Summary

Other Scenarios:

Buyer: Roche Holding AG (RHHBY) Last Price: 42.06 Market Cap.: 145.12B
Target: Dendreon Corp (DNDN) Last Price: 9.06 Market Cap.: 1.35B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
Healthcare 731
Biopharmaceuticals 334
Healthcare Services   122
Medical Devices   177
Outsourced Biomedical Services   39
Scientific Products   23
Technology   806
Information Technology (IT) Services   105
Software   247

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business
Buyer (Total: 301)
  • Xolair (Omalizumab)
  • Dilatrend (Carvedilol)
  • Demadex (Toresmide)
  • TNKase/Metalyse (Tenecteplase)
Target (Total: 6)
  • DN24-02 (Immunotherapy)
  • D-3263 (Trp-p8 Small Molecule)
  • Provenge (Sipuleucel-T)
  • Carcinoembryonic Antigen (CEA) Vaccine
Buyer
  • Quantitative Diagnostics Laboratories, Inc. (QDL)
  • Verum Diagnostica GmbH
  • Roche Diagnostics - Roche/Hitachi 902/912
  • Roche Diagnostics - Cobas 8000 Modular Analyser Series
Target

n/a

Business Relationship Summary:

Top Key Suppliers

Top Key Customers
Buyer (Total: 64)
  • Synageva BioPharma Corp (GEVA)
  • PDL Biopharma Inc (PDLI)
  • Seattle Genetics Inc (SGEN)
  • Alnylam Pharmaceuticals Inc (ALNY)
Target (Total: 7)
  • Bayer AG (BAYRY)
  • Fuji Film Holdings KK (FUJIY)
  • Hemacare Corp (HEMA)
  • New York Blood Center
Buyer (Total: 27)
  • Novartis SA (NVS)
  • Regeneron Pharmaceuticals Inc (REGN)
  • Gen-Probe Inc (GPRO)
  • Ironwood Pharmaceuticals Inc (IRWD)
Target (Total: 1)
  • Government - United States

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 80,653 1,497
Revenue Per Employee 664,913.5 132,775.3
Total Revenue 20,860.0 82.1
Total Expenses 14,866.0 172.6
Other Revenue n/a 0.1
Cost of Revenue 5,844.0 60.0
SG&A Expense 5,090.0 95.3
Research & Development 4,200.0 17.3
Other Operating Expense -786.0 n/a
Operating Income 5,994.0 -90.5
Unusual Income 507.0 -0.1
LT Debt to Capital 65.98 67.05
Fwd P/E 10.28 -3.81
Fwd P/Rev 3.03 3.59
Book Value 12,095.0 279.5
Curr Portion of LTD/Cap Lease 3,394.0 4.9

Individual Company Summary

Focused

Buyer

Focused (): Healthcare > Biopharmaceuticals

Target

Focused (): Healthcare > Biopharmaceuticals > Oncology

Business Description

Buyer

Roche Holding AG is a Switzerland-based pharmaceuticals and diagnostics company. It belongs to the Roche Group that operates through subsidiaries and associated companies around the world. It discovers, develops and provides diagnostic and therapeutic products and services from early detection and prevention of diseases to diagnosis, treatment and treatment monitoring. Roche has two divisions: Pharmaceuticals and Diagnostics. Pharmaceuticals are divided into three sub-divisions: Roche Pharmaceuticals, Genentech and Chugai. It operates in the United States, Western Europe, Japan, CEMAI (Central and Eastern Europe, Middle East, Africa, Central Asia, Indian Subcontinent), Latin America, Asia-Pacific and Other regions. Diagnostics include five sub-divisions: Applied Science, Diabetes Care, Molecular Diagnostics, Tissue Diagnosis and Professional Diagnostics. It is structured into five segments: North America; Asia-Pacific; EMEA (Europe, Middle East and Africa); Latin America and Japan.

Target

Dendreon Corporation (Dendreon) is a biotechnology company focused on the discovery, development and commercialization of therapeutics that may improve cancer treatment options for patients. The Company?s product portfolio includes active cellular immunotherapy and small molecule product candidates to treat a range of cancers. On April 29, 2010, the United States Food and Drug Administration (FDA) licensed PROVENGE (sipuleucel-T), its autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic, metastatic, castrate-resistant (hormone-refractory) prostate cancer. Commercial sale of PROVENGE began in May 2010. Dendreon owns worldwide rights for PROVENGE. Other product candidates it has under development include its investigational active cellular immunotherapy, DN24-02, directed against HER2/neu for the treatment of patients with bladder, breast, ovarian and other solid tumors expressing HER2/neu.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 80.52 49.38
Operating Margin % 52.74 -70.08
Quick Ratio 1.3 6.25
Current Ratio 1.74 7.35
Coverage Ratio n/a n/a
Total Assets 61,576.0 942.0
Return on Equity % 354.76 -470.67
Return on Assets % 69.68 -139.67
Cash+ ST Inv. Per Share 13.29 3.37
Total Debt 26,853.0 573.8
Total Debt to Equity % 222.02 205.28
Total Debt to Tangible Equity % n/a 205.28
Debt to Asset % 43.61 60.92

Product Summary

Sector Buyer Target
Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
  
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
  
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
  
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
  
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
  
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
  
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
  
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
  
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
  
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
  
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
  
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
  
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
  
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
  
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
  
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
  
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes therapeutics that treat and manage weight disorders.
  
Wound Management
The Wound Management Subsector includes therapeutics that treat cuts, abrasions, and burns from trauma or diseases.
  
Healthcare Services  
Patient Care
The Patient Care Subsector is comprised of companies that provide services to patients for the diagnosis, treatment, and/or prevention of diseases and injuries.
  
Medical Devices  
Clinical Diagnostics
The Clinical Diagnostics Subsector includes medical devices that analyze human body specimens within a medical setting. These devices, including equipment, biological and chemical reagents are primarily used for the diagnosis of diseases.
  
Drug Delivery
The Drug Delivery Subsector includes medical devices that facilitate the delivery of medications through different anatomical entryways, including blood vessels, skin, the mouth, and the lungs. Common devices in this sector include vascular access catheters, needles, implants, and inhalers.
  
Outsourced Biomedical Services  
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Buyer Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
  
Bioanalytical Services
The Bioanalytical Services Subsector includes outsourced services that utilize bioanalytical instruments to analyze biological samples.
  
Drug Discovery Services
The Drug Discovery Services Subsector includes companies that provide biopharmaceutical companies with novel biological targets and drug leads.
  
Scientific Products  
Analytical Instruments
The Analytical Instruments Subsector includes scientific products that determine the quantitative and qualitative nature of chemical and biochemical samples.
  
Bioanalytical Instruments
The Bioanalytical Subsector includes scientific products, devices, apparatuses, and consumables used to determine the quantitative and qualitative nature of a biological samples.
  
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting
Information technology related to consulting services designed to improve a client company's operating efficiency, and business capabilities through the expert application of information technology resources and best practices. These services can be delivered on a project-by-project basis, or via an on-going relationship.
  
Software  
Industry-Specific
Software that has functionality specific to a vertical industry.
  

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
Healthcare
Biopharmaceuticals
Allergies  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for treatment of allergic reactions in early stages of clinical research where human subject is involved.

Buyer Products:

  • Xolair (Omalizumab)
  
Upper Respiratory  
Monoclonal Antibodies
Therapeutics that treat allergic reactions by specifically binding and inhibiting inflammatory substances.

Buyer Products:

  • Xolair (Omalizumab)
  
Cardiovascular System  
Heart Disorders  
Heart Failure (HF)  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat the ineffective pumping of the heart by blocking beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Dilatrend (Carvedilol)
  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Demadex (Toresmide)
  
Myocardial Infarction (MI)  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Dilatrend (Carvedilol)
  
Thrombolytic Agents
Therapeutics that treat the ineffective pumping of the heart by dissolving blood clots in blood vessels.

Buyer Products:

  • TNKase/Metalyse (Tenecteplase)
  • Activase (Alteplase)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • RG1512 (P-Selectin Monoclonal Antibody)
  • RG7418 (Anti-oxLDL Antibody)
  • BO-653 (Antioxidant)
  • AXV034343 (Endothelin A Receptor Antagonist)
  
Vascular Disorders  
Hypertension  
Loop Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Demadex (Toresmide)
  
Stroke  
Thrombolytic Agents
Therapeutics that prevent or treat damage to nerve cells of the brain by dissolving blood clots in blood vessels.

Buyer Products:

  • Activase (Alteplase)
  
Thromboembolism  
Thrombolytic Agents
Therapeutics that treat obstructions of blood vessels by dissolving blood clots.

Buyer Products:

  • Activase (Alteplase)
  • TNKase/Metalyse (Tenecteplase)
  
Dermatology  
Lesion/Scaling Disorders  
Chronic Urticaria  
Monoclonal Antibodies
Therapeutics that treat chronic urticaria by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Xolair (Omalizumab)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skin disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
  • BAL2299 (Nuclear Receptor Modulator)
  
Digestive System  
Gastrointestinal Tract Disorders  
Gastroesophageal Disorders  
Nausea/Vomiting  
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Buyer Products:

  • Kytril (Granisetron Hydrochloride)
  
Liver Disorders  
Cirrhosis  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that prevent edema by excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Demadex (Toresmide)
  
Hepatitis  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  • Pegasys (Pegylated Interferon Alfa-2a)
  
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections by preventing viral replication, stimulating the immune system to also fight the virus, and inhibits replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1270 (Levovirin)
  • RG7413 (Anti-Beta 7 Monoclonal Antibody)
  • Serine Palmitoyl Transferase Inhibitor
  • RG7432 (Nucleoside Polymerase Inhibitor)
  • RG7348 (Nucleoside Analogue)
  • R1479 (Polymerase Inhibitor)
  • Mitemcinal Fumarate/GM -611 (Motilin Agonist)
  • Mericitibine/Formerly RG7128/RO5024048 (Cytidine Nucleoside Analog Prodrug)
  
Endocrinology/Metabolism  
Diabetes  
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes  
Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 Receptor Agonists)
Therapeutics that treat non-insulin dependent diabetes by stimulating the Glucagon-Like Peptide (GLP) receptor. GLP regulates gastric emptying, insulin secretion, food intake, and glucagon secretion.

Buyer Products:

  • Taspoglutide
  
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Products that sensitize organs to insulin.

Buyer Products:

  • RG1439/Aleglitazar (Dual PPAR Agonist)
  
Intermediary Metabolism Disorders  
Gout  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat gouty arthritis by preventing cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Hypercholesterolemia  
Cholesteryl Ester Transfer Protein Inhibitors (CETP)
Therapeutics that treat high cholesterol by interrupting with the transfer of lipids between lipoproteins.

Buyer Products:

  • Dalcetrapib/RG1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
  
Parathyroid Gland Disorders  
Hyperparathyroidism (HPT)  
Vitamin D Analogs
Therapeutics that act similar to Vitamin D.

Buyer Products:

  • Rocaltrol (Calcitriol)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • RG4929 (11 Beta HSD Inhibitor)
  • RG7201 (SGLT2 Inhibitor)
  • RG7273 (ABCA1 Inducer)
  • RG7426/Genentech BHT-3021
  • RO5095932
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • RO4998452
  
Pituitary Gland Disorders  
Severe Short Stature  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Genentech - Nutropin/Nutropin AQ (Recombinant Somatropin (Human Growth Hormone))
  
Turner`s Syndrome  
Growth Hormones
Therapeutics similar to pituitary hormones, which stimulate body growth and development.

Buyer Products:

  • Genentech - Nutropin/Nutropin AQ (Recombinant Somatropin (Human Growth Hormone))
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • MAR701 (Peptide Therapy)
  
Hematology  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
  • RG7273 (ABCA1 Inducer)
  
Red Blood Cell (RBC) Disorders  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues by stimulating red blood cell production.

Buyer Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
  • Epogin (Epoetin Beta)
  
Serum Factor Disorders  
Hypercholesterolemia  
Cholesteryl Ester Transfer Protein Inhibitors (CETP)
Therapeutics that treat high cholesterol by interrupting with the transfer of lipids between lipoproteins.

Buyer Products:

  • Dalcetrapib/RG1658 (Cholesteryl Ester Transfer Protein (CETP) Inhibitor)
  
Hypocalcemia  
Vitamin D Analogs
Therapeutics that treat hypocalcemia by increasing serum levels of calcium, as well as helping the bone calcification process.

Buyer Products:

  • Rocaltrol (Calcitriol)
  
White Blood Cell (WBC) Disorders  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics that treat neutropenia by inducing the maturation and proliferation of white blood cells.

Buyer Products:

  • Neutrogin (Granulocyte Colony Stimulating Factor)
  
Immunology  
Autoimmune Disorders  
Anti-Neutrophil Cytoplasmic Antibodies (ANCA) Associated Vasculitis  
Monoclonal Antibodies
Therapeutics that treat Wegener's Granulomatosis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Rituxan (Rituximab)
  
Arthritis  
Rheumatoid Arthritis (RA)  
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Actemra (Tocilizumab)
  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  
Lupus Erythematosus  
Systemic (SLE)  
Immunosuppressants
Therapeutics that treat systemic lupus by inhibiting a full immune response.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
  
Monoclonal Antibodies
Therapeutics that treat systemic lupus by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Buyer Products:

  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  
Multiple Sclerosis (MS)  
Monoclonal Antibodies
Therapeutics that treat multiple sclerosis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  
Immune Deficiency Disorders  
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Buyer Products:

  • Fuzeon (Enfuvirtide)
  
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Invirase (Saquinavir Mesylate)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • RG4934 (Anti-IL-17 Monoclonal Antibody)
  • RG7416 (Anti-LT Alpha Monoclonal Antibody)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • Genentech - Rituxan (Rituximab)
  • R1487 (Kinase Inhibitor)
  • Rontalizumab/RG7415 (Anti-IFN Alpha Monoclonal Antibody)
  • BAL2299 (Nuclear Receptor Modulator)
  • RG7413 (Anti-Beta 7 Monoclonal Antibody)
  • Genentech - MTRX1011A (anti-CD4 Monoclonal Antibody)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  • R1295 (Integrin Antagonist)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • CRACM (Calcium Release-Activated Calcium Modulator) Ion Channel Inhibitor
  • CLIP (Class II Associated Invariant Chain Peptide)
  
Infectious Diseases  
Bacterial  
Antibacterial Agents  
Broad Spectrum  
Antibiotics  
Cephalosporin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Rocephin (Ceftriaxone Sodium)
  • Ceftobiprole Medocaril/BAL5788 (Antibiotic)
  
Narrow Spectrum  
Digestive System  
Shigellosis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat an infection of the intestines caused by Shigella by inhibiting folic acid synthesis.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Otolaryngology (Ear/Nose/Throat)  
Otitis Media  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the middle ear inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Respiratory System  
Bronchitis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the bronchi in the lungs by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Urology  
Urinary Tract Infections (UTI)  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections of the urinary tract by inhibiting dihydrofolate reductase resulting in decreased bacterial nucleic acid/protein production.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Mycological (Fungal)  
Antifungal Agents  
Broad Spectrum  
Azoles  
Triazoles
Therapeutics that treat fungal infections by increasing permeability of the cell wall and causing a toxic build up of hydrogen peroxide.

Buyer Products:

  • Isavuconazole/BAL8557 (Antifungal Agent)
  
Narrow Spectrum  
Respiratory System  
Pneumocystis Carinii Pneumonia (PCP)  
Dihydrofolate Reductase Inhibitors/Dihydropteroate Synthetase Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by interfering with folic acid synthesis and growth of organism.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Buyer Products:

  • Serine Palmitoyl Transferase Inhibitor
  • CS-023 (Parenteral Carbapenem)
  • RG7227 (Danoprevir)/Formerly ITMN-191
  • Ceftobiprole Medocaril/BAL5788 (Antibiotic)
  • Isavuconazole/BAL8557 (Antifungal Agent)
  • R1270 (Levovirin)
  • Mericitibine/Formerly RG7128/RO5024048 (Cytidine Nucleoside Analog Prodrug)
  • RG7432 (Nucleoside Polymerase Inhibitor)
  • RG7348 (Nucleoside Analogue)
  • R1461 (Fusion Protein)
  • R1479 (Polymerase Inhibitor)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in very early stages of research where no human subject is involved.

Buyer Products:

  • Tamiflu (Oseltamivir)
  • BAL8349 (Antifungal Agent)
  
Viral  
DNA Viruses  
Hepadnavirus  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months with natural proteins that have antiviral activity.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  
Herpesvirus  
Cytomegalovirus (CMV)  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  
RNA Viruses  
Flavivirus  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections characterized by long term inflammation of the liver by enhancing the immune system and by inhibiting replication of viral DNA.

Buyer Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
  
Orthomyxovirus  
Influenza A  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza A virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Tamiflu (Oseltamivir)
  
Influenza B  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza B virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Tamiflu (Oseltamivir)
  
Retrovirus  
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Buyer Products:

  • Fuzeon (Enfuvirtide)
  
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Invirase (Saquinavir Mesylate)
  
Musculoskeletal System  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
  • RG7416 (Anti-LT Alpha Monoclonal Antibody)
  • RG4934 (Anti-IL-17 Monoclonal Antibody)
  • R1487 (Kinase Inhibitor)
  • Genentech - MTRX1011A (anti-CD4 Monoclonal Antibody)
  • R1295 (Integrin Antagonist)
  
Skeletal Disorders  
Bone Disorders  
Osteoporosis  
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts.

Buyer Products:

  • Boniva (Ibandronate Biphosphonate)
  
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts while not stimulating the endometrial lining of the uterus.

Buyer Products:

  • Evista (Raloxifene Hydrochloride)
  
Joint Disorders  
Ankylosing Spondylitis  
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat ankylosing spondylitis interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Actemra (Tocilizumab)
  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by inhibiting cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Osteoarthritis (OA)  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Rheumatoid Arthritis (RA)  
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Actemra (Tocilizumab)
  • Genentech - Rituxan (Rituximab)
  • Genentech - Ocrelizumab/RG1594 (Humanized Anti-CD20 Monoclonal Antibody)
  
Neurology  
Neurological Disorders  
Epilepsy  
Primary Generalized Seizures  
Absence (Petit Mal)  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Akinetic Pattern  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Myoclonic  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevent nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
  
Neuromuscular Disorders  
Multiple Sclerosis (MS)  
Monoclonal Antibodies
Therapeutics that treat multiple sclerosis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Genentech - Rituxan (Rituximab)
  
Parkinson`s Disease (PD)  
Adjunctive Treatments  
Dopamine Receptor Agonists
Therapeutics that assist in the treatment of the disorder involving nerve cell loss in portions of the brain that leads to uncontrolled tremors, abnormal posture and speech problems by stimulating dopamine receptors on neurons.

Buyer Products:

  • Madopar DR (Levodopa)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • RG1578 (mGluR2 Antagonist)
  • RG1662 (GABA-A Alpha5 Inverse Agonist)
  • RG7090 (mGluR5 Antagonist)
  • RG7166 (Triple Reuptake Inhibitor)
  • R4996/MEM 63908 (Nicotinic Alpha-7 Receptor Agonist)
  • RG3487/MEM 3454 (Nicotinic Alpha-7 Receptor Partial Agonist)
  • Genentech - Rituxan (Rituximab)
  • MT 500 (GPCR Modulator)
  • RG1450/Gantenerumab (Amyloid Beta Peptide Antibody)
  • EVT 103 (NMDA Receptor Antagonist)
  • EVT 101 (NMDA Receptor Antagonist)
  • RG7412 (Anti-A Beta Monoclonal Antibody)
  
Psychiatric Disorders  
Anxiety  
Generalized Anxiety Disorder (GAD)  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Valium (Diazepam)
  
Panic Disorder  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Klonopin (Clonazepam)
  
Schizophrenia  
Glycine Reuptake Inhibitors
Therapeutics that treat schizophrenia by inhibiting the reuptake of glycine by neurotransmitters.

Buyer Products:

  • RG1678
  
Oncology
Breast Cancer  
Localized  
Monoclonal Antibodies
Therapeutics that treat breast cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Genentech - Herceptin (Trastuzumab)/Avastin (Bevacizumab)
  • Herceptin (Trastuzumab)
  
Metastatic  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage breast cancers that have spread beyond their original tumor site by inhibiting the production of DNA.

Buyer Products:

  • Xeloda (Capecitabine)
  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of breast cancer cells and inhibit the cancer cells' growth and induce their death.

Buyer Products:

  • Herceptin (Trastuzumab)
  • Genentech - Omnitarg (Pertuzumab)
  • Trastuzumab Emtansine (T-DM1)
  • Avastin (Bevacizumab)
  
Dermatology  
Basal Cell Carcinoma  
Hedgehog Pathway Inhibitors
Therapeutics that treat and manage cancers arising from the epidermal basal cells by inhibiting signaling in the Hedgehog pathway, which functions to regulate cell growth.

Buyer Products:

  • Erivedge (Vismodegib)
  
Kaposi`s Sarcoma  
Interferons
Therapeutics that treat and manage cancers of spindle cells by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Malignant Melanoma  
Raf Kinase Inhibitors
Therapeutics that treat skin cancer by interrupting the signaling pathways that are responsible for tumor cell proliferation.

Buyer Products:

  • Genentech - Zelboraf (Vemurafenib)/Formerly RG7204/PLX4032 (BRAF Kinase Inhibitor)
  
Digestive System  
Colon Cancer/Colorectal Cancer  
Metastatic  
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage colorectal tumors that have spread beyond their original tumor site by inhibiting the production of DNA.

Buyer Products:

  • Xeloda (Capecitabine)
  
Monoclonal Antibodies
Therapeutics that treat colorectal cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
  
Gastric Cancer (Stomach Cancer)  
Metastatic  
Monoclonal Antibodies
Therapeutics that treat gastric cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Herceptin (Trastuzumab)
  
Hepatic Cancer (Liver Cancer)  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage hepatic (liver) cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Buyer Products:

  • Genetech - Tarceva (Erlotinib)
  
Pancreatic Cancer  
Metastatic  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Buyer Products:

  • Genetech - Tarceva (Erlotinib)
  
Hematology  
Leukemia (White Blood Cell Cancer)  
Lymphoid  
Chronic  
Hairy Cell  
Interferons
A recombinantly produced protein normally produced by the body to fight viral infection used to treat and manage a slowly progressing cancer of lymphoid cells characterized by numerous irregular cytoplasmic projections.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Lymphocytic (CLL)  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of leukemia cells and thereby induce their death.

Buyer Products:

  • Genentech - Rituxan (Rituximab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
  
Myeloid  
Chronic  
Myelogenous (CML)  
Interferons
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
  
Lymphoma (Lymphatic Cancer)  
Non-Hodgkin`s Lymphoma (NHL)  
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of lymphoma cells and thereby induce their death.

Buyer Products:

  • Rituxan (Rituximab)/Avastin (Bevacizumab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
  • Genentech - Rituxan (Rituximab)
  
Neurology  
Brain Cancer  
Glioma  
Glioblastoma  
Monoclonal Antibodies
Therapeutics that treat and manage tumors of the glial cells by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
  • Bevacizumab/Temozolomide/Vorinostat Combination Therapy
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • RG7597 (Anti-HER3/EGFR Monoclonal Antibody)
  • RG1507 (IGF-1R Antagonist)
  • MKC-1/R440 (Cell Cycle Inhibitor)
  • CAL (Anti-PTHrP Monoclonal Antibody)
  • CHC 12103 (Polyglutamate TXL)
  • Therafab
  • R1549/Formerly Pemtumomab
  • Diflomotecan (Topoisomerase Inhibitor I)
  • E2F Activating Compound
  • ARQ 501/R1668 (E2F Modulator)
  • Trastuzumab Emtansine (T-DM1)
  • PRO64553 (Anti-CD40 Antibody)
  • Avastin (Bevacizumab)
  • RG7159/GA101 (Humanized Anti-CD20 Monoclonal Antibody)
  • R547 (Enzyme Inhibitor)
  • Vadimezan/AS1404
  • Genetech - Tarceva (Erlotinib)
  • Yervoy (Ipilimumab)/Vemurafenib (BRAF Kinase Inhibitor)
  • Erivedge (Vismodegib)
  • RG7420/XL518 (MEK Inhibitor)
  • RG7459 (IAP Antagonist)
  • Genentech - Omnitarg (Pertuzumab)
  • RG7321/GDC-0941 (P13 Kinase Inhibitor)
  • Genentech - Erlotinib/Pertuzumab Combination Therapy
  • Genentech - ABT-869 (VEGFR Kinase Inhibitor)
  • Genentech - Avastin/Sutent Combination Therapy (Bevacizumab/Sunitinib)
  • Genentech - Dulanermin (rhApo2L/TRAIL)
  • Genentech - Apomab (Proapoptotic Receptor Agonist)
  • Navitoclax/RG7433/Genentech ABT-263 (Bcl-2 Antagonist)
  • Genentech - Avastin (Bevacizumab)/Tarceva (Erlotinib HCl)
  • Genentech - MetMAb
  • Genentech - Zelboraf (Vemurafenib)/Formerly RG7204/PLX4032 (BRAF Kinase Inhibitor)
  • RG7594 (Monoclonal Antibody)
  • RG7593 (Anti-CD22 Monoclonal Antibody)
  • RG7440 (AKT Inhibitor)
  • RG7422 (PI3 Kinase Inhibitor)
  • RG7421 (MEK (Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase) Inhibitor)
  • RG7414 (Anti-EGFL7(Epidermal Growth Factor Like Domain Multiple 7))
  • RG7347 (Anti-NRP1)
  • RG7334 (Anti-PLGF)
  • RG7304 (Raf/MEK Dual Inhibitor)
  • RG7256 (BRAF Kinase Inhibitor)
  • RG7167 (CIF/MEK Inhibitor)
  • RG7160 (EGFR Monoclonal Antibody)
  • RG7112 (MDM2 Antagonist)
  • RG3484 (HPV16 Vaccine)
  • Anti-Glypican Monoclonal Antibody
  • Topoisomerase I Inhibitor
  • RG7444 (Anti-FGFR3 Monoclonal Antibody)

Target Products:

  • DN24-02 (Immunotherapy)
  • D-3263 (Trp-p8 Small Molecule)
  • Provenge (Sipuleucel-T)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Buyer Products:

  • Elomotecan/BN80927 (Topoisomerase I/II Inhibitor)

Target Products:

  • Carcinoembryonic Antigen (CEA) Vaccine
  • TRPM8 (Trp-p8 Small Molecule)
  • CA-9 (Carbonic Anhydrase 9 Antigen)
Respiratory System/Thoracic  
Lung Cancer  
Non Small Cell Lung Cancer (NSCLC)  
EGFR-TK Inhibitors/Monoclonal Antibodies
Therapeutics that treat lung cancer by blocking the tyrosine kinase enzyme and by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Genentech - Avastin (Bevacizumab)/Tarceva (Erlotinib HCl)
  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the tyrosine kinase enzyme by switching off the signals from the epidermal growth factor receptors.

Buyer Products:

  • Genetech - Tarceva (Erlotinib)
  
Monoclonal Antibodies
Therapeutics that treat lung cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
  • Genentech - MetMAb
  
Urology
Kidney Cancer (Renal Cell Carcinoma)  
Metastatic  
Monoclonal Antibodies
Therapeutics that treat kidney cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
  
Ovarian Cancer  
Adenocarcinoma  
Monoclonal Antibodies
Therapeutics that treat ovarian cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • R1549/Formerly Pemtumomab
  
Metastatic  
Monoclonal Antibodies
Therapeutics that treat and manage ovarian cancers that have spread beyond their original tumor site by binding to specific structures on the surface of the tumor, eliciting a reaction which results in tumor cell death.

Buyer Products:

  • Avastin (Bevacizumab)
  
Prostate Cancer  
Metastatic  
Vaccines
Therapeutics that treat prostate cancers that have spread beyond the initial tumor by eliciting a specific immune response.

Target Products:

  • Provenge (Sipuleucel-T)
  
Ophthalmology  
Degenerative Disorders  
Edema  
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular edema by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Buyer Products:

  • Lucentis (Ranibizumab)
  
Macular Degeneration (AMD)  
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular degeneration by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Buyer Products:

  • Lucentis (Ranibizumab)
  
Retinitis  
AIDS-Related Cytomegalovirus (CMV) Retinitis  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of eye disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Lucentis (Ranibizumab)
  • RG7417 (Anti-Factor D Monoclonal Antibody)
  
Pain Management  
Anesthesia  
General (Systemic)  
Reversal  
Gamma-Aminobutyric Acid (GABA) Receptor Antagonists
Therapeutics that reverse general anesthesia by competitively inhibiting benzodiapizines at the GABA receptors, thus reducing their effect and reversing the anesthesia.

Buyer Products:

  • Romazicon (Flumazenil)
  
Non-Narcotics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  • Aleve (Naproxen Sodium)
  
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Decongestants
Therapeutic combinations that produce insensibility or numbness through the inhibition of prostoglandins while also preventing nasal decongestion.

Buyer Products:

  • Aleve Cold & Sinus (Naproxen/Pseudoephedrine)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of pain in early stages of clinical research where human subject is involved.

Buyer Products:

  • Bondronat (Ibandronate)
  • EVT 101 (NMDA Receptor Antagonist)
  
Respiratory System  
Lower Respiratory Tract Disorders (Lung Disorders)  
Asthma  
Prophylactic Treatments  
Monoclonal Antibodies
Therapeutics that treat asthma with monoclonal antibodies.

Buyer Products:

  • Xolair (Omalizumab)
  
Cystic Fibrosis (CF)  
Recombinant Human Deoxyribonuclease I
Therapeutics that relieve symptoms of cystic fibrosis by hydrolyzing the DNA in the sputum of cystic fibrosis patients thus reducing viscosity of the secretions and aiding lung function.

Buyer Products:

  • Genentech - Pulmozyme (Dornase Alfa)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Ro 27-2411 (Integrin Antagonist)
  • RG667/Palovarotene (Nuclear Receptor)
  • RG7449 (Anti-M1 Prime Monoclonal Antibody)
  • RG7185 (CRTH2 Antagonist)
  • R1295 (Integrin Antagonist)
  • Lebrikizumab/RG3637 (Humanized Anti-IL13 Antibody)
  • RG4930 (Anti-OX40L Monoclonal Antibody)
  
Surgery  
Cardiovascular System  
Complications  
Peripheral Arterial Occlusion  
Thrombolytic Agents
Therapeutics that treat diseases of the blood vessels outside the heart by dissolving blood clots.

Buyer Products:

  • Cathflo Activase (Alteplase)
  
Toxicology  
Substance Abuse  
Withdrawal  
Alcohol  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Buyer Products:

  • Valium (Diazepam)
  
Transplantation  
Bone Marrow  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Cytovene (Ganciclovir)
  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte (rhG-CSF)
Therapeutics containing biological proteins that stimulate the formation of certain white blood cells called granulocytes.

Buyer Products:

  • Neutrogin (Granulocyte Colony Stimulating Factor)
  
Heart  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that help manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
  
Hepatic (Liver)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
  
Lung  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Pancreas  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the management of rejection and infection in early stages of clinical research where human subject is involved.

Buyer Products:

  • BCX-4208 (Second-Generation PNP Inhibitor)
  
Renal (Kidney)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
  
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
  
Monoclonal Antibodies
Protein-based therapeutics that target specific substances like proteins.

Buyer Products:

  • Zenapax (Daclizumab)
  
Urology
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • PLX5568 (Raf Kinase Inhibitor)
  • R1484 (GPCR Modulator)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1437 (GPCR Antagonist)

Target Products:

  • TRPM8 (Trp-p8 Small Molecule)
Urological Disorders  
Kidney (Renal)  
Chronic Renal Failure (CRF)  
Complications  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat the condition resulting from the scarcity of red blood cells by inducing the production of red blood cells.

Buyer Products:

  • Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
  
Edema  
Loop Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine.

Buyer Products:

  • Demadex (Toresmide)
  
Weight Management  
Obesity  
Lipase Inhibitors
Therapeutics that reduce the absorption of fat by inhibiting production of lipase, which is an enzyme that helps breaking down fat in the food.

Buyer Products:

  • Xenical (Orlistat)
  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • MAR701 (Peptide Therapy)
  
Wound Management  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of wounds in very early stages of research where no human subject is involved.

Buyer Products:

  • Vascular Endothelial Growth Factor
  
Healthcare Services  
Patient Care  
Ambulatory/Outpatient  
Diagnostic  
Clinical Laboratories  
Pathology
Similar to routine clinical lab services, pathology services are provided by licensed medical physicians and therefore may involve the additional role of diagnosis and consultation of results with the referring physician.

Buyer Products:

  • Quantitative Diagnostics Laboratories, Inc. (QDL)
  
Specialized
Specialized laboratory testing services involving highly specialized equipment, personnel, and procedures.

Buyer Products:

  • Verum Diagnostica GmbH
  
Medical Devices  
Clinical Diagnostics  
Chemistry  
Analyzers  
Clinical Chemistry
Analyzers used to quantify various chemicals in blood plasma or serum samples. Blood gas and protein analyzers are included.

Buyer Products:

  • Roche Diagnostics - Roche/Hitachi 902/912
  • Roche Diagnostics - Cobas 8000 Modular Analyser Series
  • Roche Diagnostics - Cobas Integra Series
  • Roche Diagnostics - AVL Compact 1-3
  • Roche Diagnostics - AVL 9180 Series
  • Roche Diagnostics - AVL 988 Series
  • Roche Diagnostics - OMNI Series
  • Roche Diagnostics - Reflotron Series
  
Urinalysis
Analyzers used to perform chemical, physical and microscopic analysis of urine.

Buyer Products:

  • Roche Diagnostics - Miditron M
  • Roche Diagnostics - Urisys 2400
  • Roche Diagnostics - Urisys 1100
  • Roche Diagnostics - Miditron Junior II
  
Home Testing  
Glucose Testing/Diabetes Monitoring  
Invasive  
Continuous Analysis
Glucose test devices which measure patient glucose levels on a continual basis.

Buyer Products:

  • Roche Diagnostics - GlucOnline Microdialysis System
  
Random Analysis
Glucose test devices which measure patient glucose levels on a random basis.

Buyer Products:

  • Roche Diagnostics - Accu-Chek Complete/Sensor Complete Meter
  • Roche Diagnostics - Accu-Chek Advantage/Advantage II/Sensor Meter
  • Roche Diagnostics - Accu-Chek Active Meter
  • Roche Diagnostics - Accu-Chek Aviva
  • Roche Diagnostics - Accu-Check Nano SmartView
  • Roche Diagnostics - Accu-Chek Voicemate
  • Roche Diagnostics - Accu-Chek Mobile
  • Roche Diagnostics - Accu-Chek Combo
  • Roche Diagnostics - Accu-Chek Simplicity
  • Roche Diagnostics - Accu-Chek Inform System
  • Roche Diagnostics - AccuData GTS/AccuData HDM
  • Roche Diagnostics - Accu-Chek Compact Meter
  
Test Strips
Specific glucose test devices used with glucose monitors.

Buyer Products:

  • Roche Diagnostics - Glucotrend Strips
  • Roche Diagnostics - Accu-Chek Compact Test Drums
  • Roche Diagnostics - Accu-Chek Comfort Curve/Sensor Comfort/Advantage Comfort/Advantage II Test Strips
  • Roche Diagnostics - Accu-Chek Active Test Strips
  • Roche Diagnostics - Accu-Chek Advantage Test Strips
  
Point of Care Testing  
Critical Care Analysis  
Analyzers
Chemistry analyzers which may be used for the chemical analysis of body fluids and designed for use at the bedside during the course of patient care.

Buyer Products:

  • Roche Diagnostics - BioVeris Elecsys System
  • Roche Diagnostics - Accutrend System
  
Test Cartridges
Specific analyte test devices used in conjunction with critical care chemistry analyzers.

Buyer Products:

  • Roche Diagnostics - BioVeris Elecsys System
  
Kits  
Cardiac
Test kits used to aid in the diagnosis of heart conditions.

Buyer Products:

  • Roche Diagnostics - Cobas h 232 System
  • Roche Diagnostics - Cardiac D-Dimer
  
Reagents  
Calibrators
Specific standards of known concentration for analytes that are used to define test performance of chemistry analyzers, including blood gas analyzers and other routine analyte analyzers.

Buyer Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
  
Controls
Materials with known concentrations used to verify the accuracy of test systems, including blood gas system, routine system, microbiology system, and other specialized systems.

Buyer Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
  
Test Kits  
Genetic/Molecular Diagnostics  
Disease Diagnosis  
Infectious Diseases  
Automated Analyzers
Analyzers designed for genetic probe assays to detect and quantitate microorganisms.

Buyer Products:

  • Roche Diagnostics - COBAS AmpliPrep System
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
  • Roche Diagnostics - COBAS AMPLICOR Analyser
  
Reagents  
Bacterial  
Tuberculosis
Genetic probe for detection and/or quantitation of Mycobacterium tuberculosis.

Buyer Products:

  • Roche Diagnostics - COBAS AMPLICOR MTB Test/AMPLICOR MTB Test
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium Intracellular (MIN) Test/AMPLICOR MIN Test
  • Roche Diagnostics - COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
  
Viral  
Cytomegalovirus
Genetic probe for detection and/or quantitation of Cytomegalovirus.

Buyer Products:

  • Roche Diagnostics - AMPLICOR CMV Test
  • Roche Diagnostics - COBAS AMPLICOR CMV Monitor Test
  • Roche Diagnostics - BioVeris NucliSens/NASBA QR
  
Hepatitis B Virus
Genetic probes for detection and/or quantitation of HBV.

Buyer Products:

  • Roche Diagnostics - COBAS AmpliScreen HBV Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
  • Roche Diagnostics - COBAS TaqMan HBV Test
  
Hepatitis C Virus
Genetic probes for detection and/or quantitation of HCV.

Buyer Products:

  • Roche Diagnostics - COBAS AMPLICOR HCV Test/AMPLICOR HCV Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
  • Roche Diagnostics - COBAS AmpliScreen HCV Test
  • Roche Diagnostics - COBAS TaqMan HCV Test
  • Roche Diagnostics - PCR COBAS TaqMan HCV Test
  • Roche Diagnostics - COBAS AMPLICOR HCV Monitor Test/AMPLICOR HCV Monitor Test
  
Human Immunodeficiency Virus (HIV)
Genetic probes for detection and quantification of HIV.

Buyer Products:

  • Roche Diagnostics - AmpliPrep/COBAS TaqMan HIV-1 Test
  • Roche Diagnostics - COBAS AmpliScreen HIV-1 Test
  • Roche Diagnostics - Cobas TaqScreen MPX Test
  
Human Papilloma Virus
Genetic probes for the detection of HPV.

Buyer Products:

  • Roche Diagnostics - Cobas HPV Test
  • Roche Diagnostics - Digene Hybrid Capture II HPV Test
  • Roche Diagnostics - Linear Array HPV Genotyping Test
  • Roche Diagnostics - Amplicor HPV Test
  
Influenza (Flu)
Genetic probes for detection and/or quantitation of Influenza (Flu) virus.

Buyer Products:

  • Roche Diagnostics - Influenza A/H1N1 Detection Set
  
West Nile Virus
Genetic probes for detection and/or quantitation of West Nile Virus.

Buyer Products:

  • Roche Diagnostics - TaqScreen West Nile Virus Test
  
Oncology  
Colorectal Cancer/Colon Cancer
Tests designed to diagnose colorectal cancer/colon cancer through genetic detection and analysis.

Buyer Products:

  • Roche Diagnostics - hemo FEC
  
Pharmacogenetic
Tests designed to determine patients' reactions to specific medications based on their genes.

Buyer Products:

  • Roche Diagnostics - AmpliChip CYP450 Test
  • Roche Diagnostics - Ventana Medical Systems INFORM HER2 SISH DNA Probe Assay
  
Urinalysis
Test kits used to perform chemical and physical analysis of urine.

Buyer Products:

  • Roche Diagnostics - Chemstrip Series
  
Hematology/Hemostasis  
Hematology  
Analyzers  
Multiple Parameter
Hematology analyzers designed for use in determining multiple hematological parameters in a clinical setting.

Buyer Products:

  • Roche Diagnostics - Cobas b121 System
  • Roche Diagnostics - Cobas b 221 System
  
Hemostasis  
Analyzers  
Automated
Automated coagulation analyzers.

Buyer Products:

  • Roche Diagnostics - Stago Systems
  • Roche Diagnostics - Coasys Plus C
  
Reagents  
Test Kits  
Thrombin/Thromboplastin
Test kits used to perform thrombin time, prothrombin time, and activated partial thromboplastin time assays.

Buyer Products:

  • Roche Diagnostics - CoaguChek Series
  
Histology  
Imaging Systems  
Cytopathology
Systems designed to enhance microscopic visualization of human cells through camera, video or digital viewing processes.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso System for HER2 (4B5)
  • Roche Diagnostics - Ventana Companion Algorithm p53 (DO-7) Image Analysis Application
  • Roche Diagnostics - Ventana Companion Algorithm Progesterone Receptor (PR) (1E2) Image Analysis Application
  • Roche Diagnostics - Ventana Image Analysis System (VIAS)
  
Processing Equipment  
Slide Processing
Slide processing equipment including slide labelers, slide makers, and immunohistochemistry and in-situi hybridization slide stainers.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems EBAR SLS Slide Labeling System
  • Roche Diagnostics - Ventana Medical Systems Discovery XT System
  • Roche Diagnostics - Ventana Medical Systems BenchMark LT/ XT System
  • Roche Diagnostics - Ventana Medical Systems Automated Staining Systems
  • Roche Diagnostics - Ventana Medical Systems BenchMark ULTRA System With Ultimate Reagent Access (URA)
  • Roche Diagnostics - Ventana Medical Systems iScan Coreo Au
  
Tissue Processing
Instrument used for the automated processing and embedding of tissue samples.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Tissue Processor
  
Reagents  
Biomolecular Stains
Vital reagents used in the staining of tissue in order to view microscopically for pathology.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems PATHWAY c-KIT
  • Roche Diagnostics - Ventana Medical Systems Immunohistochemistry (IHC) Detection Systems And Ancillary Products
  
Kits  
DNA Probes
Staining kits which utilize DNA probes to mark specific cells for staining.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Inform ISH/FISH Probes
  
In-Situ Hybridization (ISH)
Staining kits which utilize In-Situ hybridization techniques to mark specific cells for staining.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  
Preparation/Preservation
Reagents used for preservation of tissues and preparation of tissues for analysis.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Immunohistochemistry (IHC) Detection Systems And Ancillary Products
  
Immunoassays  
Analyzers  
Accessories
Reagents and equipment used to facilitate immunoassay testing.

Buyer Products:

  • Roche Diagnostics - Elecsys Anti-HBc IgM Assay
  
Multiple Assay
Immunoassay analyzer designed to perform multiple assays over multiple modalities.

Buyer Products:

  • Roche Diagnostics - Cobas 8000 Modular Analyser Series
  • Roche Diagnostics - BioVeris Elecsys System
  • Roche Diagnostics - BioVeris E170
  • Roche Diagnostics - BioVeris Picolumi
  • Roche Diagnostics - Cobas Core II
  
Reagents  
Calibrators
Specific standards of known concentration for analytes that are used to define and or measure test performance of immunoassay test kits and systems.

Buyer Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
  
Controls
Reagents used to verify the function and reliability of immunoassay test kits and systems.

Buyer Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
  
Test Kits  
Cardiovascular System  
Cardiac
Immunoassay kits used to screen, diagnose or monitor cardiac conditions.

Buyer Products:

  • Roche Diagnostics - TROPT Sensitive
  • NT-proBNP
  • Roche Diagnostics - Cardiac Reader
  
Infectious Diseases  
Bacterial
Immunoassay kits which test for the presence of infectious diseases or previous infection caused by bacteria.

Buyer Products:

  • Ventana Anti-Helicobacter Pylori (SP48) Rabbit Monoclonal Primary Antibody
  • Roche Diagnostics - Amplicor M. tuberculosis Test
  • Roche Diagnostics - COBAS AMPLICOR CT/NG Test/AMPLICOR CT/NG Test
  • Cobas 4800 CT/NG Test
  
Viral
Immunoassay kits which test for the presence of infectious disease or previous infection caused by viruses.

Buyer Products:

  • IgM Antibody To Hepatitis B Core Antigen (Anti-HBc IgM)
  • Roche Molecular Systems - Cobas HPV Test
  • Roche Diagnostics - AMPLICOR HIV-1 Monitor Test
  • Roche Diagnostics - COBAS Amplicor HIV-1 Test
  
Oncology  
Breast Cancer
Diagnostic assay used to detect specific breast tumor or cancer markers.

Buyer Products:

  • BCM 18 (Breast Cancer Marker)
  • Roche Diagnostics - Ventana Medical Systems PATHWAY HER-2/neu (4B5) Rabbit Monoclonal Antibody
  
Cervical Cancer
Diagnostic assay used to detect specific cervical tumor or cancer markers.

Buyer Products:

  • mtm Laboratories AG - CINtec Histology Kit
  
Digestive System Cancer
Diagnostic assay used to detect specific digestive system cancer markers.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems VentanaDx c-KIT
  
Multiple Tumor
Diagnostic assay used to detect markers associated with multiple cancer types.

Buyer Products:

  • Roche Molecular Diagnostics - Cobas 4800 BRAF V600 Mutation Test
  • Roche Diagnostics - Cobas Core Reagent Series
  
Opthalmology
Immunoassay kits used to quantify markers associated with opthalmic diseases.

Buyer Products:

  • Roche Diagnostics - OnTrak TesTcard 9
  • Roche Diagnostics - Cobas Integra Reagents Series
  
Toxicology/Drugs Of Abuse  
Drugs Of Abuse
Immunoassay test kits which test for drugs of abuse in body fluids.

Buyer Products:

  • Roche Diagnostics - OnTrak TesTcard 9
  • Roche Diagnostics - Cobas Integra Reagents Series
  
Therapeutic Drugs
Immunoassay test kits which measure levels of therapeutic drugs in body fluids.

Buyer Products:

  • Roche Diagnostics - Cobas Integra Reagents Series
  
Specimen Collection  
Blood  
Capillary  
Lancets
Sharps type of device used to puncture the skin in order to collect a capillary blood sample.

Buyer Products:

  • Roche Diagnostics - Accu-Chek Lancing Devices
  
Drug Delivery  
Infusion Therapy  
Delivery Systems  
Insulin  
Pumps  
External/Random Analysis Monitoring System
External pump that delivers insulin to the patient and measure patient glucose levels as a blood sample is obtained.

Buyer Products:

  • Roche Diagnostics - Accu-Chek Combo
  
Implanted
Implanted pump that delivers insulin to the patient.

Buyer Products:

  • Roche Diagnostics - Solo Insulin Dispensing Patch
  
Outsourced Biomedical Services  
Analytical Services
The Analytical Services Subsector includes outsourced services that utilize analytical instruments to analyze biological and chemical samples.

Buyer Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
  
Bioanalytical Services  
Nucleic Acid Sequencing
Bioanalytical services that identify the location of each nucleotide in a nucleic acid sample.

Buyer Products:

  • Roche Diagnostics - 454 Life Sciences Sequencing Services
  
Nucleic Acid Synthesis
Bioanalytical services that produce nucleic acids from individual nucleotides.

Buyer Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
  
Drug Discovery Services  
Lead Discovery/Validation/Optimization  
Assay Development
Bioanalytical services that are used to develop biologically based tests for use in high throughput screening (HTS).

Buyer Products:

  • Roche Diagnostics - BioVeris Contract Services Organization
  
High Throughput Screening (HTS)
Bioanalytical services that allow for the biological testing of up to 10,000 compounds each day.

Buyer Products:

  • Roche Diagnostics - BioVeris Sector Line
  • Roche Diagnostics - BioVeris Contract Services Organization
  
Lead Biologics  
Antibodies
Biological lead compounds which have a specific amino acid sequence that only interacts with specific substances to cause an immunological response.

Buyer Products:

  • ARIUS FunctionFIRST Technology
  
Target Discovery/Validation  
Databases  
Genomics  
Human
Genomic databases that contain human genetic information.

Buyer Products:

  • Roche NimbleGen - SeqCap EZ Library
  
Services
Drug discovery services that discover and validate drug targets for the development of novel biopharmaceutical drugs.

Buyer Products:

  • Roche Diagnostics - BioVeris Sector Line
  
Scientific Products  
Analytical Instruments  
Automation/Processing Equipment  
Automation Equipment  
Robotic Instruments  
Workstations
Robotic instrument systems that transfer liquid and gas samples and also heat and cool samples.

Buyer Products:

  • Roche Diagnostics - Task Targeted Automation
  
Bioanalytical Instruments  
Bioanalytical Consumables  
Cell Biology  
Cell Culture  
Cell Lines
Cell biology consumables that is a permanently established cell culture which proliferates indefinitely given appropriate fresh medium and space.

Buyer Products:

  • Roche Diagnostics - BioVeris Giant Cell Tumor Conditioned Medium (GCT-CM)
  
Hybridomas
Cell culture reagents that are used to support Hybridomas for antibody production.

Buyer Products:

  • Roche Diagnostics - BioVeris Hybridoma Cloning Factor (HCF)
  
Media
Cell biology consumables used for the growth of cells or organs.

Buyer Products:

  • Roche Diagnostics - BioVeris Hybridoma Cloning Factor (HCF)
  
Reagents  
Lymphokines/Cytokines
Cell culture reagents that are used during cellular assays.

Buyer Products:

  • Roche Diagnostics - BioVeris Immunoassay Reagents
  
Stains/Dyes
Cell culture reagents used for the coloration of samples.

Buyer Products:

  • Roche Diagnostics - BioVeris BV-TAG
  
Immunology  
Kits  
Enzyme-Linked Immunoabsorbent Assay (ELISA)
Kits used for the generalized analysis of serum samples for the detection of antibodies to infectious diseases.

Buyer Products:

  • Roche Diagnostics - BioVeris Immunoassay Reagents
  
Reagents  
Proteins  
Antibodies
Immunology proteins that are used for the detection of specific substances, including conjugated, unconjugated, monoclonal and polyclonal antibodies.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  
Cytokines
Immunology reagents that are used as intracellular mediators.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  
Enzymes
Immunology reagents that are produced by a living organism to catalyze a chemical reaction.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  
Molecular Biology  
Electrochemiluminescence (ECL)  
Reagents
Chemicals used in the preparation and analysis of samples.

Buyer Products:

  • Roche Diagnostics - BioVeris Protein-Protein, Receptor-Ligand And Nucleic Acid-Protein Binding Assays
  • Roche Diagnostics - BioVeris Nucleic Acid Detecion Assays
  • Roche Diagnostics - BioVerify Test Kit
  
Nucleic Acid Analysis  
Automated Nucleic Acid Purification Systems
Fully automated systems for purification of DNA/RNA from blood samples.

Buyer Products:

  • Roche Diagnostics - Cobas s 201 System
  
Kits  
Nucleic Acid  
Sequencing
Nucleic acid analysis kits that are used for the sequencing of genetic samples.

Buyer Products:

  • Roche Diagnostics - 454 Life Sciences Genetic Variation/Sequencing Kits
  
Transfection
Nucleic acid analysis kits that are used for the introduction of DNA into a recipient eukaryote cell and its subsequent integration into the recipient cells chromosomal DNA

Buyer Products:

  • Roche Diagnostics - FuGENE
  
Polymerase Chain Reaction (PCR)  
Amplification
Polymerase chain reaction (PCR) consumables used for the amplification of genetic samples.

Buyer Products:

  • Roche Diagnostics - COBAS AmpliPrep/COBAS TaqMan System
  
Detection
Polymerase chain reaction (PCR) consumables used for the detection of genetic samples.

Buyer Products:

  • Roche Custom Biotech MycoTOOL PCR-Test
  • Roche Diagnostics - FastStart High Fidelity PCR System
  • Roche Diagnostics - COBAS AmpliPrep/COBAS TaqMan System
  
Purification
Polymerase chain reaction (PCR) consumables used for the purification of genetic samples.

Buyer Products:

  • Roche Diagnostics - FastStart High Fidelity PCR System
  
Reagents  
Nucleic Acids
Nucleic acid analysis reagents that are made of nucleotides.

Buyer Products:

  • Roche Diagnostics - Spring BioScience FastClone PCR-Ready cDNAs
  • Roche Diagnostics - BioVeris Nucleic Acid Detecion Assays
  
Protein Analysis  
Kits  
Detection
Protein analysis kits used for the detection of amino acids.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
  • Roche Diagnostics - BioVeris Protein-Protein, Receptor-Ligand And Nucleic Acid-Protein Binding Assays
  
Expression
Kits used to perform protein expression analysis.

Buyer Products:

  • Roche Diagnostics - Spring BioScience In-Situ Hybridization (ISH) Antibodies/Kits
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
  
Biomolecular  
Microarray Technology  
Consumables
Molecular biology consumables used for microarray and biochip instrumentation. Includes kits, chips, and reagents.

Buyer Products:

  • Roche Diagnostics - Nimblegen Sequence Capture Arrays
  • Roche Diagnostics - Ventana Medical Systems Antibody Microarrays
  • Roche Diagnostics - AmpliChip CYP 450
  
Microplate Readers  
Accessories
Supplementary products used to enhance the performance of a microplate reader, including detectors, incubators, dispensers, plate handlers, validation plates, and washers. Also includes consumable microplate reader kits.

Buyer Products:

  • Roche Diagnostics - BioVeris M-Series Kits
  
Systems  
Multiple Parameter
Microplate reader systems that used a combination of fluorescent, luminescent, and/or photoemission detectors.

Buyer Products:

  • Innovatis Systems - Cellavista Analyzer
  • Roche Diagnostics - Lumi-Imager
  
Single Parameter  
Electrochemiluminescence (ECL)
Microplate reader systems that use electrochemiluminescent (ECL) detectors.

Buyer Products:

  • Roche Diagnostics - BioVeris M-Series Analyzer
  
Sequencers  
Automated  
Nucleic Acid
Automated sequencers that employ gel electrophoresis or capillary electrophoresis to analyze nucleic acid samples.

Buyer Products:

  • Roche Diagnostics - 454 Life Sciences Genome Sequencer 20
  • Roche Diagnostics - 454 Life Sciences Genome Sequencer FLX System
  
Synthesizers  
Deoxyribonucleic Acid (DNA)/Oligonucleotides
Synthesizer system used for the identification and synthesis of nucleic acid samples.

Buyer Products:

  • MagNA Pure 96 Nucleic Acid Purification System
  
Peptides
Synthesizer systems used for the identification and synthesis of peptide samples.

Buyer Products:

  • Roche Diagnostics - Rapid Translation System
  
Thermal Cyclers  
Accessories
Supplementary products used to enhance the performance of a thermal cycler.

Buyer Products:

  • Roche Diagnostics - MagNA Pure LC
  
Systems
Thermal cycler components assembled as a single unit.

Buyer Products:

  • Roche Diagnostics - LightCycler Series Real-Time PCR Systems
  
Cellular  
Flow Cytometers  
Systems
Flow cytometer components assembled as a single unit.

Buyer Products:

  • Roche Diagnostics - xCELLigence RTCA HT System
  
Technology  
Information Technology (IT) Services  
Enterprise and Technology Consulting  
Industry-Specific IT Services  
Healthcare
IT solutions tailored and marketed for the healthcare industry.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Vantage Workflow Management Solution
  
Software  
Industry-Specific  
Healthcare/Pharma  
Business Management/Information Systems  
Patient Data Management  
Medical Image/PACS Management
Data management/PACS (Picture Archiving and Communication System) systems that are designed to store, index, access, and distribute digital medical images, such as x-rays.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso Digital Pathology Software
  
Drug Development  
Molecular Biology  
General Imaging
Software that is used to capture, analyze, store, or enhance molecular biology images that are not specific to any given imaging process.

Buyer Products:

  • Roche Diagnostics - Ventana Medical Systems Virtuoso Digital Pathology Software
  

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  MannKind Corp n/a 247.531 n/a -2.19 5,763.76 10.35 n/a
Sangamo Biosciences Inc n/a 231.365 n/a -8.23 20.37 13.65 3.11
Celldex Therapeutics Inc n/a 182.328 n/a -4.08 19.86 20.17 2.45
NewLink Genetics Corp n/a 78.307 n/a -6.83 31.63 44.13 2.13
Peregrine Pharmaceuticals Inc n/a 35.542 n/a -1.09 2.24 2.11 2.75
Buyer
  Pfizer Inc n/a 176,718.154 12.80 10.33 1.77 2.94 n/a
Johnson & Johnson n/a 176,314.376 10.12 12.61 1.55 2.65 n/a
Novartis SA n/a 145,820.038 16.87 10.02 2.47 2.53 104.31
Merck & Co Inc n/a 117,162.710 16.89 10.05 2.43 2.51 12.07
GlaxoSmithKline PLC n/a 115,869.873 15.41 11.55 3.65 2.56 n/a
Sanofi n/a 96,915.321 19.01 9.11 2.27 2.11 n/a
Abbott Laboratories n/a 96,570.037 18.80 12.30 2.46 2.42 n/a
Siemens AG n/a 79,883.093 18.86 10.56 0.96 0.79 5.30
Amgen Inc n/a 65,407.189 17.61 11.59 4.11 3.96 19.77
Target
  Medivation Inc n/a 2,897.014 n/a -97.49 35.11 19.53 35.84
MannKind Corp n/a 247.531 n/a -2.19 5,763.76 10.35 n/a
Sangamo Biosciences Inc n/a 231.365 n/a -8.23 20.37 13.65 3.11
Celldex Therapeutics Inc n/a 182.328 n/a -4.08 19.86 20.17 2.45
NewLink Genetics Corp n/a 78.307 n/a -6.83 31.63 44.13 2.13
Biosante Pharmaceuticals Inc n/a 49.503 n/a -1.68 101.37 56.36 1.30
Peregrine Pharmaceuticals Inc n/a 35.542 n/a -1.09 2.24 2.11 2.75
Generex Biotechnology Corp n/a 30.458 n/a n/a 316.72 n/a n/a
Harbor Diversified Inc n/a n/a n/a n/a n/a n/a n/a
Bavarian Nordic AS n/a n/a n/a n/a n/a n/a n/a
Agenus Inc n/a n/a n/a -10.98 n/a n/a n/a

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Synageva BioPharma Corp 96.00% n/a n/a -18.15 n/a n/a n/a
PDL Biopharma Inc 86.00% 908.665 5.75 4.45 1.41 2.36 n/a
Seattle Genetics Inc 77.00% 2,246.425 n/a -39.77 17.17 10.11 10.20
Alnylam Pharmaceuticals Inc 56.00% 455.948 n/a -8.29 5.53 7.24 2.31
PDI Inc 13.80% 126.030 n/a 22.63 0.75 0.76 1.81
Medidata Solutions Inc 11.00% 690.930 17.15 31.68 3.56 3.17 7.25
Alexandria Real Estate Equities Inc 3.60% 5,043.891 39.48 17.33 5.86 8.35 1.49
HCP Inc 3.00% 16,873.506 18.00 15.15 6.31 8.95 1.94
Exelixis Inc 0.10% 657.769 8.19 -4.79 2.42 12.37 9.58
Novartis SA n/a 145,820.038 16.87 10.02 2.47 2.53 104.31
Merck & Co Inc n/a 117,162.710 16.89 10.05 2.43 2.51 12.07
GlaxoSmithKline PLC n/a 115,869.873 15.41 11.55 3.65 2.56 n/a
Astrazeneca PLC n/a 58,543.357 7.02 7.04 1.79 2.01 94.73
Gilead Sciences Inc n/a 39,992.232 15.51 14.94 4.57 4.31 n/a
Biogen IDEC Inc n/a 33,158.436 26.97 21.87 6.45 6.07 9.95
Boston Properties Inc n/a 15,911.237 35.57 22.31 5.20 9.19 3.21
Atmel Corp n/a 3,575.399 18.12 27.25 2.10 2.26 3.69
Open Text Corp n/a 2,886.153 19.75 11.55 2.43 2.42 n/a
Target
  Bayer AG n/a 56,290.337 17.89 9.04 1.37 1.12 55.90
Fuji Film Holdings KK n/a 10,488.072 0.36 12.25 0.01 0.40 0.01
Hemacare Corp n/a 1.408 n/a n/a 0.07 n/a 0.34
New York Blood Center n/a n/a n/a n/a n/a n/a n/a
The American Red Cross n/a n/a n/a n/a n/a n/a n/a
Puget Sound Blood Center n/a n/a n/a n/a n/a n/a n/a
Blood Centers Of America n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Novartis SA n/a 145,820.038 16.87 10.02 2.47 2.53 104.31
Regeneron Pharmaceuticals Inc n/a 12,286.213 n/a 120.31 21.73 11.32 24.38
Gen-Probe Inc n/a 3,917.665 55.06 31.03 5.37 6.10 9.54
Ironwood Pharmaceuticals Inc n/a 1,272.082 n/a -9.78 18.74 12.53 7.75
Genomic Health Inc n/a 923.990 113.05 n/a 4.30 3.72 7.54
PDL Biopharma Inc n/a 908.665 5.75 4.45 1.41 2.36 n/a
Nektar Therapeutics n/a 826.104 n/a -5.49 10.57 9.87 9.61
Abaxis Inc n/a 794.944 78.94 41.56 5.08 4.49 5.10
Orasure Technologies Inc n/a 463.112 n/a -55.85 5.42 5.38 10.30
Curis Inc n/a 378.135 n/a -40.75 15.13 17.00 n/a
Grupo Casa Saba, S.A. (ADR) n/a 236.226 0.48 n/a 0.01 n/a 0.03
Heska Corporation n/a 65.963 30.63 12.50 0.94 0.77 1.36
Peregrine Pharmaceuticals Inc n/a 35.542 n/a -1.09 2.24 2.11 2.75
Response Genetics Inc n/a 29.306 n/a -4.60 1.29 1.56 n/a
Helicos BioSciences Corp n/a 6.557 n/a n/a 2.03 n/a n/a
Fleury SA n/a n/a n/a n/a n/a n/a n/a
PT Tempo Scan Pacific Tbk n/a n/a n/a n/a n/a n/a n/a
PT Enseval Putera Megatrading Tbk n/a n/a n/a n/a n/a n/a n/a
Selcuk Ecza Deposu Ticaret ve Sanayi AS n/a n/a n/a n/a n/a n/a n/a
Corporativo Fragua SAB de CV n/a n/a n/a n/a n/a n/a n/a
Profarma Distribuidora de Produtos Farmaceuticos SA n/a n/a n/a n/a n/a n/a n/a
PT Kalbe Farma Tbk n/a n/a n/a n/a n/a n/a n/a
Lonza Group AG n/a n/a n/a 6.71 n/a n/a n/a
TeaRx Ltd n/a n/a n/a n/a n/a n/a n/a
Target
  Government - United States n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Rel. Revenue % Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Merck & Co Inc n/a 117,162.710 16.89 10.05 2.43 2.51 12.07
Buyer
  International Business Machines Corp IBM n/a 240,252.905 15.25 13.36 2.25 2.22 n/a
Novartis SA n/a 145,820.038 16.87 10.02 2.47 2.53 104.31
Merck & Co Inc n/a 117,162.710 16.89 10.05 2.43 2.51 12.07
GlaxoSmithKline PLC n/a 115,869.873 15.41 11.55 3.65 2.56 n/a
Abbott Laboratories n/a 96,570.037 18.80 12.30 2.46 2.42 n/a
Amgen Inc n/a 65,407.189 17.61 11.59 4.11 3.96 19.77
Astrazeneca PLC n/a 58,543.357 7.02 7.04 1.79 2.01 94.73
Bristol Myers Squibb Co n/a 56,474.634 14.84 17.02 2.63 3.16 11.96
Eli Lilly & Co n/a 47,766.248 11.08 12.77 1.99 2.13 4.99
Gilead Sciences Inc n/a 39,992.232 15.51 14.94 4.57 4.31 n/a
Biogen IDEC Inc n/a 33,158.436 26.97 21.87 6.45 6.07 9.95
Regeneron Pharmaceuticals Inc n/a 12,286.213 n/a 120.31 21.73 11.32 24.38
Mylan Inc n/a 9,173.175 16.42 8.53 1.46 1.30 n/a
Life Technologies Corp n/a 7,882.545 17.58 10.89 2.06 2.06 n/a
Gen-Probe Inc n/a 3,917.665 55.06 31.03 5.37 6.10 9.54
Target
  Merck & Co Inc n/a 117,162.710 16.89 10.05 2.43 2.51 12.07
Bayer AG n/a 56,290.337 17.89 9.04 1.37 1.12 55.90
Fuji Film Holdings KK n/a 10,488.072 0.36 12.25 0.01 0.40 0.01
ARCA biopharma Inc n/a 5.462 n/a n/a n/a n/a 0.95
Hemacare Corp n/a 1.408 n/a n/a 0.07 n/a 0.34
Puget Sound Blood Center n/a n/a n/a n/a n/a n/a n/a
New York Blood Center n/a n/a n/a n/a n/a n/a n/a
The American Red Cross n/a n/a n/a n/a n/a n/a n/a
Blood Centers Of America n/a n/a n/a n/a n/a n/a n/a

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 68,347.2 396.6 68,743.8
Other Revenue n/a 0.1 0.1
Total Revenue 68,347.2 396.7 68,743.9
Cost of Revenue 13,313.8 200.8 13,514.6
SG&A Expense 10,836.3 361.4 11,197.7
Depreciation & Amortization 11.0 n/a 11.0
Research & Development 8,955.3 74.0 9,029.3
Interest Expense n/a n/a n/a
Other Operating Expense -1,761.1 n/a -1,761.1
Unusual Expense (Income) 943.1 38.5 981.6
Total Expenses 32,298.5 674.6 32,973.1
Operating Income 36,048.7 -278.0 35,770.8
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng -1,249.5 n/a -1,249.5
Other, Net 449.8 0.2 450.0
Income Before Taxes 13,385.1 -328.9 13,056.2
Income Taxes 2,658.0 n/a 2,658.0
Income After Taxes 10,727.1 -328.9 10,398.2
Minority Interest (IS) -225.3 n/a -225.3
Net Income - Excl. Xord. Items 10,501.8 -328.9 10,172.9
Net Income - Incl. Xord. Items 10,501.8 -328.9 10,172.9
Income Avail. to Common 10,501.8 -328.9 10,172.9
Share Items
Basic Avg. Shares Outstanding 848.0 147.6 995.6
Basic EPS - Excl. Xord. Items 12.37 -2.25 10.22
Basic EPS - Incl. Xord. Items 6.80 -2.25 10.22
Full Dilution Adjustment -1.0 n/a -1.0
Fully Diluted Shares Outstanding 849.2 147.6 996.8
F.D. EPS - Excl. Xord. Items 6.78 -2.25 10.21
F.D. EPS - Incl. Xord. Items 6.78 -2.25 10.21
Dividends Per Common Share 6.80 n/a 6.80
Balance Sheet
Assets
Cash and Equivalents 3,854.0 337.7 4,191.7
ST Investments 7,433.0 159.9 7,592.9
Accounts Receivable 9,799.0 41.7 9,840.7
Inventory 5,060.0 74.0 5,134.0
Prepayments and Advances n/a 21.1 21.1
Other Current Assets 2,086.0 n/a 2,086.0
Current Assets 28,232.0 634.2 28,866.2
PPE n/a 323.0 323.0
Accum D&A n/a -86.0 -86.0
PPE, Net 16,201.0 237.0 16,438.0
Goodwill & Intangibles 12,969.0 n/a 12,969.0
Long Term Investments 384.0 61.6 445.6
Other Assets n/a n/a n/a
Other LT Assets 3,790.0 9.2 3,799.2
Total Assets 61,576.0 942.0 62,518.0
Liabilities
Accounts Payable 2,053.0 9.5 2,062.5
Payable/Accrued n/a n/a n/a
Accrued Expenses 7,511.5 56.4 7,567.9
ST Debt n/a n/a n/a
Curr Port of LTD & Cap Lease Oblg 3,394.0 4.9 3,398.9
Other (Current) Liabilities 10,763.0 15.6 10,778.6
Current Liab. 16,210.0 86.3 16,296.3
LT Debt 23,459.0 542.0 24,001.0
Capitalized Lease Obligations n/a 26.9 26.9
Total LT Debt 23,459.0 568.9 24,027.9
Minority Interest (BS) 2,387.0 n/a 2,387.0
Deferred Taxes 604.0 n/a 604.0
Other LT Liab. 6,821.0 7.2 6,828.2
Total Liabilities 49,481.0 662.4 50,143.4
Shareholders Equity
Common Stock 160.0 0.1 160.1
Additional Paid in Capital n/a 1,943.9 1,943.9
Retained Earnings 17,369.0 -1,664.7 15,704.3
Other Equity -5,434.0 0.2 -5,433.8
Total Equity 12,095.0 279.5 12,374.5
Total Liab. & Equity 61,576.0 942.0 62,518.0
Shares Outstanding 862.6 154.0 1,016.6
Cash Flow
Operating Cash Flow
CF Net Income 9,544.0 -330.0 9,214.0
CF Depreciation 1,848.0 40.1 1,888.1
CF Amortization 520.0 n/a 520.0
CF Deferred Taxes n/a n/a n/a
Other Non-Cash Items 4,120.8 123.8 4,244.6
Change in Working Capital 4,910.4 -30.4 4,880.0
Total Cash From Operating Activities 20,943.2 -196.4 20,746.8
Investing Cash Flow (not calculated)
Capital Expenditures -3,450.8 -25.6 -3,476.4
Other Investing Cash Flows 5,803.7 0.5 5,804.2
Total Cash From Investing Activities 2,352.9 -25.2 2,327.8
Financing Cash Flow (not calculated)
Dividends Paid -12,710.8 n/a -12,710.8
Purchase Or Sale of Stock n/a 8.4 8.4
Purchase and Retirement of Debt -2,136.1 -4.1 -2,140.2
Other Financing Cash Flow -2,310.6 0.8 -2,309.8
Total Cash From Financing Activities -20,903.5 3.9 -20,899.5
Exchange Rate Effects -123.7 n/a -123.7
Net Change in Cash 2,269.0 -217.6 2,051.4
Cash Taxes Paid 3,924.3 n/a 3,924.3
Cash Interest Paid 3,084.9 26.1 3,111.0