Summary

Other Scenarios:

Buyer: Roche Holding Ltd. (ADR) (RHHBY) Last Price: 91.15 Market Cap.: 157.25B
Target: Schering AG (ADR) (SHR) Last Price: 120.31 Market Cap.: 22.96B

Lines of Business Summary:

Product Summary:

Overlap & Complementary Sectors

Sector Buyer Target # of Focused Companies
*Healthcare 870
Biopharmaceuticals 329
Medical Devices 247
Scientific Products   40

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Sample Products in Similar Lines of Business

Sample Products in Complementary Lines of Business

Buyer (Total: 231)
  • Xolair (Omalizumab)
  • Cardene (Nicardipine Hydrochloride)
  • Dilatrend (Carvedilol)
  • Demadex (Torsemide)
Target (Total: 79)
  • Cathepsin S Inhibitor
  • Berlex Betapace/Betapace AF (Sotalol Hydrochloride)
  • Berlex Betaseron (Interferon Beta-1b)
  • Berlex AGT-MI (FGF-4 Gene Therapy)
Buyer
  • Roche Diagnostics AVL Compact 1-3
  • Roche Diagnostics AVL 988 Series
  • Roche Diagnostics OMNI Series
  • Roche Diagnostics AVL 9180 Series
Target
  • Gadofluorine Derivative
  • Berlex Vasovist (Gadofosveset)
  • Medrad Mark V ProVis Injection System
  • Medrad Mark Series

Business Relationship Summary:

Top Key Suppliers

Top Key Customers

Buyer (Total: 42)
  • Aspreva Pharmaceuticals Corporation (ASPV)
  • Emisphere Technologies Inc. (EMIS)
  • deCODE genetics, Inc. (DCGN)
  • PDL BioPharma Inc. (PDLI)
Target (Total: 15)
  • Advanced Magnetics, Inc. (AMAG)
  • Biogen Idec Inc. (BIIB)
  • Serono S.A. (ADR) (SRA)
  • Millennium Pharmaceuticals, Inc. (MLNM)
Buyer (Total: 13)
  • Applera Corporation (ABI)
  • PDL BioPharma Inc. (PDLI)
  • MDS Inc. (USA) (MDZ)
  • IDEXX Laboratories, Inc. (IDXX)
Target (Total: 5)
  • Millennium Pharmaceuticals, Inc. (MLNM)
  • Cotherix, Inc (CTRX)
  • Sonus Pharmaceuticals, Inc. (SNUS)
  • Favrille, Inc. (FVRL)

Key Financial Summary:

Key Metrics

  Buyer Target
Number of Employees 68,218 23,098
Revenue Per Employee 479,624.4 308,724.3
Total Revenue 15,661.8 1,779.7
Total Expenses 11,081.4 1,566.3
Other Revenue 0.0 0.0
Cost of Revenue 3,893.2 415.4
SG&A Expense 4,955.2 738.0
Research & Development 2,416.9 310.0
Other Operating Expense -573.6 102.9
Operating Income 4,580.4 213.4
Unusual Income 0.0 0.0
LT Debt to Capital 18.78 5.88
Fwd P/E 24.82 n/a
Fwd P/Rev n/a n/a
Book Value 27,367.3 4,297.3
Curr Portion of LTD/Cap Lease 271.4 30.1

Individual Company Summary

Focused

Buyer

Focused (): *Healthcare > Biopharmaceuticals

Target

Focused (): *Healthcare > Biopharmaceuticals

Business Description

Buyer

Roche Holding Ltd. is in the business of pharmaceuticals and diagnostics. Its pharmaceutical division offers a portfolio of medicines in various therapeutic areas, including cancer, human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), hepatitis C, transplantation, dermatology and influenza. The Company's diagnostic division supplies an array of testing products and services to researchers, physicians, patients, hospitals and laboratories worldwide. Its products and services address prevention, diagnosis, treatment and the monitoring of diseases. The Company has operations in approximately 150 countries. During the year ended December 31, 2004, the Company has 64 new molecular entities in the research and development pipeline. In 2004, the Company's first deoxyribonucleic acid (DNA) chip-based test introduced to support more personalized therapy.

Target

Schering AG is a global research-based company engaged in the discovery, development, manufacture, marketing and sale of pharmaceutical products. The Company operates eight research and development centers in Europe, the United States and Japan, produce products in facilities located in Europe, the United States, Latin America and Asia, and markets and sells its products in over 100 countries worldwide. Its research and development efforts are primarily concentrated on the commercialization of technologies for unmet medical needs in its four core business areas: Gynecology & Andrology, Diagnostic Imaging, Specialized Therapeutics and Oncology. The Company derived approximately 38% of its net sales, during the year ended December 31, 2005, from sales of four key products: Betaferon, sold in the United States and Canada under the Betaseron trademark (16% of net sales); Yasmin (11%); Magnevist (6%), and Ultravist (5%). Bayer AG gained control of a total of 88% of the Company in June 2006.

Deal Summary

Key Ratios

  Buyer Target
Gross Margin % 73.8 76.83
Operating Margin % 24.41 15.61
Quick Ratio 3.01 1.76
Current Ratio 3.75 2.31
Coverage Ratio 0.03 0.02
Total Assets 54,020.5 7,378.4
Return on Equity % 19.31 17.64
Return on Assets % 9.72 10.27
Cash+ ST Inv. Per Share 9.46 8
Total Debt 7,530.9 298.7
Total Debt to Equity % 27.69 6.95
Total Debt to Tangible Equity % 42.91 8.61
Debt to Asset % 13.94 4.05

Product Summary

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies
The Allergies Subsector includes therapeutics that treat exaggerated immune reaction induced by exposure to a foreign substance.
Cardiovascular System
The Cardiovascular System Subsector includes therapeutics that treat disorders affecting the heart and blood vessels.
Dermatology
The Dermatology Subsector includes therapeutics that treat disorders affecting the skin.
Digestive System
The Digestive System Subsector includes therapeutics that treat disorders affecting the digestive system.
Endocrinology/Metabolism
The Endocrinology/Metabolism Subsector includes therapeutics that treat metabolic disorders and conditions resulting from the dysfunction of hormone secreting glands.
Hematology
The Hematology Subsector includes therapeutics that treat blood-based diseases and disorders.
Immunology
The Immunology Subsector includes therapeutics that treat disorders affecting the immune system.
Infectious Diseases
The Infectious Diseases Subsector includes therapeutics that treat diseases caused by the invasion and reproduction of microorganisms in the body.
Musculoskeletal System
The Musculoskeletal System Subsector includes therapeutics that treat disorders of the bones, joints, ligaments, tendons, and soft tissue involved with them.
Neurology
The Neurology Subsector includes therapeutics that treat disorders of the central nervous system, including the brain, spinal cord, and nerves.
Obstetrics/Gynecology
The Obstetrics/Gynecology Subsector includes therapeutics that treat female genital disorders, pregnancy, and childbirth.
 
Oncology
The Oncology Subsector includes therapeutics that treat and manage various types of cancer and related complications.
Ophthalmology
The Ophthalmology Subsector includes therapeutics that treat eye disorders, infections, inflammations and irritations.
 
Pain Management
The Pain Management Subsector includes therapeutics that treat and management pain.
 
Respiratory System
The Respiratory System Subsector includes therapeutics that treat disorders affecting both the upper and lower respiratory tract, including the nose, throat, larynx, trachea, bronchi, and lungs.
Surgery
The Surgery Subsector includes therapeutics that treat complications associated with surgical procedures.
 
Toxicology
The Toxicology Subsector includes therapeutics that treat harmful effects from exposure to toxic substances; narcotics, nicotine and alcohol withdrawal therapeutics are also included in this sector.
 
Transplantation
The Transplantation Subsectors includes therapeutics that treat rejection and infection associated with tissue transplantation into the human body.
Urology
The Urology Subsector includes therapeutics that treat diseases of the kidney, urinary tract, bladder, and the male reproductive system.
Weight Management
The Weight Management Subsectors includes herapeutics that treat and manage weight disorders.
 
Wound Management
The Wound Management Subsector includes therapeutics that treat cuts, abrasions, and burns from trauma or diseases.
 
Medical Devices
Cardiology
The Cardiology Subsector includes medical devices that diagnose, monitor, and treat diseases affecting the heart and proximal blood vessels. Common devices include vital sign monitors, cardiac defibrillators, pacemakers, and other surgical equipment.
 
Clinical Diagnostics
The Clinical Diagnostics Subsector includes medical devices that analyze human body specimens within a medical setting. These devices, including equipment, biological and chemical reagents are primarily used for the diagnosis of diseases.
 
Neurology
The Neurology Subsector includes medical devices that diagnose, monitor and treat neurological disorders.
 
Oncology
The Oncology Subsector includes medical devices that detect and treat cancers.
 
Radiology
The Radiology Subsector includes medical devices that generate images of internal physiology.
 
Urology
The Urology Subsector includes medical that diagnose and treat urinary tract and male reproductive disorders.
 
Vascular
The Vascular Subsector includes medical devices that diagnose and treat of conditions affecting the blood vessels.
 
Scientific Products  
Analytical Instruments
The Analytical Instruments Subsector includes scientific products that determine the quantitative and qualitative nature of biochemical samples.
 
Bioanalytical Instruments
The Bioanalytical Instruments Subsector includes scientific products, devices and apparatuses that determine the quantitative and qualitative nature of a biological samples.
 
Consumables
The Consumables Subsector includes chemicals, reagents, standards, media, and disposable labware that are normally depleted or worn out by continuous use.
 
General Laboratory Equipment
The General Laboratory Equipment Subsector includes products that are used during routine laboratory procedures, such as sample preparation, processing, storage, cleaning, and purification.
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Product Details

Sector Buyer Target
*Healthcare
Biopharmaceuticals
Allergies
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for treatment of allergic reactions in early stages of clinical research where human subject is involved.

Buyer Products:

  • Xolair (Omalizumab)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of allergic reactions in very early stages of research where no human subject is involved.

Target Products:

  • Cathepsin S Inhibitor
 
Upper Respiratory  
Monoclonal Antibodies
Therapeutics that treat allergic reactions by specifically binding and inhibiting inflammatory substances.

Buyer Products:

  • Xolair (Omalizumab)
 
Cardiovascular System
Heart Disorders
Angina  
Calcium Channel Blocking Agents
Therapeutics that treat chest pains by preventing the entry of calcium into heart muscle cells.

Buyer Products:

  • Cardene (Nicardipine Hydrochloride)
 
Arrhythmia  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat abnormal rhythm of the heart beat by inhibiting the stimulation of beta adrenergic receptors of the heart muscle.

Target Products:

  • Berlex Betapace/Betapace AF (Sotalol Hydrochloride)
 
Heart Failure (HF)  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat the ineffective pumping of the heart by blocking beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Dilatrend (Carvedilol)
 
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that treat the excessive accumulation of fluids by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Demadex (Torsemide)
  • Bumex (Bumetanide)
 
Myocardial Infarction (MI)  
Beta Adrenergic Receptor Blocking Agents (Beta Blockers)
Therapeutics that treat irreversible damage to the heart muscle by blocking the beta adrenergic receptors of the heart muscle.

Buyer Products:

  • Dilatrend (Carvedilol)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • BO-653 (Antioxidant)
  • TF Fab (Monoclonal Antibody Fragment)
  • R639/SPP301 (Endothelin Receptor A Antagonist)
  • AXV034343 (Endothelin A Receptor Antagonist)

Target Products:

  • Berlex Betaseron (Interferon Beta-1b)
  • Berlex AGT-MI (FGF-4 Gene Therapy)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of heart and circulatory system disorders in very early stages of research where no human subject is involved.

Target Products:

  • Cathepsin S Inhibitor
 
Vascular Disorders
Deep Vein Thrombosis (DVT)  
Anticoagulating Agents (Anticoagulants)  
Platelet Aggregation Inhibitors  
Adenosine Diphosphate (ADP) Inhibitors
Therapeutics that treat/prevent thrombosis by selectively inhibiting the binding of adenosine diphosphate (ADP) to its platelet receptor, thereby inhibiting platelet aggregation.

Buyer Products:

  • Ticlid (Ticlopidine Hydrochloride)
 
Hypertension  
Calcium Channel Blocking Agents
Therapeutics that treat high blood pressure by blocking the beta adrenergic receptors of the heart muscle and increasing the excretion of sodium ions, potassium ions, and water through urine.

Buyer Products:

  • Cardene (Nicardipine Hydrochloride)
  • Cardene SR (Nicardipine Hydrochloride)
 
Loop Diuretic Agents
Therapeutics that treat high blood pressure by increasing the excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Demadex (Torsemide)
 
Stroke  
Anticoagulating Agents (Anticoagulants)  
Platelet Aggregation Inhibitors  
Adenosine Diphosphate (ADP) Inhibitors
Therapeutics that prevent or treat damage to nerve cells of the brain by preventing platelets from clumping together.

Buyer Products:

  • Ticlid (Ticlopidine Hydrochloride)
 
Thromboembolism  
Anticoagulating Agents (Anticoagulants)  
Thrombin Inhibitors
Therapeutics that treat the obstruction of a blood vessel by preventing blood clots from forming.

Target Products:

  • Berlex Refludan (Lepirudin)
 
Dermatology
Acne
Rosacea  
Azelaic Acid
Therapeutics that treat and prevent rosacea caused by bacteria.

Target Products:

  • Berlex Finacea (Azelaic Acid)
 
Vulgaris  
Retinoids/Vitamin A Analogs
Therapeutics that treat acne by helping in cell differentiation as well as prevent cell proliferation.

Buyer Products:

  • Roaccutane/Accutane (Isotretinoin)
 
Lesion/Scaling Disorders  
Psoriasis  
Monoclonal Antibodies
Therapeutics that treat psoriasis by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Buyer Products:

  • Raptiva (Efalizumab)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skin disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • BAL4079 (9-Cis Retinoic Acid)
  • BAL2299 (Nuclear Receptor Modulator)
  • BCX-4208 (Second-Generation PNP Inhibitor)

Target Products:

  • CRA-028129 (Cathepsin S Inhibitor)
  • Berlex Tisocalcitate (Calcitriol Analog)
Digestive System
Gastrointestinal Tract Disorders
Gastroesophageal Disorders  
Nausea/Vomiting  
Serotonin Receptor Antagonists
Therapeutics that treat nausea and vomiting by blocking the serotonin receptors.

Buyer Products:

  • Kytril (Granisetron Hydrochloride)
 
Intestinal Disorders  
Inflammatory Bowel Disease (IBD)  
Crohn`s Disease  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat Crohn's Disease by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Stomatognathic Disorders  
Mucositis  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat mucositis by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Liver Disorders  
Cirrhosis  
Complications  
Edema  
Loop Diuretic Agents
Therapeutics that prevent edema by excretion of sodium, potassium, chloride ions, and water in urine.

Buyer Products:

  • Bumex (Bumetanide)
  • Demadex (Torsemide)
 
Hepatitis  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
 
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections by preventing viral replication, stimulating the immune system to also fight the virus, and inhibits replication of viral DNA by incorporating themselves into growing viral DNA stands.

Buyer Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1270 (Levovirin)
  • R1124 (GPCR Modulator)
  • GM -611 (Motilin Agonist)
  • R1479 (Polymerase Inhibitor)
  • R440 (Cell Cycle Inhibitor)
  • R1068 (GPCR Modulator)
  • R1518 (Levovirin)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of digestive disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1626 (Polymerase Inhibitor)
  • ITMN-191 (Protease Inhibitor)
  • R1541 (Integrin Antagonist)
 
Endocrinology/Metabolism
Diabetes  
Non-Insulin Dependent Diabetes Mellitus (NIDDM)/Type 2 Diabetes  
Peroxisome Proliferator-Activated Receptor Agonists (PPAR Agonists)
Products that sensitizes organs to insulin.

Buyer Products:

  • R483 (Insulin Sensitizer)
 
Intermediary Metabolism Disorders  
Gout  
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that counteract or suppress inflammation preventing cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Parathyroid Gland Disorders  
Hyperparathyroidism (HPT)  
Vitamin D Analogs
Therapeutics that act similar to Vitamin D.

Buyer Products:

  • Rocaltrol (Calcitriol)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1439 (Nuclear Receptor Modulator)
  • R1440 (Enzyme Modulator)
  • R1438 (Enzyme Inhibitor)
  • BIM 51077 (GLP-1 Analogue)
 
Reproductive Disorders  
Hypoestrogenism  
Hormonal Treatments  
Estrogens
Therapeutics that are female sex hormones.

Target Products:

  • Berlex Climara (Estradiol Transdermal System)
 
Hypogonadism  
Female  
Hormonal Treatments  
Estrogens
Therapeutics that are female sex hormones.

Target Products:

  • Berlex Climara (Estradiol Transdermal System)
 
Menopause  
Estrogens
Therapeutics that are female sex hormones.

Target Products:

  • Berlex Climara (Estradiol Transdermal System)
 
Estrogens/Progestins
Therapeutics that are mixture of two female sex hormones that are important for the development of the female reproductive system.

Target Products:

  • Berlex Climodien 1/2 (Estradiolvalerate/Dienogest)
  • Berlex Climara Pro (Levonorgestrel/Estradiol Transdermal)
  • Berlex Angeliq (Drospirenone/Estradiol)
 
Progestins
Therapeutics that are female sex hormones.

Target Products:

  • Berlex Levonorgestrel Intrauterine System
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of endocrinology disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1499 (Enzyme Inhibitor)
  • Glucokinase Enzyme
  • R1593 (Nuclear Receptor Modulator)
  • R1498 (Nuclear Receptor Modulator)
 
Hematology
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1516
  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
 
Red Blood Cell (RBC) Disorders  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat conditions characterized by reduced delivery of oxygen to body tissues by stimulating red blood cell production.

Buyer Products:

  • NeoRecormon (Epoetin Beta)
  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of hematological disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1593 (Nuclear Receptor Modulator)
 
Serum Factor Disorders  
Hypocalcemia  
Vitamin D Analogs
Therapeutics that treat hypocalcemia by increasing serum levels of calcium, as well as helping the bone calcification process.

Buyer Products:

  • Rocaltrol (Calcitriol)
 
White Blood Cell (WBC) Disorders  
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat neutropenia by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Immunology
Autoimmune Disorders
Arthritis  
Rheumatoid Arthritis (RA)  
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • Rituxan (Rituximab)
  • R1569/MRA (Tocilizumab)
 
Inflammatory Bowel Disease (IBD)  
Crohn`s Disease  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat Crohn's Disease by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Multiple Sclerosis (MS)  
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that downregulates the antibody response of the immune system.

Target Products:

  • Berlex Betaseron (Interferon Beta-1b) For SC Injection
  • Berlex Betaseron (Interferon Beta-1b)
 
Psoriasis  
Monoclonal Antibodies
Therapeutics that treat psoriasis by binding to certain receptors on antigens associated with the disease, thus modulating the immune reaction.

Buyer Products:

  • Raptiva (Efalizumab)
 
Immune Deficiency Disorders  
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Buyer Products:

  • Fuzeon (Enfuvirtide)
 
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • Hivid (Zalcitabine)
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Fortovase (Saquinivir)
  • Invirase (Saquinavir Mesylate)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Fortovase (Saquinivir)
  • R1594 (Anti-CD20 Molecule )
  • R1599
  • BAL2299 (Nuclear Receptor Modulator)
  • R1295 (Integrin Antagonist)
  • R1487 (Kinase Inhibitor)
  • R724/T-1249 (Fusion Inhibitor)
  • R944 (Protease Inhibitor)
  • Raptiva (Efalizumab)
  • R1503 (Kinase Inhibitor)
  • BCX-4208 (Second-Generation PNP Inhibitor)

Target Products:

  • Berlex Tisocalcitate (Calcitriol Analog)
  • Berlex Campath (Alemtuzumab)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of immune disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1628
  • R1541 (Integrin Antagonist)
  • R1495 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • BR3-FC
  • CLIP (Class II Associated Invariant Chain Peptide)

Target Products:

  • Cathepsin S Inhibitor
Infectious Diseases
Bacterial  
Antibacterial Agents  
Broad Spectrum  
Antibiotics  
Cephalosporin Derivatives
Therapeutics that treat a wide variety of infections by inhibiting bacterial cell wall synthesis.

Buyer Products:

  • Rocephin (Ceftriaxone Sodium)
 
Sulfonamides
Therapeutics that treat a wide variety of bacterial infections by inhibiting folic acid synthesis.

Buyer Products:

  • Gantrisin (Sulfisoxazole)
 
Narrow Spectrum  
Digestive System  
Shigellosis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat an infection of the intestines caused by Shigella by inhibiting folic acid synthesis.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Otolaryngology (Ear/Nose/Throat)  
Otitis Media  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the middle ear inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Respiratory System  
Bronchitis  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections leading to inflammation of the bronchi in the lungs by inhibiting certain enzymes that are vital for bacterial DNA transcription and repair.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Urology  
Urinary Tract Infections (UTI)  
Antibacterial Agents (Antibiotics)  
Diaminopyrimidines/Sulfonamides
Therapeutics that treat bacterial infections of the urinary tract by inhibiting dihydrofolate reductase resulting in decreased bacterial nucleic acid/protein production.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Mycological (Fungal)  
Antifungal Agents  
Narrow Spectrum  
Respiratory System  
Pneumocystis Carinii Pneumonia (PCP)  
Dihydrofolate Reductase Inhibitors/Dihydropteroate Synthetase Inhibitors
Therapeutics that treat infections of the lungs of immunocompromised patients caused by Pneumocystis carinii by interfering with folic acid synthesis and growth of organism.

Buyer Products:

  • Bactrim (Trimethoprim/Sulfamethoxazole)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1518 (Levovirin)
  • R1270 (Levovirin)
  • CS-023 (Prenteral Crbapenem)
  • BAL8557 (Antifungal Agent)
  • BAL5788 (Antibiotic)
  • R724/T-1249 (Fusion Inhibitor)
  • R944 (Protease Inhibitor)
  • R1479 (Polymerase Inhibitor)
  • Fortovase (Saquinivir)
  • R1461 (Fusion Protein)
  • R1558
 
Protozoal  
Antiprotozoal Agents  
Narrow Spectrum  
Malaria  
Aminoquinolines
Therapeutics that treat parasitic infections caused by Plasmodia in red blood cells by inhibiting parasite growth.

Buyer Products:

  • Lariam (Mefloquine Hydrochloride)
 
Diaminopyrimidines/Sulfonamides
Therapeutics that treat infections due to parasites by inhibiting folic acid synthesis and also blocking the action of the dihydrofolate enzyme.

Buyer Products:

  • Fansidar (Sulfadoxine/Pyrimethamine)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of infectious diseases in very early stages of research where no human subject is involved.

Buyer Products:

  • ITMN-191 (Protease Inhibitor)
  • R1495 (Non-Nucleoside Reverse Transcriptase Inhibitor)
  • BAL8349 (Antifungal Agent)
  • R1626 (Polymerase Inhibitor)
  • Tamiflu (Oseltamivir)

Target Products:

  • Human Papilloma Virus Vaccine
Viral  
DNA Viruses  
Hepadnavirus  
Hepatitis B  
Chronic  
Interferons
Therapeutics that treat viral infections characterized by inflammation of the liver for more than six months with natural proteins that have antiviral activity.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
 
Herpesvirus  
Cytomegalovirus (CMV)  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
 
RNA Viruses  
Flavivirus  
Hepatitis C  
Chronic  
Interferons
Therapeutics that treat hepatitis by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Pegasys (Pegylated Interferon Alfa-2a)
  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Interferons/Nucleoside Analogs
Therapeutics that treat viral infections characterized by long term inflammation of the liver by enhancing the immune system and by inhibiting replication of viral DNA.

Buyer Products:

  • Pegasys/Copegus (Pegylated Interferon Alfa-2a/Ribavirin)
 
Orthomyxovirus  
Influenza A  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza A virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Tamiflu (Oseltamivir)
 
Influenza B  
Neuraminidase Inhibitors
Therapeutics that treat viral infections of the respiratory tract caused by Influenza B virus by preventing the release of new viruses from infected cells.

Buyer Products:

  • Tamiflu (Oseltamivir)
 
Retrovirus  
Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS)  
Fusion Inhibitors
Therapeutics that manage HIV by inhibiting the fusion of the HIV into human host cells where it can replicate.

Buyer Products:

  • Fuzeon (Enfuvirtide)
 
Nucleoside Reverse Transcriptase Inhibitors (NRTI)
Therapeutics that help manage HIV by inhibiting the action of reverse transcriptase, an enzyme necessary for the DNA synthesis on a RNA template.

Buyer Products:

  • Hivid (Zalcitabine)
 
Protease Inhibitors
Therapeutics that help manage HIV by binding to and blocking the action of HIV protease, an enzyme necessary for viral replication.

Buyer Products:

  • Invirase (Saquinavir Mesylate)
  • Fortovase (Saquinivir)
 
Musculoskeletal System
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Rituxan (Rituximab)
  • Raptiva (Efalizumab)
  • R1487 (Kinase Inhibitor)
  • R1295 (Integrin Antagonist)
  • R1164
  • R1594 (Anti-CD20 Molecule )
  • R1599
  • ED-71 (Vitamin D Derivative)
  • CHS 13340 (Recombinant Parathyroid Hormone)
  • R1503 (Kinase Inhibitor)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of skeletal system disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • BR3-FC
  • R1628

Target Products:

  • Cathepsin S Inhibitor
Skeletal Disorders
Bone Disorders
Osteoporosis
Hormonal Treatments  
Estrogens
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Target Products:

  • Berlex Menostar (Estradiol)
  • Berlex Climara (Estradiol Transdermal System)
 
Estrogens/Progestins
Therapeutics that treat osteoporosis by providing female hormones which results in a decrease in the rate of bone loss due to osteoclasts.

Target Products:

  • Berlex Climara Pro (Levonorgestrel/Estradiol Transdermal)
 
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts.

Buyer Products:

  • Boniva (Ibandronate Biphosphonate)
 
Selective Estrogen Receptor Modulators (SERM)
Therapeutics that treat osteoporosis by preventing loss of bone mass due to osteoclasts while not stimulating the endometrial lining of the uterus.

Buyer Products:

  • Evista (Raloxifene Hydrochloride)
 
Joint Disorders  
Ankylosing Spondylitis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Gouty Arthritis  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by inhibiting cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Osteoarthritis (OA)  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat inflammation by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Rheumatoid Arthritis (RA)  
Analgesics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain associated with chronic inflammation of the joints by blocking cyclooxygenase activity.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
 
Immunotherapy  
Monoclonal Antibodies
Therapeutics that treat rheumatoid arthritis by interfering with specific immune pathways implicated in the progression of the disease.

Buyer Products:

  • R1569/MRA (Tocilizumab)
  • Rituxan (Rituximab)
 
Neurology
Neurological Disorders  
Epilepsy  
Primary Generalized Seizures  
Absence (Petit Mal)  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Petit Mal Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Akinetic Pattern  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Akinetic Pattern Seizures by preventing the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Myoclonic  
Adjunctive Therapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevent nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Monotherapy  
Gamma-Aminobutyric Acid (GABA) Reuptake Inhibitors
Therapeutics that treat Myoclonic Seizures by inhibiting the uptake of molecules that prevents nerve activation.

Buyer Products:

  • Klonopin (Clonazepam)
 
Neuromuscular Disorders  
Multiple Sclerosis (MS)  
Interferons
Therapeutics that treat multiple sclerosis with a recombinant human protein that down regulates the antibody response of the immune system.

Target Products:

  • Berlex Betaseron (Interferon Beta-1b)
  • Berlex Betaseron (Interferon Beta-1b) For SC Injection
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • MT 500 (GPCR Modulator)
  • R1204 (GPCR Modulator)
  • R673 (GPCR Modulator)
  • Rituxan (Rituximab)

Target Products:

  • Berlex Spheramine
  • Berlex Campath (Alemtuzumab)
Psychiatric Disorders
Anxiety  
Generalized Anxiety Disorder (GAD)  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat anxiety by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Valium (Diazepam)
 
Panic Disorder  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat panic disorder by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Klonopin (Clonazepam)
 
Mood Disorders  
Premenstrual Dysphoric Disorders  
Estrogens/Progestins
Therapeutics that treat premenstrual dysphoric disorders by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus.

Target Products:

  • Berlex YAZ (Drospirenone/Ethinyl Estradiol)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of nervous system and mental disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1067 (GPCR Modulator)
  • R1450
  • R641
  • R1576 (GPCR Modulator)
 
Obstetrics/Gynecology  
Child Birth/Pregnancy  
Prevention (Contraception)  
Contraceptives (Birth Control)  
Estrogens/Progestins
Therapeutics that prevent conception by decreasing the secretion of gonadotropin-releasing hormone in the hypothalamus, resulting in an anti-ovulatory effect.

Target Products:

  • Berlex Tri-Levlen 21/Tri-Levlen 28 (Levonorgestrel/Ethinyl Estradiol Tablets)
  • Berlex Yasmin (Drospirenone/Ethinyl Estradiol)
  • Berlex E2/DNG Pill (Estradivalerate/Dienogest)
  • Berlex FC Patch (Gestodene/Ethinyl Estradiol)
  • Berlex YAZ (Drospirenone/Ethinyl Estradiol)
  • Berlex Levlen 21/Levlen 28 (Levonorgestrel/Ethinyl Estradiol Tablets)
  • Berlex Levlite (Levonorgestrel/Ethinyl Estradiol Tablets)
 
Progestins
Contraceptive Therapeutics that are female sex hormone necessary for the development of the female reproductive system

Target Products:

  • Berlex Mirena (Levonorgestrel-Releasing Intrauterine Device)
 
Female Genital Disorders  
Endometriosis  
Gonadotropin Releasing Hormone (GnRH) Agonists
Therapeutics that treat endometriosis by suppressing the secretion of luteinizing hormone which results in decreased testosterone concentrations.

Target Products:

  • Berlex Endometrion (Dienogest)
 
Ovarian  
Hypogonadism  
Hormonal Treatments  
Estrogens
These are female sex hormones.

Target Products:

  • Berlex Climara (Estradiol Transdermal System)
 
Vulvovaginal  
Atrophy  
Hormonal Treatments  
Estrogens
Therapeutics that treat disorders characterized by thinning of the vaginal walls with the female sex hormone estrogen.

Target Products:

  • Berlex Climara (Estradiol Transdermal System)
 
Oncology
Breast Cancer
Localized  
Monoclonal Antibodies
Therapeutics that treat breast cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
  • Herceptin (Trastuzumab)
 
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage breast cancers that have spread beyond their original tumor site by inhibiting the production of DNA.

Buyer Products:

  • Xeloda (Capecitabine)
 
Antimicrotubule Agents
Therapeutics that treat and manage cancers of the breast that have spread beyond their original tumor site by blocking the normal function of microtubules, thus inhibiting cell division.

Target Products:

  • TOCOSOL Paclitaxel (S-8184)
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of breast cancer cells and inhibit the cancer cells' growth and induce their death.

Buyer Products:

  • Herceptin (Trastuzumab)
  • Avastin (Bevacizumab)
 
Dermatology  
Kaposi`s Sarcoma  
Interferons
Therapeutics that treat and manage cancers of spindle cells by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Digestive System
Colon Cancer/Colorectal Cancer
Localized  
Vascular Endothelial Growth Factor Receptor Inhibitor (VEGFR)
Therapeutics that treat colorrectal cancer by binding specifically to the tyrosine kinase domain of vascular endothelial growth factor receptor (VEGFR) and inhibiting the formation of blood vessels around tumor cells.

Target Products:

  • Berlex PTK787 (Vatalanib)
 
Metastatic
Antimetabolite Agents  
Pyrimidine Analogs
Analogs of the pyrimidine bases of nucleic acids that treat and manage colorectal tumors that have spread beyond their original tumor site by inhibiting the production of DNA.

Buyer Products:

  • Xeloda (Capecitabine)
 
Monoclonal Antibodies
Therapeutics that treat colorectal cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
 
Vascular Endothelial Growth Factor Receptor Inhibitor (VEGFR)  
Pancreatic Cancer  
Metastatic  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the pancreas by blocking the action of tyrosine kinase enzyme through switching off the signals from the epidermal growth factor receptors, which promote cell growth.

Buyer Products:

  • Tarceva (Erlotinib)
 
Hematology
Leukemia
Lymphoid
Chronic
Hairy Cell  
Interferons
A recombinantly produced protein normally produced by the body to fight viral infection used to treat and manage a slowly progressing cancer of lymphoid cells characterized by numerous irregular cytoplasmic projections.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Lymphocytic (CLL)
Antimetabolite Agents  
Adenosine Deaminase Inhibitors
Therapeutics that treat and manage slowly progressing cancers of lymphocytic cells by inhibiting the transformation of deoxyadenosine into deoxyinosine thereby impairing DNA synthesis as well as leaving the cancer cells unable to repair single stranded DNA breaks.

Target Products:

  • Berlex Fludara (Fludarabine Phosphate)
 
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of leukemia cells and thereby induce their death.

Buyer Products:

  • Rituxan (Rituximab)

Target Products:

  • Berlex Campath (Alemtuzumab)
Myeloid  
Acute  
Promyelocytic (APL)  
Retinoids/Vitamin A Analogs
Therapeutics that treat acute promyelocytic leukemia by helping in cell differentiation as well as decreasing proliferation of cells.

Buyer Products:

  • Vesanoid (Tretinoin)
 
Chronic  
Myelogenous (CML)  
Interferons
Therapeutics that treat and manage slowly progressing cancers of myelogenous cells by providing a naturally occurring protein that stimulates the immune system.

Buyer Products:

  • Roferon-A (Interferon Alfa-2a, Recombinant)
 
Palliative Agents  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat neutropenia and other cancer related conditions by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Lymphoma
Hodgkin`s Disease  
Palliative Agents  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat neutropenia and other cancer related conditions of lymphoma characterized by the presence of Reed-Sternberg cells by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Non-Hodgkin`s Lymphoma (NHL)
Monoclonal Antibodies
Therapeutics that bind to specific receptors on the surface of lymphoma cells and thereby induce their death.

Buyer Products:

  • Rituxan (Rituximab)
 
Palliative Agents  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics that treat neutropenia and other cancer related conditions of lymphomas of B-cells and T-cells by inducing the maturation and proliferation of granulocytes, macrophages and mixed granulocyte-macrophage colonies of cells.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Musculoskeletal System  
Metastatic  
Osteolytic Bone Metastases  
Osteoclast Bone Resorption Inhibitors
Therapeutics that treat and manage bone cancers that have spread beyond their original tumor site by preventing the loss of bone mass followed by deposition of new bone which can result in entrapped tumors below the new bone surface.

Target Products:

  • Berlex Bonefos (Clodronate)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1594 (Anti-CD20 Molecule )
  • R1668 (E2F Modulator)
  • E2F Activating Compound
  • AS1404
  • CAL (Anti-PTHrP Monoclonal Antibody)
  • CHC 12103 (Polyglutamate TXL)
  • AHM (Anti-HM 1.24 Monoclonal Antibody)
  • R1536 (Enzyme Inhibitor)
  • R1550 (Monoclonal Antibody)
  • R1492 (Enzyme Inhibitor)
  • KOS-862 (Epothilone D)
  • R1564/DMXAA (Vascular Targeting Agent)
  • Therex
  • Therafab
  • Pemtumomab/R1549
  • Diflomotecan (Topoisomerase Inhibitor I)
  • Trastuzumab-DM1
  • Avastin (Bevacizumab)
  • PRO64553 (Anti-CD40 Antibody)
  • R1273 (Monoclonal Antibody)
  • Tarceva (Erlotinib)

Target Products:

  • ZK-EPO (Epothilone)
  • Berlex MS-275 (Histone Deacytelators)
  • Oral Multi-target Tumor Growth Inhibitor (MTGI)
  • TOCOSOL Paclitaxel (S-8184)
  • Berlex PTK787 (Vatalanib)
  • Berlex MS209 (Multidrug Resistance Modulator)
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment and management of cancer and are currently in an early research or preclinical stage of development.

Buyer Products:

  • 2H7
  • R1491 (Angiogenesis Inhibitor)
  • R1453 (Enzyme Inhibitor)
  • PRO1762
  • R1559 (Enzyme Inhibitor)
  • R1454 (Enzyme Inhibitor)
  • P53 Pathway Activators
  • BN80927 (Topoisomerase I/II Inhibitor)
  • R547 (Enzyme Inhibitor)
  • R1645 (Enzyme Inhibitor)
  • R1630 (Enzyme Inhibitor)
 
Respiratory System/Thoracic  
Lung Cancer  
Non Small Cell Lung Cancer (NSCLC)  
Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors
Therapeutics that treat and manage cancers of the lung including squamous cell carcinoma, adenocarcinoma and large cell carcinoma by blocking the tyrosine kinase enzyme by switching off the signals from the epidermal growth factor receptors.

Buyer Products:

  • Tarceva (Erlotinib)
 
Monoclonal Antibodies
Therapeutics that treat lung cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
 
Urology
Kidney Cancer (Renal Cell Carcinoma)  
Metastatic  
Monoclonal Antibodies
Therapeutics that treat kidney cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Avastin (Bevacizumab)
 
Ovarian Cancer  
Adenocarcinoma  
Monoclonal Antibodies
Therapeutics that treat ovarian cancer by binding to specific structures on the surface of the tumor and eliciting a reaction, which results in tumor degeneration.

Buyer Products:

  • Pemtumomab/R1549
 
Uterine Cancer  
Uterine Fibroids (Leiomyoma, Uterus)  
Progestins Receptor Modulators
Therapeutics that treat and manage non-cancerous tumors of the uterus by modulating the effects of progesterone.

Target Products:

  • Berlex Asoprisnil
 
Ophthalmology  
Degenerative Disorders  
Macular Degeneration (AMD)  
Vascular Endothelial Growth Factor Inhibitors (VEGF)
Therapeutics that treat macular degeneration by binding to the vascular endothelial growth factor (VEGF) and inhibiting the formation of blood vessels in the eye.

Buyer Products:

  • Lucentis (Ranibizumab)
 
Retinitis  
AIDS-Related Cytomegalovirus (CMV) Retinitis  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of eye disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • Lucentis (Ranibizumab)
 
Pain Management  
Anesthesia  
General (Systemic)  
Adjunctive  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that result in anesthesia by enhancing the inhibitory neurotransmitter action of gamma-aminobutyric acid.

Buyer Products:

  • Versed (Midazolam)
 
Reversal  
Gamma-Aminobutyric Acid (GABA) Receptor Antagonists
Therapeutics that reverse general anesthesia by competitively inhibiting benzodiapizines at the GABA receptors, thus reducing their effect and reversing the anesthesia.

Buyer Products:

  • Romazicon (Flumazenil)
 
Non-Narcotics  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)  
Non-Specific Cyclooxygenase Inhibitors (COX Inhibitors)
Therapeutics that treat pain by non-specifically inhibiting the action of cyclooxygenase.

Buyer Products:

  • Naprosyn/EC-Naprosyn/Anaprox/Anaprox DS (Naproxen)
  • Toradol (Ketorolac Tromethamine)
  • Aleve (Naproxen Sodium)
 
Non-Steroidal Anti-Inflammatory Drugs (NSAID) Combinations  
Non-Steroidal Anti-Inflammatory Drugs (NSAID)/Decongestants
Therapeutic combinations that produce insensibility or numbness through the inhibition of prostoglandins while also preventing nasal decongestion.

Buyer Products:

  • Aleve Cold & Sinus (Naproxen/Pseudoephedrine)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of pain in early stages of clinical research where human subject is involved.

Buyer Products:

  • Bondronat (Ibandronate)
 
Respiratory System
Lower Respiratory Tract Disorders (Lung Disorders)  
Asthma  
Prophylactic Treatments  
Monoclonal Antibodies
Therapeutics that treat asthma with monoclonal antibodies.

Buyer Products:

  • Xolair (Omalizumab)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1295 (Integrin Antagonist)
  • R411 (Integrin Antagonist)
  • R448
  • R667 (Nuclear Receptor)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of respiratory disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1456 (Nuclear Receptor)

Target Products:

  • Cathepsin S Inhibitor
Surgery  
Cardiovascular System  
Complications  
Peripheral Arterial Occlusion  
Thrombolytic Agents
Therapeutics that treat diseases of the blood vessels outside the heart by dissolving blood clots.

Buyer Products:

  • Cathflo Activase (Alteplase)
 
Toxicology  
Substance Abuse  
Withdrawal  
Alcohol  
Gamma-Aminobutyric Acid (GABA) Receptor Agonists
Therapeutics that treat alcohol withdrawal by increasing the effect of GABA at the relevant neuroreceptors.

Buyer Products:

  • Valium (Diazepam)
 
Transplantation
Bone Marrow
Complications
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Cytovene (Ganciclovir)
 
Neutropenia  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics containing biological proteins that stimulate the formation of certain white blood cell colonies.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Heart  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Cytovene (Ganciclovir)
  • Valcyte (Valganciclovir Hydrochloride)
 
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that help manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
 
Hepatic (Liver)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
 
Lung  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Cytovene (Ganciclovir)
  • Valcyte (Valganciclovir Hydrochloride)
 
Pancreas  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Peripheral Blood Progenitor Cell Transplant (PBPCT)  
Recovery  
Colony Stimulating Factors (CSF)  
Granulocyte Macrophage (rhGM-CSF)
Therapeutics containing biological proteins that stimulate the formation of certain white blood cell colonies.

Target Products:

  • Berlex Leukine (Sargramostim)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the management of rejection and infection in early stages of clinical research where human subject is involved.

Buyer Products:

  • ISATX247 Trans
  • VAL (Liver Regenerator)
  • Raptiva (Efalizumab)
  • Zenapax (Daclizumab)
  • BCX-4208 (Second-Generation PNP Inhibitor)
  • R1524 (Calcineurin Inhibitor)
 
Renal (Kidney)  
Complications  
Cytomegalovirus (CMV) Infections  
Viral DNA Polymerase Inhibitors
Therapeutics that treat cytomegalovirus (CMV) infections by inhibiting a key enzyme necessary for viral replication.

Buyer Products:

  • Valcyte (Valganciclovir Hydrochloride)
  • Cytovene (Ganciclovir)
 
Rejection Prophylaxis  
Immunosuppressants
Therapeutics that manage and suppress the response of the immune system to foreign tissue.

Buyer Products:

  • CellCept (Mycophenolate Mofetil)
 
Monoclonal Antibodies
Protein-based therapeutics that target specific substances like proteins.

Buyer Products:

  • Zenapax (Daclizumab)
 
Urology
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R450 (GPCR Modulator)
  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
  • R701 (GPCR Antagonist)
  • R1484 (GPCR Modulator)

Target Products:

  • Progestogen Etonogestrel
  • Berlex Oxybutynin Releasing Vaginal Ring
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of urological disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1554 (GPCR Antagonist)
  • R873 (GPCR Agonist)
  • R1437 (GPCR Antagonist)
 
Urological Disorders  
Kidney (Renal)  
Chronic Renal Failure (CRF)  
Complications  
Anemia  
Recombinant Human Erythropoietins
Therapeutics that treat the condition resulting from the scarcity of red blood cells by inducing the production of red blood cells.

Buyer Products:

  • Mircera/CERA (Continuous Erythropoietin Receptor Activator)
 
Edema  
Loop Diuretic Agents
Therapeutics that treat the accumulation of abnormally large amounts of fluid in subcutaneous tissues by promoting the excretion of urine.

Buyer Products:

  • Bumex (Bumetanide)
  • Demadex (Torsemide)
 
Weight Management  
Obesity  
Lipase Inhibitors
Therapeutics that reduce the absorption of fat by inhibiting production of lipase, which is an enzyme that helps breaking down fat in the food.

Buyer Products:

  • Xenical (Orlistat)
 
Phase I/Phase II Clinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in early stages of clinical research where human subject is involved.

Buyer Products:

  • R1065 (GPCR Modulator)
 
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of weight disorders in very early stages of research where no human subject is involved.

Buyer Products:

  • R1496 (GPCR Modulator)
 
Wound Management  
Research/Preclinical Stage Products
Therapeutics that are being investigated for the treatment of wounds in very early stages of research where no human subject is involved.

Buyer Products:

  • Vascular Endothelial Growth Factor
 
Medical Devices
Cardiology  
Diagnostic  
Imaging  
Magnetic Resonance Imaging (MRI)  
Contrast Agents
A drug that is introduced into a patient to attain better image quality.

Target Products:

  • Gadofluorine Derivative
  • Berlex Vasovist (Gadofosveset)
 
X-Ray  
Angiography  
Accessories
Various instruments used to assist in angiography procedures, including transducers, catheters, control syringes, waste systems, contrast management systems, fluid administration sets, and other related items.

Target Products:

  • Medrad Mark V ProVis Injection System
  • Medrad Mark Series
 
Monitoring  
Monitors  
Vitals/Multiple Parameter  
Electrocardiogram (ECG/EKG)/Pulse Oximeter (SpO2)/ Multiple Vitals  
Portable
Device that measures, records, and displays the electrical signals of the heart, the oxygen concentration in the blood, the blood pressure with direct access to an artery and blood pressure with out direct access to an artery and can be moved around with the patient.

Target Products:

  • Medrad 9500 Vital Signs Patient Monitor
 
Clinical Diagnostics  
Chemistry  
Analyzers  
Blood Gas
Analyzers used to measure blood gases for diagnostic purposes.

Buyer Products:

  • Roche Diagnostics AVL Compact 1-3
  • Roche Diagnostics AVL 988 Series
  • Roche Diagnostics OMNI Series
 
Discrete  
Limited Assay
Discrete analyzers with limited test menu.

Buyer Products:

  • Roche Diagnostics AVL 9180 Series
  • Roche Diagnostics OMNI Series
 
Multiple Assay
Multi-System analyzers designed for high throughput generally used in high volume clinical laboratories.

Buyer Products:

  • Roche Diagnostics Cobas Integra Series
  • Roche Diagnostics Roche/Hitachi 902/912
  • Roche Diagnostics Reflotron Series
 
Home Testing  
Cholesterol
Home test kits which test for cholesterol levels in patient blood.

Buyer Products:

  • Roche Diagnostics Accu-Chek Plus
  • Roche Diagnostics Accutrend System
 
Glucose  
Invasive
Devices that generally use blood samples for testing and require a needlestick or pin-prick.

Buyer Products:

  • Roche Diagnostics Accu-Chek Active Meter
  • Roche Diagnostics Accu-Chek Advantage/Advantage II/Sensor Meter
  • Roche Diagnostics Accu-Chek Complete/Sensor Complete Meter
  • Roche Diagnostics Accu-Chek Compact Meter
  • Roche Diagnostics Accu-Chek Plus
  • Roche Diagnostics Accu-Chek Simplicity
  • Roche Diagnostics Accu-Chek Instant DM
  • Roche Diagnostics Accu-Chek Aviva
 
Test Strips
Specific glucose test devices used with glucose monitors.

Buyer Products:

  • Roche Diagnostics Accu-Chek Go
  • Roche Diagnostics Accu-Chek Advantage Test Strips
  • Roche Diagnostics Accu-Chek Simplicity Test Strips
  • Roche Diagnostics Accu-Chek Compact Test Drums
  • Roche Diagnostics Accu-Chek Comfort Curve/Sensor Comfort/Advantage Comfort/Advantage II Test Strips
  • Roche Diagnostics Accu-Chek Active Test Strips
  • Roche Diagnostics Glucotrend Strips
 
Point of Care Testing  
Critical Care Analysis  
Analyzers
Chemistry analyzers which may be used for the chemical analysis of body fluids and designed for use at the bedside during the course of patient care.

Buyer Products:

  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Elecsys 1010
 
Test Cartridges
Specific analyte test devices used in conjunction with critical care chemistry analyzers.

Buyer Products:

  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Elecsys 1010
 
Glucose Monitoring  
Invasive  
Continuous Analysis
Glucose test devices which measure patient glucose levels on a continual basis.

Buyer Products:

  • GlucOnline Microdialysis System
 
Random Analysis
Glucose test devices which measure patient glucose levels as a blood sample is obtained.

Buyer Products:

  • Roche Diagnostics Accu-Chek Inform System
  • Roche Diagnostics AccuData GTS/AccuData HDM
 
Kits  
Cardiac
Test kits used to aid in the diagnosis of heart conditions.

Buyer Products:

  • Roche Diagnostics Cardiac D-Dimer
 
Reagents  
Calibrators  
Routine Analyte  
Multiple
Calibrators which contain multiple specific analytes used to establish the accuracy of chemistry analyzers.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Single
Calibrators which contain a specific analyte used to establish the accuracy of chemistry analyzers.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Controls  
Routine
Controls used to test the accuracy of discrete chemistry test systems.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Test Kits  
Pharmacogenetic
Test kits designed to determine individuals' reaction to specific medications based on their specific genes.

Buyer Products:

  • Roche Diagnostics AmpliChip CYP450 Test
 
Hemostasis/Coagulation  
Analyzers  
Automated
Automated coagulation analyzers.

Buyer Products:

  • Roche Diagnostics Stago Sta Compact
  • Roche Diagnostics Stago Sta R
 
Reagents  
Test Kits  
Prothrombin Time
Reagents used to perform prothrombin time assays.

Buyer Products:

  • Roche Diagnostics CoaguChek Series
 
Immunoassays  
Analyzers  
Autoimmune
Analyzers used to perform autoimmune testing.

Buyer Products:

  • Roche Diagnostics COBAS AmpliPrep System
  • Roche Diagnostics COBAS AMPLICOR Analyser
 
Multiple Assay
Immunoassay analyzer designed to perform multiple assays over multiple modalities.

Buyer Products:

  • Roche Diagnostics Cobas Core II
  • Roche Diagnostics E170
  • Roche Diagnostics Elecsys 2010
  • Roche Diagnostics Elecsys 1010
 
Reagents  
Calibrators  
Therapeutic Drugs
Calibrators used in the measurement of therapeutic drugs.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Toxicology/Abuse Drugs
Calibrators used in the measurement of drugs of abuse.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Controls  
Therapeutic Drugs
Controls which contain known concentrations of specific therapeutic drugs used to verify the performance of therapeutic drug testing systems.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Test Kits  
Bacterial  
Chlamydia
Immunoassay kits which test for current or previous infection caused by the Chlamydia organism.

Buyer Products:

  • Roche Diagnostics COBAS AMPLICOR CT/NG Test/AMPLICOR CT/NG Test
 
Tuberculosis
Immunoassay test kits which quantitatively measure tuberculosis antibody in plasma or serum.

Buyer Products:

  • Roche Diagnostics Amplicor M. tuberculosis Test
 
Radioimmunoassays  
Cancer Marker
Radioimmunoassay test kits which measure for cancer markers in plasma or serum.

Buyer Products:

  • Roche Diagnostics Cobas Core Reagent Series
 
Cardiac
Radioimmunoassay test kits which measure for analytes associated with heart disease in plasma or serum.

Buyer Products:

  • NT-proBNP
 
Special/Immuno Chemistry  
Cancer Marker  
Breast
Diagnostic assay used to detect specific breast tumor or cancer markers.

Buyer Products:

  • BCM 18 (Breast Cancer Marker)
 
Colorectal (Colon)
Diagnostic assay used to detect specific colorectal (colon) tumor or cancer markers.

Buyer Products:

  • Roche Diagnostics hemo FEC
 
Cardiac  
Myocardial Infarction/Heart Failure  
Myoglobin
Immunoassay test kits which quantitatively measure for myoglobin in plasma or serum.

Buyer Products:

  • Roche Diagnostics Cardiac Reader
 
Troponin
Immunoassay test kits which quantitatively measure for troponin in plasma or serum.

Buyer Products:

  • Roche Diagnostics TROPT Sensitive
  • Roche Diagnostics Cardiac Reader
 
Therapeutic Drugs
Immunoassay test kits which quantitatively measure for therapeutic drugs in serum or urine using automated instrumentation..

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
 
Toxicology/Abuse Drugs  
Multiple Drug Kit
Immunoassay test kits which measure for more than one drug of abuse in body fluids.

Buyer Products:

  • Roche Diagnostics Cobas Integra Reagents Series
  • Roche Diagnostics OnTrak TesTcard 9
 
Viral  
Human Immunodeficiency Virus (HIV)  
Serum  
Genotyping
Tests that "fingerprint" HIV according to chromosomal makeup in order to track specific strains.

Buyer Products:

  • Roche Diagnostics COBAS Amplicor HIV-1 Test
  • Roche Diagnostics AMPLICOR HIV-1 Monitor Test
  • Roche Diagnostics Amplicor HIV-1 Test
 
Microbiology  
Genetic Probes/PCR  
Reagents  
Bacterial  
Tuberculosis
Genetic probe for detection and/or quantitation of Mycobacterium tuberculosis.

Buyer Products:

  • Roche Diagnostics COBAS AMPLICOR MTB Test/AMPLICOR MTB Test
  • Roche Diagnostics COBAS AMPLICOR Mycobacterium avium Test/AMPLICOR MAV Test
  • Roche Diagnostics COBAS AMPLICOR Mycobacterium Intracellular (MIN) Test/AMPLICOR MIN Test
 
Viral  
Cytomegalovirus
Genetic probe for detection and/or quantitation of Cytomegalovirus.

Buyer Products:

  • Roche Diagnostics AMPLICOR CMV Test
  • Roche Diagnostics COBAS AMPLICOR CMV Monitor Test
 
Hepatitis B Virus
Genetic probes for detection and/or quantitation of HBV.

Buyer Products:

  • Roche Diagnostics AMPLINAT MPX Test
  • Roche Diagnostics COBAS AmpliScreen HBV Test
 
Hepatitis C Virus
Genetic probes for detection and/or quantitation of HCV.

Buyer Products:

  • Roche Diagnostics COBAS AMPLICOR HCV Monitor Test/AMPLICOR HCV Monitor Test
  • Roche Diagnostics COBAS AmpliScreen HCV Test
  • Roche Diagnostics AMPLINAT MPX Test
  • Roche Diagnostics COBAS AMPLICOR HCV Test/AMPLICOR HCV Test
 
Human Immunodeficiency Virus (HIV)
Genetic probes for detection and quantification of HIV.

Buyer Products:

  • Roche Diagnostics COBAS AmpliScreen HIV-1 Test
  • Roche Diagnostics Amplicor HIV-1 Test
  • Roche Diagnostics AMPLINAT MPX Test
 
Human Papilloma Virus
Genetic probes for the detection of HPV.

Buyer Products:

  • Roche Diagnostics Digene Hybrid Capture II HPV Test
 
West Nile Virus
Genetic probe for detection and/or quantitation of West Nile Virus.

Buyer Products:

  • Roche Diagnostic TaqScreen West Nile Virus Test
 
Specimen Collection  
Blood  
Capillary  
Lancets
Sharps type of device used to puncture the skin in order to collect a capillary blood sample.

Buyer Products:

  • Roche Diagnostics Accu-Chek Autoclix Lancing System
  • Roche Diagnostics Softclix Pro Lancets
  • Roche Diagnostics Safe-T-Pro Lancets
  • Roche Diagnostics SoftTouch Lancets
 
Urinalysis  
Analyzers  
Chemistry
Analyzers used to perform chemical analysis of urine.

Buyer Products:

  • Roche Diagnostics Urisys 2400
  • Roche Diagnostics Miditron M
  • Roche Diagnostics Miditron Junior II
  • Roche Diagnostics Urisys 1100
 
Reagents  
Test Strips
Reagents, in a embedded strip format, used to perform chemical, and physical analysis of urine or body fluids.

Buyer Products:

  • Roche Diagnostics Chemstrip Series
 
Neurology  
Surgical  
Region Specific  
Brain  
Stereotactic Surgery  
Guidance/ Planning Systems
Imaging equipment and/or computer systems that create a 3D map of the interior of the brain facilitating stereotactic surgery.

Target Products:

  • Medrad SimpliCT
 
Oncology  
Diagnostic  
Imaging  
MRI  
Contrast Agents
A drug that is introduced into a patient to attain better MRI image quality.

Target Products:

  • Berlex Vasovist (Gadofosveset)
 
Radiology  
Computed Tomography (CT) Scan  
Accessories  
CT Contrast Injectors
Devices that mechanically push contrast agent into the patient.

Target Products:

  • Medrad EnVision CT
  • Medrad Stellant CT
  • Medrad Vistron CT
 
Syringes
Disposables used in contrast injection pumps.

Target Products:

  • Medrad Angiomat 3000/6000/6000CT
  • Medrad 100/200/300 Series
  • Medrad EnVision CT Front Load
  • Medrad MCT Plus Front Load
  • Medrad Viamonte-Hobbs 2000
  • Medrad Vistron CT Front Load
 
Contrast Agents  
Injectable
CT Scan contrast agents administered by injection.

Target Products:

  • Berlex Neotect (Kit for the Preparation of Technetium Tc 99m Depreotide Injection)
  • Berlex Acutect (Kit for the Preparation of Technetium Tc 99m Apcitide Injection)
  • Berlex Ultravist (Iopromide)
 
MRI  
Accessories  
Needle Systems
Injection systems used to deliver MRI contrast agents.

Target Products:

  • Medrad Spectris Solaris MR Injection Series
  • Medrad Continuum MR Compatible Infusion System
  • Medrad Spectris MR
 
Coils  
Closed MRI  
General Purpose
A closed MRI system that is designed to be used for multiple purpose imaging studies.

Target Products:

  • Medrad Multi-Purpose Array
 
Region Specific  
Abdominal
A coil that is placed on the abdomen to attain an image.

Target Products:

  • Medrad MRInnervu
  • Medrad Torso Array
 
Breast
A coil that is placed on the breast to attain an image of it.

Target Products:

  • Medrad Breast Coil/Array
 
Head/Neck
A coil that is placed on or around the head/neck to attain an image of it.

Target Products:

  • Medrad Neurovascular Array
  • Medrad Anterior Neck Coil
 
Lower Extremity
A coil that is placed on the lower extremity to attain an image of it.

Target Products:

  • Medrad Extremity Array
 
Spine
A coil that is placed near the spine to attain an image of it.

Target Products:

  • Medrad Quadrature Cervical Thoracic-Lumbar Array
 
Upper Extremity
A coil that is placed on an upper extremity to attain an image of it.

Target Products:

  • Medrad Extremity Array
  • Medrad Shoulder Coil
 
Vascular
A coil that is placed near a vessel to attain an image of it.

Target Products:

  • Medrad Gore Cardiovascular Array
 
Contrast Agents  
Injectable
A contrast agent that gets introduced to the body via a needle or IV.

Target Products:

  • Berlex Eovist
  • Berlex Magnevist (Gadopentetate Dimeglumine)
  • Berlex Feridex I.V. (Ferumoxide)
  • Berlex Vasovist (Gadofosveset)
  • Berlex SHU 555C
  • Berlex Primovist (Gadoxetic Acid)
  • Berlex Gadovist (Gadobutrol)
  • Berlex Resovist
 
Ultrasound  
Accessories  
Aspiration Needles
Biopsy needles that have special properties allowing ultrasound guidance.

Target Products:

  • Medrad Pulsar Injection System
 
X-Ray  
Contrast Agents  
Injectable
Introduced to the body via a needle.

Target Products:

  • Berlex Ultravist (Iopromide)
  • SF-64 (Omocianine)
 
Urology  
Diagnostic  
Imaging  
MRI  
Contrast Agents
A drug that is introduced into a patient to attain better MRI image quality.

Target Products:

  • Berlex Vasovist (Gadofosveset)
 
Vascular  
Diagnostic  
Imaging  
X-Ray  
Angiography  
Accessories
Various instruments used to assist in angiography procedures, including transducers, catheters, control syringes, waste systems, contrast management systems, fluid administration sets, and other related items.

Target Products:

  • Medrad Mark Series
 
Scientific Products  
Analytical Instruments  
Analyzers  
Gas Monitors  
Multiple Component  
Benchtop
Multi-component gas monitors that are generally located on the counter top.

Buyer Products:

  • Roche Diagnostics AVL OMNI 1-9
 
Bioanalytical Instruments  
Biomolecular  
Microplate Readers  
Systems  
Multiple Parameter
Microplate reader systems that used a combination of fluorescent, luminescent, and/or photoemission detectors.

Buyer Products:

  • Roche Diagnostics Lumi-Imager
 
Sequencers  
Automated  
Nucleic Acid
Automated gel electrophoresis or capillary electrophoresis sequencers used to analyze nucleic acid sample.

Buyer Products:

  • Genome Sequencer 20
 
Synthesizers  
Peptides
Synthesizer systems used for the identification and synthesis of peptide samples.

Buyer Products:

  • Roche Diagnostics Rapid Translation System
 
Thermal Cyclers  
Accessories
Supplementary products used to enhance the performance of a thermal cycler.

Buyer Products:

  • Roche Diagnostics MagNA Pure LC
 
Systems
Thermal cycler components assembled as a single unit.

Buyer Products:

  • Roche Diagnostics LightCycler
 
Consumables  
Bioanalytical Chemistry  
Molecular Biology  
Microarray Technology  
Microarray Chips
Microarray/biochip components that give detailed analysis of differential expression in normal and diseased or treated cells.

Buyer Products:

  • Roche Diagnostics AmpliChip CYP 450
 
Nucleic Acid Analysis  
Kits  
Nucleic Acid  
Transfection
Nucleic acid analysis kits that are used for the introduction of DNA into a recipient eukaryote cell and its subsequent integration into the recipient cells chromosomal DNA

Buyer Products:

  • Roche Diagnostics FuGENE
 
General Laboratory Equipment  
Automation Equipment  
Robotic Instruments  
Workstations
Robotic instrument systems that transfer liquid and gas samples and also heat and cool samples.

Buyer Products:

  • Roche Diagnostics Task Targeted Automation
 

- Focused. Denotes that the company is considered focused in this area. In general, Focused Companies draw the majority of their earnings in the sector/product area specified.

- Sector Pure-Plays. Denotes that the company is focused in the selected sector and generates nearly all earnings in the sector/product area specified.

- Sector Participation. Denotes that the company develops products in this line of business.

Relationship Details

Key Competitors

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Amgen, Inc. n/a 84,572.553 28.76 19.18 6.17 5.98 31.37
Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Altana AG (ADR) n/a 7,901.267 12.40 13.47 3.28 n/a 3.62
Barr Pharmaceuticals, Inc. n/a 5,376.860 17.57 15.38 4.02 3.70 4.32
The Medicines Company n/a 1,388.930 318.19 90.77 7.48 6.53 6.95
GPC Biotech AG (ADR) n/a 681.567 n/a n/a 26.01 n/a 6.76
Neurocrine Biosciences, Inc. n/a 378.840 n/a -3.13 8.63 11.84 1.16
Immunomedics, Inc. n/a 152.476 n/a n/a 21.00 n/a n/a
Point Therapeutics, Inc. n/a 30.471 n/a -0.99 101.09 57.66 1.44
Buyer
  Pfizer Inc. n/a 193,888.862 15.37 13.35 4.01 4.07 8.31
Johnson & Johnson n/a 190,922.506 17.25 17.85 3.65 3.63 7.01
Target
  Roche Holding Ltd. (ADR) n/a 157,245.145 34.89 24.82 5.69 n/a 8.62
Genentech, Inc. n/a 84,941.939 45.71 40.64 10.04 9.42 12.00
Amgen, Inc. n/a 84,572.553 28.76 19.18 6.17 5.98 31.37
Teva Pharmaceutical Industries Ltd (ADR) n/a 25,046.770 64.06 14.03 3.33 2.95 34.79
Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Altana AG (ADR) n/a 7,901.267 12.40 13.47 3.28 n/a 3.62
Elan Corporation, plc (ADR) n/a 6,402.804 n/a -19.09 11.98 11.94 n/a
Barr Pharmaceuticals, Inc. n/a 5,376.860 17.57 15.38 4.02 3.70 4.32
Warner Chilcott Ltd. n/a 3,397.557 n/a 24.98 4.95 4.66 n/a
Medicis Pharmaceutical Corporation n/a 2,078.941 n/a 48.94 6.28 5.89 8.62
MGi Pharma, Inc. n/a 1,532.097 n/a -107.28 4.46 4.36 n/a
The Medicines Company n/a 1,388.930 318.19 90.77 7.48 6.53 6.95

- Defined by the Company - Defined by Others

Dependent Suppliers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Crucell N.V. (ADR) n/a 1,397.634 n/a -13.44 14.23 7.49 3.80
Dendrite International, Inc. n/a 511.778 n/a 53.45 1.22 1.23 3.77
Bioject Medical Technologies Inc. n/a 14.847 n/a n/a 1.55 n/a 2.54
Buyer
  Aspreva Pharmaceuticals Corporation 100.00% 668.666 5.46 5.88 3.22 3.18 2.62
Emisphere Technologies Inc. 80.40% 164.318 n/a -4.88 23.04 48.40 n/a
deCODE genetics, Inc. 23.00% 292.909 n/a -3.39 7.54 7.32 n/a
PDL BioPharma Inc. 3.30% 2,676.705 n/a 90.04 6.85 6.27 26.44
sanofi-aventis (ADR) n/a 116,539.433 30.70 13.50 3.12 3.28 n/a
Target
  Advanced Magnetics, Inc. 47.00% 683.619 n/a -60.21 250.37 498.12 15.35
Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Millennium Pharmaceuticals, Inc. n/a 3,612.192 n/a -286.50 7.70 7.57 6.47
Medarex, Inc. n/a 1,644.559 n/a -9.34 29.36 34.19 4.46
Crucell N.V. (ADR) n/a 1,397.634 n/a -13.44 14.23 7.49 3.80
Dendrite International, Inc. n/a 511.778 n/a 53.45 1.22 1.23 3.77
Penwest Pharmaceuticals n/a 422.847 n/a -13.24 114.56 110.91 8.71
OPNET Technologies, Inc. n/a 332.082 60.23 43.76 3.79 3.42 3.71
Peregrine Pharmaceuticals n/a 246.122 n/a n/a 72.26 n/a 8.49
EPIX Pharmaceuticals, Inc. n/a 125.667 n/a -2.99 20.31 15.99 n/a
Pharmacopeia Drug Discovery, Inc. n/a 85.337 n/a -2.54 4.44 4.80 4.51
Bioject Medical Technologies Inc. n/a 14.847 n/a n/a 1.55 n/a 2.54
Tripos, Inc. n/a 7.810 n/a n/a 0.18 n/a 0.38
Valentis, Inc. n/a 7.687 n/a n/a 10.58 n/a 3.16

- Defined by the Company - Defined by Others

Key Customers

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Buyer
  Applera Corporation n/a 6,752.947 38.97 27.64 3.42 3.31 5.91
PDL BioPharma Inc. n/a 2,676.705 n/a 90.04 6.85 6.27 26.44
MDS Inc. (USA) n/a 2,667.679 67.96 30.20 1.99 2.14 4.78
IDEXX Laboratories, Inc. n/a 2,650.065 29.77 31.15 3.71 3.61 10.40
Gen-Probe Incorporated n/a 2,617.338 43.60 45.06 7.44 7.38 5.23
Aspreva Pharmaceuticals Corporation n/a 668.666 5.46 5.88 3.22 3.18 2.62
Connetics Corporation n/a 597.988 n/a -28.85 4.10 3.60 n/a
Grupo Casa Saba, S.A. (ADR) n/a 592.947 8.35 n/a 0.28 n/a 1.31
Abaxis, Inc. n/a 415.428 47.80 43.63 5.28 n/a 5.29
Enzon Pharmaceuticals, Inc. n/a 368.304 n/a 16.78 2.19 1.99 n/a
Trimeris, Inc. n/a 255.860 39.63 50.91 9.35 7.57 8.86
IRIS International, Inc. n/a 166.138 357.61 31.73 2.52 2.43 3.14
Allion Healthcare, Inc. n/a 96.572 26.56 27.00 0.51 0.44 3.43
Target
  Millennium Pharmaceuticals, Inc. n/a 3,612.192 n/a -286.50 7.70 7.57 6.47
Cotherix, Inc n/a 384.762 n/a -14.06 6.41 5.57 4.49
Sonus Pharmaceuticals, Inc. n/a 213.430 n/a -7.65 8.62 8.95 4.34
Favrille, Inc. n/a 101.704 n/a -2.25 n/a n/a 1.89
Accentia Biopharmaceuticals, Inc n/a 100.865 n/a -2.34 3.72 3.31 n/a

- Defined by the Company - Defined by Others

Key Partners

  Name Dir Percent Market Cap. P/E Ratio (TTM) Fwd P/E P/R Ratio (TTM) Fwd P/Rev Price To Tang. Book Value
Overlap
  Novartis AG (ADR) n/a 137,962.635 20.11 18.92 3.81 3.74 3.58
Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Medarex, Inc. n/a 1,644.559 n/a -9.34 29.36 34.19 4.46
Valentis, Inc. n/a 7.687 n/a n/a 10.58 n/a 3.16
Buyer
  GlaxoSmithKline plc (ADR) n/a 148,888.977 14.59 14.60 3.36 3.42 14.57
Novartis AG (ADR) n/a 137,962.635 20.11 18.92 3.81 3.74 3.58
Target
  Pfizer Inc. n/a 193,888.862 15.37 13.35 4.01 4.07 8.31
Novartis AG (ADR) n/a 137,962.635 20.11 18.92 3.81 3.74 3.58
AstraZeneca plc (ADR) n/a 89,001.730 15.25 14.69 3.48 3.38 8.92
Abbott Laboratories n/a 72,061.862 22.74 18.94 3.23 3.25 28.77
3M Company n/a 59,756.110 17.39 17.98 2.66 2.62 9.21
Koninklijke Philips Electronics NV (ADR) n/a 43,560.190 6.91 33.58 1.23 1.30 1.83
Biogen Idec Inc. n/a 17,365.400 105.62 24.29 6.66 6.52 5.90
Genzyme Corporation n/a 17,130.299 47.84 29.82 5.60 5.42 5.69
Serono S.A. (ADR) n/a 13,657.170 19.97 19.08 4.99 4.87 5.65
Vertex Pharmaceuticals Incorporated n/a 5,639.027 n/a -22.12 30.34 26.84 11.11
Millennium Pharmaceuticals, Inc. n/a 3,612.192 n/a -286.50 7.70 7.57 6.47
Warner Chilcott Ltd. n/a 3,397.557 n/a 24.98 4.95 4.66 n/a
Bausch & Lomb Inc. n/a 2,676.622 17.99 72.25 1.14 1.14 4.69
Medarex, Inc. n/a 1,644.559 n/a -9.34 29.36 34.19 4.46
Pharmion Corporation n/a 741.256 n/a -53.34 3.15 3.18 3.38
Advanced Magnetics, Inc. n/a 683.619 n/a -60.21 250.37 498.12 15.35
Penwest Pharmaceuticals n/a 422.847 n/a -13.24 114.56 110.91 8.71
Indevus Pharmaceuticals n/a 403.455 n/a -7.71 8.89 8.48 n/a

- Defined by the Company - Defined by Others

Financials

  Buyer Target Combined Entity
Income Statement
Operating Items
Revenue 27,655.5 7,009.5 34,664.9
Other Revenue 0.0 0.0 0.0
Total Revenue 27,655.5 7,009.5 34,664.9
Cost of Revenue 7,245.8 1,624.0 8,869.9
SG&A Expense 9,277.7 2,887.9 12,165.5
Depreciation & Amortization 787.4 0.0 787.4
Research & Development 4,443.0 1,283.9 5,726.9
Interest Expense 0.0 0.0 0.0
Other Operating Expense -1,126.9 119.2 -1,007.7
Unusual Expense (Income) 277.2 0.0 277.2
Total Expenses 20,904.2 5,915.1 26,819.2
Operating Income 6,751.3 1,094.4 7,845.7
Non Operating Items
Interest Expense (Inc.), Net Non-Oprtng 231.3 18.8 250.1
Other, Net 0.0 28.9 28.9
Income Before Taxes 6,982.6 1,142.1 8,124.7
Income Taxes 1,732.0 384.0 2,116.1
Income After Taxes 5,250.6 758.1 6,008.6
Minority Interest (IS) -734.4 -5.0 -739.4
Net Income - Excl. Xord. Items 4,516.2 753.0 5,269.2
Discontinued Operations -9.3 0.0 -9.3
Net Income - Incl. Xord. Items 4,506.8 753.0 5,259.9
Income Avail. to Common 4,506.8 753.0 5,259.9
Share Items
Basic Avg. Shares Outstanding 1,690.0 192.4 1,882.4
Basic EPS - Excl. Xord. Items 5.34 3.91 2.80
Basic EPS - Incl. Xord. Items 2.67 3.91 2.79
Full Dilution Adjustment 0.0 0.0 0.0
Fully Diluted Shares Outstanding 1,720.0 192.4 1,912.4
F.D. EPS - Excl. Xord. Items 2.63 3.91 2.76
F.D. EPS - Incl. Xord. Items 2.62 3.91 2.75
Dividends Per Common Share 0.97 1.51 2.48
Balance Sheet
Assets
Cash and Equivalents 3,292.7 1,445.8 4,738.5
ST Investments 12,972.2 94.1 13,066.4
Accounts Receivable 5,995.1 1,865.0 7,860.1
Inventory 3,925.9 1,070.6 4,996.4
Other Current Assets 1,559.1 0.0 1,559.1
Current Assets 27,745.0 4,475.5 32,220.5
Accum D&A 0.0 0.0 0.0
PPE, Net 11,757.3 1,408.2 13,165.5
Goodwill & Intangibles 9,647.6 829.6 10,477.2
Long Term Investments 1,750.7 268.6 2,019.3
Other Assets 0.0 0.0 0.0
Other LT Assets 3,119.8 396.6 3,516.4
Total Assets 54,020.5 7,378.4 61,398.9
Liabilities
Accounts Payable 1,848.1 0.0 1,848.1
Payable/Accrued 0.0 0.0 0.0
Accrued Expenses 3,992.8 0.0 3,992.8
ST Debt 0.0 0.0 0.0
Curr Port of LTD & Cap Lease Oblg 271.0 30.1 301.1
Other (Current) Liabilities 1,280.3 1,907.7 3,188.0
Current Liab. 7,392.2 1,937.8 9,330.0
LT Debt 7,259.8 268.6 7,528.4
Total LT Debt 7,259.8 268.6 7,528.4
Minority Interest (BS) 5,312.1 23.8 5,335.9
Deferred Taxes 2,739.8 0.0 2,739.8
Other LT Liab. 4,119.8 850.9 4,970.7
Total Liabilities 26,823.7 3,081.2 29,904.9
Shareholders Equity
Common Stock 124.6 243.5 368.1
Additional Paid in Capital 0.0 419.2 419.2
Retained Earnings 29,786.2 3,638.4 33,424.6
Treasure Stock -2,714.1 -3.8 -2,717.8
Other Equity 0.0 0.0 0.0
Total Equity 27,196.8 4,297.3 31,494.1
Total Liab. & Equity 54,020.5 7,378.4 61,398.9
Shares Outstanding 1,725.1 190.8 1,915.9
Cash Flow
Operating Cash Flow
CF Net Income 0.0 758.1 758.1
CF Depreciation 0.0 430.5 430.5
CF Deferred Taxes 0.0 0.0 0.0
Other Non-Cash Items -411.2 -86.6 -497.8
Change in Working Capital 5,142.3 356.4 5,498.8
Total Cash From Operating Activities 4,731.1 1,458.4 6,189.5
Investing Cash Flow (not calculated)
Capital Expenditures -1,464.9 -377.8 -1,842.7
Other Investing Cash Flows -2,600.4 -7.5 -2,607.9
Total Cash From Investing Activities -4,065.3 -385.3 -4,450.6
Financing Cash Flow (not calculated)
Dividends Paid -1,393.2 -291.2 -1,684.4
Purchase Or Sale of Stock -1,575.5 74.0 -1,501.4
Purchase and Retirement of Debt -735.2 0.0 -735.2
Other Financing Cash Flow 1,221.1 -579.8 641.3
Total Cash From Financing Activities -72.4 -797.0 -869.4
Exchange Rate Effects -68.5 -12.6 -81.1
Net Change in Cash 524.9 263.6 788.5
Cash Taxes Paid 603.6 252.3 855.8
Cash Interest Paid 151.1 15.1 166.1