synthesis and causing cell death.

Target Products:

  • Pliva Metronidazole
 
Narrow Spectrum  
Malaria  
Aminoquinolines
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by inhibiting parasite growth.

Target Products:

  • Mefloquine Hydrochloride
 
Viral
RNA Viruses
Flavivirus  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • r-IFNB-1a (Recombinant Human Interferon Beta-1a)
 
Retrovirus  
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Target Products:

  • Didanosine Delayed Release
 
Musculoskeletal System
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • r-IL-18bp (Recombinant Interleukin 18 Binding Protein)
  • Atacicept/TACI-Ig
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • FGF-18
 
Skeletal Disorders  
Bone Disorders  
Osteoporosis  
Hormonal Treatments  
Estrogens
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Target Products:

  • Estradiol
  • Estropipate
 
Estrogens/Progestins
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Target Products:

  • Duramed Prefest (17-Estradiol/Norgestimate)
  • Nevis (Norethindrone Acetate/Ethinyl Estradiol)
 
Joint Disorders  
Ankylosing Spondylitis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Pliva Diclofenac Sodium
 
Gouty Arthritis  
Urate Resorption Inhibitors
Therapeutics that treat gouty arthritis by preventing the active reabsorption of urate at the renal tubule thus increasing the excretion of urinary acid and lowering serum concentrations of urate.

Target Products:

  • Sulfinpyrazone
 
Osteoarthritis (OA)  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Pliva Salsalate
  • Pliva Diclofenac Sodium
 
Rheumatoid Arthritis (RA)  
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Target Products:

  • Pliva Salsalate
  • Pliva Diclofenac Sodium
 
Disease Modifying Anti-Rheumatic Drugs (DMARD)  
Dihydrofolate Reductase Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the action of the dihydrofolate enzyme.

Target Products:

  • Trexall (Methotrexate)
  • Methotrexate Sodium
 
Pyrimidine Synthesis Inhibitors
Therapeutics that alter or delay the rate of chronic joint inflammation by blocking the overproduction of immune cells.

Target Products:

  • Leflunomide
 
Immunotherapy  
Immunosuppressants
Therapeutics that treat rheumatoid arthritis by suppressing the immune system.

Target Products:

  • Pliva Cyclosporine
 
Neurology
Neurological Disorders  
Alzheimer`s Disease  
Acetylcholinesterase Inhibitors/Nicotinic Receptor Modulators
Therapeutics that treat Alzheimer's Disease by preventing the breakdown of a the neurotransmitter, acetylcholine, and by modulating the receptor that binds nicotine.

Target Products:

  • Galantamine Hydrobromide
 
Epilepsy  
Partial Seizures  
Complex  
Adjunctive Therapy  
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid as well as blocking the sodium channels which in turn block the conductance of electrical impulses through the brain.

Target Products:

  • Zonisamide
  • Topiramate
 
Monotherapy  
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat complex partial seizures by preventing the uptake of gamma-aminobutyric acid as well as blocking the sodium channels which in turn block the conductance of electrical impulses through the brain.

Target Products:

  • Topiramate
 
Simple  
Adjunctive Therapy  
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate
  • Zonisamide
 
Monotherapy  
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate
 
Primary Generalized Seizures  
Absence (Petit Mal)  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Clonazepam ODT
  • Pliva Valproic Acid
 
Monotherapy  
Calcium Channel Blocking Agents
Therapeutics that treat Petit Mal Seizures by preventing the entrance of calcium into nerve cells.

Target Products:

  • Pliva Ethosuximide
 
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Pliva Valproic Acid
  • Clonazepam ODT
 
Akinetic Pattern  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Clonazepam ODT
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Target Products:

  • Clonazepam ODT
 
Myoclonic  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevent nerve activation.

Target Products:

  • Clonazepam ODT
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevents nerve activation.

Target Products:

  • Clonazepam ODT
 
Tonic-Clonic (Grand Mal)  
Sodium Channel Blocking Agents/Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat simple partial seizure by both preventing the uptake of gamma-aminobutyric acid which prevents nerve activation as well as blocking the sodium channels which in turn block the conductance of neural impulses.

Target Products:

  • Topiramate
 
Headaches  
Tension Type  
Analgesics/Sedatives/Vasoconstrictive Agents
Therapeutics that treat tension type headaches by inhibiting the action of prostaglandins, constricting blood vessels in the brain thus reducing the pulsing action of blood in the cerebral arteries, and exerting a mild sedative effect.

Target Products:

  • Isometheptene/Dichloralphenazone/Acetaminophen
  • Duradrin (Isometheptene/Dichloralphenazone/Acetaminophen)
 
Vascular (Migraine)  
Acute Treatments  
Analgesics/Sedatives/Vasoconstrictive Agents
Therapeutics that treat migraine by inhibiting the action of prostaglandins, constricting blood vessels in the brain thus reducing the pulsing action of blood in the cerebral arteries, and exerting a mild sedative effect.

Target Products:

  • Duradrin (Isometheptene/Dichloralphenazone/Acetaminophen)
  • Isometheptene/Dichloralphenazone/Acetaminophen
 
Prophylactic Treatments  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat Migraine by inhibiting stimulation of beta adrenergic receptors.

Target Products:

  • Pliva Propranolol Hydrochloride
 
Neuromuscular Disorders
Multiple Sclerosis (MS)  
Adenosine Deaminase Inhibitors
Therapeutics that treat multiple sclerosis by inhibiting the transformation of deoxyadenosine into deoxyinosine, thereby impairing the proliferation of certain white blood cells.

Buyer Products:

  • Mylinax (Cladribine)
 
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that down regulates the antibody response of the immune system.

Buyer Products:

  • Rebif (Recombinant Interferon Beta-1a)
 
Topoisomerase II Inhibitors
Therapeutics that treat multiple sclerosis by inhibiting a key enzyme involved with cell division.

Buyer Products:

  • Novantrone (Mitoxantrone Hydrochloride)
 
Myasthenia Gravis (MG)  
Cholinesterase Inhibitors
Therapeutics that treat Myasthenia Gravis by maintaining the transmission of nerve impulses by inhibiting the enzyme that breaks down acetylcholine.

Target Products:

  • Pyridostigmine Bromide
 
Parkinson`s Disease (PD)  
Adjunctive Treatments  
Cholinergic Receptor Blocking Agents
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by blocking acetylcholine receptors on neurons.

Target Products:

  • Pliva Benztropine Mesylate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • JNK Inhibitor
  • MMP-12 Inhibitor
  • Mylinax (Cladribine)
 
Psychiatric Disorders  
Anxiety  
Generalized Anxiety Disorder (GAD)  
Antihistamines
Therapeutics that treat anxiety by blocking the action of histamines.

Target Products:

  • Pliva Hydroxyzine Hydrochloride
  • Hydroxyzine Pamoate
 
Dopamine Receptor Blocking Agents
Therapeutics that treat anxiety by blocking dopamine receptors.

Target Products:

  • Prochlorperazine Maleate
 
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Alprazolam Extended Release
  • Chlordiazepoxide Hydrochloride
  • Diazepam
 
Obsessive Compulsive Disorder (OCD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Anxiety by selectively preventing the removal of serotonin.

Target Products:

  • Pliva Sertraline Hydrochloride
  • Fluvoxamine Maleate
  • Fluoxetine Hydrochloride
 
Panic Disorder  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Alprazolam Extended Release
  • Clonazepam ODT
 
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat panic disorder by selectively preventing the removal of serotonin.

Target Products:

  • Pliva Sertraline Hydrochloride
 
Post-Traumatic Stress Disorder (PTSD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat post traumatic stress disorder by selectively preventing the removal of serotonin.

Target Products:

  • Pliva Sertraline Hydrochloride
 
Social Anxiety Disorder (SAD)  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat Social Anxiety Disorder by selectively preventing the removal of serotonin.

Target Products:

  • Pliva Sertraline Hydrochloride
 
Childhood/Adolescent Disorders  
Attention Deficit Disorder (ADD)/Attention Deficit Hyperactivity Disorder (ADHD)  
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving hyperactivity in children due to an abnormally short attention span.

Target Products:

  • Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate And Amphetamine Sulfate Tablets
  • Dextroamphetamine Sulfate Extended Release
 
Enuresis (Bedwetting)  
Antidiuretic Agents
Therapeutics that treat enuresis by suppressing the passing of urine.

Target Products:

  • Desmopressin Acetate
 
Eating Disorders  
Bulimia  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat eating disorders by selectively preventing the removal of serotonin.

Target Products:

  • Fluoxetine Hydrochloride
 
Mood Disorders  
Bipolar Disorders (Manic Depressive Disorders)  
Lithium-Based Agents
Therapeutics that treat bipolar disorders by decreasing the concentrations of neurotransmitters.

Target Products:

  • Lithium Carbonate Extended Release
 
Monoaminergic Antagonists
Therapeutics that treat bipolar disorder by blocking the serotonin and dopamine receptors.

Target Products:

  • Olanzapine
  • Risperidone
 
Depression  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat depression by selectively preventing the removal of serotonin.

Target Products:

  • Trazodone Hydrochloride
  • Pliva Sertraline Hydrochloride
  • Fluoxetine Hydrochloride
 
Tetracyclic Compounds
Therapeutics that treat depression by increasing the synaptic concentrations of norepinephrine.

Target Products:

  • Mirtazapine
 
Premenstrual Dysphoric Disorders  
Selective Serotonin Reuptake Inhibitors (SSRI)
Therapeutics that treat premenstrual dysphoric disorders by selectively preventing the removal of serotonin.

Target Products:

  • Pliva Sertraline Hydrochloride
 
Schizophrenia  
Dopamine Receptor Blocking Agents
Therapeutics that treat schizophrenia by blocking the dopamine receptors.

Target Products:

  • Prochlorperazine Maleate
 
Monoaminergic Antagonists
Therapeutics that treat schizophrenia by blocking the serotonin and dopamine receptors.

Target Products:

  • Olanzapine
  • Risperidone
 
Sleep Disorders  
Insomnia  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat insomnia by enhancing the inhibitory action of gamma-aminobutyric acid.

Target Products:

  • Zolpidem Extended Release
  • Diazepam
 
Narcolepsy  
Alpha Adrenergic Receptor Agonists
Therapeutics that treat narcolepsy by stimulating the adrenergic receptors, which causes nervous system stimulation.

Target Products:

  • Modafinil
 
Sympathomimetic Agents
Therapeutic members of the amphetamine group of sympathomimetic amines that treat the disorder involving hronic and sudden daytime sleepiness.

Target Products:

  • Dextroamphetamine Sulfate Extended Release
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Osteopontin
 
Obstetrics/Gynecology
Child Birth/Pregnancy  
Prevention (Contraception)  
Contraceptives (Birth Control)  
Estrogens
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Target Products:

  • Kelnor (Ethynodiol Diacetate/Ethinyl Estradiol)
 
Estrogens/Progestins
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Target Products:

  • Velivet (Desogestrel/Ethinyl Estradiol)
  • Portia (Levonorgestrel/Ethinyl Estradiol)
  • Enpresse (Levonorgestrel/Ethinyl Estradiol)
  • Kariva (Desogestrel/Ethinyl Estradiol)
  • Lessina (Levonorgestrel/Ethinyl Estradiol)
  • Nortrel (Ethinyl Estradiol/Norethindrone) 7/7/7
  • Duramed Seasonale (Levonorgestrel/Ethinyl Estradiol)
  • Sprintec/Tri-Sprintec (Norgestimate/Ethinyl Estradiol)
  • Aviane 28 (Levonorgestrel/Ethinyl Estradiol)
  • Cryselle (Norgestrel/Ethinyl Estradiol)
  • Duramed Nordette Tablets (Levonorgestrel/Ethinyl Estradiol)
  • Seasonique Extended Release (Levonorgestrel/Ethinyl Estradiol)
  • Loestrin Fe (Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate)
  • Junel (Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate)
  • Drospirenone/Ethinyl Estradiol
  • Lo Seasonale (Levonorgestrel/Ethinyl Estradiol)
  • Aranelle (Norethindrone/Ethinyl Estradiol)
  • Mircette (Desogestrel Ethinyl Estradiol)
  • Apri (Desogestrel/Ethinyl Estradiol)
 
Progestins
Contraceptive Therapeutics that are female sex hormone necessary for the development of the female reproductive system

Target Products:

  • Errin (Norethindrone)
  • Plan B Prescription (Levonorgestrel)
  • Norethindrone Acetate
  • Camila (Norethindrone)
  • Plan B OTC (Levonorgestrel)
 
Female Genital Disorders
Endometriosis  
Gonadotropin Inhibitors
Therapeutics that treat endometriosis by preventing the release of the pituitary gland hormone, gonadotropin.

Target Products:

  • Danazol
 
Infertility  
Complications  
Premature Ovulation  
Gonadotropin Releasing Hormone (GnRH) Antagonists
Therapeutics that prevent premature ovulation by blocking the action of gonadotropin releasing hormone, which can stimulate ovulation.

Buyer Products:

  • Cetrotide (Cetrorelix Acetate)
 
Hormonal Treatments  
Gonadotropins
Therapeutics that treat difficulties in conceiving by stimulating sex hormone secretion from the female gonads.

Buyer Products:

  • Ovidrel/Ovidrel Pre-Filled Syringe (Choriogonadotropin Alfa)
  • Luveris (Lutropin alfa)
 
Ovulation Stimulating Agents
Therapeutics that treat infertility by stimulating the ovaries to release a mature egg.

Buyer Products:

  • Gonal-F (Follitropin Alfa)
  • Gonal-F Pen (Fllitropin Alfa Injection)
  • Serophene (Clomiphene Citrate)
 
Progestins
Therapeutics that treat female disorders characterized by the inability to achieve pregnancy or carry a pregnancy to term by increasing progesterone level in the body to induce uteran conditions favorable to conception and pregnancy.

Buyer Products:

  • Crinone (Progesterone Gel)
 
Ovarian  
Hypogonadism  
Hormonal Treatments  
Estrogens
These are female sex hormones.

Target Products:

  • Estradiol
  • Estropipate
 
Vulvovaginal  
Atrophy  
Hormonal Treatments  
Estrogens
Therapeutics that treat disorders characterized by thinning of the vaginal walls with the female sex hormone estrogen.

Target Products:

  • Duramed Cenestin (Synthetic Conjugated Estrogens, A)
  • Bijuva Cream (Synthetic Conjugated Estrogens, A)
  • Estradiol
  • Estropipate
 
Estrogens/Progestins
Therapeutics that treat disorders characterized by thinning of the vaginal walls with a combination of the female sex hormones estrogen and progestin.

Target Products:

  • Duramed Prefest (17-Estradiol/Norgestimate)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of female reproductive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Hyperglycosylated r-FSH
  • Anastrozole
  • Oxytocin Receptor Antagonist
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of female reproductive disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • Prostanoid FP Receptor Antagonist
 
Oncology
Breast Cancer  
Localized  
Antimetabolite Agents  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat and manage breast cancers by inhibiting an enzyme needed for the synthesis of DNA.

Target Products:

  • Trexall (Methotrexate)
  • Methotrexate Sodium
 
Estrogen Receptor Blocking Agents
Therapeutics that treat and manage breast cancers by blocking the uptake of estrogen which has been implicated in causing breast cancer.

Target Products:

  • Tamoxifen Citrate
 
Progestins
Therapeutics that treat and manage breast cancers by providing progestins which in turn results in decreased estrogen levels.

Target Products:

  • Megestrol Acetate
 
Metastatic  
Estrogen Receptor Blocking Agents
Therapeutics that treat and manage breast cancer by blocking the uptake of estrogen which has been implicated in causing breast cancer.

Target Products:

  • Tamoxifen Citrate
 
Dermatology  
Malignant Melanoma  
Ribonucleotide Reductase Inhibitors
Therapeutics that treat and manage cancers of pigment cells in the epidermis and dermis by interfering with DNA synthesis.

Target Products:

  • Hydroxyurea
 
Digestive System  
Colon Cancer/Colorectal Cancer  
Palliative Agents  
Folic Acid Derivatives
Therapeutics that treat colorectal cancers by helping to reduce toxicity by allowing DNA/RNA/Protein synthesis to occur even when the pathway has been blocked by folic acid antagonists.

Target Products:

  • Leucovorin
 
Head/Neck Cancer  
Localized  
Antimetabolite Agents  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat and manage primary tumors of the head and neck by inhibiting the production of DNA.

Target Products:

  • Methotrexate Sodium
  • Trexall (Methotrexate)
 
Ribonucleotide Reductase Inhibitors
Therapeutics that treat and manage primary tumors of the head and neck by interfering with DNA synthesis.

Target Products:

  • Hydroxyurea
 
Hematology
Leukemia (White Blood Cell Cancer)  
Lymphoid  
Acute  
Lymphocytic  
Antimetabolite Agents  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat and manage rapidly progressing cancers of lymphocytic cells by inhibiting an enzyme needed for the synthesis of DNA.

Target Products:

  • Trexall (Methotrexate)
  • Methotrexate Sodium
 
Meningeal  
Antimetabolite Agents  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat and manage neoplasm's of immature immune cells that have spread to the brain by inhibiting an enzyme needed for the synthesis of DNA.

Target Products:

  • Methotrexate Sodium
  • Trexall (Methotrexate)
 
Myeloid  
Chronic  
Myelogenous (CML)  
Ribonucleotide Reductase Inhibitors
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by interfering with DNA synthesis.

Target Products:

  • Hydroxyurea
 
Lymphoma (Lymphatic Cancer)
Cutaneous T-Cell (CTCL)  
Mycosis Fungoides  
Monoclonal Antibodies
Therapeutics that treat T-cell lymphomas by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • HuMax-CD4 (Zanolimumab)
 
Non-Hodgkin`s Lymphoma (NHL)  
Antimetabolite Agents  
Dihydrofolate Reductase Inhibitors
Therapeutics that treat and manage lymphomas of B-cells and T-cells by inhibiting the production of DNA.

Target Products:

  • Trexall (Methotrexate)
  • Methotrexate Sodium
 
Multiple Myeloma (Plasma Cell Cancer)  
Immunomodulatory Agents
Therapeutics that treat multiple myeloma by stimulating the immune system.

Target Products:

  • Thalidomide
 
Musculoskeletal System  
Bone Cancer  
Osteosarcoma  
Palliative Agents  
Folic Acid Derivatives
Therapeutics that are meant to reduce the toxicity of treating malignant tumors of the bone by allowing DNA/RNA/Protein synthesis to occur even when the pathway has been blocked by folic acid antagonists.

Target Products:

  • Leucovorin
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • Atacicept/TACI-Ig
  • MT201 (Adecatumumab)
  • R763 (Aurora Kinase Inhibitor)
  • HuMax-CD4 (Zanolimumab)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Buyer Products:

  • IKK2 Inhibitor
 
Urology  
Endometrial Cancer  
Localized  
Progestins
Therapeutics that treat and manage cancer of the endometrial cells lining the uterus by providing a female sex hormone necessary for the development of the female reproductive system.

Target Products:

  • Megestrol Acetate
 
Kidney Cancer (Renal Cell Carcinoma)  
Metastatic  
Hormonal Treatments  
Progestins
Therapeutics that treat and manage renal cancers that have spread beyond their original tumor site by supplying a female sex hormone necessary for the development of the female reproductive system.

Target Products:

  • Megestrol Acetate
 
Ovarian Cancer  
Adenocarcinoma  
Ribonucleotide Reductase Inhibitors
Therapeutics that treat and manage cancer of cells lining the ovary by interfering with DNA synthesis.

Target Products:

  • Hydroxyurea
 
Prostate Cancer  
Localized  
Androgen Receptor Blockers
Therapeutics that treat prostate cancer by blocking androgen receptors. This limits the action of male hormones which have been implicated as a causative agent in prostate cancer.

Target Products:

  • CyPat (Cyproterone)
 
Metastatic  
Androgen Receptor Blockers
Therapeutics that treat and manage prostate cancers that have spread beyond their original tumor site by binding to the androgen receptors in target tissue thus inhibiting the action of androgens.

Target Products:

  • Flutamide
 
Ophthalmology  
Degenerative Disorders  
Glaucoma  
Carbonic Anhydrase Inhibitors
Therapeutics that decrease the formation of the fluid of the eye.

Target Products:

  • Duramed Diamox (Acetazolamide)
 
Irritation/Inflammation  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Pliva Ketorolac Tromethamine
 
Pain Management  
Anesthesia  
General (Systemic)  
Adjunctive  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that result in anesthesia by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Target Products:

  • Diazepam
 
Narcotics  
Analgesics/Opioids
Therapeutics that treat pain by binding to certain nervous system receptors which alters the both the perception of pain as well as the emotional response to pain.

Target Products:

  • Acetaminophen/Codeine
  • Oxycodone/Acetaminophen
 
Opioids
Therapeutics that treat pain by binding to certain nervous system receptors which alter both the perception of pain as well as the emotional response to pain.

Target Products:

  • Meperidine Hydrochloride
  • Pliva Tramadol Hydrochloride
  • Oral Transmucosal Fentanyl Citrate [C-II]
 
Non-Narcotics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Target Products:

  • Pliva Diclofenac Sodium
  • Pliva Naproxen Sodium
 
Skeletal Muscle Relaxing Agents
Therapeutics that treat pain by depressing specific synaptic reflexes preferentially.

Target Products:

  • Chlorzoxazone
  • Pliva Cyclobenzaprine HCL
 
Respiratory System  
Lower Respiratory Tract Disorders (Lung Disorders)  
Asthma  
Prophylactic Treatments  
Phosphodiesterase Inhibitors (PDE Inhibitors)
Therapeutics that inhibit the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in relaxing smooth muscles in the lungs.

Target Products:

  • Pliva Theophylline
 
Bronchitis  
Prophylactic Treatments  
Phosphodiesterase Inhibitors (PDE Inhibitors)
Therapeutics that inhibit the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in relaxing smooth muscles in the lungs.

Target Products:

  • Pliva Theophylline
 
Emphysema  
Prophylactic Treatments  
Phosphodiesterase Inhibitors (PDE Inhibitors)
Therapeutics that inhibit the break down of phosphodiesters thereby increasing levels of Nitric Oxide which help in relaxing smooth muscles in the lungs.

Target Products:

  • Pliva Theophylline
 
Upper Respiratory Tract Disorders  
Coughs/Colds  
Antihistamines
Therapeutics that inhibit the inflammation by blocking the action of histamines on tissues.

Target Products:

  • Diphenhydramine Hydrochloride
  • Fexofenadine Hydrochloride (12 Hours Extended Release)
 
Antihistamines/Antiserotonins
Therapeutics that inhibit inflammation by blocking the action of histamines and serotonins on tissues.

Target Products:

  • Pliva Cyproheptadine HCl
 
Antitussives
Therapeutics that relieve or prevent coughs.

Target Products:

  • Pliva Benzonatate
 
Decongestants/Expectorants/Opioids
Therapeutics that treat coughs and colds by reducing mucous build up, suppressing coughs and help in ejection of mucous.

Target Products:

  • MedTuss HD Elixir C-III
 
Steroidal Anti-Inflammatory Drugs (SAID)
Therapeutics that counteract or suppress the inflammation in the upper respiratory tract with steroidal compounds.

Target Products:

  • Triamcinolone Acetonide Nasal Spray
 
Surgery  
Cardiovascular System  
Thrombosis  
Thrombin Inhibitors
Therapeutics that thin the blood of a blocked blood vessel during surgery by blocking an enzyme involved in the clotting process.

Target Products:

  • Warfarin Sodium
 
General  
Complications  
Nausea/Vomiting  
Serotonin Receptor Antagonists
Therapeutics that prevent or treat post surgical nausea and vomiting by blocking the receptors that bind serotonin, a neurotransmitter.

Target Products:

  • Ondansetron Hydrochloride
 
Musculoskeletal System  
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat vascular obstructions due to platelets and cell matter by blocking an enzyme involved in the clotting process.

Target Products:

  • Warfarin Sodium
 
Ophthalmology  
Ocular Inflammation  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation resulting from surgical procedures to remove cataracts by preventing cyclooxygenase activity.

Target Products:

  • Pliva Ketorolac Tromethamine
 
Toxicology  
Substance Abuse  
Withdrawal  
Alcohol  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Target Products:

  • Chlordiazepoxide Hydrochloride
  • Diazepam
 
Opioid Antagonists
Therapeutics that treat alcohol dependence by blocking the effect of opioids.

Target Products:

  • Naltrexone Hydrochloride
  • Duramed ReVia (Naltrexone Hydrochloride)
 
Narcotics  
Opioid Antagonists
Therapeutics that treat narcotic addiction by blocking the effect of opioids.

Target Products:

  • Duramed ReVia (Naltrexone Hydrochloride)
  • Naltrexone Hydrochloride
 
Transplantation  
Heart  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that help manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • Pliva Cyclosporine
 
Hepatic (Liver)  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • Pliva Cyclosporine
 
Renal (Kidney)  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Target Products:

  • Pliva Cyclosporine
 
Urology
Male Genital Disorders
Prostate  
Benign Prostate Hyperplasia (BPH)  
5-Alpha Reductase Inhibitors
Therapeutics that inhibit the transformation of testosterone into dihydrotestosterone (DHT), a substance that causes enlargement of the prostate.

Target Products:

  • Finasteride
 
Alpha Adrenergic Receptor Blocking Agents (Alpha Blockers)
Therapeutics that increase blood flow by acting on the alpha adrenergic receptors thus causing the smooth muscle in the prostate to relax and decreasing the constriction on the urinary tract.

Target Products:

  • Pliva Doxazosin Mesylate
 
Testicular  
Hypogonadism  
Gonadotropins
Therapeutics that treat hypogonadism by providing gonadotropins which stimulate sex hormone secretion from the gonads.

Buyer Products:

  • Gonal-F (Follitropin Alfa)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Target Products:

  • Oxybutynin TVR
 
Urological Disorders  
Bladder  
Neurogenic Bladder Disease  
Anticholinergic Agents
Therapeutics that block the actions of choline and other cholinergic agents.

Target Products:

  • Pliva Oxybutynin Chloride
 
Cholinergic Agents
Therapeutics that treat bladder dysfunction arising from the malfunction of autonomic nerves that control bladder function with choleinergic agents.

Target Products:

  • Pliva Bethanechol Chloride
 
Urinary Frequency/Urge Incontinence  
Anticholinergic Agents
Therapeutics that treat the inability to control urinary excretory functions by blocking the actions of choline and other cholinergic agents.

Target Products:

  • Pliva Oxybutynin Chloride
 
Kidney (Renal)  
Chronic Renal Failure (CRF)  
Complications  
Edema  
Potassium Sparing Diuretic Agents/Thiazide Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissue by increasing the excretion of sodium and water, but not potassium in urine.

Target Products:

  • Triamterene/Hydrochlorothiazide
 
Weight Management
Anorexia (Appetite Loss)  
Progestins
Therapeutics that treat weight loss and other conditions arising from the uncontrolled loss of appetite by administration of hormone progestins.

Target Products:

  • Megestrol Acetate
 
Cachexia
Anabolic Testosterone Analogs
Therapeutics containing a class of compounds that boost the body's metabolism and help in gaining weight.

Target Products:

  • Oxandrolone
 
Growth Hormones
Therapeutics that treat weight loss usually resulting from cancer and/or AIDS treatment by providing a hormone which stimulates body growth and development.

Buyer Products:

  • Serostim (Somatropin)
 
Progestins
Therapeutics that treat cachexia by providing female hormones.

Target Products:

  • Megestrol Acetate
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PTP 1b Inhibitor
 
Medical Devices
Drug Delivery  
Percutaneous (Subcutaneous/Intramuscular/Intravenous)  
Syringes  
Specialty  
Prefillable
Syringes designed for the advanced loading and storage of medications prior to use

Buyer Products:

  • easypod
 
Transdermal  
Needle Free Injection Systems
Medical devices which generate a highly-pressurized jet of medication for direct delivery through the skin; also known as jet-injectors

Buyer Products:

  • SeroJet
  • one.click
  • Rebiject/Rebiject II
  • cool.click
 
General Surgery  
Invasive  
Transplantation  
Organ Preservation
Devices used to preserve organs prior to transplantation.

Target Products:

  • ViaSpan (Belzer UW)
 
Obstetrics/Gynecology  
Treatment  
Procedure Specific  
Contraception  
Intrauterine Devices (IUD)
IUDs, or Intrauterine devices, are a form of birth control used by women.

Target Products:

  • ParaGard T 380A
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
Novartis AG (ADR) n/a 132,695.720 24.32 16.91 3.48 3.56 3.28
Wyeth n/a 75,840.119 17.51 16.02 3.63 3.44 7.06
Eli Lilly & Co. n/a 67,328.131 28.81 17.46 4.16 3.79 7.38
Teva Pharmaceutical Industries Ltd (ADR) n/a 23,784.954 12.54 18.38 2.70 2.63 17.54
Shire plc (ADR) n/a 12,878.614 39.05 36.38 6.73 5.78 6.63
Par Pharmaceutical Companies, Inc n/a 1,016.836 n/a 18.55 2.00 1.36 2.92
Savient Pharmaceuticals, Inc. n/a 727.512 15.00 -12.46 16.37 n/a 4.31
Buyer
  Pfizer Inc. n/a 192,581.140 10.35 12.73 3.92 4.03 6.86
Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
Target
  Johnson & Johnson n/a 183,699.702 17.80 15.53 3.32 3.00 15.70
Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
Novartis AG (ADR) n/a 132,695.720 24.32 16.91 3.48 3.56 3.28
Wyeth n/a 75,840.119 17.51 16.02 3.63 3.44 7.06
Eli Lilly & Co. n/a 67,328.131 28.81 17.46 4.16 3.79 7.38
Amgen, Inc. n/a 62,667.219 20.48 13.09 4.25 4.15 13.05
Bristol Myers Squibb Co. n/a 59,927.581 38.39 21.43 3.38 3.05 16.40
Teva Pharmaceutical Industries Ltd (ADR) n/a 23,784.954 12.54 18.38 2.70 2.63 17.54
Shire plc (ADR) n/a 12,878.614 39.05 36.38 6.73 5.78 6.63
Cephalon, Inc. n/a 5,380.536 24.86 19.95 2.92 3.00 31.12
Mylan Laboratories Inc. n/a 4,356.420 12.58 12.41 3.01 2.80 4.81
Warner Chilcott Ltd. n/a 4,279.671 n/a 18.18 5.31 5.04 n/a
Watson Pharmaceuticals, Inc. n/a 3,246.100 n/a 24.58 1.45 1.23 31.54
Dr. Reddy's Laboratories Limited (ADR) n/a 2,514.047 18.63 15.28 1.93 1.83 n/a
Perrigo Company n/a 1,868.941 27.78 22.27 1.31 1.28 5.19

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Bioject Medical Technologies Inc. 27.00% 19.247 n/a n/a 1.78 n/a 3.86
Rigel Pharmaceuticals, Inc. 14.90% 286.415 n/a -4.84 8.56 9.06 3.28
Vernalis plc (ADR) 4.00% 399.459 n/a n/a 12.26 n/a n/a
Regeneron Pharmaceuticals, Inc. n/a 1,640.404 n/a -14.33 26.89 19.94 8.34
ZymoGenetics, Inc. n/a 1,022.986 n/a -6.67 44.15 32.60 4.85
Taleo Corporation n/a 478.282 n/a 128.29 4.62 3.80 6.42
Ness Technologies, Inc n/a 468.258 16.04 12.17 0.95 0.83 3.60
XOMA Limited n/a 434.514 n/a -11.29 14.73 7.71 n/a
Caliper Life Sciences Inc. n/a 236.790 n/a -12.05 2.08 1.65 12.68
Columbia Laboratories Inc. n/a 120.294 n/a n/a 6.92 n/a n/a
TorreyPines Therapeutics Inc. n/a 112.261 n/a n/a 11.40 n/a 2.76
Micromet Inc. n/a 77.495 n/a -2.51 2.81 5.28 8.86
Owen Mumford Ltd. n/a n/a n/a n/a n/a n/a n/a
Target
  Mack-Cali Realty Corp. n/a 3,084.120 23.97 13.30 3.95 4.63 1.75
Indevus Pharmaceuticals n/a 548.187 n/a -8.82 10.66 8.04 n/a
Common Sense Ltd. n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
Abbott Laboratories n/a 91,543.593 59.09 20.96 4.05 4.04 n/a
Amgen, Inc. n/a 62,667.219 20.48 13.09 4.25 4.15 13.05
Akzo Nobel N.V. (ADR) n/a 23,296.279 14.08 16.61 1.27 1.54 5.13
Biogen Idec Inc. n/a 15,869.459 70.30 18.88 5.69 5.17 4.50
Columbia University n/a n/a n/a n/a n/a n/a n/a
Target
  McKesson Corporation 27.00% 18,402.914 20.16 19.02 0.20 0.18 5.88
Cardinal Health, Inc. 15.00% 27,606.223 20.45 20.84 0.32 0.31 7.97
AmerisourceBergen Corp. 11.00% 9,806.312 19.89 19.77 0.15 0.15 7.05
Walgreen Company 10.00% 45,622.784 23.22 21.90 0.89 0.84 4.32
Warner Chilcott Ltd. n/a 4,279.671 n/a 18.18 5.31 5.04 n/a
Indevus Pharmaceuticals n/a 548.187 n/a -8.82 10.66 8.04 n/a
Government - United States n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Abbott Laboratories n/a 91,543.593 59.09 20.96 4.05 4.04 n/a
Teva Pharmaceutical Industries Ltd (ADR) n/a 23,784.954 12.54 18.38 2.70 2.63 17.54
Akzo Nobel N.V. (ADR) n/a 23,296.279 14.08 16.61 1.27 1.54 5.13
Buyer
  Pfizer Inc. n/a 192,581.140 10.35 12.73 3.92 4.03 6.86
Roche Holding Ltd. (ADR) n/a 160,264.110 24.51 21.03 4.59 4.01 6.88
Abbott Laboratories n/a 91,543.593 59.09 20.96 4.05 4.04 n/a
AstraZeneca plc (ADR) n/a 81,935.278 13.26 13.57 3.01 2.92 8.66
Genentech, Inc. n/a 81,388.978 33.94 29.34 8.03 6.96 9.71
Wyeth n/a 75,840.119 17.51 16.02 3.63 3.44 7.06
Amgen, Inc. n/a 62,667.219 20.48 13.09 4.25 4.15 13.05
Bayer AG (ADR) n/a 52,907.745 10.05 16.01 1.28 1.16 n/a
Teva Pharmaceutical Industries Ltd (ADR) n/a 23,784.954 12.54 18.38 2.70 2.63 17.54
Akzo Nobel N.V. (ADR) n/a 23,296.279 14.08 16.61 1.27 1.54 5.13
Target
  Abbott Laboratories n/a 91,543.593 59.09 20.96 4.05 4.04 n/a
Teva Pharmaceutical Industries Ltd (ADR) n/a 23,784.954 12.54 18.38 2.70 2.63 17.54
Akzo Nobel N.V. (ADR) n/a 23,296.279 14.08 16.61 1.27 1.54 5.13
Shire plc (ADR) n/a 12,878.614 39.05 36.38 6.73 5.78 6.63
Cephalon, Inc. n/a 5,380.536 24.86 19.95 2.92 3.00 31.12
King Pharmaceuticals, Inc. n/a 5,229.016 14.76 12.45 2.59 2.53 4.46
Warner Chilcott Ltd. n/a 4,279.671 n/a 18.18 5.31 5.04 n/a
Par Pharmaceutical Companies, Inc n/a 1,016.836 n/a 18.55 2.00 1.36 2.92
Savient Pharmaceuticals, Inc. n/a 727.512 15.00 -12.46 16.37 n/a 4.31
Indevus Pharmaceuticals n/a 548.187 n/a -8.82 10.66 8.04 n/a
Paladin Labs Inc. n/a 176.576 33.68 n/a 4.04 n/a 3.74
Common Sense Ltd. n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 2,498.4 1,721.5 4,219.9
Other Revenue 306.6 145.9 452.5
Total Revenue 2,804.9 1,867.4 4,672.4
Cost of Revenue 298.0 799.2 1,097.2
SG&A Expense 954.3 540.4 1,494.7
Depreciation & Amortization 0.0 0.0 0.0
Research & Development 560.5 205.2 765.6
Interest Expense 0.0 0.0 0.0
Other Operating Expense 255.6 0.0 255.6
Unusual Expense (Income) 0.0 382.2 382.2
Total Expenses 2,068.4 1,927.0 3,995.3
Operating Income 736.6 -59.5 677.0
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng 30.0 -40.8 -10.7
Other, Net 0.0 -55.1 -55.1
Income Before Taxes 766.6 -155.4 611.2
Income Taxes 31.0 87.7 118.7
Income After Taxes 735.6 -243.1 492.5
Minority Interest (IS) -0.2 -0.9 -1.1
Net Income - Excl. Xord. Items 735.4 -244.0 491.4
Discontinued Operations 0.0 -0.3 -0.3
Net Income - Incl. Xord. Items 735.4 -244.3 491.1
Income Avail. to Common 735.4 -244.3 491.1
Share Items
Basic Avg. Shares Outstanding 595.4 106.7 702.1
Basic EPS - Excl. Xord. Items 1.24 n/a 0.70
Basic EPS - Incl. Xord. Items 1.24 n/a 0.70
Full Dilution Adjustment 10.8 0.0 10.8
Fully Diluted Shares Outstanding 602.2 108.0 710.2
F.D. EPS - Excl. Xord. Items 1.22 n/a 0.69
F.D. EPS - Incl. Xord. Items 1.22 n/a 0.69
Balance Sheet
Assets
Cash and Equivalents 1,734.9 194.7 1,929.6
ST Investments 351.2 647.5 998.6
Accounts Receivable 439.5 512.1 951.7
Inventory 254.9 428.5 683.4
Prepayments and Advances 788.3 40.8 829.1
Other Current Assets 0.0 129.1 129.1
Current Assets 3,568.9 1,952.7 5,521.6
PPE 0.0 1,251.0 1,251.0
Accum D&A 0.0 -216.8 -216.8
PPE, Net 873.5 1,034.2 1,907.8
Goodwill & Intangibles 317.3 1,714.3 2,031.6
Long Term Investments 474.9 11.8 486.7
Other Assets 0.0 0.0 0.0
Other LT Assets 366.8 86.4 453.2
Total Assets 5,601.4 4,799.4 10,400.8
Liabilities
Accounts Payable 421.9 138.7 560.6
Payable/Accrued 0.0 0.0 0.0
Accrued Expenses 0.0 262.9 262.9
ST Debt 776.7 0.0 776.7
Curr Port of LTD & Cap Lease Oblg 0.0 650.9 650.9
Other (Current) Liabilities 298.3 17.4 315.7
Current Liab. 1,496.9 1,069.9 2,566.8
LT Debt 28.0 1,879.9 1,907.8
Total LT Debt 28.0 1,879.9 1,907.8
Minority Interest (BS) 0.9 39.0 40.0
Deferred Taxes 5.6 211.3 216.9
Other LT Liab. 387.1 100.4 487.5
Total Liabilities 1,918.5 3,300.6 5,219.0
Shareholders Equity
Common Stock 237.1 1.1 238.2
Additional Paid in Capital 817.7 624.9 1,442.6
Retained Earnings 2,571.7 889.6 3,461.3
Treasure Stock 0.0 -100.7 -100.7
Other Equity 56.3 84.0 140.3
Total Equity 3,682.9 1,498.8 5,181.7
Total Liab. & Equity 5,601.4 4,799.4 10,400.8
Shares Outstanding 612.5 106.8 719.3
Cash Flow
Operating Cash Flow
CF Net Income 735.6 -66.2 669.4
CF Depreciation 126.5 190.7 317.2
CF Deferred Taxes 0.0 2.4 2.4
Other Non-Cash Items 101.3 469.9 571.3
Change in Working Capital -73.6 -78.9 -152.5
Total Cash From Operating Activities 889.8 517.9 1,407.7
Investing Cash Flow (not calculated)
Capital Expenditures -199.7 -104.2 -303.9
Other Investing Cash Flows 742.9 -2,657.3 -1,914.4
Total Cash From Investing Activities 543.2 -2,761.5 -2,218.3
Financing Cash Flow (not calculated)
Dividends Paid -117.1 0.0 -117.1
Purchase Or Sale of Stock 41.8 62.8 104.6
Purchase and Retirement of Debt 58.4 2,255.1 2,313.6
Other Financing Cash Flow -34.0 16.4 -17.6
Total Cash From Financing Activities -58.6 2,334.4 2,275.8
Exchange Rate Effects 1.7 3.3 5.1
Net Change in Cash 1,376.1 94.2 1,470.2
Cash Taxes Paid 108.7 179.5 288.2
Cash Interest Paid 6.5 6.6 13.1